2,862 research outputs found
Applications of machine learning in biophotonics and laser metrology
No full textRecently, optical technologies have found several applications in fields including biophotonics, precision metrology and wavelength scale sensors. However, to gather statistically relevant information and analysis these methods require large amount of measurements. Current linear multivariate methods such as principal component analysis or linear discriminant analysis are not sufficient to analyze these big datasets with non-linear variability. Recently, the application of deep learning based artificial neural networks have found an upsurge in various areas of science ranging from quantum physics to evolutionary biology, providing an enhancement in the efficiency of various techniques. This thesis focuses on the applications of machine learning with the goal to enhance different aspects of biophotonics.
Firstly, this thesis explores the application machine learning to enhance the label-free characterization of cells of the immune system using Raman spectroscopy and digital holographic microscopy. The combination of deep learning with digital holographic microscopy provides a route towards a high throughput hemogram device which would be useful for the classification of clinically important immune cells with morphological similarities but different functions.
Following this, the applications of deep learning are explored in the regime of precision optical metrology for the development of a laser speckle wavemeter with a high dynamic range with an additional application for the development of a binary speckle based spectrometer.
Finally, the application of machine learning based methods are also explored to improve the sensitivity of the chirped guided mode biosensor. A comparison between the linear method of principal component analysis and direct Fano fitting is drawn which is followed by the application of multi layered perceptron for further improvement."This work was supported by Medical Research Scotland [Grant Ph.D. 873-2015],
which provided an opportunity of an industrial PhD with M Squared Lasers." -- Acknowledgement
Introduction of 'patient safety' module to undergraduate medical students through an interactive workshop
No full textBackground: The World Health Organization (WHO) had developed a curriculum guide designed to shape foundation knowledge and skills of medical students to sensitise them regarding 'Patient Safety'. 'Patient Safety' is not emphasised in the current undergraduate (UG) medical curriculum. This study is an attempt to know the effectiveness of introducing a 'Patient Safety' Module based on the WHO's proposed curriculum, through an interactive workshop for UG medical students.
Methods: This cross-sectional study was conducted with 77 students of 2nd year Bachelor of Medicine, Bachelor of Surgery (MBBS). Three topics of the WHO's 'Patient Safety Curriculum' were taught through an 'Interactive workshop' and a study tool, comprising of multiple-choice question and Likert scale. A questionnaire was also administered pre- and post-workshop, followed by a 'field activity' which allowed students to apply their newly learnt knowledge in a real hospital setting. Feedback was taken and qualitatively analysed.
Results: The mean score of first section of the study tool was 9.2 (45.9%) in pre-test and 14.6 (73.2%) in post-test, with a positive difference of 5.5 (27.4%) marks. The analysis of section 2 showed a significant positive change in the knowledge level, but a non-significant change was noted for the level of agreement, own ability to influence, personal attitudes with regard to patient safety and expectations about patient care. Overall analysis of the second section revealed a significant change to the positive side.
Conclusions: 'Interactive Workshop' significantly increased the knowledge regarding patient safety, and therefore, it is an effective method to teach 'patient Safety' to UG medical students
Data for Gupta et al., "Estimating the Meridional Extent of Adiabatic Mixing in the Stratosphere using Age-of-Air", JGR:Atmospheres,
No full textModel data and post-processed data supporting the creation of the manuscript "Estimating the Meridional Extent of Adiabatic Mixing in the Stratosphere using Age-of-Air" submitted to JGR:Atmospheres in August 2022.
1) The netCDF files created through post-processing of full model data in FORTRAN are shared in the /data/ directory. These file contains the zonal mean circulation statistics based on Gupta et al. (2020), age-of-air transport diagnostics based on Linz et al. (2021), and the novel \Gamma-\Theta circulation streamfunction introduced in this study. The /data/ directory also contains MATLAB .mat data files for the transport diagnostics obtained from WACCM. 150 days of actual GFDL-FV3 model data in the northern hemisphere, between 0.1 hPa-500 hPa pressure levels is also provided to support external computations and validation.
2) The Jupyter notebook used for final computation and figures production is provided in .ipynb, .html and .pdf formats in /code/. All the files referred to in the notebook are stored in the /data/ directory.
Corresponding author : Aman Gupta, [email protected], [email protected], [email protected]
A prospective study of incidence and risk factors for secondary glaucoma after penetrating keratoplasty
No full textAim: To carry out a prospective study to analyze the incidence and risk factors for secondary glaucoma after penetrating keratoplasty (PK). Materials and Methods: Three hundred and eleven consecutive penetrating keratoplasties that were performed between January 1, 2006, and December 31, 2008, with a follow-up of 12 months were prospectively analyzed to determine the factors associated with postoperative glaucoma. Results: Of 311 eyes, secondary glaucoma developed in 57 cases. This yields an incidence of 18.3%. In conditions, such as aphakic bullous keratopathy, the incidence of post-PK glaucoma was 3.0%; in pseudophakic bullous keratopathy 14.0%, and in cases of failed graft 16.0%, while in cases of corneal ulcer and corneal opacity it was 49.0% and 18.0%, respectively. Conclusion: We conclude in our study that the incidence of glaucoma developing post-PK was highest in phakic eyes, which may be due to the formation of posterior synechiae and development of intumescent cataract. Higher incidence of glaucoma developing in infective cases could be due to recipient hot eye and the high incidence in cases of large graft could be attributed to the formation of peripheral anterior synechiae
Corrigendum: Capital Inflows and House Prices: Aggregate and Regional Evidence from China
No full textIn the paper ‘Capital Inflows and House Prices: Aggregate and Regional Evidence from China’ by H. An, et al., printed in the December 2016 issue, there was a missing acknowledgement section for funding resources.
On page 451, the acknowledgement section should appear after the corresponding information as:
“Correspondence: Rakesh Gupta, Department of Accounting, Finance and Economics, Griffith Business School, Griffith University, Nathan Campus QLD 4111. [email protected]
*This work was financially supported by the Humanities and Social Science Foundation of Ministry of Education of China (16YJA790001).”
The author apologises for this error and any confusion it may have caused.No Full Tex
First person – Akash Gupta
No full textFirst Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers promote themselves alongside their papers. Akash Gupta is first author on ‘A novel and cost-effective ex vivo orthotopic model for the study of human breast cancer in mouse mammary gland organ culture’, published in BiO. Akash conducted the research described in this article while a PhD Scholar in Rajendra Mehta's lab at IIT Research Institute, Chicago, USA. He is now an assistant research scientist in the lab of Syreeta L. Tilghman at the University of Arizona, Department of Medicine, Tucson, USA, investigating drug efficacy modeling using human organoids culture for the treatment of cancers
Engineering materials : research, applications and advances / author, K.M. Gupta.
No full text"A CRC title."Includes bibliographical references and index.596 p.
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