283 research outputs found
Supplemental Material for Goetsch and Strome, 2022
No full textSupplemental information includes supplemental
Materials and Methods. Figure S1 contains full western blots presented in
Figure 2D. Figure S2 contains full western blots presented in Figure 3B. Figure
S3 contains additional DREAM target genes tested using qPCR for ChIP and
sequential ChIP analyses to complement Figure 6. Antibodies used for western
blot and ChIP analyses are available in Supplemental Table S1. Primers used for
cloning and qPCR are available in Supplemental Table S2. DESeq2 differential
gene expression analysis data are available in Supplemental Table S
The Job of Being Everybody
No full textDouglas Goetsch’s books of poetry include Nobody’s Hell (Hanging Loose Press, 1999), The Job of Being Everybody (Cleveland State University Poetry Center, 2004, winner of the CSU Poetry Center Open Competition), Nameless Boy (forthcoming), and four chapbooks. He is a recipient of fellowships from the National Endowment for the Arts and the New York Foundation for the Arts, a Pushcart Prize, the Donald Murray Prize, the Paumanok Prize, and numerous other honors. His work has appeared in Poetry, The New Yorker, The Iowa Review, The Gettysburg Review, Best American Poetry, online at Garrison Keillor’s The Writer’s Almanac, and on the air at NPR.
“Douglas Goetsch is, without a doubt, an unbridled creative talent. His pinpoint lyricism and apparent reverence for craft stamp his work with a gorgeous signature, and he just gets better with every outing. These are poems of desire and disappointment, the magnificent and the mundane—and in Goetsch’s capable clutches, each one leaves an electric charge in the air. This is no misty-eyed look at where poetry has been or where it’ s going. The Job of Being Everybody is where poetry should be, where it should have been all along.” –Patricia Smith
“The gritty naturalism of these poems would qualify them as ‘anti-lyrical’ were it not for the mix of sweet nostalgia and bitter truth that gives them their pungent, winning flavor. It’s hard to imagine a reader who could resist Goetsch’s seductive opening lines.” –Billy Collins
“Douglas Goetsch’s autobiographical poetry is so consistently bleak, I’m not quite sure why I so often find it moving. I guess partly because the poetry seems so free from baloney, and because there is a sweetness down inside Goetsch’s insistence on the factual.” –Mark Halliday
More Information:
Douglas Goetsch Website
Poetry Dailyhttps://engagedscholarship.csuohio.edu/clpc_bks/1043/thumbnail.jp
Tie Makers at Camp
No full textPhotograph - A group standing in the snow in front of a log cabin, Pelican Portage, Alberta. Left to right: unknown, unknown, Elsie Goetsch, Bruno Goetsch, unknown and Joe Laflamm
Sox15 and Fhl3 transcriptionally coactivate Foxk1 and regulate myogenic progenitor cells
No full textThe regulation of myogenic progenitor cells during muscle regeneration is not clearly understood. We have previously shown that the Foxk1 gene, a member of the forkhead/winged helix family of transcription factors, is expressed in myogenic progenitor cells in adult skeletal muscle. In the present study, we utilize transgenic technology and demonstrate that the 4.6 kb upstream fragment of the Foxk1 gene directs beta-galactosidase expression to the myogenic progenitor cell population. We further establish that Sox15 directs Foxk1 expression to the myogenic progenitor cell population, as it binds to an evolutionarily conserved site and recruits Fhl3 to transcriptionally coactivate Foxk1 gene expression. Knockdown of endogenous Sox15 results in perturbed cell cycle kinetics and decreased Foxk1 expression. Furthermore, Sox15 mutant mice display perturbed skeletal muscle regeneration, due in part to decreased numbers of satellite cells and decreased Foxk1 expression. These studies demonstrate that Sox15, Fhl3 and Foxk1 function to coordinately regulate the myogenic progenitor cell population and skeletal muscle regeneration.NIAMS NIH HHS [AR 47850, R01 AR047850
Determining hydrogen peroxide exposure of employees at Company XYZ
Get PDFPlan BThe significance of this study stems from the plethora of health effects associated with the exposure of industrial hydrogen peroxide concentrations. An extensive literature review established the serious health effects resulting from both acute and chronic hydrogen peroxide exposure. Monitoring was performed using Draeger-Tubes® and a Pac III measuring device. Previous Draeger-Tube® and time weighted average data was also obtained to help make informed conclusions. Results lead the researcher to conclude that employees at Company XYZ are being overexposed to hydrogen peroxide only during the start-up stage when the equipment is being sterilized. Several control options are recommended for consideration, each having benefits as well as concerns. Engineering controls are preferred, but respiratory protection usage is practical under the circumstances. The study found that the threat of hydrogen peroxide overexposure is in fact true at certain operational stages and that such exposure may lead to serious health effects in future
[MI.269] Goetsch-Winckler Residence
No full texthttps://nsuworks.nova.edu/nsudigital_flwimages/2070/thumbnail.jp
Karl Heinz Göller, Gerhard Hoffmann, Hrsg., Die amerikanische Kurzgeschichte, August Bagel Verlag, Düsseldorf 1972, 429 S.
No full textAn occupational survey to determine the entry level CAD skills and competencies required by employers of civil engineering technicians in the Northeast Wisconsin Technical College district
Get PDFIncludes bibliographical references.The purpose of this study was to identify the CAD related technical skills and
competencies that are required for employability at an entry-level position as a civil engineering technician. The majority of employers represented in this study are civil engineering firms, governmental agencies, and surveying firms. Overall, civil engineering firms along with governmental agencies employ the greatest number of drafters. Civil drawings, survey maps, and topographical drawings are the most commonly prepared drawings by the respondents. Other reported drawing types include architectural, electrical/electronic, landscaping, structural, and technical illustrations. Almost all of the respondents use a CAD system for drafting functions. AutoCAD is
the primary CAD platform used. MicroStation is also used, but to a much lesser extent. Of the employers that use CAD software, most use at least one collaborative software package with their primary CAD platform. Eagle Point is the most common collaborative software utilized. AutoCAD Land Development Desktop (ALDD) was noted to be the next commonly used collaborative software. Out of the 24 basic CAD skills that were listed on the survey, 14 were considered to be valid curriculum items and will be either retained or added to the program curriculum. Six of the 24 items will be reviewed for being valid curriculum items, and four of the items will not be included in the curriculum. Overall, most basic CAD skills were performed frequently or considered important. Out of the 29 advanced CAD skills that were listed on the survey, none were considered to be valid curriculum items. Sixteen of the 29 items will be reviewed for being valid curriculum items, and 13 of the items will not be included in the curriculum. Overall, most advanced CAD skills were not performed frequently nor considered important. Out of the 15 basic architectural drawing skills that were listed on the survey, none were considered to be valid curriculum items. Eight of the 15 items will be reviewed for being valid curriculum items, and seven of the items will not be included in the curriculum. Overall, most basic architectural drawing skills were not performed frequently nor considered important. None of the six basic structural drawing skills that were listed on the survey were considered to be valid curriculum items. One of the six items will be reviewed for being a valid curriculum item, and five of the items will not be included in the curriculum. Overall, most basic structural drawing skills were not performed frequently nor considered important
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