550 research outputs found
Mackinnon, Roderick Alister, NX36928
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/400821Surname: MACKINNON. Given Name(s) or Initials: RODERICK ALISTER. Military Service Number or Last Known Location: NX36928. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 22822.220467
Item: [2016.0049.33114] "Mackinnon, Roderick Alister, NX36928
Rewilding Victoria: remembering and restoring nature in the city
No full textTo know what is, you must know what was. This is the simple truth that J.B. MacKinnon explores in his new book The once and future world: nature as it is, as it was, as it could be. The natural world, he argues, has been lost not only to human rapaciousness, but also through a great forgetting. MacKinnon calls on us to examine the nature of the past in order to "rewild" the earth in the future, "The history of nature is not only a lament," he writes."It is also an invitation to envision another world." MacKinnon is the author or co-author of four books of nonfiction, including The 100-mile diet (with Alisa Smith), a bestseller widely recognized as a catalyst of the local foods movement, His writing in print and online has won more than a dozen national and international awards, including Canada's highest prize for literary nonfiction. MacKinnon lives in Vancouver, Canada.Lansdowne Lecture SeriesFacultyUnreviewe
False Idyll
No full textA provocative essay awaits those who peruse prize-winning author J.B. MacKinnon\u27s article, False Idyll. MacKinnon posits that many of us romanticize nature as a sacred place ( one of succor and comfort) overlooking that most places visited have been tamed by humans. The absence of real wildness (predators that can kill us) creates an imaginary connection with nature instead of a tangible one. We settle for occasional visits to such sanctuaries and see little purpose in returning to a deeper and more risky engagement:\u27 Thus seeing only nurture in nature reinforces the concept that we are apart and above it
Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures
No full textHow calcium gates a potassium channel
Small-conductance Ca
2+
-activated K
+
(SK) channels are expressed throughout the nervous system and affect both the intrinsic excitability of neurons and synaptic transmission. An increase in the concentration of intracellular calcium opens the channels to conduct potassium across the cell membrane. Lee and MacKinnon report cryo–electron microscopy structures of human SK4-calmodulin channel complexes. Activation occurs when calcium binds to calmodulin, a protein with two lobes, known as C and N, separated by a flexible region. Each monomer in the channel tetramer binds constitutively to the C-lobe of calmodulin. The N-lobe of calmodulin is reasonably unconstrained until it binds calcium. With calcium bound, it then binds to the channel and induces conformational changes that open the pore.
Science
, this issue p.
508
</jats:p
Catharine MacKinnon e o sexo como dominação
No full textThe article discusses the work of feminist legal scholar Catharine MacKinnon and, in particular, her radical rejection of the liberal notion of “consent”. For the author, sexuality is an expression of male dominance; indeed, it reveals itself as “eroticization of domination”. In such society, there is no possibility of autonomous agency for women. We must undo the work of the internalization of dominant values, so that a genuine feminine consciousness can emerge. This is the backdrop of her controversial views on rape, pornography, prostitution or abortion. The article concludes that, while illuminating important aspects of domination, she simplifies in excess the discussion of autonomy in social agency.O artigo discute a obra da jurista feminista Catharine MacKinnon e, em particular, sua recusa radical à noção liberal de “consentimento”. Para a autora, a sexualidade é a expressão da dominação masculina; de fato, ela se revela como “erotização da dominação”. Numa sociedade assim organizada, não há possibilidade de agência autônoma para mulheres. É necessário desfazer o trabalho de introjeção dos valores dominantes, para que uma consciência feminina genuína possa emergir. Este é o pano de fundo das polêmicas posições de MacKinnon sobre estupro, pornografia e prostituição. O artigo conclui que, embora ilumine aspectos importantes da dominação, ela simplifica em excesso a discussão sobre a autonomia na agência social
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