1,818 research outputs found
Big Web Colors: Analyzing the World Top Sites
No full textColors are obviously important for web sites, but how much? in this paper we try to study the problem of abstracting from the actual content, and analyze if and how colors in images have a higher-level fundamental importance. Focusing on the world top web sites, we collected a large pool (almost two millions) of images, and then investigated the relationships of colors with the attractiveness of a page. Can colors alone boost the success of a page, and in what terms? To answer this question we developed an experiment involving a large number of people, measuring how and how much colors affect a page, abstracting from the content. The results show that, rather surprisingly, colors do have a more fundamental significance that can be decoupled from the underlying shapes. We provide qualitative and quantitative insights on how important colors are, and how they actually impact the success of a site in terms of user perception
Analogical transfer of experience and the misuse of diversification
No full textCentro per la Ricerca Scientifica e Tecnologica, Trent
Sustainable Strategies in the Synthesis of Lignin Nanoparticles for the Release of Active Compounds: A Comparison
No full textThe preparation of nanoparticles represents a powerful tool for lignin valorization, as it combines easy methodologies with high application potential. Different synthetic strategies and various lignin sources have been employed in the process. However, the great variability in the lignin structure prevents a direct comparison of the so far reported lignin nanoparticles (LNPs), especially as regards their physicochemical and functional properties. To this purpose, two green protocols, that is, solvent-antisolvent and hydrotropic, were optimized and used to generate LNPs from the same softwood kraft lignin. The nanomaterials were fully characterized to extrapolate structure/property relationships and reveal any differences in the mechanism of self-assembly. Furthermore, tests on methylene blue entrapment capacity and release behavior at two different pH values (2.0 and 7.4) evidenced a clear dependence on the LNPs characteristics and thus on the strategy adopted for their production
Recuerdos de Massimo.
No full textEl presente ensayo recuerda la rica relación personal e intelectual entre Massimo Pavarini e Iñaki Rivera Beiras desde que el segundo conoció siendo muy joven a Pavarini. En ese sentido, el trabajo recuerda los inicios de su fecunda relación en la ciudad de Bologna cuando Iñaki Rivera acudía a presentar a Massimo Pavarini los desarrollos de lo que sería su tesis doctoral. Las contribuciones de Pavarini al proceso de aprendizaje de Rivera, en el terreno de una epistemología crítica en la penología contemporánea, son analizados como un homenaje a la memoria y a la obra del autor italiano, tras su fallecimiento en septiembre de 2015.This paper recalls the rich personal and intellectual relationship between Massimo Pavarini and Iñaki Rivera Beiras. In that sense , the work recalls the beginning of his fruitful relationship in the city of Bologna when Iñaki Rivera came to present Massimo Pavarini’ developments in what would be his PhD thesis. Pavarini contributions to the learning process of Rivera, on the ground of a critical epistemology in contemporary penology , are analyzed as a tribute to the memory and to the work of Italian author, after his death in September 2015 .El presente ensayo recuerda la rica relación personal e intelectual entre Massimo Pavarini e Iñaki Rivera Beiras desde que el segundo conoció siendo muy joven a Pavarini. En ese sentido, el trabajo recuerda los inicios de su fecunda relación en la ciudad de Bologna cuando Iñaki Rivera acudía a presentar a Massimo Pavarini los desarrollos de lo que sería su tesis doctoral. Las contribuciones de Pavarini al proceso de aprendizaje de Rivera, en el terreno de una epistemología crítica en la penología contemporánea, son analizados como un homenaje a la memoria y a la obra del autor italiano, tras su fallecimiento en septiembre de 2015
America aforistica
No full textA discussion of aphoristic writing by American authors, 18th-century to 20th-century
Early complication of a subtrochanteric periprosthetic fracture following hip resurfacing. Is varus healing acceptable? A case report and literature review
No full textThe increase in the incidence of osteoarthritis of the hip (coxarthrosis) in young patients with high functionality requirements and the development of new materials in the last twenty years have resulted in an increase in the number of surgeries involving hip resurfacing procedures. There has also been an increase in associated periprosthetic fractures, which currently occur in 1%-2% of cases. According to the medical literature, fractures of this type can be treated conservatively, using reduction and synthesis or through prosthetic revision
Effective anti-tumor immunomodulatory properties of zoledronic acid
No full textIntroduction. Zoledronic acid (Zol) is the most potent aminobisphosphonates clinically available. Preclinical in vivo data suggest that it modulates the development of bone disease, decreases tumor burden with a direct anti-cancer activity, and reduces the migration and the metastatic invasion of cancer cells. Zol efficacy in anti-cancer adjuvant therapy also rests on its anti-angiogenic properties and ability to expand gamma/delta T cells, both in vitro and in vivo. The published data thus far
available concern murine models of transplanted tumors. Present work was made to assess Zol immune-mediated activity in impairing spontaneous carcinogenesis in a transgenic mouse model. Materials and Methods. To asses Zol anti-tumor and immunomodulant properties, BALBneuT mice were treated with 16 administrations of 100 μg/Kg of Zol divided into four courses of a single weekly injections for four weeks followed by a three weeks rest. Zol administration was started when mice were 7 weeks old and therefore when all the 10 mammary glands display
a widespread atypical hyperplasia. Zol was administered intravenously (i.v.) or into the mammary pad (i.mam.). Mice were evaluated for: 1) tumor onset, 2) tumor multiplicity and 3) overall survival. Results. Data obtained from these first experiments have shown that a similar significant tumor growth impairment was evident in mice receiving Zol administered i.v. or i.mam. Preliminary results have demonstrated Zol capacity to induce a significant increase in the percentage of gammadelta
T cells in the spleen and in the lymphonode of Zol-treated mice. Even more importantly, data obtained in IFNg knocked out -NeuT mice have shown that Zol capacity to delay tumor onset and growth and to improve NeuT-mice survival is strictly dependent on the presence of IFNgamma, which is a well known mediator of innate and adaptive immune responses. Zol immune-mediated anti-tumor properties are further and even more convincingly supported by the evidence that NeuT mice knocked-out for the gene encoding for the Fcg receptor (FcgR-KO NeuT) and NeuT mice knocked-out for the gene encoding for the perforin (PF-KO NeuT) did not benefit of Zol anti-tumor action. Conclusions. All together, these data show for the first time that Zol in vivo antitumor functions at least partially relies on broad immunomodulant properties, involving cellular and humoral immunity
Predoni a casa nostra e il geografo solidale: Massimo Quaini tra terra e acqua
No full textIn accordance with the main goals of this collection of essays in honour of Massimo Quaini, the text focuses on a peculiar character of the Ligurian geographer’s sensibility, his attention to landscape protectionresearch activity developed in the context of the humanistic geography. Starting from a personal narrative based on his own reminiscences and neglected memories, the author tries to shed light on the relationships between civil commitment and cultural reflection which characterize environmental sensitivity, bringing together his interests with Quaini’s emotional geographies. Finally, some of Quaini’s everyday practicalities are highlighted as the easiest doorway to improve the cognitive procedures of cultural geography
Is Felix Salten the author of the Mutzenbacher novel (1906)? Yes and no
No full textJosefine Mutzenbacher oder die Geschichte einer Wienerischen Dirne von ihr selbst erzählt, published in Vienna in 1906, represents one of the most fascinating cases of attribution of authorship in German literature. Although Josefine Mutzenbacher is usually attributed to Felix Salten, the author of the world-famous Bambi (1923), the novel’s authorship has never been confirmed, and many other candidates have been named as potential authors. Among them is Arthur Schnitzler, who published Reigen, a cycle of amorous adventures in Viennese society, in 1903. Some scholars, instead, have attributed the novel to such lesser-known writers as Ernst Klein and Willi Handl. The controversy surrounding the authorship of Josefine Mutzenbacher was the starting point for our stylometric analyses, and our results help to answer some unresolved questions in a debate that has lasted for more than 100 years. The analyses were performed using the R package Stylo, which enables an efficient application of Burrows’ Delta and its variants. Focusing on both the entire text and on the final pages, two different types of analysis were carried out: one combines 1200 different stylometric methods to compare the candidate authors Salten, Schnitzler, Bahr, Altenberg, Hofmannsthal, Klein and Handl; the other verifies the attribution using the ‘impostors’ method. The results show that the most probable author is Felix Salten, while none of the candidates could be identified as the author of the final pages, confirming the hypothesis that the text was left unfinished by Salten and completed by an as-yet-unidentified ghost-writer
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