1,721,391 research outputs found

    Captain Don. S. Gentile

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    Black and white photograph showing American pilot, Captain Don. S. Gentile taking off in his P-51 Mustang bomber from an English base

    Booklet re: Don S. Gentile and John T. Godfrey

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    Booklet re: the history of two fighter pilots, Don S. Gentile and John T. Godfrey, and how they ended up in Fort Worth, Texa

    A TPQ interview: John S. Gentile Talks with Lou Burton

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    The National Endowment for the Humanities and state humanities councils have funded projects which revive and adapt the old tent Chautauqua concept of bringing education and entertainment to America\u27s heartland. In this TPQ interview, John S. Gentile talks with Lou Burton, the project director for the highly successful Rocky Mountain Chautauqua, who discusses the challenges, problems, and rewards of teaching history through performance in public humanities projects

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    THE PROTECTIVE ROLE OF PTX3 IN MOUSE SKIN CARCINOGENESIS

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    Abstract The implication of the innate immune system on inflammatory carcinogenesis is a central topic in tumor biology. The humoral pattern recognition molecule PTX3 plays a fundamental role in the modulation of inflammation by regulating Complement cascade and P-selectin dependent neutrophil recruitment. Available information in human and murine 3-MCA induced sarcomas suggests a protective role of PTX3 in cancer-related inflammation. In this study we showed that PTX3-deficient mice were more susceptible to DMBA/TPA chemically-induced epithelial skin cancer than PTX3-competent mice, in term of incidence, multiplicity of papillomas and number of lesions evolving to skin carcinomas, suggesting a more aggressive behavior of PTX3-/- tumors. In the skin, PTX3 was strongly produced during the acute phase of carcinogenesis by infiltrating macrophages, neutrophils, and vessels. Immunohistochemical investigation of papillomas showed low presence of PTX3 in the extracellular matrix. The deficiency of PTX3 was associated with increased cancer-related inflammation in term of neutrophil infiltration, higher production of pro-inflammatory cytokines and chemokines, increased C3 and IgG deposition. In the effort to define the molecular mechanisms underlying this phenotype, we observed that P-selectin deficiency and in vivo neutrophil depletion reverted the tumor susceptibility of Ptx3-/- mice. All together, these results provide evidence that PTX3 is locally produced and plays a protective role in epithelial skin carcinogenesis acting as an extrinsic oncosuppressor. The mechanism of PTX3-mediated protection is explained by modulation of cancer-related inflammation regulating P-selectin dependent neutrophil recruitment and Complement activation

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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