1,720,957 research outputs found

    A paediatric supratentorial primitive neuroectodermal tumour associated with malignant astrocytic transformation and a clonal origin of both components

    No full text
    The case of a 7-year-old boy suffering from a supratentorial primitive neuroectodermal tumour (sPNET) at the age of 5 is presented. The tumour has been characterized by astrocytic areas within the sPNET revealing malignant transformation up to a multiform glioblastoma during the course of the disease. The clonal origin of both tumour components was established by loss of heterozygosity (LOH) analysis. Clinically, the tumour showed an aggressive biological behaviour with two recurrences. We discuss this very rare case and the first description of the clonal origin of distinct and distinguishable tumour components taking into consideration published literature

    Going Beyond Counting First Authors in Author Co-citation Analysis

    Get PDF
    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

    Get PDF
    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

    Get PDF
    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

    Get PDF
    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

    No full text
    Nao informado

    koamabayili/VECTRON-author-checklist: VECTRON author checklist

    No full text
    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used

    Cervikale Rückenmarkstimulation : Methode, Indikationen, eigene Ergebnisse

    No full text
    Die Rückenmarkstimulation ist seit vielen Jahren eine etablierte, invasive Methode der Schmerztherapie und kann in bestimmten Körperbereichen auch zur Verbesserung der Durchblutung dienen. Inzwischen besteht eine interdisziplinäre Leitlinie zur epiduralen Rückenmarkstimulation, bei der es für verschiedene Erkrankungen klare Empfehlungen und Anwendungen dieses Verfahrens gibt. So zum Beispiel für das komplex-regionale Schmerzsyndroms, therapierefraktäre Angina pectoris sowie die periphere arterielle Verschlusserkrankung. Formell ist daher die klinische Aufarbeitung des Therapieverfahrens durch Leitlinien und wissenschaftlicher Literatur sehr gut. Üblicherweise wird bei einer Rückenmarkstimulation von einer thorakalen oder thorakolumbalen Platzierung der Stimulationssonde ausgegangen. Eine Besonderheit bietet die cervikale Stimulation. Sichere Literaturstellen gibt es dazu aber sehr wenige. Meist bilden die Patienten, die eine cervikale Stimulation erhalten hatten, eine Untergruppe, der mit einer thorakolumbalen Stimulation behandelten Patienten, so dass sich, bezüglich dieser speziellen Therapieform keine sicheren Aussagen entwickeln lassen. Wir stellen im Folgenden unser Patientenkollektiv, das bisher größte veröffentlichte, von 30 Patienten vor, die prospektiv eine cervikale Rückenmarkstimulation erhalten hatten. Die Wirkungsweise und Implantationstechniken der Stimulation werden diskutiert und in Zusammenhang mit den bisher veröffentlichten Arbeiten gestellt. Zwischen 2006 und 2011 wurden in der Neurochirurgischen Klinik der Friedrich-Schiller-Universität Jena 36 Patienten mit einem Durchschnittsalter von 56 Jahren für eine cervikale Rückenmarkstimulation evaluiert. Nach entsprechender Testphase, wurde bei 30 Patienten eine Rückenmarkstimulation cervikal implantiert. Die durchschnittliche Schmerzstärke auf der VAS-Skala nach 2 Jahren sank von 8,4 auf 4,6. Eine deutliche Verbesserung der psychischen Verfasstheit konnte dokumentiert werden, ebenso eine Reduktion des Opiatverbrauchs. Eine Komplikationsrate von 33% blieb im durchschnittlichen Bereich. Im Vergleich zur thorakolumbalen Rückenmarkstimulation, erscheint die cervikale Rückenmarkstimulation technisch schwieriger, zeigt aber im vorliegenden Patientenkollektiv keine schlechteren Ergebnisse als die thorakolumbale Implantation und kann genauso in eine schmerztherapeutische Erwägung mit einbezogen werden.vorgelegt von: Rupert ReichartMedizinische Universität Wien, Masterarb., 201
    corecore