139 research outputs found
Reno productive activity of Ipomoea digitata in gentamicin induced kidney dysfunction
No full textKidneys endowed with million units termed as “nephrons†that act as natural sieves. The kidneys provide the final common pathway for the excretion of many drugs and their metabolites and therefore are frequently subjected to high concentrations of potentially toxic substances. Administration of several antibiotics like Gentamicin causes kidney dysfunction. Rats treated with Gentamicin developed significant kidney dysfunction was observed from increased level of urea, creatinine, sodium and decreased level of protein, potassium and non enzymatic antioxidants such as vitamin C and vitamin E. The plant, Ipomoea digitata is found to have nephroprotective activity. --------------------------------------------------------------------------------------------------------*Department of Biochemistry and Chemistry, Faculty of Science, PRIST University, Vallam, Tanjavur – 613 403, Tamilnadu, India**Department of Zoology, Annamalai University, Annamalainagar - 608 002, Tamilnadu, India1Corresponding author, Email: [email protected] This Article As: A. Kalaiselvan, T. Anand and M. Soundararajan.Reno productive activity of Ipomoea digitata in gentamicin induced kidney dysfunction. J. Ecobiotechnol. 2(2): 57-62
A retrospective study of clinical profile and outcomes of critically ill patients with heat-related illness
No full textBackground and Aims: Heat-related illness (HRI) due to high ambient temperatures is a common feature during the Indian summer. HRI often results in Intensive Care Unit (ICU) admissions and are associated with significant morbidity and mortality. However, published report on the effects of HRI among the Indian population is lacking. This study was undertaken to identify the profile of patients admitted to ICU with clinical features of HRI and study their clinical outcomes. Methods: This was a retrospective case series of patients admitted with features of HRI during the summer of 2012 in our multidisciplinary ICU. Data on demographics, co-morbid illness, admission severity of illness (Acute Physiology and Chronic Health Evaluation II [APACHE II]), organ failure scores (Sequential Organ Failure Assessment [SOFA]) and neuroimaging studies were collected. Outcome data studied included mortality, ICU length of stay (LOS), ventilator days and hospital LOS. Statistical analysis was performed using Student′s t-test, Chi-square test and multivariate analysis. Results: Twenty-six patients met the diagnostic criteria for HRI. Fifteen were males. The mean age was 53.12 18.6 years. Mean APACHE II score was 19.6 7.7 and mean SOFA score was 7.5 2.6. The common presenting symptoms were fever with neurological impairment (100%) and gastrointestinal symptoms (30%). Major organ systems involvement include neurological (100%), renal (57%), hepatic (34%) and coagulation abnormalities (26%). Most common metabolic abnormality noted was hyponatraemia (73%). Magnetic resonance imaging findings suggestive of heat stroke were seen in 5 of 26 patients. Mortality rate was 34%. 8 of 17 survivors had residual neurological impairment. Conclusion: HRI carries a high mortality and significant neurological morbidity
”Evaluation of safety margin” in ameloblastoma of the mandible by surgical, radiological, and histopathological methods: An evidence-based study
No full textObjective: The purpose of this study is to elicit the amount of safety margin necessary around the ameloblastic lesion in view of preventing further recurrence. Materials and Methods: The study consisted of 25 cases of mandibular ameloblastoma. Diagnosis was based on clinical and radiological analysis and confirmed by histopathological report. An incisional biopsy was done preoperatively to confirm the diagnosis. Segmental resection was planned for all the cases. After the resection, postoperative panoramic radiograph of the specimen was taken followed by histopathological examination of its margin to detect tumor cell infiltration. Results and Conclusion: In all our cases, the ameloblastoma was infiltrating in nature. A follow-up period of 10 years showed neither recurrence nor implant failure. In our study, we conclude our safe margin for infiltrating variant of ameloblastoma based on histopathological report of the resected specimen
Tamil Food and Medical Ideas
No full textIt is the need of the hour to study and bring out the food habits of the people found in the books written in Tamil literature from ancient times to medieval periods, Bhakti periods, later periods and modern times, the types of food they are eaten, their benefits and the natural medicinal tips of the people. Accordingly, the references to the literature written during the Sangam period which can be traced back to Tamil literary texts are explained. Moreover, as far as later literature is concerned, whether it is medicine or diet, the highest among them is the study of the literature of the 18 Siddhars starting from Agastya who can do siddhu work
Propagation of shear wave in a non-homogeneous thinly layered laminated medium under magnetic field with couple stress
No full textIntuitionistic fuzzy MAUT-BW Delphi method for medication service robot selection during COVID-19
No full textCoronavirus Disease 2019 (COVID-19), a new illness caused by a novel coronavirus, a member of the corona family of viruses, is currently posing a threat to all people, and it has become a significant challenge for healthcare organizations. Robotics are used among other strategies, to lower COVID’s fatality and spread rates globally. The robot resembles the human body in shape and is a programmable mechanical device. As COVID is a highly contagious disease, the treatment for the critical stage COVID patients is decided to regulate through medication service robots (MSR). The use of service robots diminishes the spread of infection and human error and prevents frontline healthcare workers from exposing themselves to direct contact with the COVID illness. The selection of the most appropriate robot among different alternatives may be complex. So, there is a need for some mathematical tools for proper selection. Therefore, this study design the MAUT-BW Delphi method to analyze the selection of MSR for treating COVID patients using integrated fuzzy MCDM methods, and these alternatives are ranked by influencing criteria. The trapezoidal intuitionistic fuzzy numbers are beneficial and efficient for expressing vague information and are defuzzified using a novel algorithm called converting trapezoidal intuitionistic fuzzy numbers into crisp scores (CTrIFCS). The most suitable criteria are selected through the fuzzy Delphi method (FDM), and the selected criteria are weighted using the simplified best–worst method (SBWM). The performance between the alternatives and criteria is scrutinized under the multi-attribute utility theory (MAUT) method. Moreover, to assess the effectiveness of the proposed method, sensitivity and comparative analyses are conducted with the existing defuzzification techniques and distance measures. This study also adopt the idea of a correlation test to compare the performance of different defuzzification methods
A Case Study on Settlement of Oil Storage Tank Foundations
No full textFoundations of 8 Steel Oil storage tanks and two fire water tanks were proportioned limiting total settlement to 100 mm. The soil at the site consists of alternating layers of cohesive and cohesionless soils. Settlement estimates were based on currently available methods with suitable modifications to the situation met with. The tanks were load tested (Hydrotest) and settlements observed at nine locations along the periphery on tank shell base. These observed settlements are compared with the estimated values
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