1,720,955 research outputs found
Efficacy of Triamcinolone Acetonide Intraarticular Injection during Remobilization Phase on Arthrogenic Knee Contracture: Experimental Study in Rat Model
No full textIntroduction Joint contracture, defined as a limitation of passive movement in a joint, can
result from long-term immobilization which leads to significant disability. Triamcinolone
Acetonide (TA), a synthetic glucocorticoid, is known for its anti-inflammatory effects and has
been widely used for joint disorders in humans. This study aims to investigate the effectiveness
of TA injections in reducing arthrogenic contracture in rat knee joints during remobilization.
Method This experimental research utilized a posttest only control group design, conducted
from September to October 2023 at the Integrated Laboratory of the Faculty of Pharmacy,
Universitas Sumatera Utara. Adult male Wistar rats aged 8 weeks, weighing 200-300 grams,
were divided into control, saline (NaCl 0.9%), and TA injection groups. Joint immobilization
was induced for 4 weeks to simulate contracture, followed by remobilization and treatment
interventions.
Results Preliminary findings indicate significant variations in passive range of motion
(PROM), microscopic observations of joint capsule length, width, and cell count per field view
across groups. Detailed results and statistical analysis will provide insight into TA's efficacy.
Discussion The discussion likely revolves around the comparison of TA's anti-inflammatory
and anti-fibrotic effects on joint mobility and histological changes within the joint capsule
against control and saline-treated groups. The implications for clinical practice, potential for
reducing contracture during rehabilitation, and limitations of the study are considered.
Conclusion While the full results and conclusion are not covered in the summary, the study
anticipates demonstrating TA's effectiveness in improving joint mobility and reducing the
progression of arthrogenic contracture during the remobilization phase, with potential
applications in clinical settings.63 PagesTesis Magiste
Clinical Outcome Comparison between Open Laminectomy and Biportal Endoscopic Spine Surgery for Lumbar Spinal Stenosis Treatment
No full textIntroduction
Lumbar spinal stenosis (LSS) is a gradual degenerative process occurred in the lumbar spine,
which include facet joints and ligamentum flavum hypertrophy, intervertebral disc herniation,
narrowing of the intervertebral space, and osteophyte formation. Open laminectomy has long
been considered the “gold standard” treatment for decompression of LSS. Technological
advancement such as endoscopic decompression offers a minimally invasive alternative to
traditional open procedure. The biportal endoscopic spine surgery (BESS) allow the utilization
of conventional surgical instruments, thus make it safer than the uniportal method.
Materials & Methods
A prospective analysis of 86 single-level LSS patients treated by BESS or open laminectomy
was performed. There were 27 patients in the BESS group with a mean age of 60.70 ± 3.17
years and 59 patients in the open laminectomy group with a mean age of 61.68 ± 1.11 years.
Oswestry Disability Index (ODI), visual analog scale (VAS) score, and 36-item short-form
health survey (SF-36) were used to assess the primary clinical outcomes. Surgery time, blood
loss, amount of normal saline used, and complications were also reported.
Results
There was no significant difference statistically between BESS and open laminectomy group
in the VAS score, ODI, and SF-36 at 6 months follow-up. Significant difference was found
when comparing procedure duration (156.67 ± 54.14 vs 181.02 ± 31.49 minutes; p = 0.008), blood loss (135.18 ± 45.60 vs 598.30 ± 151.98 mL; p < 0.001), and amount of normal saline
used (11651.85 vs 2483.05 mL; p < 0.001) in BESS and open laminectomy group.
Discussion
The gold standard treatment for LSS is decompression of the neural structure with or without
fusion. Open laminectomy has long been the main method to achieve this goal. On the other
hand, BESS has been improving rapidly in recent years. Multiple studies stated that
endoscopic-assisted decompression has the same efficacy as open laminectomy in the
management of LSS.
Conclusions
BESS for treatment of LSS provides a safe and innovative approach under clear visualization
and wide endoscopic view, which allows better preservation of nerves and spinal structures. It
had the same efficacy as open laminectomy for treatment of lumbar spinal stenosis, while had
the advantages of minimal invasiveness, less duration of surgery, and minimal bleeding.88 PagesTesis Magiste
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Hubungan Antara Ulnar Variance dengan Penilaian Quick Dash Score pada Pasien Fraktur Distal Radius Ekstraartikular di RSUP Haji Adam Malik Medan Periode Januari 2012 Januari 2017
No full textLatar belakang : Fraktur radius distal mewakili seperenam dari semua fraktur pada kasus emergensi. Korelasi antara hasil radiologis dan fungsional setelah fraktur radius distal tetap kontroversial. Penting untuk mengetahui faktor-faktor yang mempengaruhi hasil fungsional setelah pengobatan fraktur radius distal.
Metodologi : Penelitian ini merupakan penelitian pontong lintang yang menilai hubungan antara ulnar variance dengan Quick DASH Score pada pasien fraktur radius distal ekstraartikular di RSUP H. Adam Malik Medan periode Januari 2012 hingga Januari 2017. Ulnar variance dinilai dari rontgen proyeksi PA dan Quick DASH Score diisi oleh pasien sendiri. Data akan diuji dengan sistem berbasis computer dengan menggunakan uji korelasi Spearman.
Hasil :. Dari total 7 subyek sebagai minimal sampel, didapatkan 21 subyek yang diteliti sampai analisa akhir dengan pasien perempuan 7 orang (33,3%) dan laki-laki 14 orang (66,7%) , usia termuda 16 tahun dan usia tertua 59 tahun dengan rerata sebesar 38,19 ± 14,76 tahun, ORIF 20 subyek (perempuan 7 [35%], laki-laki 13 [65%]), SAC sebanyak 1 subyek (laki-laki 1 [100%]). UV 1 sebanyak 4 subyek perempuan dan laki-laki sebanyak 4 subyek. Mean Quick DASH Score 7,77 ± 8,69 median 4,54. Dari uji data dengan menggunakan teknik berbasis komputer, didapatkan bahwa hasil uji P <0.05 artinya terdapat perbedaan hasil yang signifikan dari hubungan antara ulnar variance dengan penilaian Quick DASH Score pada pasien fraktur radius distal ekstraartikular.
Kesimpulan : Ada hubungan antara ulnar variance dengan Quick DASH Score pada pasien fraktur radius distal ekstraartikular di RSUP. Haji Adam Malik Medan pada Januari 2012 hingga Januari 2017.Objective : Distal radius fractures represents one-sixth of all fractures in emergency ward. The correlation between radiological and functional outcomes after distal radius fractures remains controversial. It is important to know the factors that affect functional outcomes after treatment of distal radius fractures.
Material and methods : This research is a cross-sectional study that assesses the relationship between ulnar variance with Quick DASH Score in patients with extra-articular distal radius fractures at RSUP H. Adam Malik Medan from January 2012 to January 2017. Ulnar variance assessed from PA x-rays and Quick DASH Score filled by patients. Data will be tested with computer-based system by using Spearman correlation test.
Results : From a total of 7 subjects as a minimum sample, 21 subjects were studied until the end of the year with female patients 7 (33.3%) and male 14 (66.7%), youngest at 16 years and oldest at 59 years with average 38,19 ± 14,76 years, ORIF 20 patients (female 7 [35%], male 13 [65%]), SAC 1 patients (male 1 [100%]). UV 1 are 4 patients both female and male. Mean Quick DASH Score 7.77 ± 8.69 median 4.54. From the test data using computer-based system it was found that P 0,001 (<0.05) meaning there is significant difference in outcomes between the ulnar variance and the Quick DASH Score assessment in patients extra-articular distal radius fractures.
Discussion : There is a relationship between ulnar variance with Quick DASH Score in patients extra-articular distal radius fractures at the RSUP. Haji Adam Malik Medan from January 2012 to January 2017.Tesis Magiste
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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