1,721,053 research outputs found
Management of children living with tuberculosis patients; studies from Indonesia
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106974.pdf (Publisher’s version ) (Open Access)Radboud Universiteit Nijmegen, 08 april 2013Promotores : Ven, A.J.A.M. van der, Hill, P. Co-promotores : Crevel, R. van, Ruslami, R
High-dose rifampicin and other factors associated with outcome of tuberculous meningitis
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195161.pdf (Publisher’s version ) (Open Access)Radboud University, 19 oktober 2018Promotores : Crevel, R. van, Ruslami, R. Co-promotores : Aarnoutse, R.E., Ganiem, A.R.230 p
Etiology and clinical management of adult meningitis in Indonesia
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106968.pdf (Publisher’s version ) (Open Access)This thesis consists of 8 chapters and addresses the etiology, diagnosis, outcome and treatment of adult meningitis in Indonesia. The studies were conducted in Hasan Sadikin Hospital, Bandung, the referral hospital for West Java province, Indonesia between December 2006 and August 2012.
In a cohort of adult patients presenting with meningitis, we found that the vast majority of patients present with subacute meningitis, with high HIV prevalence. The most common diagnosis was TB meningitis, and cryptococcal meningitis was found in one-third of HIV patients. Bacterial meningitis was rare. The outcome was bad, approximately half of patients died during follow up, with HIV infection being the strongest risk factor for death.
Bacteriological confirmation of TB cases was found in 50% of cases. In-house real-time PCR (rt-PCR) targeting insertion sequence IS6110 had a higher sensitivity than microscopy and culture. In the search of other possible cause, we found that CSF PCR for Toxoplasma gondii was positive in one third of the HIV-infected population tested.
In the field of treatment, we examined if intensified antibiotic treatment containing a higher dose rifampicin intravenously and/or moxifloxacin may improve outcome. Intensified treatment regimens result in higher exposure in blood and CSF, did not result in increased toxicity, and high dose rifampicin was associated with a significant mortality reduction.
In the field of prevention, we investigated the prevalence and clinical significance of cryptococcal antigenemia in a cohort of HIV outpatient clinic. We found that 7.1% of ART-naïve patients with low CD4 count had a positive cryptococcal antigen. This cryptococcal antigenemia at baseline was strongly associated with the development of cryptococcal meningitis, early dropout, and early death. General lack of awareness of meningitis signs and symptoms was found both in laypeople and health providers. Measures to deal with this situation need to be formulated.Radboud Universiteit Nijmegen, 08 april 2013Promotor : Ven, A.J.A.M. van der Co-promotores : Crevel, R. van, Ruslami, R
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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