31 research outputs found
Estimation of Exterior Parameters of Sensor Combination for Efficient 3D Modeling
No full textISPRS-Commission V Mid-Term Symposium on Close Range Image Measurement Technique -- JUN 21-24, 2010 -- Newcastle upon Tyne, ENGLANDLaser scanning is the latest method to collect 3D spatial data and modelling. It becomes more and more popular in engineering applications such as 3D modeling, deformation analysis, reverse engineering and urban planning. However, laser scanners are not sufficient on their own for 3D surveying and modeling. It should be used together with the photogrammetric data especially in the orientation of point clouds, measurement of the non-scanning areas, and texture mapping. This task needs the combination of range sensor and image sensor. The sensor combination like this is a very efficient and flexible system for close-range measurement applications. Most of the laser scanners include integrated camera but most of them are low resolution and they can not be removed independent from the scanner. Therefore high resolution camera should be mounted to the laser scanner. In this study we consider mounting a camera onto laser scanner and estimating exterior parameters with strong control methods. We also made experimental studies by using exterior parameters.ISPRS CommissScientific and Technological Research Council of Turkey ( TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK); "Foreign Research Scholarship Program" to Cihan ALTUNTAS; Vienna University of Technology; Scientific Research Found of The Selcuk University ( BAP)We would like to thank The Scientific and Technological Research Council of Turkey ( TUBITAK) for the financial support they have provided as a part of "Foreign Research Scholarship Program" to Cihan ALTUNTAS to the carried out this study in Vienna University of Technology. In addition author Cihan ALTUNTAS thanks Scientific Research Found of The Selcuk University ( BAP) to financial support to attend this scientific event
Sedoanalgesia For Endoscopic Retrograde Cholangiopancreatography in a Morbidly Obese Patient
No full textA hierarchical clustering based panel data approach: A case study of regional incentives
No full textThe main objective of this research is to propose a novel approach based on panel data analysis and hierarchical cluster analysis to investigate the determinants of foreign trade deficit and cluster provinces of Turkey. This study has two important contributions into the existing literature. First, the proposed approach uses provinces based panel data. Second, the proposed approach uses structural factors as explanatory variables. The estimates show that the number of patent, trademark, and design granted, the number of incentive documents prepared, fixed investments and employment corresponding to the energy sector and employment in agricultural sector significantly affect foreign trade deficit in provinces of Turkey. Afterward, hierarchical cluster analysis is also utilized based on the results obtained from the panel data analysis. The results of the proposed approach show that provinces of Turkey are clustered into three clusters and Istanbul is the only province forming the first cluster. © 2022 The Author(s
Dexmedetomidine vs midazolam for premedication of pediatric patients undergoing anesthesia
No full textBackground: Dexmedetomidine, an a2-receptor agonist, provides sedation, analgesia, and anxiolytic effects, and these properties make it a potentially useful anesthetic premedication. In this study, we compared the effects of intranasal dexmedetomidine and midazolam on mask induction and preoperative sedation in pediatric patients. Methods: Ninety children classified as ASA physical status I, aged between 2 and 9, who were scheduled to undergo an elective adenotonsillectomy, were enrolled for a prospective, randomized, and double-blind controlled trial. All of the children received intranasal medication approximately 4560 min before the induction of anesthesia. Group M (n = 45) received 0.2 mg center dot kg-1 of intranasal midazolam, and Group D (n = 45) received 1 mu g center dot kg-1 of intranasal dexmedetomidine. All of the patients were anesthetized with nitrous oxide, oxygen, and sevoflurane, administered via a face mask. The primary end point was satisfactory mask induction, and the secondary end points included satisfactory sedation upon separation from parents, hemodynamic change, postoperative analgesia, and agitation score at emergence. Results: Satisfactory mask induction was achieved by 82.2% of Group M and 60% of Group D (P = 0.01). There was no evidence of a difference between the groups in either sedation score (P = 0.36) or anxiety score (P = 0.56) upon separation from parents. The number of patients who required postoperative analgesia was higher in the midazolam group (P = 0.045). Conclusion: Intranasal dexmedetomidine and midazolam are equally effective in decreasing anxiety upon separation from parents; however, midazolam is superior in providing satisfactory conditions during mask induction
Does Treatment with Dexmedetomidine Intra-articularly Improve Postoperative Pain and Rehabilitation after Anterior Cruciate Ligament Reconstruction?
No full textThis study aims to evaluate the analgesic efficacy of dexmedetomidine added to levobupivacaine following anterior cruciate ligament (ACL) surgery. Fifty patients undergoing ACL reconstruction were included. Group DL (dexmedetomidin-levobupivacaine) received 20mL 0.5% levobupivacaine plus 1mL (100 mu g) dexmedetomidine. Group L (levobupivacaine) patients received 20mL 0.5% levobupivacaine plus 1mL saline 10minutes before tourniquet release. A patient-controlled analgesia (PCA) pump was then connected, delivering 0.5mg at every 10minutes and 1-mg morphine and 75-mg diclofenac sodium was used as a rescue analgesic. Postoperative pain was evaluated 0, 2, 4, 6, 12, and 24hours after extubation at rest and during movement. A rehabilitation program was started after surgery. Postoperative continuous passive motion (CPM) starting time, postoperative leg flexion angle, and straight leg lifting time were evaluated for each group. There were no significant differences between the groups in terms of demographic data and operation time. Morphine consumption, analgesic requirements, and visual analogue scale (VAS) assessments were significantly lower in group DL during the 24-hour period after surgery. The time to start CPM in the postoperative period was significantly shorter in group DL. Passive joint flexion angle was significantly higher in group DL. Postoperative straight leg lifting time was significantly shorter in group DL. Adding dexmedetomidine to the intra-articular levobupivacaine provided better postoperative pain control and improved rehabilitation period after ACL surgery
Is the Addition of Dexmedetomidine to a Ketamine-Propofol Combination in Pediatric Cardiac Catheterization Sedation Useful?
No full textPediatric patients undergoing cardiac catheterization usually need deep sedation. In this study, 60 children were randomly allocated to receive sedation with either a ketamine-propofol combination (KP group, n = 30) or a ketamine-propofol-dexmedetomidine combination (KPD group, n = 30). Both groups received 1 mg/kg of ketamine and 1 mg/kg of propofol for induction of sedation, and the KPD group received an additional 1 mu g/kg of dexmedetomidine infusion during 5 min for induction of sedation and a maintenance infusion of 0.5 mu g/kg/h. In both groups, 0.2 mg/kg of propofol was administered as a bolus to maintain a Ramsey sedation score (RSS) greater than 4 throughout the procedure. None of the patients in either group required intubation. In the KP group, one patient required mask ventilation. The chin-lift maneuver needed to be performed for eight patients in the KP group and one patient in the KPD group (p 0.05). The mean recovery time was longer in the KP group (5.86 vs 3.13 min; p < 0.05). Adding dexmedetomidine to a ketamine-propofol combination led to a reduced need for airway intervention and to decreased movement during local anesthetic infiltration and throughout the procedure. The recovery time was shorter and hemodynamic stability good in the KPD group
Severe methanol intoxication due to spirit consumption and magnetic resonance imaging findings İspirto tüketimine baǧli{dotless} ciddi metanol zehirlenmesi ve manyetik rezonans görüntü bulgulari{dotless}
No full textAcute methanol intoxication may result in a wide range of damage to the central nervous system. Most patients are typically admitted to the hospital for several days after methanol ingestion, presenting with visual disruptions, severe acidosis, or both. Rapid diagnosis and treatment are necessary to prevent death and to minimize the neurological sequelae. We want to emphasize the importance of specific MRI findings in a patient, who had drunk a bottle of beer and 70 mL of spirits, and was admitted to hospital after 20 hours, with severe metabolic acidosis and loss of consciousness. A methanol assay was unavailable. © 2013 by Erciyes University School of Medicine
Exploring the Viability of Low-Grade Turkish Clays in the Development of Limestone Calcined Clay Cement (lc3) and Mortars
No full textUnderstanding the variability in raw materials for limestone calcined clay cement (LC3) is crucial for developing standardized protocols and optimizing production for reliable performance. T ; uuml;rkiye, Europe's largest cement producer, has yet to see research focused on LC3 development using local resources. This study, for the first time, focuses on developing LC3 and mortars based on Turkish clays, aiming to address the challenges posed by the geographical variability of raw materials in LC3 research. To improve the sustainability credentials of LC3, abundant low-grade/waste clays from mine tailings (MT) and construction and demolition waste (CDW) were extensively investigated in paste and mortar forms. Each clay was individually analyzed for chemical composition, mineralogy, and physical characteristics through X-ray diffraction (XRD), X-ray Fluorescence (XRF), wet method, thermogravimetric (TG) analysis, and particle size distribution (PSD). Based on the hardness of the raw materials, bulk low-grade/waste-based clays, limestone, and gypsum were hybrid ground to improve particle size distribution and material homogeneity. The viscosity and plasticity of clays from MT and CDW were compared, considering their impact on grindability, consistency and flowability. The consistency, setting time, flowability, and compressive strength of LC3 mixtures were benchmarked against traditional CEM I cement pastes and mortars, as well as LC3 specimens made with high-grade refined kaolin. Life cycle analysis (LCA) was performed to quantify environmental impacts. Each LC3 mixture having low-grade/waste clays met the standards for consistency, setting time, and strength activity index. The results highlight the potential for broader use of lowgrade calcined clays and CDW from T ; uuml;rkiye as practical, sustainable, and competitive alternatives to traditional Portland cement/mortar, significantly reducing the environmental impact.The authors gratefully acknowledge the financial assistance of the Scientific and Technical Research Council of Turkiye (TUBITAK) for the project titled "Development of Limestone Calcined Clay Cement (LC 3) and Mortars with Low Quality Clays from Turkiye" and numbered "123M850". This publication is a part of the master thesis dissertation work by the first author in the Academic Program of Civil Engineering, Institute of Science, Konya Technical University supported by the Scientific Research Projects (BAP) Coordination Office under grant "231004022".Scientific and Technical Research Council of Turkiye (TUBITAK) [123M850]; Scientific Research Projects (BAP) Coordination Office [231004022
β-Escin reduces cancer progression in aggressive MDA-MB-231 cells by inhibiting glutamine metabolism through downregulation of c-myc oncogene
No full text© 2022, The Author(s), under exclusive licence to Springer Nature B.V.Background: The c-myc oncogene, which causes glutamine dependence in triple negative breast cancers (TNBC), is also the target of one of the signaling pathways affected by β-Escin. Methods and results: We sought to determine how c-myc protein affects glutamine metabolism and the proteins, glutamine transporter alanine-serine-cysteine 2 (ASCT2) and glutaminase (GLS1), in β-Escin-treated MDA-MB-231 cells using glutamine uptake and western blot analysis. Cell viability, colony formation, migration and apoptosis were also evaluated in MDA-MB-231 cells in response to β-Escin treatment using MTS, colony forming, wound healing, and Annexin-V assay. We determined that β-Escin decreased glutamine uptake and reduced c-myc and GLS1 protein expressions and increased the expression of ASCT2. In addition, this inhibition of glutamine metabolism decreased cell proliferation, colony formation and migration, and induced apoptosis. Conclusions: In this study, it was suggested that β-Escin inhibits glutamine metabolism via c-myc in MDA-MB-231 cells, and it is thought that as a result of interrupting the energy supply in these cells via c-myc, it results in a decrease in the carcinogenic properties of the cells. Consequently, β-Escin may be promising as a therapeutic agent for glutamine-dependent cancers
