140 research outputs found
Deeper ‘GO’ Phase in Rat Fibroblasts Affects the Lag Time Required for T Antigen Induced DNA Synthesis, but not the Lag Time Required for SV40 T Antigen Expression
No full text脂肪滴はヒト肝細胞株におけるPorphyromonas gingivalisのオートファジー・リソソームシステムを介した排除機構に影響する
No full textRecent studies have shown that infection with Porphyromonas gingivalis, a major periodontal pathogen, hastens the progression of non-alcoholic fatty liver disease (NAFLD). However, the intracellular fate of P. gingivalis in hepatocytes remains unknown. Here, using oleic-acid-induced HepG2 cells as an in vitro model for NAFLD, we found that lipid droplets increased the existence of P. gingivalis in the cells at an early phase of infection. Confocal microscopic analysis revealed that lipid droplets affected the formation of autolysosomes in infected cells. Thus, lipid droplets affect the elimination of P. gingivalis in HepG2 cells by altering the autophagy-lysosome system.長崎大学学位論文 学位記番号:博(医歯薬)甲第916号 学位授与年月日:平成29年3月21日Author: Yumi Zaitsu, Mayumi Iwatake, Keiko Sato, Takayuki TsukubaCitation: Microbes and Infection, 18(9), pp.565-571;201
Arrest states in a set of mutants of rat 3Y1 cells temperature‐sensitive for entering S phase
No full text東インドと隣接諸王国における珍奇なものに関する略説」 ー ライプツィッヒの外科医兼商人カスパル・シャムベルゲルの生涯と業績に関する新発見 ー
No full textEinleitung / Abriss eines abenteuerlichen Lebens / Zurück aus Ostindien – Schamberger in Leipzig / Zum Druck der Schambergerschen Erläuterung/ Struktur und Besonderheiten der drei Schildereyen / Mitbringsel aus der Fremde / Frühe Ostindien-Fahrer und ihre Bildmaterialien / Caspar Schmalkalden / Zacharias Wagener / Heinrich Muche / Johann Wilhelm Vogel / Elias Hesse / Albrecht Herport / George Meister / Andreas Cleyer / Engelbert Kaempfer / Zum Inhalt der Schambergerschen »Erläuterung« / Handel und Wandel der Niederländer in Ostindien / Früchte, Wurzeln, Nüsse / Tiere / Münzen / Ethnische Abbildungen / Sprache und Schrift / Rückblick / Text: Dreier in Untertänigkeit offerierten Schildereien kurze Erläuterung / Quellen und Literatur / Handschriftliche Quellen / Gedruckte Quellen (16.-18. Jh.) / Sekundärliteratur / Allgemeine Nachschlagewerke / RegisterThis book presents a newly discovered text of which only one copy has survived in the Dresden State Art Collections (Staatliche Kunstsammlungen Dresden, Münzkabinett). It was dedicated to the Duke of Saxony Johann Georg III. and published in 1686 as a private print under the title \u22Short explanation of the most prominent rarities in East India and the neighbouring kingdoms\u22. The author Caspar Schamberger (1623-1706) had worked in Asia for twelve years as a surgeon on VOC ships and in Dutch trading posts. He is known as the \u22father\u22 of the first fully-fledged Western-style medical school in Japan. His text describes fruits, plants, animals, ethnic groups, coins etc. from Persia to Japan including the Khoikhoi (Khoisan) in Southern Africa. This is one of the earliest Western accounts of these matters based on observations made during the late 1640s and 1650s. The extensive commentary (126 pages) gives an outline of Schamberger\u27s life presenting numerous new information on his activities after his return to Leipzig in 1658. Schamberger\u27s descriptions are analysed in detail within the context of similar accounts of nine contemporary German travellers: Caspar Schmalkalden, Zacharias Wagener, Heinrich Muche, Johann Wilhelm Vogel, Elias Hesse, Albrecht Herport, George Meister, Andreas Cleyer, Engelbert Kaempfer. Forty-six illustrations selected from Western and Japanese sources proviede the iconographic background
Preparation of S-acetylthioglycoloyl Insulins Based on Separation by Anion-Exchange High-Performance Liquid Chromatography.
No full textGeneration of a 12-fs ultraviolet optical pulse using two types of coherent molecular rotations
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Novel Dynamic Reconfigurable FPGA based on Multi-Context Scheme Using One-Time Memory with Gate-Induced Permanent Path
No full textAutocorrelator consisting of a solar-blind photomultiplier for use in the near-ultraviolet region
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