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Pelaksanaan Sistem Full Day School di SD Islam Mumtaz Cidahu Kuningan Jawa Barat.
Full text linkRima Melati : Pelaksanaan Sistem Full Day School di SD Islam Mumtaz Cidahu
Kuningan Jawa Barat.
SD Islam Mumtaz melaksanakan sistem full day school sejak tahun 2014, namun
dalam kenyataanya belum memenuhi sepenuhnya persyaratan pendirian sekolah
fullday sesuai harapan UUD Perpres No 87 tahun 2017, diantaranya belum
lengkapnya sarana prasarana dan kurangnya tenaga SDM yang professional. Namun
prestasi siswanya dalam hal afektif terlihat sopan, hapalanya terdengar sudah baik,
dan siswanya selalu bertambah tiap tahunya.
Berdasarkan latar belakang masalah tersebut, yang menjadi fokus penelitian ini
adalah sistem pembelajaran full day school di SD Islam Mumtaz Cidahu. Kemudian
fokus penelitian tersebut terinci dalam bentuk pertanyaan-pertanyaan penelitian
sebagai berikut : 1. Bagaimana konsep dasar dan sistem full day school? 2. Bagaimana
kondisi objektif SD Islam Mumtaz Cidahu Kuningan Jawa Barat? 3. Bagaimana
pelaksanaan sistem full day school di SD Islam Mumtaz Cidahu Kuningan Jawa
Barat? Penelitian ini dilakukan dengan bertujuan untuk menjelaskan pelaksanaan
sistem full day school di SD Islam Mumtaz Cidahu Kuningan Jawa Barat.
Penelitian ini menggunakan metode kualitatif, peneliti bertindak langsung sebagai
instrument dan sebagai pengumpul data dari hasil observasi yang mendalam serta
terlibat aktif dalam penelitian. Teknik pengumpulan data dengan observasi,
wawancara mendalam, serta analisis dokumentasi.
Hasil dari penelitian ini adalah; pertama full day school adalah sekolah yang
pelaksanaan pembelajaranya sehari penuh selama 5 hari efektif, dengan proses
pembelajarannya yang memberikan waktu tambahan untuk memperdalam materi
pelajaran agama dan program unggulan lainya. Kedua, sekolah ini didirikan sebagai
wujud kepedulian masyarakat terhadap penanaman nilai-nilai agama pada generasi
penerus. SD Islam Mumtaz berdiri di sebuah area pedesaan, sehingga menjadikan
sekolah ini memiliki suasana yang cukup lengang dan kondusif sebagai kegiatan
pembelajaran SD Islam Mumtaz Cidahu Kuningan Jawa Barat. Ketiga, pelaksanaan
sistem full day di SD Islam Mumtaz memadukan dua kurikulum yaitu kurikulum
kemendikbud dan kurikulum yayasan Imam Nawawi dimapel PAI (tauhid, akhlak,
fiqih, dzikir do‟a, hifdzul hadits, al-qur‟an, halaqoh, tahfidz quran dan membaca arab
gundul). Metode pembelajaranya dibuat mudah menyenangkan
Molecular analysis and protein expression of Ki-67 from formalin-fixed paraffin-embedded serous cystadenoma and serous epithelial ovarian carcinoma specimens / Rima Melati Mat Satar
Full text linkHigh mortality rates in serous epithelial ovarian carcinoma (SEOC) are explained by the fact that majority of the patients present at an advanced stage, with extensively metastatic disease within the peritoneal cavity. Therefore, it is crucial to identify the potential biomarker to detect SEOC that could be used as prognosis. This thesis aimed to provide fundamental knowledge regarding Ki-67 gene expression among SEOC patients in Malaysia. Moreover, the present study also determined gene and protein expression of Ki-67 from formalin-fixed paraffin-embedded (FFPE) tissues of SEOC to normal ovarian tissues. Molecular analysis and protein expression of Ki-67 were investigated by quantitative real-time polymerase chain reaction (RT-qPCR) and immunohistochemistry in 76 FFPE tissues, which consist of 36 normal serous cystadenoma and 40 SEOC specimens. RT-qPCR analysis using Relative Expression Software Tool (REST) 2009 showed a relative normalised expression of Ki-67 gene was up-regulated in SEOC group in comparison to serous cystadenoma by mean factor of 2.251 (standard error, S.E range 0.801 – 6.059, p=0.000). In addition, an independent sample t-test was performed to compare quantification cycle (Cq) values on Ki-67 gene expression. The finding reported that there was a statistically significant difference in Cq values for serous cystadenoma (26.4289±1.95414) and SEOC (25.4513±2.17097), where p=0.043. Furthermore, there was also a statistically significant difference in Cq values between low-grade (26.5393±1.71364) and high-grade SEOC specimens (24.7984±2.18218) where p=0.012. Moreover, chi-square test was also used to study association between International Federation of Gynaecology and Obstetrics (FIGO) stages, FFPE age of serous cystadenoma and SEOC tissue blocks with Ki-67 gene expression. The results showed no association as p>0.05, in which p=0.435, p=0.411 and p=0.312 respectively. On the other hand, protein positivity of Ki-67 was detected in 49 specimens (64.5%), comprising of 9 serous cystadenoma (11.8%), 15 low-grade SEOC (19.7%), and 25 high-grade SEOC (33.0%). Mean Ki-67 labelling index (LI) was higher in SEOC (42.50±27.07) compared to serous cystadenoma (1.99±3.59), and the difference was statistically significant (p=0.000). The difference in mean Ki-67 LI between low-grade SEOC (14.13±13.71) and high-grade SEOC (59.52±16.62) was also shown to be statistically significant (p=0.000). Additionally, FIGO stages of SEOC showed significant association with mean Ki-67 LI (p=0.003). With regards to length of FFPE storage, there was no association between FFPE block tissue age and mean Ki-67 LI among SEOC specimens (p=0.407). However, there was significant association between FFPE block tissue age with mean Ki-67 LI among serous cystadenoma samples (p=0.005). In the present study, amplification and overexpression of Ki-67 suggest the aggressive behaviour of the tumour and poor clinical outcomes. Thus, Ki-67 is an exceptionally cost-effective marker to determine the growth fraction of a tumour cell population
Ki-67 protein as a prognostic indicator in ovarian carcinoma
No full textKi-67 expression is strongly correlated with tumour cell proliferation and growth. It is widely used as a proliferation marker in the routine pathological investigation. The nuclear protein Ki- 67 (pKi67) is recognised prognostic and predictive indicator for the biopsies assessment for cancer patients. Clinically, pKi67 has been revealed to associate with metastasis and the clinical stage of tumours. Furthermore, it has been presented that the expression of Ki-67 is significantly higher in malignant tissues with poorly differentiated tumour cells, as compared with normal tissue. The Ki-67 labelling index plays a vital role as an independent prognostic factor for survival rate, which includes all stages and grade categories. There is an association between the ratios of Ki-67 positive malignant cells and patient survival. This review provides an overview of recent advances in detecting Ki-67 in ovarian carcinoma
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Immuno-positive stained of Ki-67 from formalin-fixed paraffin-embedded serous cystadenoma and serous epithelial ovarian carcinoma specimens / Rima Melati Mat Satar ... [et al.]
Full text linkA vast archive of biopsy and autopsy specimens processed for histological diagnosis exists in pathology laboratory worldwide has potential value for immunohistochemistry studies associated with protein identification such as Ki-67. Determination of cellular activity has been reported to be of a diagnostic with prognostic value used to estimate the number of proliferating cells in ovarian carcinoma. Ki-67 antigen was found to be a reliable diagnostic marker for estimating the Proliferative Index (PI) of a neoplastic lesion by the Mindbomb E3 ubiquitin protein ligase1 (MIB-1 antibody) using immunohistochemistry. However, there is lack of published studies about Ki-67 from serous epithelial ovarian carcinoma (SEOC) in Malaysia. Thus, the purpose of this study is to identify immuno-positive stained associated with protein expression of Ki-67 from serous cystadenoma and SEOC specimens. 76 FFPE specimens which consist of 36 serous cystadenoma and 40 SEOC samples were sectioned and subjected to immuno-histo staining using monoclonal M1B1 antibody. Immuno-positive stained for Ki-67 was analysed by the blinded consultant pathologist. The results were presented as percentage and mean of Ki-67 labelling index (LI) among the samples studied. Protein positivity of Ki-67 was detected in 49 specimens (64.5%), comprising of 9 serous cystadenoma (11.8%), 15 low-grade SEOC (19.7%), and 25 highgrade SEOC (33.0%). Mean Ki-67 LI was higher in SEOC (42.50±27.07) compared to serous cystadenoma (1.99±3.59), and the difference was statistically significant (p=0.000). This study showed that archive FFPE samples were useful to be used for immunohistochemistry study
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