339 research outputs found
Casein proteins as molecular chaperones
No full text© 2005 American Chemical SocietyPhilip E. Morgan, Teresa M. Treweek, Robyn A. Lindner, William E. Price, and John A. Carve
An insider's guide to working for the federal government: navigating all levels of government as a civil servant or contractor/ Dan Lindner.
No full textIncludes bibliographical references and index.With simple, to-the-point, explanations of the different branches and agencies of government, insider Dan Lindner guides prospective employees and contractors through the halls of bureaucracy, giving readers everything they need to know to excel in the federal environment.Preface -- 1. The Tricameral Form of Government -- 2. Departments and Agencies -- 3. The Civil Service -- 4. How to Get a Job -- 5. Retirement -- 6. Classified Work -- 7. Contractors -- 8. Staff Work -- 9. Excellence on the Job: Employee Dos and Don'ts -- 10. Managing-Supervision -- 11. Communication -- 12. Meetings and Presentations -- 13. Some Historical Case Studies -- Bibliography -- Index -- About the Author.1 online resource (viii, 196 pages
sj-doc-2-mdm-10.1177_0272989X231184461 – Supplemental material for Randomized Trial of the Choosing Wisely Consumer Questions and a Shared Decision-Making Video Intervention on Decision-Making Outcomes
No full textSupplemental material, sj-doc-2-mdm-10.1177_0272989X231184461 for Randomized Trial of the Choosing Wisely Consumer Questions and a Shared Decision-Making Video Intervention on Decision-Making Outcomes by Danielle Marie Muscat, Rachel Thompson, Erin Cvejic, Jenna Smith, Edward Hoi-fan Chang, Marguerite Tracy, Joshua Zadro, Robyn Lindner and Kirsten J. McCaffery in Medical Decision Making</p
sj-docx-1-mdm-10.1177_0272989X231184461 – Supplemental material for Randomized Trial of the Choosing Wisely Consumer Questions and a Shared Decision-Making Video Intervention on Decision-Making Outcomes
No full textSupplemental material, sj-docx-1-mdm-10.1177_0272989X231184461 for Randomized Trial of the Choosing Wisely Consumer Questions and a Shared Decision-Making Video Intervention on Decision-Making Outcomes by Danielle Marie Muscat, Rachel Thompson, Erin Cvejic, Jenna Smith, Edward Hoi-fan Chang, Marguerite Tracy, Joshua Zadro, Robyn Lindner and Kirsten J. McCaffery in Medical Decision Making</p
New records of Stratiomyidae (Diptera) from the Near East with a key to the species of Israel, Sinai and the Golan
No full textA supplement is given to the publications of the senior author (Lindner, 1974 and 1975) on the Stratiomyidae of the Near East. Pachygaster atra Panzer and Aspidacantha atra Kertesz (Pachygastrinae) are recorded from the area for the first time. The male of Heradina galeata Lindner is described for the first time. New synonyms are established, and a key is given to all the species recorded so far from the area
Researching the characteristics of stalkers
No full textDiplomska naloga Raziskovanje značilnosti zalezovalcev se osredotoča na pregled metodologije nekaterih obstoječih raziskav, ki se navezujejo na zalezovalce. Zalezovanje predstavlja kompleksen problem sodobnega časa, ki se dotika tako pravnih in psiholoških vidikov kot tudi družbe same. Velja za zapleteno obliko človeškega vedenja, ki ga je zaradi velikega obsega dejavnikov in zavedanja žrtve težko predvideti ter preprečevati. Raziskovalci se pri raziskovanju pogosto srečujejo s težavami, povezanimi z merjenjem občutljivih vedenj in motivacij zalezovalcev, zato je ustreznost merskih instrumentov in njihova izbira ključna za učinkovitejše razvijanje preventivnih in intervencijskih ukrepov. V diplomskem delu smo preverili, kako so značilnosti zalezovalcev raziskovali v obstoječi znanstveni literaturi s poudarkom na uporabljenih raziskovalnih pristopih, metodologiji in kakovosti zbranih podatkov. Glavni cilj je bil ugotoviti prednosti in pomanjkljivosti uporabljenih vprašalnikov. Analizirali smo vsebine 36 člankov, ki smo jih pridobili v podatkovni bazi Web Of Science in Cobiss. Ugotovili smo, da so metodološke značilnosti raziskav pogosto pomanjkljivo napisane. Raziskovalci so uporabili predvsem kombinacije prilagojenih avtorskih vprašalnikov, narejenih po literaturi drugih avtorjev in ocenjevalne lestvice. Vprašalniki so bili pogosteje navedeni kot veljavni, vendar delno kakovostni. Najpogosteje so raziskovalci uporabili neverjetnostno priložnostno in namensko vzorčenje. Majhni vzorci, možnost subjektivnosti, uporaba hipotetičnih scenarijev, napake samoporočanja in neodzivnost udeležencev so predstavljali najpogostejše omejitve raziskav.The thesis, Researching the characteristics of stalkers, focuses on reviewing the methodologies of existing studies on stalking. Stalking represents a multifaceted issue in modern society, involving legal, psychological and social dimensions. It is considered a complex form of human behaviour, which, due to the multitude of influencing factors and the victim\u27s awareness, is difficult to predict and prevent. Researchers often face challenges when studying sensitive behaviours and the motivation of stalkers, which is why appropriate measurement instruments are crucial for the effective development of preventive and intervention strategies. This thesis examines how the characteristics of stalkers have been studied in the existing scientific literature, with a focus on research approaches, methodologies and quality of collected data. The main goal was to determine the advantages and limitations of the questionnaires used. We have done a content analysis of 36 research articles retrieved from Web of Science and Cobiss. We found that the reporting of the methodologies was often insufficiently described. Most researchers relied on adapted, author-designed questionnaires and rating scales. The questionnaires were more frequently cited as valid but partly of limited quality. The most commonly used sampling methods were non-probability sampling, such as convenience and purposive sampling. Small samples, the possibility of bias, the use of hypothetical scenarios, self-reporting errors and non-responsiveness of participants represented the most common limitations of the studies
Finiteness and children with specific language impairment: an exploratory study
No full textChildren with specific language impairment (SLI) are well known for their difficulties in mastering the inflectional paradigms; in the case of learning German they also have problems with the appropriate verb position, in particular with the verb in second position. This paper explores the possibilities of applying a broader concept of finiteness to data from children with SLI in order to put their deficits, or rather their skills, into a wider perspective. The concept, as developed by Klein (1998, 2000), suggests that finiteness is tied to the assertion that a certain state of affairs is valid with regard to some topic time; that is, finiteness relates the propositional content to the topic component. Its realization involves the interaction of various grammatical devices and, possibly, lexical means like temporal adverbs. Furthermore, in the acquisition of finiteness it has been found that scope particles play a major role in both first- and second-language learning. The purpose of this paper is to analyze to what extent three German-learning children with SLI have mastered these grammatical and lexical means and to pinpoint the phase in the development of finiteness they have reached. The data to be examined are mostly narrative and taken from conversations and experiments. It will be shown that each child chooses a different developmental path to come to grips with the interaction of these devices
Mouse Hsp25, a small heat-shock protein. The role of its C-terminal extension in oligomerization and chaperone action
No full textThe definitive version is available at www.blackwell-synergy.comUnder conditions of cellular stress, small heat shock proteins (sHsps), e.g. Hsp25, stabilize unfolding proteins and prevent their precipitation from solution. 1H NMR spectroscopy has shown that mammalian sHsps possess short, polar and highly flexible C-terminal extensions. A mutant of mouse Hsp25 without this extension has been constructed. CD spectroscopy reveals some differences in secondary and tertiary structure between this mutant and the wild-type protein but analytical ultracentrifugation and electron microscopy show that the proteins have very similar oligomeric masses and quaternary structures. The mutant shows chaperone ability comparable to that of wild-type Hsp25 in a thermal aggregation assay using citrate synthase, but does not stabilize alpha-lactalbumin against precipitation following reduction with dithiothreitol. The accessible hydrophobic surface of the mutant protein is less than that of the wild-type protein and the mutant is also less stable at elevated temperature. 1H NMR spectroscopy reveals that deletion of the C-terminal extension of Hsp25 leads to induction of extra C-terminal flexibility in the molecule. Monitoring complex formation between Hsp25 and dithiothreitol-reduced alpha-lactalbumin by 1H NMR spectroscopy indicates that the C-terminal extension of Hsp25 retains its flexibility during this interaction. Overall, these data suggest that a highly flexible C-terminal extension in mammalian sHsps is required for full chaperone activity
Beiträge zur kombinierten Lichtstreuung in trüben Medien und an rauen Oberflächen
No full textDiese Arbeit beschäftigt sich mit der kombinierten Lichtstreuung in trüben Medien und an rauen Oberflächen. Die Arbeit enthält vier vom Autor veröffentlichte Artikel zum Thema der Herstellung rauer Oberflächen und der Wechselwirkung zwischen Lichtstreuung in trüben Medien und an rauen Oberflächen. Zusätzlich erläutert eine Einleitung die Eigenschaften und Charakterisierungsmöglichkeiten rauer Oberflächen und es wird eine Anwendung der gewonnen Erkenntnisse präsentiert.This thesis deals with the combined light scattering in turbid media and on rough surfaces. The work contains four articles published by the author on the subject of the production of rough surfaces and the interaction between light scattering in turbid media and on rough surfaces. In addition, an introduction explains the properties and characterization possibilities of rough surfaces and an application of the knowledge gained is presented
Dark sequential Z′ portal: Collider and direct detection experiments
No full textWe revisit the status of a Majorana fermion as a dark matter candidate when a sequential Z′ gauge boson dictates the dark matter phenomenology. Direct dark matter detection signatures rise from dark matter-nucleus scatterings at bubble chamber and liquid xenon detectors, and from the flux of neutrinos from the Sun measured by the IceCube experiment, which is governed by the spin-dependent dark matter-nucleus scattering. On the collider side, LHC searches for dilepton and monojet + missing energy signals play an important role. The relic density and perturbativity requirements are also addressed. By exploiting the dark matter complementarity we outline the region of parameter space where one can successfully have a Majorana dark matter particle in light of current and planned experimental sensitivities. © 2018 authors. Published by the American Physical Society. Published by the American Physical Society under the terms of the «https://creativecommons.org/licenses/by/4.0/» Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI. Funded by SCOAP3
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