1,721,204 research outputs found
Un approccio stocastico-simulativo per le scelte di finanziamento con applicazione
No full textIn questo lavoro si analizza la situazione di una delle imprese turistico-alberghiere più importanti del lido di Sottomarina di Chioggia relativamente alla decisione da parte della Proprietà di effettuare un cospicuo investimento nella struttura ricettiva, o di cedere la struttura medesima. Questa decisione dovrà basarsi sulla valutazione di alcune importanti questioni: dapprima si dovranno valutare le prospettive economiche future del settore turistico di Sottomarina, cercando di capire se sussistono i presupposti per una riqualificazione regionale e nazionale del turismo balneare; poi si dovrà verificare se la struttura economico-aziendale dell’impresa potrà sopportare il peso di un finanziamento, stimato in circa 4 miliardi di lire italiane, necessario per la realizzazione dei lavori di riammodernamento della struttura. Proprio quest’ultima valutazione costituirà il centro tematico di questa trattazione: mediante l’applicazione di un modello stocastico-simulativo opportunamente sviluppato verranno effettuate una serie di simulazioni fina-lizzate a fornire una base su cui poter effettuare la valutazione e, quindi, scegliere se continuare nell’attività, o se cedere definitivamente l’impresa
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
In-work benefits for married couples. An ex-ante evaluation of EITC and WTC in Italy
No full textThis paper investigates labor supply and redistributive effects of in-work benefits for
Italian married couples using a tax-benefit microsimulation model and a multi-sectoral
discrete choice model of labor supply. We consider in-work benefits based on the
Earned Income Tax Credit (EITC) and the Working Tax Credit (WTC) existing in the US
and the UK, respectively. The standard design of these income support mechanisms is
however augmented with a premium for two-earner households to avoid potential
disincentive effects on secondary earners. Revenue neutral policy simulations show that
our reforms may greatly improve the current Italian tax-benefit system in terms of both
incentive and redistributive effects. Furthermore, neglecting sector-specific attributes
of the various job opportunities may lead to overstated estimates of the policy effects
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Natural Products with Toll-Like Receptor 4 Antagonist Activity
No full textToll-Like Receptors (TLRs) are the innate immunity receptors that play an activating role when interacting with molecules released by bacteria and viruses (PAMPs, pathogen-associated molecular patterns) or with molecules released by injured cells and tissues (DAMPs, danger-associated molecular patterns). TLR triggering leads to the induction of proinflammatory cytokines and chemokines, driving the activation of both innate and adaptive immunity. In particular, Toll-Like Receptor 4 (TLR4) has been described to be involved in the inflammatory processes observed in several pathologies (such as ischemia/reperfusion injury, neuropathic pain, neurodegenerative diseases, and cancer). Molecules obtained by natural sources have been discovered to exert an anti-inflammatory action by targeting TLR4 activation pathways. This review focuses on TLR4 antagonists obtained from bacteria, cyanobacteria, and plants
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