12 research outputs found
Análise do valor agregado para modelagem da informação da construção no serviço de alvenaria
Get PDFOrientador: Prof. Dr. Sergio ScheerDissertação (mestrado) - Universidade Federal do Paraná, Setor de Tecnologia, Programa de Pós-Graduação em Engenharia Civil. Defesa : Curitiba, 28/03/2022Inclui referênciasResumo: A indústria da construção civil está caminhando para uma maior adoção de tecnologias na busca de novas práticas a fim de melhorar sua competitividade, pois ainda possui suas fases segregadas ocasionando entre outros a falha no fluxo de informação. A utilização da modelagem da informação da construção ou BIM na construção traz vantagens na obtenção de dados que poupam tempo e dinheiro. Na obra há possibilidade de utilização como canal direto para enviar feedback de informações. Com o objetivo de criar um método para controle de execução a partir da análise do valor agregado (EVA) com a utilização de modelos BIM, a pesquisa foi baseada na metodologia da Design Science Research (DSR) e proposta em três fases (ciclos de rigor, de relevância e de design). Para o desenvolvimento do artefato foi feita uma revisão da literatura como embasamento teórico e coleta de dados em uma construtora. A avaliação do artefato foi realizada de forma cíclica durante seu desenvolvimento por testes funcionais e de forma final por simulação que serviu como experimento controlado para obter a evidência do cumprimento de integração do fluxo de informações, facilidade de uso e utilidade. Os resultados encontrados demonstraram que a utilização do modelo com visão operacional facilita a integração com os processos de planejamento e controle, possibilitando automatizar a coleta de dados na obra para o controle de medição e obter índices de desempenho do empreendimento.Abstract: The civil construction industry is moving towards a greater adoption of technologies in the search for new practices in order to improve its competitiveness, as it currently has its phases segregated, causing, among other things, a failure in the flow of information. The use of building information modelling or BIM in construction has advantages in obtaining data that save time and money. In the site it can be used as a direct channel to send information feedback. In order to creating a method for execution control from the earned value analysis (EVA) using BIM models, the research was based on the methodology of Design Science Research (DSR) and proposed in three phases (cycles of rigor, relevance and design). For the development of the artifact, a literature review was made as a theoretical basis and data collection in a construction company. The evaluation of the artifact was carried out cyclically during its development by functional tests and finally by simulation that served as a controlled experiment to obtain evidence of compliance with information flow integration, ease of use and usefulness. The results showed that the use of the model with an operational view facilitates the integration with the planning and control processes, making it possible to automate the data collection in the site for the measurement control and obtain performance indexes of the enterprise
As As cores do suicídio em O meu amigo pintor de Lygia Bojunga
No full textThis paper focuses on the theme of suicide in children's and young adult literature, more specifically on the book O meu amigo pintor (1987) by the Brazilian writer Lygia Bojunga. The book raises two complex debates: the pejorative and questionable position of juvenile children's literature, inferior and devalued in the literary and academic system; and suicide, an interdiction shrouded in taboos and myths in the universe of psychology. Bojunga creates a story that gives the child protagonism as being able to understand the world, death, mourning in their reality, without euphemism or mediators, using literature as a space for dialogue for any topic and age group. And, on the other hand, the author also makes suicide the central theme between rawness and poetic, which are not mutually exclusive in Bojunga's work. The Brazilian writer seeks to deconstruct, one by one, the myths surrounding the theme of voluntary death and the common sense that silences suicide and empties its meaning. Bojunga brings to the theme new colors, nuances, perceptions through the children's world, by opting for a sensitive and honest attitude towards the subject. The book deals with topics such as moral and religious condemnation, the romanticization of suicide and its pathologization. In order to analyse the way in which the author conducts her reflection, we review the studies of Albert Camus, Karl Marx, A. Alvarez and Ana Maria Feijoo.Este trabajo se centra en la temática del suicidio en la literatura infantojuvenil, más específicamente en el libro O meu amigo pintor (1987) de la escritora brasileña Lygia Bojunga. El libro suscita dos complejos debates: la posición peyorativa y cuestionable de la literatura infantil y juvenil, considerada inferior y desvalorizada en el sistema literario y académico; y del suicidio, un tópico envuelto por tabúes y mitos en el universo de la psicología. Bojunga crea una historia que da protagonismo al niño como ser capaz de entender el mundo, la muerte, el luto en su realidad, sin eufemismos o mediadores, instrumentalizando la literatura como espacio de diálogo para cualquier tema y rango de edad. Por otro lado, la autora también sitúa el suicidio como tema central, entre la crudeza y lo poético, que no son excluyentes en esta obra de Bojunga. La escritora brasileña busca deconstruir todos los mitos que circundan el tema de la muerte voluntaria y el sentido común que silencia el suicidio y que vacía su significado. Bojunga aborda el tema con nuevos colores, matices, percepciones a través del mundo infantil, al optar por una postura sensible y honesta delante del asunto. El libro trata tópicos como la condena moral y religiosa, la romantización y patologización del suicidio. Para analizar la manera con que la autora conduce su reflexión, rescatamos los estudios de Albert Camus, Karl Marx, A. Alvarez y Ana Maria Feijoo.Este trabalho se concentra na temática do suicídio na literatura infantojuvenil, mais especificamente no livro O meu amigo pintor (1987) da escritora brasileira Lygia Bojunga. O livro suscita dois complexos debates: a posição pejorativa e questionável da literatura infantil e juvenil, inferiorizada e desvalorizada no sistema literário e acadêmico; e do suicídio, um interdito envolto por tabus e mitos no universo da psicologia. Bojunga cria uma história que dá protagonismo à criança como ser capaz de entender o mundo, a morte, o luto na sua realidade, sem eufemismo ou mediadores, instrumentalizando a literatura como espaço de diálogo para qualquer tema e faixa etária. E, por outro lado, a autora também faz com que o suicídio seja o tema central entre a crueza e a poeticidade, que não são excludentes nesta obra de Bojunga. A escritora brasileira busca desconstruir, um por um, os mitos que circundam o tema da morte voluntária e o senso comum que silencia o suicídio e que esvazia o seu significado. Bojunga traz ao tema novas cores, nuances, percepções através do mundo infantil, ao optar por uma postura sensível e honesta diante do assunto. O livro trata de tópicos como a condenação moral e religiosa, a romantização do suicídio e patologização do mesmo. Para analisar a maneira com que a autora conduz a sua reflexão, resgatamos os estudos de Albert Camus, Karl Marx, A. Alvarez e Ana Maria Feijoo
Entre Céus e Terras, Romance e Relato: a representação da natureza brasileira por Visconde de Taunay
No full textO presente trabalho tem por objetivo discutir, no contexto do Romantismo brasileiro, aspectos relacionados à representação da natureza em duas obras de Visconde de Taunay (1843-1899) – Inocência (1872) e Céus e Terras do Brasil (1882) – o primeiro um romance sertanejo, o segundo um relato de viagem. Pretende-se explorar como a técnica do registro, ou seja, a construção da paisagem pelo viajante interfere no trabalho do ficcionista, tendo em mente a equivalência muitas vezes estabelecida entre natureza e paisagem, e suas implicações na construção de uma perspectiva literária sobre o mundo natural do Brasil. Além disso, é importante entender a tradição de viagem – já que Taunay era um viajante – não apenas como produtora de conhecimento científico, mas também de impressões esteticamente válidas para os propósitos nacionais. Anne Cauquelin afirma em A invenção da paisagem que “as palavras podem mentir; a imagem, por seu lado, parece fixar o que existe” (2007, p.93), isto é, o que vemos acaba fixando-se com mais facilidade ao nosso imaginário. Taunay, portanto, parece utilizar desse “poder da imagem”, já que sua escrita se volta para o elemento visual, com grande predominância de descrições construídas a partir de referências à linguagem do desenho e da pintura, e mesmo sua narrativa se traduz em termos plásticos, ecoando aqui Antônio Cândido. A natureza observada e traduzida por Taunay é transformada em paisagem, já que se constrói uma sensação, diante das suas descrições, que nos remete a observações de quadros/cenas, ou seja, o mundo natural limitado a um enquadramento, totalmente organizado e ornado. Propõe-se um estudo que consiga averiguar a representação da natureza nas obras de Visconde de Taunay, tendo em vista a relação de trânsito textual entre os relatos de viagens e o seu romance no processo de construção de uma paisagem brasileira. Além disso, convém considerar aspectos da ciência romântica que são importantes para a compreensão das obras do autor estudado, uma vez que são colocados em relação o estético e o empíricoCoordenação de Aperfeiçoamento de Pessoal de Nível SuperiorThis dissertation aims to discuss, within the context of Brazilian Romanticism, aspects related to the representation of nature in two works by the author Visconde de Taunay (1843-1899) – Inocência (1872) and Céus e Terras do Brasil (1882) – the first, a “sertanejo” novel, and the second, a travel report. It is intended to explore how the register technique, that is, the construction of the landscape by the traveler interferes in the work of the fiction writer, keeping in mind the equivalence established between nature and landscape, and its implications in the construction of a new literary perspective on Brazil’s natural world. Moreover, it is important to understand the tradition of the voyage – since Taunay was a voyager – not only as a producer of scientific knowledge, but also of aesthetically valid impressions for national purposes. Anne Cauquelin affirms in A Invenção da Paisagem that “words can lie; the image, on the other hand, seems to fixate what already exists” (2007, p. 93, free translation), which means that what we just saw ends up fixating it selfmore easily in our imaginary. Taunay, therefore, seems to use this “power of the image”, as his writing turns to visual elements, dominated by descriptions constructed from references to the languages of drawing and painting, and even his narrative translates itself in to visual terms, with Antônio Cândido being echoed here. The nature observed and translated by Taunay is transfored into landscape, since from his descriptions one may feel as if observing a painting or a scene, which means the natural world is limited to a framework, fully organized and ornate. The purpose of this thesis in to enamine the representation of nature in the works of Visconde de Taunay, keeping in mind the relation of textual transit between the travel reports and his novel in the process of constructing a Brazilian landscape. Furthermore, I shall also consider aspects of romantic science that are important to the understating of the author’s works in question, once they are put in relation with the aesthetics and the empirical92f
Reputation and Sex in the City: governance, women, and paid sex in Newark, New Jersey
No full textThis work investigates the relationship between governance and sex workers in Newark, New Jersey, and what that interaction can teach us about community conflict and sex worker organizing around the issue. The theme of sexuality, particularly sex work, has been mostly disregarded in the city, seen more as a haven for violent crime and racial conflict. This investigation is then designed to affirm Newark as a space worthy of diverse knowledge production by shedding light on the intricate ways women’s – cis and trans – sexualities exist and are managed in the urban space by community, social, and legal forces. Such historical recollection goes from Newark’s foundation until current times, capturing the most important developments in the field, as well as recent organizational practices of organized sex workers opposing whorephobia and respectability politics while trying to survive in a changing urban environment. Therefore, methodologically, this work relies on critical sexuality studies while delving into archival research, participant observation with the sex worker-led organizations New Jersey Red Umbrella Alliance (NJRUA) and Best Practices Policy Project (BPPP), and semi-structured interviews with current and retired Newark sex workers. The present exploration contributes to new forms of looking into municipal politics, the creation and materialization of ideal citizens, as well as organizational/activist initiatives to counteract idealized visions of the city and its citizens. By analyzing these dynamics, we observe how we – as urban constituencies aiming to belong in communities – build and aim to maintain or disrupt reputations encompassing specific ways we live – and mostly, seem to live – our sexualities.Ph.D.Includes bibliographical reference
Por que planejar: o testamento como meio de sucessão
Get PDFAbstract: The Constitution guarantees the civil right to inheritance, the succession process of which begins with death. The lack of succession planning can result in an arduous, conflicting and financially burdensome task for the heirs. That said, some advantages of carrying out succession planning include, for example, the reduction of legal disputes, the prevention of emotional distress, the reduction of financial costs and the preservation of assets. In turn, succession planning facilitates the transfer of assets, avoids family conflicts and promotes well-being among the heirs. In addition, it allows the testator to have control over the distribution of his assets, ensuring the autonomy of the private will of his decisions, comfort and stability for his family and loved ones after his death. From this perspective, this study analyzes testamentary succession planning, considering the economic, social and procedural aspects. The methodology used was qualitative research based on a bibliographic review of doctrines, legislation and scientific articles. It is important to conclude that testamentary succession planning, when carried out under the guidance of a qualified professional, is a rational and necessary act that contributes to the social and economic development of the author of the inheritance, guaranteeing the preservation of the assets and promoting family peace for him and his heirs.
Keywords: Succession planning; Benefits; Testament; Economy; Conflict prevention.A Constituição da República Federativa do Brasil e o Código Civil regulamentam o direito a herança, cujo processo de sucessão se inicia com a morte do autor da herança. Logo, a falta de planejamento sucessório pode resultar em uma tarefa árdua, conflituosa e financeiramente onerosa para os herdeiros. Assim, ao realizar o planejamento sucessório, muitos desses dilemas podem ser evitados, como por exemplo, a redução de litígios judiciais; a prevenção de desgastes emocionais; a diminuição de custos financeiros; a preservação do patrimônio; a transferência de bens, além de evitar os conflitos familiares. O ato de perfectibilizar o planejamento sucessório, permite ainda, que o testador tenha controle sobre a distribuição de seus bens, assegurando a autonomia da vontade privada de suas decisões, equilíbrio e estabilidade para seus familiares e entes queridos após sua morte. Nesta perspectiva, este estudo analisa o planejamento sucessório testamentário, considerando os aspectos econômicos, sociais e processuais. A metodologia utilizada foi de pesquisa qualitativa baseada em revisão bibliográfica de doutrinas, legislações e artigos científicos. Quanto aos resultados, esses apontaram que o planejamento sucessório testamentário, quando elaborado sob a orientação de um profissional qualificado, torna-se um ato benéfico e profícuo, que contribui para o desenvolvimento social e econômico do autor da herança, garantindo a esse e seus herdeiros, a preservação do patrimônio e promovendo a paz familiar
Hypoxys offuscatus Nunes & Campos & Mendonca & Cunha & Fernandes 2020, comb. nov.
No full text<i>Hypoxys offuscatus</i> (Breddin, 1907) comb. nov. <p>(Figs. 7 A–E; 19 A–B; 21)</p> <p> <i>Edessa offuscata</i> Breddin, 1907: 332; Kirkaldy, 1909: 368 (catalog)</p> <p> <i>Edessa rimata</i> Breddin, 1907: 338; Kirkaldy, 1909: 368 (catalog) <b>syn. nov.</b></p> <p> Lectotype male. <i>Edessa offuscata.</i> Brasil, Pebas (SDEI). Designated by Gaedike (1971:94). Examined.</p> <p> Lectotype female. <i>Edessa rimata.</i> Peru, Iguapo (SDEI). Designated by Gaedike (1971:97, by use of “ Holotypus ”). Examined.</p> <p> <b>Material examined. PERU. Loreto:</b> ♀ Iquitos, Amazon River, II–21–1927, H. Bassler (USNM); ♂ ♀ Confl. De los Rios Zamur e Yahuasyacu, II–80, J. Becker leg. <i>Edessa rimata</i> Breddin, 1907 Comp. w. TYPE Fernandes, JAM 1999, <i>Edessa offuscata</i> Breddin, 1907 Comp. w. TYPE Fernandes, JAM 1999. (RMNH).</p> <p> <b>Measurements.</b> total length: 17.2–19.0; head length: 2.3; head width: 3.4–3.6; pronotal width: 11.0–11.3; abdominal width: 9.6–10.3; length of antennal segments. I: 0.9–1.0; II: 2.4; III: 1.3–1.4; IV: 5.7; V: 6.3; interocular distance: 1.6–1.7; scutellum length: 8.4–9.0; scutellum width: 6.2–6.6; pronotal length: 3.6–3.9.</p> <p> <b>Diagnosis.</b> Anterolateral margin of pronotum with solid black stripe reaching all its extension. Cicatrices with dark brown punctures delimiting anterior sulci (Fig. 19A). Anterolateral margin with few dark punctures. Male (Fig. 7 A–C). Pygophore with dorsal rim widely excavated (Fig. 7A). Superior process of genital cup small, arrow-headshaped, adjacent to dorsal rim (Fig. 7B). Paramere elongated, shank triangular (cross section) due to a conspicuous carina on inner side ending before enlarged part; head of the paramere spatulate (Fig. 7B). Proctiger with laterodorsal tufts of setae widely separated by medial ridge; posterior face pentagonal, flat (Fig. 7B). Ventral rim with expansions rounded, wide, tumid, well-projected, clearly surpassing level of posterolateral angle in ventral view (Fig. 7C); base of each expansion with a conspicuous transverse carina. Female (Fig. 7D). Gonocoxites 8 with posterior margin sinuous, inner angle rounded projected posteriorly reaching gonocoxites 9; sutural border with elliptic, short excavation on posterior half. Gonapophyses 8 exposed.</p> <p> <b>Comments.</b> <i>Edessa offuscata</i> and <i>E</i>. <i>rimata</i> were described by Breddin (1907). The author considered <i>E</i>. <i>rimata</i> related to <i>E</i>. <i>trabecula</i> and <i>E</i>. <i>offuscata</i> close to <i>E</i>. <i>quadridens</i> and <i>E</i>. <i>boerneri</i>. However, these similarities are based only on the external morphology of the species. Females of <i>H. offuscatus</i> have inner angles of gonocoxites 8 more protruding and sutural border less excavated (Fig. 7D) than <i>H. boerneri</i> (Fig. 2D); both species have posterior margin of gonocoxites 8 sinuous while <i> <i>H. quadriden</i> s</i> has posterior margin arched (Fig. 1D). Males of <i>H. offuscatus</i> and <i> <i>H. quadriden</i> s</i> are very similar and can be separated by subtle characteristics like paramere more robust and dorsal rim more excavated in <i>H. offuscatus</i> (Fig. 7B and 1B); more obvious distinctive characteristic is the expansion of ventral rim more developed and rounded in <i>H. offuscatus</i> (Fig. 7C) than in <i> <i>H. quadriden</i> s</i> (Fig. 1C).</p> <p> <b>Distribution (Fig. 21).</b> PERU: Loreto.</p>Published as part of <i>Nunes, Benedito Mendes, Campos, Lourival Dias, Mendonca, Maria Thayane Da Silva, Cunha, Eduardo Victor De Paiva & Fernandes, Jose Antonio Marin, 2020, Revision of Hypoxys Amyot & Serville, 1843 stat. rest. (Heteroptera Pentatomidae), pp. 401-441 in Zootaxa 4742 (3)</i> on pages 416-418, DOI: 10.11646/zootaxa.4742.3.1, <a href="http://zenodo.org/record/3677869">http://zenodo.org/record/3677869</a>
Hypoxys subrastratus Nunes & Campos & Mendonca & Cunha & Fernandes 2020, comb. nov.
No full text<i>Hypoxys subrastratus</i> (Bergroth, 1891) comb. nov. <p>(Figs. 11 A–E; 19 I–J; 22)</p> <p> <i>Edessa subrastrata</i> Bergroth, 1891: 233; Lethierry & Severin, 1893: 195 (catalog); Kirkaldy, 1909: 165 (catalog)</p> <p>Lectotype female. Minas Gerais, Brasil (MNHN). Examined.</p> <p> <b>Material examined.</b> <b>BRAZIL. Pará:</b> ♀ Acará, Unamurú, III–66, L. Gomes leg. (RMNH); <b>Maranhão:</b> ♀ São Luís, AL 35–10359, 05–X–1984, A. Brisolla col. (IBSP); <b>Goiás:</b> ♂ Jataí, Faz. Aceiro, X–1962, Exp. Dep. Zool. (MZUSP); ♂ Corumba, Fazenda Monjolinho, 24–VI–1942, F. Lane (MZUSP); ♂ Campinas, Dez–1935, Spitz col. (MZUSP); <b>Minas Gerais:</b> ♀ Varginha, I–1954, S. A. Matos, <i>Edessa subrastrata</i> Bergroth, 1891 Fernandes J. A. M. 1999 Comp. w. TYPE. (FEM); <b>São Paulo:</b> ♀ 27–XII–1997, Fernandes, J. A. M. <i>Edessa subrastrata</i> Bergroth, 1891 Fernandes, J. A. M. 1999 Comp. w. TYPE (UFRG); ♂ Dr. MRAZ Collection National Museum Praha, Czech Republic (NMPC); ♀ Barueri, 10–VII–1966, K. Lenko col. (MZUSP); ♂ Penha, 14–III–1943, F. Lane (MZUSP); <b>Santa Catarina:</b> ♂ Nova Teutônia, 300–500 m, 11–1972, 27º11’B, 52º23’L, Fritz Plaumann (UFRG); <b>Rio Grande do Sul:</b> ♂ Porto Alegre, Jardim Botânico, 10–IX–2000, Fortes, N. F. Col. (UFRG); ♀ Pq. F. Est. Turvo, 19–I–1982, S. L. Bonnato, <i>Edessa subrastrata</i> Bergroth, 1891. Fernandes J. A. M. 1999. Comp. w. TYPE (UFRG); <b>ARGEN- TINA.</b> <b>Candelaria:</b> ♂ Missiones Loreto, IX–1955, F. H. Walz. (RMNH); <b>BOLIVIA. La Paz:</b> ♀ Yungas de La Paz, Dec–4–20–1955, 1200–1700m., M. Luiz E. Pena, Collector (USMN); <b>PARAGUAY. Paraguarí:</b> ♂ Parq. Nac. Ybycuí, 23–I–1981, RD Cave colr (USMN); no data: ♂ 8768, 72212 (MZUSP); ♂ 8768, 72213 (MZUSP); ♂ 7952,72442 (MZUSP).</p> <p> <b>Measurements.</b> total length: 14.6–17.2; head length: 2.1–2.3; head width: 3.3–3.6; pronotal width: 9.3–10.6; abdominal width: 7.4–9.1; length of antennal segments. I: 0.7–0.9; II: 0.7–0.9; III: 1.4–1.7; IV: 2.6–2.9; V: 2.7–2.9; interocular distance: 1.8–1.9; scutellum length: 6.8–7.7; scutellum width: 5.2–5.6; pronotal length: 3.3–3.8.</p> <p> <b>Diagnosis.</b> Punctures of anterior part of scutellum not on dark spots (Fig. 19I). Connexivum uniformly green (Fig. 19I). Abdomen ventrally with dark green transverse stripes on intersegmental areas and pseudosutures (Fig. 19J). Pronotum with punctures light brown or concolorous, sparser on disc. Cicatrices of pronotum with concolorous to dark punctures delimiting anterior sulci. Anterolateral margin of pronotum punctured. Scutellum with apex not punctured (Fig. 19I). Black spot of costal margin reaching approximately 1/4 of corial extension. Dorsal surface of abdomen green with lateral margins brown. Connexivum with some few concolorous punctures concentrated in excavated areas (Fig. 19I). Male (Fig.11 A–C). Dorsal rim of pygophore shallowly excavated, with rectangular median notch (Fig. 11A). Inner wall with large tumescence close posterolateral angles (Fig. 11B). Superior process of genital cup elliptic (Fig. 11B). Paramere large, hatchet-shaped; posterior lobe not developed. Proctiger strongly excavated laterally forming a conspicuous dorsal ridge (Fig. 11A,B); dense tuft of setae on lateral excavation; posterior face triangular and small (Fig. 11B). Ventral rim central excavation widely open; expansions small, slightly dorsally bent, not reaching level of posterolateral angle in ventral view (Fig. 11C). Female (Fig. 11D). Gonocoxites 8 posterior margin arched; inner angle rounded slightly projected over gonocoxites 9; sutural border with distal half in “U”. Gonapophysis 8 widely exposed.</p> <p> <b>Comments.</b> Bergroth (1891) related <i>Edessa subrastrata</i> to <i>E. triangularis</i> and <i>E</i>. <i>affinis</i>, but the morphological characteristics pointed by the author are, actually, shared by many species. <i>Hypoxys triangularis</i> is closer to <i>H. subrastratus</i> but is larger and has a smoky stripe on pronotum (Fig. 19E and 19I). <i>Edessa affinis</i> is smaller, its metasternal process has apices of the arms rounded and genitalia from both sexes are quite different from <i>H. subrastratus</i>. The male is described here for the first time.</p> <p> <b>Distribution (Fig. 22).</b> BRAZIL: Pará, Maranhão, Goiás, Minas Gerais, São Paulo, Santa Catarina, Rio Grande do Sul; ARGENTINA: Candelaria; BOLIVIA: La Paz; PARAGUAY: Paraguarí.</p>Published as part of <i>Nunes, Benedito Mendes, Campos, Lourival Dias, Mendonca, Maria Thayane Da Silva, Cunha, Eduardo Victor De Paiva & Fernandes, Jose Antonio Marin, 2020, Revision of Hypoxys Amyot & Serville, 1843 stat. rest. (Heteroptera Pentatomidae), pp. 401-441 in Zootaxa 4742 (3)</i> on pages 423-425, DOI: 10.11646/zootaxa.4742.3.1, <a href="http://zenodo.org/record/3677869">http://zenodo.org/record/3677869</a>
Análises das Demandas Judiciais para aquisição de Medicamentos.
Get PDFThe new challenge for the management of pharmaceutical care is caused by the phenomenon of Judicialization of Health, which has been demanding a differentiated analysis from managers, in order to respond to court orders, avoid the growth of new demands, as well as preserve the principles and guidelines of the System Single Health. The objective was to analyze the profile of court orders for the supply of medicines filed with the courts against public agents in the Municipality of Vargem Grande do Sul, in the years 2010 and 2016. The data were collected through proceedings judged in the first instance, which had the decision already rendered at the time of consultation. The variables analyzed in the processes were related to the process, the author of the sentence, the doctor who prescribed it and the requested treatment. 35 cases were analyzed and it was found that 63% of users are female, all cases had a writ of mandamus as the type of action, 57% were represented by public defenders, with 54% of the defendants being the municipality and the state. It was evidenced that 23% of these lawsuits took place in 2015, 74% of the prescribers of the actions were private physicians and 69% of these requested medicines were not included in the Municipal List of Essential Medicines (REMUME). The study made it possible to highlight the effects that these decisions have on public policies, the distortions that this phenomenon causes and the economic impact that this practice can cause.O novo desafio para a gestão da assistência farmacêutica é provocado pelo fenômeno da Judicialização da Saúde que vêm exigindo uma análise diferenciada dos gestores, afim de responder as ordens judiciais, evitar o crescimento de novas demandas, bem como preservar os princípios e as diretrizes do Sistema Único de Saúde. O objetivo foi analisar o perfil dos mandados judiciais para fornecimento de medicamentos impetrados junto justiça contra agentes públicos do Município de Vargem Grande do Sul, nos anos de 2010 e 2016. Os dados foram coletados por meio de processos julgados em primeira instância, os quais tiveram a decisão já proferida no momento da consulta. As variáveis analisadas nos processos foram referentes ao processo, ao autor da sentença, ao médico que prescreveu e ao tratamento solicitado. Foram analisados 35 processos e verificou que 63% dos usuários são do sexo feminino, todos processos tinham como tipo de ação mandado de segurança, 57% eram representados por defensores públicos, tendo como réu da ação 54% o município e o estado. Foi evidenciado que 23% dessas demandas judiciais aconteceram no ano de 2015, 74% dos prescritores das ações eram médicos particulares e 69% desses medicamentos solicitados não constavam na Relação Municipal de Medicamentos Essenciais (REMUME). O estudo permitiu evidenciar os efeitos que essas decisões têm sobre as políticas públicas, as distorções que esse fenômeno causa e o impacto econômico que esta prática pode ocasionar
Spatial clusters, social determinants of health and risk of COVID-19 mortality in Brazilian children and adolescents: A nationwide population-based ecological study
Get PDFBACKGROUND: Data regarding the geographical distribution of cases and risk factors for COVID-19 death in children and adolescents are scarce. We describe the spatial distribution of COVID-19 cases and deaths in paediatric population and their association with social determinants of health in Brazil. METHODS: This is a population-based ecological study with a spatial analysis of all cases and deaths due to COVID-19 in Brazil among children and adolescents aged 0–19 years from March 2020 to October 2021. The units of analysis were the 5570 municipalities. Data on COVID-19 cases and deaths, social vulnerability, health inequities, and health system capacity were obtained from publicly available databases. Municipalities were stratified from low to very high COVID-19 incidence and mortality using K-means clustering procedures, and spatial clusters and relative risks were estimated using spatial statistics with Poisson probability models. The relationship between COVID-19 estimates and social determinants of health was explored by using multivariate Beta regression techniques. FINDINGS: A total of 33,991 COVID-19 cases and 2424 deaths among children and adolescents aged 0–19 years were recorded from March 2020 to October 2021. There was a spatial dependence for the crude mortality coefficient per 100,000 population in the paediatric population aged 0–19 years (I Moran 0·10; P < 0·001). Forty municipalities had higher mortality rates, of which 20 were in states from the Northeast region. Seven spatial clusters were identified for COVID-19 mortality, with four clusters in the Northeast region and three in the North region. Municipalities with higher social inequality and vulnerability had higher COVID-19 mortality in the paediatric population. INTERPRETATION: The main clusters of risk for mortality among children and adolescents were identified in municipalities in the North and Northeast regions, which are the regions with the worst socioeconomic indicators and greatest health disparities in the country. Our findings confirmed the higher burden of COVID-19 for Brazilian paediatric population in municipalities with higher social inequality and vulnerability and worse socioeconomic indicators. To reduce the burden of COVID-19 on children, mass immunisation is necessary. FUNDING: None
Semi-synthesis of β-keto-1,2,3-triazole derivatives from ethinylestradiol and evaluation of the cytotoxic activity
No full textCoordenaç~ao de Aperfeiçoamento de Pessoal de Nível Superior (CAPES/
Proc. 1732109). Erika V.M. Orozco was supported by a fellowship provided by the Conselho Nacional de Desenvolvimento Científico e
Tecnol ogico (CNPq/140824/2015-4). Andr e L.M. Porto was supported
by a grant 2014/18257-0 and grant 2016/20155-7, S~ao Paulo Research
Foundation (FAPESP) and Conselho Nacional de Desenvolvimento
Científico e Tecnol ogico (CNPq/Proc. 302528/2017-2). This work was
supported by the Coordenaç~ao de Aperfeiçoamento de Pessoal de Nível
Superior - Brasil (CAPES) - Finance Code 001. The author also
acknowledge the Chromatography Group (Instituto de Química de S~ao
Carlos - USP), including Dr. Guilherme M. Titato for the QqToF analysis
(grant 2004/09498-2, S~ao Paulo Research Foundation).Universidade de São Paulo. Instituto de Química de São Carlos. Laboratório de Química Orgânica e Biocatálise. São Carlos, SP, Brasil.Universidade de São Paulo. Instituto de Química de São Carlos. Laboratório de Química Orgânica e Biocatálise. São Carlos, SP, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil.Universidade de São Paulo. Instituto de Química de São Carlos. Laboratório de Química Orgânica e Biocatálise. São Carlos, SP, Brasil.In this study, we report our contribution to the application of the copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction for the synthesis of β-keto-1,2,3-triazole derivatives 3a-f from ethinylestradiol and their application in the inhibition of two human cancer cells lines: human breast adenocarcinoma (MCF-7) and human hepatocellular carcinoma (HepG2). The β-keto-1,2,3-triazole derivates 3a-f exhibited moderate cytotoxic activity for the HepG2 cells with IC50 values of 29.7 μM (3a), 16.4 μM (3b), 17.8 μM (3c), 20.4 μM (3d), 28.1 μM (3e) and 28.2 μM (3f). The semi-synthetic β-keto-1,2,3-triazoles derivatives 3a-f were all characterized by FT-IR, NMR, HRMS and [α]D
