6,089 research outputs found
Evaluation of the Failure Elongation of Steel Sheets for an Auto-body at the Intermediate Strain Rate
This paper deals with the dynamic failure elongation of mild steel, SGACD and advanced high strength steel sheets such as TRIP600, DP600 and TWIP steels. The failure elongation has been obtained from the high speed tensile testing machine with various strain rates ranged from 0.003/s to 200/s. The experimental result demonstrates that the tensile elongation does not simply decrease as the strain rate increases, but it decreases from the quasi-static state to the strain rate of 0.1 or 1/s and increases again up to the strain rate of 100/s. Furthermore, some high strength steels have the tendency that the tensile elongation increases as the strain rate increases. Moreover, the localized strain rate hardening in the necking region induces the increase of elongation
Evaluation of the failure elongation of steel sheets for an auto-body at the intermediate strain rate
This paper deals with the dynamic failure elongation of mild steel, SGACD and advanced high strength steel sheets such as TRIP600, DP600 and TWIP steels. The failure elongation has been obtained from the high speed tensile testing machine with various strain rates ranged from 0.003/s to 200/s. The experimental result demonstrates that the tensile elongation does not simply decrease as the strain rate increases, but it decreases from the quasi-static state to the strain rate of 0.1 or 1/s and increases again up to the strain rate of 100/s. Furthermore, some high strength steels have the tendency that the tensile elongation increases as the strain rate increases. Moreover, the localized strain rate hardening in the necking region induces the increase of elongation
Effects of Lewis number, density ratio and gravity on burning velocity and conditional statistics in stagnating turbulent premixed flames
DNS is performed to analyse the effects of Lewis number (Le), density ratio and gravity in stagnating turbulent premixed flames. The results show good agreement with those of Lee and Huh (Combustion and Flame, Vol. 159, 2012, pp. 1576-1591) with respect to the turbulent burning velocity, S-T, in terms of turbulent diffusivity, flamelet thickness, mean curvature and displacement speed at the leading edge. In all four stagnating flames studied, a mean tangential strain rate resulting in a mean flamelet thickness smaller than the unstretched laminar flame thickness leads to an increase in S-T. A flame cusp of positive curvature involves a superadiabatic burned gas temperature due to diffusive-thermal instability for an Le less than unity. Wrinkling tends to be suppressed at a larger density ratio, not enhanced by hydrodynamic instability, in the stagnating flow configuration. Turbulence is produced, resulting in highly anisotropic turbulence with heavier unburned gas accelerating through a flame brush by Rayleigh-Taylor instability. Results are also provided on brush thickness, flame surface density and conditional velocities in burned and unburned gas and on flame surfaces to represent the internal brush structures for all four test flames.X1122sciescopu
Neural Signals Related to Outcome Evaluation Are Stronger in CA1 than CA3
We have shown previously that CA1 conveys significant neural signals necessary to update value of the chosen target, namely chosen value and reward signals. To better understand hippocampal neural processes related to valuation, we compared chosen value- and reward-related neural activity between the CA3 and CA1 regions. Single units were recorded with tetrodes from the dorsal CA3 and CA1 regions of rats performing a dynamic foraging task, and chosen value- and reward-related neural activity was estimated using a reinforcement learning model and multiple regression analyses. Neural signals for chosen value and reward converged in both CA3 and CA1 when a trial outcome was revealed. However, these neural signals were stronger in CA1 than CA3. Consequently, neural signals for reward prediction error and updated chosen value were stronger in CA1 than CA3. Together with our previous finding that CA1 conveys stronger value signals than the subiculum, our results raise the possibility that CA1 might play a particularly important role among hippocampal subregions in evaluating experienced events. © 2017 Lee, Huh, Lee, Ghim, Lee and Jung. © 2017 Lee, Huh, Lee, Ghim, Lee and Jung. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. Copyright © 2017 Lee, Huh, Lee, Ghim, Lee and Jung. This is an open-access article
distributed under the terms of the Creative Commons Attribution License (CC BY).
The use, distribution or reproduction in other forums is permitted, provided the
original author(s) or licensor are credited and that the original publication in this
journal is cited, in accordance with accepted academic practice. No use, distribution
or reproduction is permitted which does not comply with these terms.1221Nsciescopu
Identification of a Calcium Signalling Pathway of S-[6]-Gingerol in HuH-7 Cells
Calcium signals in hepatocytes control cell growth, proliferation, and death. Members of the transient receptor potential (TRP) cation channel superfamily are candidate calcium influx channels. NF?B activation strictly depends on calcium influx and often induces antiapoptotic genes favouring cell survival. Previously, we reported that S-[6]-gingerol is an efficacious agonist of the transient receptor potential cation channel subfamily V member 1 (TRPV1) in neurones. In this study, we tested the effect of S-[6]-gingerol on HuH-7 cells using the Fluo-4 calcium assay, RT-qPCR, transient cell transfection, and luciferase measurements. We found that S-[6]-gingerol induced a transient rise in in HuH-7 cells. The increase in induced by S-[6]-gingerol was abolished by preincubation with EGTA and was also inhibited by the TRPV1 channel antagonist capsazepine. Expression of TRPV1 in HuH-7 cells was confirmed by mRNA analysis as well as a test for increase of by TRPV1 agonist capsaicin and its inhibition by capsazepine. We found that S-[6]-gingerol induced rapid NF?B activation through TRPV1 in HuH-7 cells. Furthermore, S-[6]-gingerol-induced NF?B activation was dependent on the calcium gradient and TRPV1. The rapid NF?B activation by S-[6]-gingerol was associated with an increase in mRNA levels of NF-B-target genes: cIAP-2, XIAP, and Bcl-2 that encode antiapoptotic proteins
Estimation of atmospheric CO <sub>2</sub> uptake by silicate weathering in the Himalayas and the Tibetan Plateau: a review of existing fluvial geochemical data
The fluvial geochemical data of major rivers draining the Himalayas and the Tibetan Plateau (HTP) are compiled from literature and supplemented with data from the author's group to explore the spatial variability in the major element and strontium isotopic compositions and in rates of silicate weathering and concomitant drawdown of atmospheric CO2. The results indicate that carbonate weathering dominates the major element composition of these rivers, and when the silicate contributions are carefully separated, there is spatial variability within the HTP system. Silicate contributions are highest in the rivers of the Himalayan syntaxes and in the Yamuna, Alaknanda-Bhaghirathi and Kosi tributaries of the Ganges. The 87Sr/86Sr ratios are especially radiogenic in the Ganges tributaries but the values do not necessarily correlate with the relative input from silicate weathering. Even in the Yamuna tributary of the Ganges where rates of CO2 consumption by silicate weathering are several times those of the rivers of the eastern Tibetan Plateau, the rates are comparable to the rivers draining the Andes. Thus, the Ganges tributaries supply uniquely radiogenic 87Sr to the ocean but cannot be considered anomalous in terms of silicate weathering rates in comparison to other major rivers draining orogenic zones. © The Geological Society of London 2010.N
Data and code for: Huh et al. (2021). A structural equation modeling approach to meta-analytic mediation analysis using individual participant data
This data repository contains the companion R code and data set for: Huh, D., Li, X., Zhou, Z., Walters, S. T., Baldwin, S. A., Tan, Z., Larimer, M. E., & Mun, E.-Y. (2021). A structural equation modeling approach to meta-analytic mediation analysis using individual participant data: Testing protective behavioral strategies as a mediator of brief motivational intervention effects on alcohol-related problems. Prevention Science. https://doi.org/10.1007/s11121-021-01318-
Frog went a'courtin and he did ride....Uh-Huh!
voiceCollected by Ron Smith, Chester Lowe, and Tom Harper.
For M. C. Parler Transcribed by Ron R. Smith,
Chester Lowe, and Tom Harper.
Sung by
Mrs. R.S. Remy Booneville, Ark. Janurary 9, 1960
Reel 340, Item 1
FROG WENT A'COURTIN
Frog went a'courtin and he did ride....Uh-Huh!
Frog went a'courtin and he did fide
A sword and pistol by his side.....Uh-Huh!
He rode up to Miss Mousies' gate...Uh-Huh!
He rode up to Miss Mousies' gate
Miss Mouse was waiting for the gallant-came-late...Uh-Huh!
He took little Mousie upon his knee...Uh-Huh!
He took little Mousie upon his knee
And said Little domic will you marry me...Uh-Huh!
Where shall our wedding supper be...Uh-Huh!
Where shall our wedding supper be
Way down yonder in the hollow tree...Uh-Huh!
Frog started home by the side of the brook...Uh-Huh!
Frog started home by the side of the brook
One foot slipped and he fell hooked...Uh-Huh!
What shall the wedding supper be...Uh-Huh!
What shall the wedding supper be
A great big bean and a black-eyed pea...Uh-Huh!Funding for digitization provided by the Arkansas Humanities Council and the Happy Hollow Foundation
Numerical Simulation of Rectangular Cup Drawing Processes with Drawbeads
5th NUMIFORM '95, in Ithaca, New York, U.S.A., 1995.Rectangular cup drawing processes are numerically simulated by a modified membrane finite element method. The simulation examines the effect of drawbeads on the deep drawing process. The numerical result demonstrates that drawbeads control the amount of drawing from the flange region into the die cavity and the strain distribution of the deep drawn cup
Conditional moment closure modeling of turbulent nonpremixed combustion in diluted hot coflow
The conditional moment closure (CMC) model is applied to predict flame structures and NO formation in the moderate and intense low oxygen dilution combustion mode. The effects of oxygen concentration in a hot diluted oxidant stream are investigated in the experimental condition of Dally et al. [Proc. Combust. Inst. 29 (2002) 1147–1154]. The GRI 2.11 Mech is used for description of chemical reaction including NOx chemistry. The conditional scalar dissipation rate, which describes the effect of turbulent mixing on finite chemistry, is calculated by integrating the transport equation for probability density function (PDF). A new PDF is proposed to describe three stream mixing in terms of a single mixture fraction. The conditional mean predictions of temperature, and CO, OH, and NO mass fractions are in good agreement with measurements. The unconditional Favre mean predictions of CO and NO mass fractions are also in reasonable agreement. Upstream underprediction of OH and NO in the low oxygen concentration case may be attributed to uncertainty in low temperature reaction mechanism and mixing prediction. Differential diffusion effects are shown to be nonnegligible in the present flames. The CMC model is an attractive choice for simulation of MILD combustion in which conditional fluctuations of reactive scalars are small enough for first-order closure of conditional mean reaction rates to remain valid.Seung Hyun Kim, Kang Y. Huh, and Bassam Dallyhttp://www.elsevier.com/wps/find/journaldescription.cws_home/703522/description#descriptio
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