129 research outputs found
DS_10.1177_2380084419875442 – Supplemental material for An International Working Definition for Quality of Oral Healthcare
No full textSupplemental material, DS_10.1177_2380084419875442 for An International Working Definition for Quality of Oral Healthcare by A.J. Righolt, M.F. Walji, J.S. Feine, D.M. Williams, E. Kalenderian and S. Listl in JDR Clinical & Translational Research</p
ROER4D Project Activity Toolkit - Communication
No full textThe Research on Open Educational Resources for Development (ROER4D) project was a four-year (2013–2017), large-scale networked project which set out to contribute a Global South research perspective on how open educational resources can help to improve access, enhance quality and reduce the cost of education in the Global South. The project engaged a total of 103 researchers in 18 sub-projects across 21 countries from South America, Sub-Saharan Africa and Asia, coordinated by central Network Hub teams based at the University of Cape Town and Wawasan Open University.
This chapter forms part of a project activity toolkit, which is comprised of five documents outlining activities associated with each of the ROER4D UCT Network Hub pillars of project management activity: networking, evaluation, communications, research capacity development, and curation and dissemination. It is hoped that these chapters will be of practical use to other research projects attempting to integrate any of these functions in their operational strategy.
The chapter charts the experience of the ROER4D Communications Advisor in developing a research communication strategy for the project. It provides a short overview of the research communication field in order to give context and background to some of the field’s key debates and considerations, with attention given to the specific field of development research communication. Following this, it describes the evolution of the ROER4D research communication strategy.Citation: Walji, S. (2018). ROER4D project activity toolkit: Communications. Cape Town: Research on Open Educational Resources for Development. Retrieved from https://doi.org/10.5281/zenodo.122132
DS_10.1177_2380084419879387 – Supplemental material for Medical and Dental Electronic Health Record Reporting Discrepancies in Integrated Patient Care
No full textSupplemental material, DS_10.1177_2380084419879387 for Medical and Dental Electronic Health Record Reporting Discrepancies in Integrated Patient Care by S. Adibi, M. Li, N. Salazar, D. Seferovic, K. Kookal, J.N. Holland, M. Walji and M.C. Farach-Carson in JDR Clinical & Translational Research</p
Power modulation contrast enhanced ultrasound for postoperative perfusion monitoring following free tissue transfer in head and neck surgery
No full textThis feasibility study evaluated whether contrast enhanced ultrasound (CEU) was able to assess free flap perfusion following free tissue transfer in the head and neck region. Thirty-six patients underwent standard clinical monitoring (SCM) and CEU postoperatively. The time taken for each technique to detect flap failure was recorded. Qualitative CEU analysis by visual assessment predicted survival in 30/30 (100%) and failure in 5/6 (83%) flaps with sensitivity, specificity, positive (PPV) and negative (NPV) predictive values of 100, 86, 97 and 100%, respectively. Quantitative CEU measurement of blood volume (?) values within healthy perfused flaps was over 60 times higher than in failing flaps (8.25 ± 2.82 dB vs. 0.12 ± 0.17 dB, respectively, P < 0.0001). If a cut-off ? value of <1.5 dB was used to predict future flap failure, the accuracy of the test was 100% (sensitivity, specificity, PPV, NPV). If a cut-off ? value of >1.9 dB indicated flap success, the PPV and NPV are 100%. Following surgery, SCM took 76 (±15) h to detect flap failure compared with 18 (±38) h with CEU (P < 0.05). CEU is highly accurate in its ability to distinguish between perfused and failing flaps. The technique is quick (<10 min) and capable of imaging all flap types
DS_10.1177_2380084419892550 – Supplemental material for Finding Dental Harm to Patients through Electronic Health Record–Based Triggers
No full textSupplemental material, DS_10.1177_2380084419892550 for Finding Dental Harm to Patients through Electronic Health Record–Based Triggers by M.F. Walji, A. Yansane, N.B. Hebballi, A.M. Ibarra-Noriega, K.K. Kookal, S. Tungare, K. Kent, R. McPharlin, V. Delattre, E. Obadan-Udoh, O. Tokede, J. White and E. Kalenderian in JDR Clinical & Translational Research</p
The sandwich zygomatic osteotomy
No full textContains fulltext :
23198.PDF (Publisher’s version ) (Open Access
The role of incentive mechanisms in promoting forest restoration
No full textForest restoration has been proposed as a scalable nature-based solution to achieve global environmental and socio-economic outcomes and is central to many policy initiatives, such as the Bonn Challenge. Restored forests contain appreciable biodiversity, improve habitat connectivity and sequester carbon. Incentive mechanisms (e.g. payments for ecosystem services and allocation of management rights) have been a focus of forest restoration efforts for decades. Yet, there is still little understanding of their role in promoting restoration success. We conducted a systematic literature review to investigate how incentive mechanisms are used to promote forest restoration, outcomes, and the biophysical and socio-economic factors that influence implementation and program success. We found that socio-economic factors, such as governance, monitoring systems and the experience and beliefs of participants, dominate whether or not an incentive mechanism is successful. We found that approximately half of the studies report both positive ecological and socio-economic outcomes. However, reported adverse outcomes were more commonly socio-economic than ecological. Our results reveal that achieving forest restoration at a sufficient scale to meet international commitments will require stronger assessment and management of socio-economic factors that enable or constrain the success of incentive mechanisms. This article is part of the theme issue ‘Understanding forest landscape restoration: reinforcing scientific foundations for the UN Decade on Ecosystem Restoration’.Anazelia M. Tedesco, Pedro H. S. Brancalion, Michelle L. Hak Hepburn, Khalil Walji, Kerrie A. Wilson, Hugh P. Possingham, Angela J. Dean, Nick Nugent, Katerina Elias-Trostmann, Katharina-Victoria Perez-Hammerle, and Jonathan R. Rhode
Asymmetric Intermolecular C−H Activation, Using Immobilized Dirhodium Tetrakis((<i>S</i>)-<i>N</i>-(dodecylbenzenesulfonyl)- prolinate) as a Recoverable Catalyst
No full textHeterogenization of dirhodium tetrakis((S)-N-dodecylbenzenesulfonyl)prolinate) (Rh2(S-DOSP)4) can be readily achieved on a pyridine functionalized
highly cross-linked polystyrene resin. The immobilized complex is readily recycled and exhibits excellent catalytic activity for asymmetric
intermolecular C−H activation by means of rhodium carbenoid induced C−H insertion
A Systematic Correlation of Nanoparticle Size with Diffusivity through Biological Fluids
No full textNanomedicine, the application of nanotechnology for medical purposes, has been widely identified as a potential solution for today‟s healthcare problems. Nanomedicine uses the "bottom-up‟ principles of nanoscale engineering to improve areas of medicine which have previously been considered undevelopable.
One of the enduring challenges for medicine is the design of innovative devices able to overcome biological barriers, allowing drugs and therapeutics to effectively reach their correct location of action. Biological barriers are a defence mechanism of the body which are extremely well-evolved to protect the body from foreign and harmful particles. Therapeutic drugs and devices, which are not harmful, are often identified by the body as dangerous because their composition differs from native and accepted entities. The traversal of these biological barriers, such as mucus, remains a bottleneck in the progress of drug delivery and gene therapy. The mucus barrier physically limits the motion of particles due to its complicated mesh structure which obstructs the particles' traversal path. Mucus fibres can also adhere to the particles, entrapping them and restricting their motion.
Particle traversal of mucus is carried out by passive diffusion. As diffusion has traditionally been defined by the Stokes-Einstein equation as inversely proportional to particle radius, it follows that reducing particle sizes into the nanoscale would result in increased diffusive ability. These predictions, however, do not consider the obstructive effects of the complicated mesh structure for the case of mucus. The exact effect of reducing particle size into the nanoscale for diffusion through mucus is therefore unknown.
Multiple Particle Tracking was used to obtain real-time movies of the diffusion of nanoparticles, ranging from 12nm – 220nm in diameter, through mucus samples. The experimental data generated was used to systematically correlate the relationship between particle size and diffusivity through mucus. This study reveals that nanoparticles, smaller than the average pore size in the mucus mesh structure, can diffuse through lower viscosity pores which pose less resistance to diffusive motion, allowing nanoparticles to travel at up to four times the speed expected from the bulk viscosity of the mucus. This type of information can help researchers understand the importance of size for therapeutic nanoparticles, allowing researchers to decide whether attempts to decrease nanoparticle size at the expense of other functionality are worthwhile
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