184,343 research outputs found
Phyllis Zuniga Rodriguez, Hispanic Oral Histories, Accn 1369
No full textRodriguez (b. 1919) describes her childhood in Nevada and her marriage at age 13 when her father died. She also talks about life as a migrant worker, labor agents, life in Bingham, Utah, and raising her children. Interviewed by Sandra T. Fuller, 52 pages
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A letter from Alonzo T. “Al” Rodriguez to Dr. Hector P. Garcia, asking him for assistance in obtaining a nomination for District Judge from Governor Mark White.
No full textA letter from Alonzo T. “Al” Rodriguez to Dr. Hector P. Garcia, asking him for assistance in obtaining a nomination for District Judge from Governor Mark White
Exploring the relationship between plant sterol bioaccessibility and lipolysis of enriched bread in senior digestion conditions
No full textPlant sterol (PS)-enriched foods are considered a valuable tool for the prevention of cardiovascular diseases, especially in senior population
(> 65 years). Despite its relevant effect on human health, there are few studies on the fate of food and PS during digestion under
senior adult conditions1,2. The aim of this study was to determine the PS bioaccessibility (BA) and lipolysis from a PS-enriched wholemeal
rye bread under senior adult conditions. The bread was subjected to in vitro digestion under older adult conditions (reduction of enzyme
activity and agitation, modification of pH and increase of digestion time) at (i) gastric step, (ii) gastric and intestinal step, and (iii) INFOGEST
2.0 method with cholesterol esterase as control. The PS content in bread and in the obtained bioaccessible fractions (BF) were determined
by gas chromatography-mass spectrometry (GC-MS), in order to calculate the BAs3. The main lipid classes in both the bread and
BF were determined by GC-flame ionization detection (FID)4. The total PS content in the bread was 1.6 g/100 g, with b-sitosterol (81.3%)
> campesterol and sitostanol (6.8%) > campestanol (1.7%) > stigmasterol, Δ5-avenasterol, Δ5,24-stigmastadienol, Δ7-stigmastenol and Δ7-
avenasterol (< 1%). The BA of total PS after the control digestion was 11.6%, with sitostanol as the most bioaccessible sterol (18.5%).
The modified gastric step conditions led to a higher BA of total PS (values of 16.1%), with sitostanol remaining as the most bioaccessible
sterol (23.1%). The total PS BA obtained with the gastric and intestinal adaptations was not significantly different with respect to that
of the control (9.9% of BA), with sitostanol and stigmasterol displaying the highest BA (16.6 and 15.6%, respectively). The lipid profile
in the bread confirmed that free sterols were the major lipid class (82.1%, in agreement with the PS enrichment of the bread), followed
by triacylglycerols (12.3%), and free fatty acids, diacylglycerols, monoacylglycerols, esterified sterols and tocopherols (< 1.6%). The total
lipid profile obtained in all digestion conditions here tested showed a predominant abundance of free fatty acids (43.2–48.2%) and free
sterols (47.2–51.2%). In this case, significant differences were observed only in the intestinal phase, where a higher abundance of esterified
sterols (8.8%), diacylglycerols (31.7%), and triacylglycerols (67.1%) was found in the modified condition with respect to the control
method. Therefore, our study suggests that senior digestion conditions do not significantly affect the BA of PS in PS-enriched bread,
despite the decrease in lipolysis. However, further studies are needed to confirm these results for a better understanding of PS fate
in aging populations.
Authors thank the financial support from project PID2019-104167RB-I00/AEI/10.13039/501100011033, as well as from the Basic
Research Funding RFO of the Alma Mater Studiorum-University of Bologna. V. Blanco-Morales holds a grant for the requalification
of the Spanish university system from the Ministry of Universities of the Government of Spain (European Union, NextGenerationEU).
1 Makran et al., 2022. Trends Food Sci Technol. 129, 283-295.
2 Poli et al., 2021. Nutrients. 13, 2810.
3 Cuevas-Tena et al., 2017. Lipids. 52, 871-884;
4 Tappi et al., 2020. Foods, 9, 1485
Design and Thermal and Spectroscopic Characterization of novel architecture’s POSS nanoparticles
No full textPolyhedral oligomeric silsesquioxanes (POSSs), with Si vertices interconnected by –O– linkages, form three-dimensional nanometer size cage structures with substituents attached to silicon atoms. These substituents may contain reactive groups, such as hydroxyl or isocyanate. A combination of a rigid inorganic nanocore with organic vertex groups makes POSS molecules useful hybrid building blocks that can be chemically incorporated in the polymer matrix by copolymerization, grafting or reactive blending, or physically mixed by solvent casting or polymer processing by using, for example, the extrusion technique [1]. The use of POSSs for making polymer composites has grown exponentially since the last few years of the 20th century. In comparison with the other most commonly used fillers, POSSs possess the advantage of being molecules. Thus, this allows us to combine their nano-sized cage structures, which have dimensions that are similar to those of most polymer segments and produce a particular and exclusive chemical composition. These characteristics linked with their hybrid (inorganic–organic) nature allow researchers to modify POSS according to particular needs or original ideas, before incorporating them into polymers [2].
Figure 1. Molecular structure of the prepared and investigated POSSs
In this context, our research group at the University of Catania, in collaboration with eminent researchers in the field, tested the stabilization of different polymers, synthetics or naturals, such as polyethersulfone (PES), ethylene propylene diene monomer (EPDM), polyethylene oxide (PEO), and chitosan by the incorporation of polyhedral oligomeric silsesquioxanes (POSS) molecules [3-6]. Represented in their most common form by the symbol T8 and having a diameter usually falling in the range of 1.5–3 nm, POSS molecules comprise a silicon and oxygen cage completed by organic groups that are covalently bonded with silicon atoms. Novel architectures of POSS with various organic groups were synthesized by using corner capping reaction in order to verify their polimeryzability in the presence of monomer. In this work, after a spectroscopic investigation aiming at verify that the obtained molecules have the structure for which they were designed, their thermal behavior in terms of resistance to thermal degradation were evaluated by means of thermogravimetric analysis (TGA). The obtained temperatures at 5% mass loss (T5%) were compared with each other and with those of the POSSs previously designed and studied by us.
Bibliography
[1] Lichtenhan, J.D., Pielichowski, K., Blanco, I. POSS-Based Polymers. Polymers 2019, 11, 1727
[2] Blanco, I. The Rediscovery of POSS: A Molecule Rather than a Filler. Polymers 2018, 10, 904.
[3] Cicala, G., Blanco, I., Latteri, A., Ognibene, G., Agatino Bottino, F., Fragalà, M.E. PES/POSS Soluble Veils as Advanced Modifiers for Multifunctional Fiber Reinforced Composites. Polymers 2017, 9, 281
[4] Zaharescu, T., Blanco, I., Bottino, F.A. Antioxidant activity assisted by modified particle surface in POSS/EPDM hybrids. Appl. Surf. Sci. 2020, 509, 144702
[5] Legnani, L.; Iannazzo, D.; Pistone, A.; Celesti, C.; Giofrè, S.; Romeo, R.; Di Pietro, A.; Visalli, G.; Fresta, M.; Bottino, P.; et al. Functionalized polyhedral oligosilsesquioxane (POSS) based composites for bone tissue engineering: Synthesis, computational and biological studies. RSC Adv. 2020, 10, 11325–11334
[6] Stipanelov Vrandečić, N., Erceg, M., Andričić, B., Blanco, I., Bottino, F.A. Characterization of poly(ethylene oxide) modified with different phenyl hepta isobutyl polyhedral oligomeric silsesquioxanes. J. Therm. Anal. Calorim. 2020, 142, 1863–187
Regulation of the T helper cell type 1 transcription factor T-bet in coeliac disease mucosa
No full textBackground: In coeliac disease ( CD) mucosa, the histological lesion is associated with marked infiltration of T helper cell type 1 (Th1) cells. However, the molecular mechanisms which regulate Th1 cell differentiation in CD mucosa are unknown. Aims: To analyse expression of transcription factors which control the Th1 cell commitment in CD. Patients: Duodenal mucosal samples were taken from untreated CD patients and normal controls. Methods: Interferon gamma (IFN-gamma) and interleukin (IL)-4 RNA expression was examined in T lamina propria lymphocytes by quantitative reverse transcription-polymerase chain reaction. T-bet and STAT-4, two Th1 promoting transcription factors, and STAT-6 and GATA-3, transcription factors which govern T helper cell type 2 (Th2) cell polarisation, were examined in duodenal biopsies by western blotting. The effect of gliadin and IFN-gamma on expression of T-bet was examined in an ex vivo culture of biopsies taken from normal and treated CD patients. Results: As expected, IFN-gamma but not IL-4 RNA transcripts were increased in the mucosa of CD patients in comparison with controls. CD mucosal samples consistently exhibited higher levels of T-bet than controls. However, no difference in active STAT-4 expression was seen between CD patients and controls, suggesting that Th1 polarisation was not induced by local IL-12. GATA-3 and STAT-6 were also low in both CD and control mucosa. In normal duodenal biopsies, IFN-gamma stimulated T-bet through a STAT-1 dependent mechanism. Challenge of treated CD but not control biopsies with gliadin enhanced T-bet and this effect was also inhibited by STAT-1 inhibition. Conclusions: This study shows that activation of STAT-1 by IFN-gamma promotes T-bet in CD mucosa
Fracionamento do óleo essencial de Patchouli [Pogostemon cablin (Blanco) Benth.] obtido por extração supercrítica
No full textDissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Química.O fracionamento do óleo essencial de patchouli [Pogostemon cablin (Blanco) Benth.] extraído com dióxido de carbono supercrítico (CO2_SC) foi estudado. Este óleo essencial é muito usado pela indústria de cosméticos e perfumaria como excelente fixador de aromas. Adotando-se pressão e temperatura de trabalho em 100 bar e 32°C, respectivamente, foram estudados alguns parâmetros nunca antes averiguados para o patchouli. O trabalho se dividiu em quatro frentes de estudo: aumento de rendimento variando o tempo de extração e tempo estático; análise do tamanho ideal de partícula; épocas de colheita; composição química do óleo essencial. O tempo estático combinado com o tempo de coleta de amostras foi estudado com o objetivo de aumentar o rendimento do processo, resultando em um tempo ideal de 20 minutos de tempo estático e de tempo para coleta de amostras. Três tamanhos "médios" de partículas foram estudados à duas diferentes vazões de solvente. O tamanho de partícula ideal para a extração supercrítica do óleo essencial de patchouli foi de 0,346 mm à vazão de 1,2 L/min de CO2. Lotes de folhas de patchouli colhidas em diferentes épocas do ano foram usados para extração de seu óleo essencial. A época do ano nas quais se obtiveram melhores rendimentos foi no inverno. A composição química do óleo essencial de patchouli foi estudada com a intenção de saber a que tempo de processo os principais compostos de interesse (patchoulol e a-bulneseno) são extraídos. As amostras de óleo essencial analisadas forneceram resultados suficientes para se traçar o perfil de concentração destes compostos com o tempo de extração. Sabendo-se o tempo ideal de coleta de amostras, pode-se estabelecer um método de fracionamento para óleo essencial de patchouli. The fractionation of the essential oil of patchouli [Pogostemon cablin (Blanco) Benth.] extracted with supercritical carbon dioxide (CO2_SC) was studied. This oil is widely used by industries of cosmetics and fragrances. Bringing up of work pressure and temperature at 100 bar and 32 ° C, respectively, were studied some parameters never before investigated for the patchouli. The work was divided into four subjects of study: increasing yield varying the static period and the total time of extraction; analysis of the optimal particle size; harvest period; chemical composition of the essential oil. The static period combined with the time of collection of samples was studied with the objective of increasing the yield of the process, resulting in an ideal time of 20 minutes of static period and time for collection of samples. Three "averages" particles sizes were studied for two different flows of solvent. The ideal particle size for the supercritical extraction of essential oil of patchouli was 0.346 mm, at flow rate of 1.2 L / min of CO2. Lots of patchouli leaves harvested at different times of the year were used for extraction of its essential oil. The time of the year which it was obtained better yield is the winter. The chemical composition of the essential oil of patchouli was studied with the intention of knowing that process time the main compounds (patchoulol and a-bulnesene) are extracted. Samples of essential oil analyzed results provided sufficient to trace the profile of concentration of these compounds. Knowing the perfect time of collection of samples, can be possible to establish a method for the fractionation of patchouli essential oil
[3 Churches, Blanco, Texas]
No full textRecto: [imprinted on negative] 3 churces [sic], Blanco, Tex. Verso: [postmarked] Blanco Tex, Apr [illegible] 1910
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Oral History Interview with Victor Rodriguez, June 13-18, 2009
No full textInterview with Dr. Victor Rodriguez, educator and author of the memoir "The Bell Ringer," about his life and career. Dr. Rodriguez is a North Texas alumni, member of the UNT Athletic Hall of fame, member of the Geezles Fraternity, and pioneer Mexican American educator. Dr. Victor Rodriguez spotlights significant insights into his storied career through five eras: his early all-Hispanic elementary school training; his continued study and budding athletic prowess in the Edna, TX, school district; his Victoria Junior College athletic achievements and learning; his higher education, Geezle membership, and track accomplishments at North Texas State College; and his 37-year career as a teacher, coach, and superintendent in the San Antonio school district. Inspired by his Anglo third-grade teacher in an all-Hispanic school in Edna, TX, Rodriguez responded to his teacher's challenge to be a civic contributor by becoming a daily bell ringer at the local Catholic church (described in detail in his book, The Bell Ringer), a job requiring him to arise at 4:30 each morning and to run two miles one way amid nipping dogs to ring the bell. This discipline and activity would tap his athletic ability later as he surfaced as a distance district winner despite running barefoot, in blue jeans, and in an oversized t-shirt. From this beginning, he would emerge as a state champion and win a track scholarship to Victoria Junior College where he would win the national junior college title; that accomplishment would earn him track scholarship offers from many top-level four-year college programs of which he selected North Texas State College to continue his running and educational pursuits. While at NTSC, he joined the Geezle Fraternity and captured attributes of group cohesion, solidarity, and mutual benefit/trust. On the cinder track, his talents earned him gold medals in national events such as the Kansas and Drake Relays. After college and military service, Victor joined the San Antonio ISD to begin a 37-year career journey, first as a classroom teacher for bilingual children, then to increasing levels of responsibility as coach, teacher, principal, area coordinator, climaxing at the pinnacle of leadership as superintendent for the district. Along the way, he earned a PhD from the University of Texas-Austin and a year-long fellowship at Yale
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