1,720,962 research outputs found
Kualitas Kepemimpinan Pendidikan dalam Konteks Organisasi Pembangunan Sumber Daya Manusia
Kepemimpinan memainkan peranan kunci dalam melaksanakan dasar pendidikan dan bertanggung jawab untuk meletakkan sebagian besar dasar yang berlaku di sekolah-sekolah. Beberapa kriteria kualitas kepemimpinan yang baik antara lain, memiliki komitmen organisasional yang kuat, visionary, disiplin diri yang tinggi, antusias, berwawasan luas, kemampuan komunikasi yang tinggi, manajemen waktu, mampu menangani setiap tekanan, mampu sebagai pendidik bagi bawahannya, empati, berpikir positif, memiliki dasar spiritual yang kuat, dan selalu siap melayani. Pengelolaan yang efektif membutuhkan sound system pembangunan sumber daya manusia sehingga organisasi harus memiliki sumber daya manusia yang efektif. Agar organisasi pendidikan itu berhasil diperlukan pemimpin yang berkemampuan kualitas, tangguh, dan mumpuni
Pengaruh Penyelenggaraan Sekolah Tinggi Keguruan dan Ilmu Pendidikan Muhammadiyah Sorong dan Manajemen Berbasis Sekolah terhadap Keberhasilan Otonomi Daerah Bidang Pendidikan di Kabupaten Sorong
Penelitian ini bertujuan untuk mengetahui seberapa besar pengaruh antara penyelenggaraan Sekolah Tinggi Keguruan dan Ilmu Pendidikan Muhammadiyah Sorong terhadap Keberhasilan Otonomi Daerah Bidang Pendidikan di Kabupaten Sorong Metode yang digunakan dalam penelitian ini adalah deskriptif analitik. Populasi yang diamati adalah kalangan civitas akademika STKIP Muhammadiyah Sorong, kepala sekolah dan guru , tokoh masyarakat, dan birokrat, semua dari kabupaten Sorong. Sampel diambil dengan teknik Stratified Random Sampling sejumlah 40 orang. Analisisnya menggunakan korelasi dan regresi sedang teknik pengumpulan data dengan menggunakan penyebaran kuesioner, observasi, dokumentasi, dan studi kepustakaan data dilakukan secara kuantitatif melalui tabel frekuensi. Dari hasil penelitian diperoleh, Pertama, terdapat pengaruh yang signifikan antara Penyelenggaraan STKIP Muhammadiyah Sorong terhadap Keberhasilan Bidang Pendidikan di Kabupaten Sorong. Kedua, terdapat pengaruh yang signifikan antara MBS terhadap Keberhasilan OTDA Bidang Pendidikan di Kabupaten Sorong. Ketiga, terdapat pengaruh yang signifikan antara Penyelenggaraan STKIP Muhammadiyah Sorong dan MBS secara bersama-sama terhadap keberhasilan OTDA Bidang Pendidikan di Kabupaten Soron
Pengetahuan Mengenai Antibiotika di Kalangan Mahasiswa Ilmu – Ilmu Kesehatan Universitas Gadjah Mada YOGYAKARTA
Inappropriate use of antibiotics, both prescribed and non-prescribed, is a global public health problem. In Indonesia, there is an increase of self-medication with antibiotics in the community in the last decade. Health practitioners are the main source of information and advice on self-medication with antibiotics in the community. Therefore, it is important to investigate knowledge of antibiotics among students of health sciences because they are candidates for future health practitioners. This study is an observational cross-sectional survey using a validated questionnaire. Respondents were 150 students of health sciences faculties at Gadjah Mada University Yogyakarta who were selected using a non-random convenience sampling technique. Of the 150 respondents, 79%(119) were familiar with antibiotics. Only these data (n =119) were subsequently analysed. Overall, they had appropriate knowledge about efficacy of antibiotics for bacterial infections and risks of antibiotic use, i.e. allergic reactions and antibiotic resistance. However, their knowledge about efficacy of antibiotics for viral infections and the use of antibiotics immediately for fever were not appropriate. In general, 34% of respondents had high level of knowledge about antibiotics, 54% in the moderate level and 12% in the low level
Analisis Kombinasi Preloading Mekanis dan Elektrokinetik terhadap Pemampatan Tanah Lunak Pontianak
Daya dukung tanah yang rendah dan besarnya penurunan yang dapat terjadi pada tanah lunakdipengaruhi oleh tingginya kandungan air di dalamanya. Metode Elektroosmotik merupakan salah satu metode yang dapat digunakan untuk mengurangi kadar air yang ada pada tanah lunak, dengan cara menempatkan katoda dan anoda yang dialiri listrik ke dalam tanah dalam satu jarak tertentu, sehingga air akan mengalir dari anoda (+) ke katoda (-) sebagai manivestasi gejala elektroosmosis.Pada penelitian ini dilakukan uji konsolidasi dengan matriks percobaan yang berbeda-beda.Hasil uji laboratorium pada pengujian konsolidasi dengan preloading 144 jam dikombinasikan dengan arus 15 mA menunjukkan adanya penurunan pada nilai indeks pemampatan sebesar 37.16% efisiensi waktu sebesar 18.18% dan pada pengujian konsolidasi dengan preloading 144 jam dikombinasikan dengan arus 30 mA penurunan nilai indeks pemampatannya sebesar 42.66% efisiensi waktu sebesar 36.36%. Hasil tersebut menunjukkan bahwa akibat pengaruh listrik,kekakuan tanah dapat meningkat dan proses pemampatan tanah yang terjadi dapat dipercepat
KORELASI BATAS CAIR DAN INDEKS PLASTISITAS TERHADAP NILAI KOHESI TANAH PADA UJI TRIAXIAL UU (UNCONSOLIDATED-UNDRAINED) TANAH LEMPUNG PADA KABUPATEN MEMPAWAH
Tanah lempung merupakan tanah kohesif yang memiliki sifat-sifat plastis pada tanah. Tujuan penelitian ini untuk mengetahui korelasi batas cair (LL) dan indeks plastisitas (IP) terhadap nilai kohesi tanah lempung di Kabupaten Mempawah. Dalam penelitian ini, pengujian dilakukan dengan menggunakan Triaxial UU (unconsolidated -undrained). Sampel tanah yang akan digunakan adalah jenis tanah lempung yang berada di Kabupaten Mempawah. Sistem klasifikasi tanah mengunakan AASHTO, USCS dan USDA, semua sampel tanah yang digunakan memiliki fraksi lempung. Hasil data yang dianalisa menggunakan analisa regresi dan korelasi menghasilkan persamaan (c = 0,0003(LL) + 0,0345 dengan r² = 0,01) dan (c = 0,0007(IP) + 0,0304 dengan r² = 0,216). Pada uji hipotesa menunjukkan bahwa terdapat pengaruh yang signifkan antara nilai batas cair (LL) dan indeks plastisitas (IP) terhadap nilai kohesi (c) tanah lempung di Kabupaten Mempawah. Penelitian ini membuktikan bahwa semakin besar nilai batas cair (LL) dan indeks plastisitas (IP) maka nilai kohesi tanah (c) semakin besarKata kunci : Batas Cair (LL), Indeks Plastisitas (IP), Kohesi (c), Korelasi
E-cadherin and NM23HI as metastasis predictors for various degrees of histological malignancy in invasive ductal carcinoma
Background: This study aims to analyze whether the expressions of E-cadherin and NM23HI can be used as predictors of ductal carcinoma metastasis in various degrees of malignancies.
Methods: Paraffin blocks were obtained from 97 patients with invasive breast ductal carcinoma with malignancy grade 1, 2 and 3 who came to several hospitals in Jakarta and Bandung from 2000 to 2006. Histopathological examinations of hematoxylin eosin slides of primary and secondary tumors were done to diagnose the degree of histological malignancy and metastasis status. Further, immunohistochemistry staining of E-cadherin, NM23HI and cytokeratin were done followed by scoring according to the number of positive cells and staining intensity. The associations of E-cadherin and NM23H1 expression with the presence of metastasis and grade of histological malignancy were analyzed.
Results: Subjects were 29-75 years old (mean: 48.19 years), with most subjects aged 40â45 years old, with malignancy grade 1, 2 and 3 of 18.56%, 45.36% and 36.1% respectively. There was a significant association between E-cadherin and NM23HI expression in primary tumors. The possibility of invasion and metastasis inhibition by positive E-cadherin and NM23HI was 14 and 11 times respectively compared to those with negative E-cadherin and/ or NM23HI expression. The ROC curve showed that E-cadherin (r= 0.755) and NM23HI (r= 0.827) expressions were strongly associated, sensitive and specific as metastasis markers. However, E-cadherin and NM23HI expression did not show significant association with histological degree of invasive ductal carcinoma.
Conclusion: E-cadherin and NM23HI expressions can be used as invasion and metastasis markers, but cannot be used as markers for the degree of histological malignancy of invasive ductal carcinoma. (Med J Indones 2011; 20:263-70
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
CD4+ Tumor-infiltrating Lymphocytes in Neoadjuvant Chemotherapy-treated Invasive Breast Cancer of No Special Type
Background:
Neoadjuvant chemotherapy (NAC) is an integral component of modern treatment for invasive breast cancer with no special type (IBC-NST). The interaction between the immune system and cancer, particularly through immune-infiltrating lymphocytes (TIL), continues to be studied to understand how treatments like NAC influence the disease progression and response to various therapies. This study was designed to investigate changes in the pattern of CD4+ TIL infiltration before and after NAC.
Methods:
This retrospective cohort study involved 32 participants. NAC was administered for 3 months, comprising six cycles of chemotherapy. Variables such as age, tumor size, grade, lymphovascular invasion, and regional lymph node metastasis (RLNM) were evaluated. Furthermore, the expression of receptors, estrogen receptor, progesterone receptor, human epidermal growth factor receptor-2 (HER-2), and Ki-67 was evaluated. Infiltration of the tumor by CD4+ TILs was assessed using immunohistochemistry, whereas other data were retrieved from the medical records of the participants. Data were analyzed using R software.
Results:
There was a significant increase in CD4+ TIL infiltration after NAC administration. Before NAC treatment, there were significant associations between stromal CD4+ TIL with tumor size after NAC (P = 0.047), intratumoral CD4+ TIL with age (P = 0.031), and intratumoral CD4+ TIL with HER-2 status (P = 0.037). After NAC treatment, intratumoral CD4+ TIL was associated with tumor size before NAC (P = 0.009) and RLNM (P = 0.026).
Conclusion:
NAC is associated with a significant increase in CD4+ TIL infiltration in patients with IBC-NST
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