1,721,067 research outputs found

    S(MeO)TLC overcomes Gemcitabine resistance.

    No full text
    <p>A: The IC50s of Gemcitabine in KU7、KU7-Gr、RT112 and RT112-Gr in 72 hours. B: The IC50s of S(MeO)TLC of KU7、KU7-Gr、RT112 and RT112-Gr in 72 hours. C: KU7-Gr and RT112-Gr cells were left untreated or were treated with 45nM Gemcitabine (GEM), 0.5μM S(MeO)TLC or both together (GEM+ S(MeO)TLC). Seventy-two hours later viability was analyzed by Trypan blue staining. S(MeO)TLC and GEM+ S(MeO)TLC, inhibiting tumor effect is the best among the four group. Quantification of each value is from triplicate independent experiments. (<i>p</i> < 0.01).</p

    S(MeO)TLC induces Gemcitabine resistance bladder cancer cells apoptosis.

    No full text
    <p>A: RT112-Gr cells were left untreated; B: RT112-Gr cells were treated with 45nM Gemcitabine; C: RT112-Gr cells were treated with 0.5μM S(MeO)TLC; D: RT112-Gr cells were treated with both together (45nM Gemcitabine + 0.5μM S(MeO)TLC) for the indicated times and then nuclear morphology was examined with Hoechst staining and visualized by fluorescent microscopy.</p

    Anticancer activity of S(MeO)TLC in subcutaneous xenograft tumors.

    No full text
    <p>A. After successful establishment of subcutaneous xenograft tumors, DMSO (vehicle control), 20 mg/kg S(MeO)TLC, 50 mg/kg Gemcitabine or both(S(MeO)TLC + GEM) were administered intraperitoneally daily for 5 days (arrows). Tumor volumes were measured every other day. B. The mean body weights of mice were assessed every other day. There is no significant difference among three groups (<i>P</i>>0.05).</p

    COMPARISON OF DIFFERENT CONTROL TECHNIQUES FOR ACTIVE FILTER APPLICATIONS

    No full text
    The paper presents a comparison among different current control techniques for active power filter. The fixed-frequency hysteresis controller, the predictive controller and the neural controller are considered and different performance, achieved by the three controls, in a typical active power filter application are shown and discussed. The paper presents a comparison among different current control techniques for active power filter. The fixed-frequency hysteresis controller, the predictive controller and the neural controller are considered and different performance, achieved by the three controls, in a typical active power filter application are shown and discussed. The paper presents a comparison among different current control techniques for active power filter. The fixed-frequency hysteresis controller, the predictive controller and the neural controller are considered and different performance, achieved by the three controls, in a typical active power filter application are shown and discussed. The paper presents a comparison among different current control techniques for active power filter. The fixed-frequency hysteresis controller, the predictive controller and the neural controller are considered and different performance, achieved by the three controls, in a typical active power filter application are shown and discussed

    PGSE diffusion NMR studies on mononuclear and dinuclear cationic platinum salts of (S)-MeO-Biphep and (R)-p-tolyl-BIN

    No full text
    PGSE diffusion NMR studies on a series of mononuclear and dinuclear cationic platinum salts derived from (S)-MeO-Biphep and (R)-p-tolyl-BINAP are reported. The data show that (a) one can readily distinguish between mononuclear and dinuclear cations (b) the amount of ion pairing can be estimated qualitatively and (c) the charge delocalization rather than the amount of formal charge per metal cation is important for the position of the anion. The solid-state structure of the chloro-bridged salt, [Pt(l-Cl){(S)-MeO-Biphep}] 2(CF3SO3)2, is reported

    Going Beyond Counting First Authors in Author Co-citation Analysis

    Full text link
    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
    corecore