7,268 research outputs found
ADAM SMITH'S OPTIMISTIC TELEOLOGICAL VIEW OF HISTORY
Adam Smith's four-stage theory provides the framework for his writings on history. The fourth stage is the commercial epoch; the culmination of history in this stage is a key component in the conventional interpretation of Adam Smith as a prophet of commercialism. In two historical case studies Smith shows the capacity of commercial society to regenerate itself. This potent capacity suggests that commercial society is inevitable. At a certain point in time it also overcomes the major obstacles to its permanence. Smith's philosophy of history anticipates the end of history views of Kant and Hegel.Political Economy,
How Might Adam Smith Pay Professors Today?
Adam Smith’s proposal for paying professors was intended to induce increased faculty knowledge. If students have imperfect information about what they learn, and universities can only imperfectly measure the input of faculty time in student learning, publications may be used to measure faculty knowledge. If professors’ ability to publish is positively related to their ability to produce student learning, which universities can imperfectly measure, publications may be necessary to attract more able professors. Since research signals faculty knowledge, schools that do not value publications per se could require higher publication standards and pay higher wages than schools that value only publications.
Supplemental Material - Swarm analytics: Designing information markers to characterise swarm systems in shepherding contexts
Supplemental Material for Swarm analytics: Designing information markers to characterise swarm systems in shepherding contexts by Adam J Hepworth, Aya Hussein, Darryn J Reid and Hussein A Abbass in Adaptive Behavior</p
ADAM SMITH'S VIEW OF HISTORY: CONSISTENT OR PARADOXICAL?
The conventional interpretation of Adam Smith is that he is a prophet of commercialism. The liberal capitalist reading of Smith is consistent with the view that history culminates in commercial society. The first part of the article develops this optimistic interpretation of Smith's view of history. Smith implies that commercial society is the end of history because 1) it supplies the ends of nature that he identifies; 2) it is inevitable; and 3) it is permanent. The second part of the article shows that Smith has some dark moments in his writings where he seems to reject completely such teleological notions. In this more civic humanist mood he confesses that commercial society does not supply the ends of nature, nor is it inevitable, nor is it permanent. Both views exist in Smith and the commentator is forced to choose between passages in Smith's work in order to support a particular interpretation of the former's view of history.Political Economy,
Emerging Roles of Cholinergic Receptors in Schwann Cell Development and Plasticity
The cross talk between neurons and glial cells during development, adulthood, and disease, has been extensively documented. Among the molecules mediating these interactions, neurotransmitters play a relevant role both in myelinating and non-myelinating glial cells, thus resulting as additional candidates regulating the development and physiology of the glial cells. In this review, we summarise the contribution of the main neurotransmitter receptors in the regulation of the morphogenetic events of glial cells, with particular attention paid to the role of acetylcholine receptors in Schwann cell physiology. In particular, the M2 muscarinic receptor influences Schwann cell phenotype and the α7 nicotinic receptor is emerging as influential in the modulation of peripheral nerve regeneration and inflammation. This new evidence significantly improves our knowledge of Schwann cell development and function and may contribute to identifying interesting new targets to support the activity of these cells in pathological conditions
The social impacts of the heat–health watch/warning system in Phoenix, Arizona: assessing the perceived risk and response of the public
abstract: Here, 201 surveys were distributed in Metropolitan Phoenix to determine the social impacts of the heat warning system, or more specifically, to gauge risk perception and warning response.Corresponding Author:
Adam J. Kalkstein
Arizona State University
[email protected]
REID BROS, LTD / 101 /STANDARD SONGS / Tonic Solfa and Old Notation Combined_Full Pianoforte Accompaniments.
Title page: "E.T POTTER / Everything Musical / [... SALI]SBURY[?]" [stamp]Box no. 1Reid Bros: 101 Standard Songs; music printItem type: book | Content type: music and text | Counting of pages: page numbersvocal-instrumental score | staff notation; tonic sol-fa notation | voice; piano"Men of Harlech in the hollow, Do ye hear, like rushing billow [...]"March of the Men of Harlech (words by W.[illiam] Duthie); Giordani: Caro Mio Ben; Samuel Lover: Molly Bawn [from “Il Paddy Whack in Italia”]; W.[illiam] H.[erbert] Jude: Silvery Bells (words by W.[illiam] Cartwright-Newsam); Dr W[ilia]m Boyce: Heart of Oak (words by David Garrick); J. Louis Rockliffe and H.[enry] T.[emple] Leslie: The Four Jolly Smiths; Richard Wagner: Star of Eve [“O du mein holder Abendstern" from "Tannhäuser und der Sängerkrieg auf Wartburg”.]; C.M. von Weber: When the thorn is white with blossom (words by S.C.) [Lied der Hirtin]; Samuel Lover: The low back'd car; My love is like a red, red rose (Air "Low down in the broom.") (words by [Robert] Burns); Carl Monteith: Dream of Me (words by Clifton Bingham); Widdicome Fair; Scots wha hae; Kathleen O'Moore; Clement Locknane: I know a little word (words by Geo. Grossmith Jun.); A. Grieg: Love is like sweet briar roses; H. Evan-Jones: Lily of Llanover (words by Cyril Oakes); Henry C.[lay] Work: Marching through Georgia; [John Wall Callcott]: Drink to me only with thine eyes ([words by] Ben Jonson); Claude Melville: Take back thy Gift (words by Edward Oxenford); J.[ohn] L.[iptrot] Hatton: The Lark now leaves his wat'ry Nest (words by sir W.[illiam] Davenant); W.[illiam] H.[erbert] Jude: For King and Country; Fred Whishaw: When all the World is Young (words by Charles Kingsley); Rocked in the Cradle of the Deep; Thomas P.[ayne] Westendore [instead of Westendorf]: Dar's one more ribber for to cross. The Great Jubilee Song (words by James Hosey); James James and Owain Alaw [John Owen]: Land of my Fathers; Gerard F.[rancis] Cobb: Carisbrooke (words by G.[eorgeanne] Hubi Nemcombe; Eliza Cook and John Blockley: Many happy returns of the day; W.[illoughby] H.[unter] Weiss: The Village Blacksmith (words by [Henry Wadsworth] Longfellow); Virginia Gabriel: Cleansing Fires (words by Adelaide Proctor); Henry Bishop: Home Sweet Home ([words by John Howard] Payne); The Campbells are comin'; R.[ichard J.[ohn] S.[amuel] Stevens: Sigh no more, ladies; W. H. Lonsdale: Cupid's Darts; S.[ydney] Nelson: Madoline (Edward J. Gill); Adam Geibel: Wonderland. Fairy Lullaby; Clementine ([words by] Percy Montrose [instead of Montross]); The harp that once thro' Tara's halls; A.[lexander] Hume: Afton Water; Arthur S.[eymour] Sullivan: If doughty deeds my lady please (words by [Robert Cunninghame] Graham of Gartmore); A. Grieg: To Daffodils (from love's litanies) (words by Kenneth Douglas); Claude Melville and W[illia]m Cartwright Newsam: The Angelus; [Friedrich Glück:] The Mill Wheel (“In einem kühlen Grunde”; [words by Joseph von Eichendorff]); Ch.[arles] Gounod: When all was young. Romance from "Faust" (“Si le bonheur à sourer t’invite”); Bonnie Dundee; Claribel [pseudonym of Charlotte Alington Barnard]: Take back the heart ([words by] G. R. Gifford); Julius Benedict: Eily Mavourneen; Julius Benedict: I'm Alone; Arthur [Seymour] Sullivan: A Hymn of the Home-land (words by H.[ugh] R.[eginald] Haweis); Caller Herrin'; C.[harles] Gounod: Serenade ([words by Victor Hugo]); John Peel; Claribel: Come Back to Erin; The wearing of the Green; Claribel: I cannot sing the Old Songs; John Hullah: The Storm. Descriptive song (words by Adelaide Procter); The Blue Bells of Scotland; Julius Benedict: By the Sad Sea Waves ([words by] Alfred Bunn); Henry Russell: A life on the ocean wave (words by E.[pes] Sargent); Mary of Argyle; S.[tephen] C.[ollins] Foster: My Old Kentucky Home; The Keel Row; John Brown's Body. March Song of the American Civil War; W.[illiam] H.[erbert] Jude: On the deep blue sea (words by Clifton Bingham); Alfred Redhead: The North Wind doth blow; Poor Old Joe; Brinley Richards: God bless the Prince of Wales; Auld Lang Syne (words by Robert Burns); Claribel: You and I; Claribel: Milly's Faith; Henry Lamb [pseudonym of George L. Spaulding]: The Volunteer Organist ([words by William B. Gray]); Braham: The Anchor's Weigh'd; John Hoskins: Mollie Malone; J.[ames] Pierpont: Jingle Bells; M.[ichael] W.[illiam] Balfe: Come into the garden Maud ([words by] Alfred Tennyson); Dolores [pseudonym of Ellen Dickson]: Wings (words by W.[illiam] Cartwright-Newsam); Joseph Barnby: Sweet and low (arrangement by W.[illiam] H.[erbert] Jude; [words by] Alfred Tennyson); Alfred G.[eorge] Robyn: Answer? Ballad; Claude Melville: Go forth! O my Spirit. Sacred song (words by W.[illiam] Cartwright-Newsam); Victor Girdlestone [pseudonym of Gustav Krenkel]: Life's Secret (words by A.[nna] L.[aetitia] Barbauld); Annie Laurie ([words by Alicia Ann Scott?]); C.[harles] F. Shattuck: A hundred fathoms deep (words by R.[ichard] Cranshaw); Arthur [Seymour] Sullivan: Orpheus with his Lute (words by [William] Shakespeare); Barbara Allen; Francis Böhr: God Bless our England; Fred Whishaw: Music when soft voices die (words by [Percy Bysshe] Shelley); Claribel: Strangers Yet ([words by Richard Monckton Milnes] Houghton); Love's Mirror (arrangement by A. L.); M.[ichael] W.[illiam] Balfe: When other lips; Anton Strelezki: When twilight comes [original title: Dreams] ([words by] Baroness Porteous); W. Jackson: The Dear little Shamrock ([words by] Oherry); John L.[iptrot] Hatton: Good-bye Sweetheart Good-bye ([words by] Folkestone Williams; J.[oseph] Ascher: Alice, where art thou? ([words by Wellington Guernsey]); Edwin Greene: My Home (words by Clifton Bingham); M.[ichael] W.[illiam] Balfe: Killarney ([words by] E.[dmund] Falconer); Comin; thro' the Rye; [Henry] R.[owley] Bishop: Chime again, beautiful Bells; Francis Böhr: Love's Message (words by Maud Bolton); Within a Mile of Edinburgh Toon; Henry R.[obinson] Allen: Maid of Athens ([words by] Lord Byron); Louis Diehl: Jack's Yarn (words by F.[rederick] E.[dward] Weatherly
Functional Characterization of Muscarinic Receptors in Human Schwann Cells
Functional characterization of muscarinic cholinergic receptors in myelinating glial cells has been well described both in central and peripheral nervous system. Rat Schwann cells (SCs) express different muscarinic receptor subtypes with the prevalence of the M2 subtype. The selective stimulation of this receptor subtype inhibits SC proliferation, improving their differentiation towards myelinating phenotype. In this work, we describe for the first time that human SCs are cholinoceptive as they express several muscarinic receptor subtypes and, as for rat SCs, M2 receptor is one of the most abundant. Human SCs, isolated from adult nerves, were cultured in vitro and stimulated with M2 muscarinic agonist arecaidine propargyl ester (APE). Similarly to that observed in rat, M2 receptor activation causes a decreased cell proliferation and promotes SC differentiation as suggested by increased Egr2 expression with an improved spindle-like shape cell morphology. Conversely, the nonselective stimulation of muscarinic receptors appears to promote cell proliferation with a reduction of SC average cell diameter. The data obtained demonstrate that human Schwann cells are cholinoceptive and that human cultured Schwann cells may represent an interesting tool to understand their physiology and increase the knowledge on how the cholinergic stimulation may contribute to address human SC development in normal and pathological conditions
Cloning, purification and characterisation of human and mouse ADAM 8 sheddase activity
Al-Riyami H. Cloning, purification and characterisation of human and mouse ADAM 8 sheddase activity. Bielefeld (Germany): Bielefeld University; 2006
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