74 research outputs found
Response to: RE: Long-term outcomes and risk factors for failure with the EX-press glaucoma drainage device
No full textMorphométrie géométrique et classification phylogénétique, application à la question de l’origine d’Homo sapiens en Asie
No full textInternational audienceThe objective of this study was to find out whether or not there is a morphological gap between the fossils living in the last million years discovered in Asia. The geometric morphometric methods were applied to the skulls of 18 specimen Asian fossils dated 6,000 to 1,150,000 years. Landmarks were analyzed by Generalized Procrustes Analysis. Principal component analysis (PCA) and hierarchical classification methods (UPGMA and NJ) were applied to those samples in order to identify homogenous subgroups. The Mahalanobis distances between those subgroups have been calculated. Two phylogenetic analyses have been applied to the quantitative characters: the maximum likelihood approach and a cladistic analysis. A sample of gorilla and chimpanzees was used as the out-group. Classification and PCA analysis identified 2 subgroups in the fossil group: one with an Homo sapiens affinity and the other with an Homo erectus affinity. Both phylogenetic analyses identified Homo erectus as a monophyletic subgroup, but the fossil subgroup with an Homo sapiens affinity are scattered among the extant Homo sapiens. We finally concluded that the fossils belong to 2 different taxa. The first (fossil Homo sapiens) belong to the same taxon than extant Homo sapiens, and the second is attributed to Homo erectus.Ce travail porte sur la continuité ou la rupture des fossiles, datant du dernier million d’années, retrouvés en Asie du Sud-Est. Les méthodes de morphométrie géométrique ont été appliquées aux crânes de 18 spécimens fossiles asiatiques datés de 6 000 à 1 150 000 ans. Les coordonnées de points repères ont été analysées avec la méthode GPA (generalized procrustes analysis). Des analyses de classification (UPGMA et NJ) et une analyse en composantes principales ont été utilisées afin d’identifier d’éventuels sous-groupes dans cet échantillon. Les distances de Mahalanobis entre ces sous-groupes ont été calculées.Deuxméthodes d’analyse phylogénétique ont été appliquées aux variables quantitatives: la méthode du maximum de vraisemblance et une analyse cladistique. Un échantillon de chimpanzés et de gorilles constituent les extragroupes. Les méthodes de classifications ont identifié deux groupes au sein de l’échantillon des fossiles: un groupe d’affinité Homo erectus et un autre d’affinité Homo sapiens. Les analyses phylogénétiques réalisées identifient le groupe Homo erectus comme étant monophylétique. En revanche, les individus du groupe fossile d’affinité Homo sapiens se retrouvent dispersés avec les hommes actuels. On peut donc en conclure que les fossiles étudiés appartiennent à deux taxons différents. Le premier (Homo sapiens fossiles) peut être considéré comme appartenant au même taxon que celui des hommes actuels. Le second appartient à un taxon différent
PCN26 RELATIVE IMPACT OF SCREENING AND THERAPEUTIC PROGRESS ON THE REDUCTION OF BREAST CANCER SPECIFIC MORTALITY IN FRANCE: A SIMULATION MODEL OVER THE PERIOD 1994–2005
No full textNon-standard synoptic hour observations from fixed land stations _ BOUEE MEDIT 61001
No full text---- The bulletin collects SHIP reports:
FM 13 (SHIP, Report of surface observation from a sea station).
(Refer to WMO No.306 - Manual on Codes for the definition of WMO international codes)
---- The SNVF41 TTAAii Data Designators decode (2) as:
T1 (S): Surface data.
T2 (N): Non-standard synoptic hour.
A1 (V): Mobile ships and other marine stations.
A2 (F): Area between 90°N - 30°N, 035°W - 070°E.
(2: Refer to WMO No.386 - Manual on the GTS - Attachment II.5
PCV118 Observational Study on the Treatment, Cost and Quality of Life of Subjects with Hereditary Angioedema
No full textPCV26 Real World Incidences And Hospital Cost Of Venous And Pulmonary Thromboembolic Events In France
No full textO trinômio mãe-pai-filho como foco central da assitência de enfermagem : uma experiência fundamentada na teoria das necessidades humanas básicas
No full textA real-life study of the use, effectiveness and tolerability of rosiglitazone in France : The AVANCE study
No full textAim. - The study aimed to determine the effectiveness and tolerability of rosiglitazone, and its profile in terms of treatment adherence, treated patients and prescribing recommendations under everyday conditions of care. Methods. - This was a "real-life" observational longitudinal study including patients with type 2 diabetes mellitus (T2DM) starting treatment with rosiglitazone and followed for up to 2 years. A questionnaire was completed at the time of inclusion and during routine consultations at around 6, 12, 18 and 24 months following inclusion. Information was collected on sociodemographics, clinical history, treatments, co-morbidities, laboratory data and compliance with treatment. There were three primary outcome measures: treatment response (defined as an HbA(1c) = 0.7%); switch to insulin (as considered necessary by the physician); and occurrence of adverse events requiring a change or discontinuation of treatment. Results. - The evaluation included 670 patients (61.1%) treated with rosiglitazone/metformin as fixed-dose combination tablets and 427 (38.9%) with standard rosiglitazone tablets. Rates of HbA(1c) response, defined as an HbA(1c) less than or equal to 8.0% or a decrease in HbA(1c) greater than or equal to 0.7%, ranged from 80.6% to 92.1% depending on the follow-up time. The percentage of patients with an HbA(1c) less than 7% was 18.4% before rosiglitazone was prescribed, and ranged from 48.2% to 57.8% depending on the follow-up period. Sixty-two patients (6.1%, 95% CI: 4.6-7.6%) switched to insulin therapy during the follow-up period. Spontaneously reported adverse events leading to a change or discontinuation of treatment were seen in 45 patients (4.4%, 95% CI: 3.2-5.6%). Conclusion. - Rosiglitazone showed sustained efficacy, with around 90% of patients defined as responders to the treatment in terms of reduction in HbA(1c), and was relatively well tolerated. The adverse-event profile was consistent with the known effects of rosiglitazone, and no signs of increased cardiovascular ischaemic risk were observed. These results are in agreement with previous studies on rosiglitazone
QL7 PREVALENCE AND QUALITY OF LIFE OF PATIENTS SUFFERING FROM RESTLESS LEGS SYNDROME IN FRANCE—INSTANT STUDY
No full textPCV26 – Real World Incidences And Hospital Cost Of Venous And Pulmonary Thromboembolic Events In France
No full textTo estimate the cumulative incidence and hospital cost for venous and pulmonary thromboembolic events in a real world setting in France.nonnonrechercheInternationa
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