1,721,055 research outputs found

    An edge-driven 3D region-growing approach for upper airway morphology and volume evaluation in patients with Pierre Robin sequence

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    Abstract: Pierre Robin sequence (PRS) is a pathological condition responsible for a sequence of clinical events, such as breathing and feeding difficulties, that must be addressed to give the patient at least a chance to survive. By using medical imaging techniques, in a non-intrusive way, the surgeon has the opportunity to obtain 3D views, reconstruction of the regions of interest (ROIs), useful to increase understanding of the PRS patient’s condition. In this paper, a semi-automatic approach for segmentation of the upper airways is proposed. The implemented approach uses an edge-driven 3D region-growing algorithm to segment ROIs and 3D volume-rendering technique to reconstruct the 3D model of the upper airways. This method can be used to integrate information inside a medical decision support system, making it possible to enhance medical evaluation. The effectiveness of the proposed segmentation approach was evaluated using Jaccard (92.1733%) and dice (94.6441%) similarity indices and specificity (96.8895%) and sensitivity (97.6682%) rates. The proposed method achieved an average computation time reduced by a 16x factor with respect to manual segmentation

    A framework for data-driven adaptive GUI generation based on DICOM

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    Computer applications for diagnostic medical imaging provide generally a wide range of tools to support physicians in their daily diagnosis activities. Unfortunately, some functionalities are specialized for specific diseases or imaging modalities, while other ones are useless for the images under investigation. Nevertheless, the corresponding Graphical User Interface (GUI) widgets are still present on the screen reducing the image visualization area. As a consequence, the physician may be affected by cognitive overload and visual stress causing a degradation of performances, mainly due to unuseful widgets. In clinical environments, a GUI must represent a sequence of steps for image investigation following a well-defined workflow. This paper proposes a software framework aimed at addressing the issues outlined before. Specifically, we designed a DICOM based mechanism of data-driven GUI generation, referring to the examined body part and imaging modality as well as to the medical image analysis task to perform. In this way, the self-configuring GUI is generated on-the-fly, so that just specific functionalities are active according to the current clinical scenario. Such a solution provides also a tight integration with the DICOM standard, which considers various aspects of the technology in medicine but does not address GUI specification issues. The proposed workflow is designed for diagnostic workstations with a local file system on an interchange media acting inside or outside the hospital ward. Accordingly, the DICOMDIR conceptual data model, defined by a hierarchical structure, is exploited and extended to include the GUI information thanks to a new Information Object Module (IOM), which reuses the DICOM information model. The proposed framework exploits the DICOM standard representing an enabling technology for an auto-consistent solution in medical diagnostic applications. In this paper we present a detailed description of the framework, its software design, and a proof-of-concept implementation as a suitable plug-in of the OsiriX imaging software

    Resource-efficient hardware implementation of a neural-based node for automatic fingerprint classification

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    Modern mobile communication networks and Internet of Things are paving the way to ubiquitous and mobile computing. On the other hand, several new computing paradigms, such as edge computing, demand for high computational capabilities on specific network nodes. Ubiquitous environments require a large number of distributed user identification nodes enabling a secure platform for resources, services and information management. Biometric systems represent a useful option to the typical identification systems. An accurate automatic fingerprint classification module provides a valuable indexing scheme that allows for effective matching in large fingerprint databases. In this work, an efficient embedded fingerprint classification node based on the fusion of a Weightless Neural Network architecture and a technique, namely Virtual Neuron, which efficiently maps a neural network architecture into hardware resources, is presented. The key novelty of the proposed paper is a new neural-based classification methodology that can leverage devices and sensors with limited number of resources, allowing for resource-efficient hardware implementations. Furthermore, the classifier efficiency and the accuracy have been optimized to obtain high classification rate with the best trade-off between minimum area on chip and execution time. The proposed neural-based classifier analyzes a directional image, which is extracted from the original fingerprint image without any enhancement, and classifies the processed item into the five NIST NBIS classes. This approach has been designed for FPGA devices, by exploiting pipeline techniques for execution time reduction. Experimental results, based on a 10-fold cross-validation strategy, show an overall average classification rate of 90.08% on the whole official FVC2002DB2 database

    Personalizing Seizure Detection for Individual Patients by Optimal Selection of EEG Signals

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    Electroencephalography is a widely used non-invasive method for monitoring brain electrical activity, critical for diagnosing and managing neurological disorders such as epilepsy. While clinical standards use 21 electrodes to capture comprehensive neural signals, a personalized approach can enhance performance by selecting patient-specific channels, reducing noise and redundancy. This study introduces an innovative, lightweight deep learning system optimized for real-time seizure detection in personalized wearable devices. The system uses an efficient Convolutional Neural Network that processes data from just two channels. These channels are automatically selected using a data-driven mechanism that identifies the most informative scalp regions based on each patient’s unique seizure patterns. The proposed approach ensures high reliability, even with small datasets, and improves interpretability for clinicians by overcoming the limitations of more complex methods. The tailored channel selection boosts detection accuracy and ensures robust performance across different seizure types while reducing the computational burden typical of multi-electrode systems. Validation on the publicly available CHB-MIT dataset achieved an average balanced accuracy of 0.83 and a false-positive rate of approximately 0.1/h. The system’s performance matches, and in some cases outperforms, state-of-the-art systems that use four fixed channels in temporal regions, demonstrating the potential of two-channel wearable solutions, specifically with a non-negligible 30% reduction in the false-positive rate. This interpretable, patient-specific method enables the development of personalized, efficient, and compact wearable devices for reliable seizure detection in everyday life

    Biochemical parameter estimation vs. benchmark functions:a comparative study of optimization performance and representation design

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    Computational Intelligence methods, which include Evolutionary Computation and Swarm Intelligence, can efficiently and effectively identify optimal solutions to complex optimization problems by exploiting the cooperative and competitive interplay among their individuals. The exploration and exploitation capabilities of these meta-heuristics are typically assessed by considering well-known suites of benchmark functions, specifically designed for numerical global optimization purposes. However, their performances could drastically change in the case of real-world optimization problems. In this paper, we investigate this issue by considering the Parameter Estimation (PE) of biochemical systems, a common computational problem in the field of Systems Biology. In order to evaluate the effectiveness of various meta-heuristics in solving the PE problem, we compare their performance by considering a set of benchmark functions and a set of synthetic biochemical models characterized by a search space with an increasing number of dimensions. Our results show that some state-of-the-art optimization methods – able to largely outperform the other meta-heuristics on benchmark functions – are characterized by considerably poor performances when applied to the PE problem. We also show that a limiting factor of these optimization methods concerns the representation of the solutions: indeed, by means of a simple semantic transformation, it is possible to turn these algorithms into competitive alternatives. We corroborate this finding by performing the PE of a model of metabolic pathways in red blood cells. Overall, in this work we state that classic benchmark functions cannot be fully representative of all the features that make real-world optimization problems hard to solve. This is the case, in particular, of the PE of biochemical systems. We also show that optimization problems must be carefully analyzed to select an appropriate representation, in order to actually obtain the performance promised by benchmark results

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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