139,863 research outputs found

    5% lidocaine medicated plaster double effect in a case of orofacial localized neuropathic pain

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    Roberto Casale,1,2 Yuriy Romanenko,2,3 Massimo Allegri4–6 1Department of Clinical Neurophysiology and Pain Rehabilitation Unit, Foundation "Salvatore Maugeri", Research and Care Institute, IRCCS, Pavia, Italy; 2EFIC Montescano Pain School, Montescano, Italy; 3Department of Neurology, Lugansk City Hospital 4, Lugansk, Ukraine; 4Department of Clinical, Surgical, Diagnostic and Pediatric Sciences University of Pavia, Pavia, Italy; 5Pain Therapy Service Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; 6SIMPAR group, Pavia, Italy Abstract: Localized neuropathic pain (LNP) is a type of neuropathic pain that is characterized by “consistent and limited area(s) of maximum pain associated with negative or positive sensory signs and/or spontaneous symptoms characteristic of neuropathic pain”. This definition encompasses a huge number of neuropathic orofacial pain syndromes. We present a case report of a patient who was affected with sleep apnea syndrome treated with nocturnal oxygen mask delivery, in whom orofacial LNP hampered the wearing of a mask due to unbearable burning and throbbing pain. The application of 5% lidocaine medicated plaster during the night led to an impressive reduction of both the pain level and the size of the painful area due to the plaster's pharmacological mechanisms, which were associated with a secondary benefit due to its mechanical protective action. This case report shows how these two factors could be of clinical value and have to be considered more systematically in the treatment of LNP in reducing pain and the size of the painful area. Keywords: trigeminal pain, localized neuropathic pain, topical treatment, 5% lidocaine medicated plaste

    Nitrogen doping and the performance of superconducting radio-frequency niobium cavities: insights from neutron diffraction and neutron Compton scattering

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    Neutron Compton scattering and neutron diffraction have been applied to investigate the influence of nitrogen doping of niobium on the performance of superconducting radio-frequency niobium cavities. To this end, a comparative study of the neutronic response of two samples has been performed. An electro-polished and nitrogen-doped niobium sample was compared with a standard, a niobium sample that has only undergone the electro-polishing procedure. The first piece of information, provided by neutron diffraction, is that additional conditioning of the electro-polished cavity material, through doping with nitrogen, leads to a systematically larger niobium lattice expansion, which provides an upper conservative limit of nitrogen concentration consistent with values reported in the literature. Furthermore, neutron Compton scattering shows a broadening of the niobium momentum distribution in the nitrogen-doped sample, as compared to the standard, thus indicating an increased degree of ordering and binding of niobium in the metal lattice. On the whole, these observations suggest that nitrogen-doping leads to some degree of lattice ordering, most likely due to increased hydrogen trapping, in agreement with previous results using surface spectroscopy

    Spatially-localized time dependent solutions including turbulence and their interactions in 2D Kolmogorov flow

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    In 2D Kolmogorov flow in small aspect ratio domains, spatially-localized solutions such as kink, traveling or time-dependent kink-antikink pars coexist. However, the conservation of the flow rate in the y direction strongly restrict combination of localized solutions and their positioning. We find that by adding a homogeneous flow U y their positioning is controlled and each of localized solutions including a spatially-localized chaos is isolated. Numerical results suggest that these isolated solutions can be elements constructing a whole flow

    Characteristics of overlap region in high-Reynolds number turbulent channel flow

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    Direct numerical simulation of the fully developed turbulent channel flows have been carried out at the Reynolds number based on the friction velocity and the channel half width, 2000, 4000 and 8000. A hybrid 10th order accurate finite difference scheme in the stream and spanwise directions, and a second-order scheme in the wall-normal direction is adapted as the spatial discretization method. We observed the plateau profiles in the indicator function corresponded to the von Karman constant. Furthermore, second peak of streamwise pre-multiplied spectra were appeared in the same wall normal height, 300 < y+ < 600, in case of Re = 4000. Nevertheless, the effects of the lager than the channel half height scale on the streamwise turbulent intensity are fixed contributions without dependence on Reynolds number. These results suggested that the new streamwise vortexes are formed between buffer layer and outer layer with increasing of Reynolds number

    Rapid emergence of independent "chromosomal lineages" in silvered-leaf monkey triggered by Y/autosome translocation

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    Sex/autosome translocations are rare events. The only known example in catarrhines is in the silvered-leaf monkey. Here the Y chromosome was reciprocally translocated with chromosome 1. The rearrangement produced an X1X2Y1Y2sex chromosome system. At least three chromosomal variants of the intact chromosome 1 are known to exist. We characterized in high resolution the translocation products (Y1and Y2) and the polymorphic forms of the intact chromosome 1 with a panel of more than 150 human BAC clones. We showed that the translocation products were extremely rearranged, in contrast to the high level of marker order conservation of the other silvered-leaf monkey chromosomes. Surprisingly, each translocation product appeared to form independent "chromosome lineages"; each having a myriad of distinct rearrangements. We reconstructed the evolutionary history of the translocation products by comparing the homologous chromosomes of two other colobine species: the African mantled guereza and the Indian langur. The results showed a massive reuse of breakpoints: only 12, out of the 40 breaks occurred in domains never reused in other rearrangements, while, strikingly, some domains were used up to four times. Such frequent breakpoint reuse if proved to be a general phenomenon has profound implications for mechanisms of chromosome evolution

    La 'circunstancia' de 'Herederos y Pretendientes

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    In June 2010, the Ortega y Gasset Foundation hosted a Conference about the “Spanish Philosophical Transition” in order to debate the book of Francisco Vázquez, La filosofía española. Herederos y Pretendientes. Una lectura sociológica (1963-1990), recently published. This paper is the author’s response to criticism raised in the Conference and to published reviews received by this book. First, the author summarized the argument of Herederos y pretendientes. Secondly he responds and takes into account the most important objections against the book’s hypothesis and methodology. Finally the author evaluates the favorable judgments received by the book and suggests the limits of the historian’s task.Fundación Ortega y Gasset-Marañó

    Author self-citation in orthodontics is associated with author origin and gender.

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    BACKGROUND The aims of this bibliometric study were to determine author self-citation trends in high-impact orthodontic literature and to investigate possible association between self-citation and publication characteristics. METHODS Six orthodontic journals with the highest impact factor as ranked by 2017 Journal Citation Reports were screened for a full publication year (2018) for original research articles, reviews, and case reports. Eligible articles were scrutinized for article and author characteristics and citation metrics. Univariable and multivariable negative binomial regression was used to examine associations between self-citation incidence and publication characteristics. RESULTS Medians for author self-citation rate of the most self-citing authors and self-citations were 3.03% (range 0-50) and 1 (range 0-19), respectively. In the univariable analysis, there was no association between self-citation counts and study type (P = 0.41), article topic (P = 0.61), number of authors (P = 0.62), and rank of authors (P = 0.56). Author origin (P = 0.001), gender (P = 0.001) and journal (P = 0.05) were associated with self-citation counts and in the multivariable analysis only origin and gender remained strong self-citation predictors. Asian authors and females self-cited significantly less often than all other regions and male authors. CONCLUSIONS Authors in orthodontics do not self-cite at a frequency that suggests potential citation manipulation. Author origin and gender were the only variables associated with citations counts. More bibliometric research is necessary to draw solid conclusions about author self-citation trends in orthodontic literature

    Overview of the Author Profiling Task at PAN 2013

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    [EN] This overview presents the framework and results for the Author Profiling task at PAN 2013. We describe in detail the corpus and its characteristics, and the evaluation framework we used to measure the participants performance to solve the problem of identifying age and gender from anonymous texts. Finally, the approaches of the 21 participants and their results are described.The author profiling task @PAN-2013 was an activity of the WIQ-EI IRSES project (Grant No. 269180) within the FP 7 Marie Curie People Framework of the European Commission. We want to thank the Forensic Lab of the Universitat Pompeu Fabra Barcelona for sponsoring the award for the winner team. The work of the first author was partially funded by Autoritas Consulting SA and by Ministerio de Economía y Competitividad de España under grant ECOPORTUNITY IPT-2012-1220-430000. The work of the second author was in the framework the DIANA-APPLICATIONS-Finding Hidden Knowledge in Texts: Applications (TIN2012-38603-C02-01) project, and the VLC/CAMPUS Microcluster on Multimodal Interaction in Intelligent Systems. The work of fifth author was funded in part by the Swiss National Science Foundation (SNF) project "Mining Conversational Content for Topic Modelling and Author Identification (ChatMiner)" under grant number 200021_130208.Rangel, F.; Rosso, P.; Koppel, M.; Stamatatos, E.; Inches, G. (2013). Overview of the Author Profiling Task at PAN 2013. CLEF Conference on Multilingual and Multimodal Information Access Evaluation. 352-365. https://riunet.upv.es/handle/10251/46636S35236

    Author Co-Citation Analysis (ACA): a powerful tool for representing implicit knowledge of scholar knowledge workers

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    In the last decade, knowledge has emerged as one of the most important and valuable organizational assets. Gradually this importance caused to emergence of new discipline entitled ―knowledge management‖. However one of the major challenges of knowledge management is conversion implicit or tacit knowledge to explicit knowledge. Thus Making knowledge visible so that it can be better accessed, discussed, valued or generally managed is a long-standing objective in knowledge management. Accordingly in this paper author co- citation analysis (ACA) will be proposed as an efficient technique of knowledge visualization in academia (Scholar knowledge workers)

    Semana Santa y su simbología. 5 Segunda época Año 3 (2019) enero-junio. Rutas de Campo. Trabajo de Campo: Iztapalapa: memoria y cultura

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    Los dos grandes momentos en torno a los cuales gira la cosmovisión católica, el nacimiento de Jesús y su muerte, han dado lugar, el primero, a la celebración de la Navidad, y el segundo, a la conmemoración de Semana Santa. En este texto nos ocuparemos de los años finales de la vida de Jesús, pues es precisamente Semana Santa la celebración litúrgica con que se recuerda su Pasión y su muerte. Recordemos que, en este contexto, el término “pasión” hace referencia al sufrimiento y a la serie de tormentos a que fue sometido Jesús poco antes de su muerte en la cruz, que todos conocemos.Altamirano, Ignacio Manuel (1974). Paisajes y leyendas. Tradiciones y costumbres de México. México: Porrúa.Calendario de fiestas tradicionales (1988). México: Dirección General de Culturas Populares-SEP.Calendario Litúrgico Pastoral 1991 (1990). México: Obra Nacional de la Buena Prensa.Campos, Rubén M. (1929). El folklore literario en México. Investigación de la producción literaria popular. México: Talleres Gráficos de la Nación._____ (1958). “Semana Santa”. En Fiesta. México: Talleres de la Secretaría de Hacienda.Castelló Iturbide, María Teresa (1958). “El altar del Viernes de Dolores”. En Fiesta. México: Talleres de la Secretaría de Hacienda.Catalán Blanco, Juan Carlos (s.f.). “Las fiestas de carnestolendas y la celebración de la Semana Santa en la época colonial” [inédito]. s.l.: Dirección General de Culturas Populares de Guerrero-SEP.Cid, Carlos, y Manuel Riu (1965). Historia de las religiones. Barcelona: Sopena._____ (1987). Compendio de historia sagrada y de la historia de la Iglesia. México: Progreso.Crumrine N., Roos (1979). “Cuaresma”. En Gran Enciclopedia Rialp. Madrid: Rialp.Estrada, Genaro (1945). Visionario de la Nueva España. México: Patria.Estrada, Humberto (1985). “La cuaresma” [inédito]. s.l.: Dirección General de Culturas Populares-SEP.Foster, George M. (1962). Cultura y conquista. Xalapa: Universidad Veracruzana.García Cubas, Antonio (1945). El libro de mis recuerdos. México: Patria.González Obregón, Luis (1936). Croniquillas de la Nueva España. México: Botas.____(1941). Las calles de México. México: Botas.Horcasitas, Fernando (1974). El teatro náhuatl: época novohispana y moderna. México: IIH-UNAM.Iglesias y Cabrera, Sonia C. (1996). Tradiciones de Cuaresma y Semana Santa. México: Museo Nacional de Culturas Populares-Dirección General de Culturas Populares._____ (2001). La semana Santa en México. Con la muerte en la cruz. México: Dirección General de Culturas Populares.Lercaro, Giacomo (1960). ¿Cuál es el vocabulario de la liturgia católica? México: Novaro.Macgowan, Kenneth, y William Melnitz (1964). Las edades de oro del teatro. México: FCE.Mendieta, Gerónimo de (1945). Historia eclesiástica indiana. México: Salvador Sánchez.Mendoza, Vicente T., y Adalberto Fuentes Cruz (1945). “Drama de la Pasión intitulado: el drama del Gólgota, que se representa en la delegación de Milpa Alta, D.F.”. Anuario de la Sociedad Folklórica de México, 6.Moreno Toscano, Alejandra (1981). “La conquista espiritual”. En Historia general de México. México: El Colegio de México.Olavarría Ferrari, Enrique de (1953). “Pasión de Cristo”. En Enciclopedia de la religión católica [t. V]. Barcelona: Dalma y Jovier._____ (1961). Reseña del teatro en México. México: Porrúa.Pike E., Royston (1986). Diccionario de religiones. México: FCE.Prieto, Guillermo (1969). Memorias de mis tiempos. México: Patria.Rodríguez, Mariángela (1991). Hacia la estrella con la Pasión y la ciudad a cuestas. Semana Santa en Iztapalapa. México: Ediciones de la Casa Chata-CIESAS.Sociedad Bíblica Británica y Extranjera de Londres (1929). La Santa Biblia. Londres: SBBEL.Vetancurt, Agustín de (1941). Teatro mexicano: descripción breve de los sucesos exemplares de la Nueva España en el mundo occidental de las Indias. Madrid: J. Porrúa.Verti, Sebastián (1991). Tradiciones mexicanas. México: Diana.Weckmann, Luis (1984). La herencia medieval de México. México: FCE
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