89 research outputs found
Assessment of needs and contents of a customized digital tool for retention to care and Medication adherence among pregnant and Breastfeeding women living with HIV/AIDS in Kilimanjaro
Get PDFA Dissertation Submitted in Partial Fulfilment of the Requirements for the Degree
of Master of Science in Public Health Research of the Nelson Mandela African
Institution of Science and Technology, Arusha, TanzaniaRetention in care and adherence to medication among pregnant and breastfeeding women living
with HIV (PBWLH) are crucial for prevention of mother to child transmission (PMTCT) of HIV.
Wide coverage of mobile phones, digital tools, including the use of internet enabled medication
dispensers and short message service (SMS), have been recommended as potential interventions
to improve adherence to medication by PBWLH. The main objective of the study was to
understand the needs and contents for a customized digital tool for retention in care and medication
adherence among PBWLH. A mixed-methods study was conducted from September 2021 to
March 2022 at five health facilities in Kilimanjaro region. Pregnant and breastfeeding women
receiving PMTCT services were included in a survey using a semi-structured questionnaire.
Among the interviewed, twenty breastfeeding women were purposively selected and enrolled to
use an internet enabled Wisepill medication dispenser for one month. They received different types
of SMS reminders for a period of one month and feedback on their adherence patterns was received
after one month using adherence graph from the Wisepill digital tool. Later, exit interviews, in-
depth interviews were conducted to explore needs and contents for a future customized digital
adherence tool. Descriptive analyses for quantitative data and thematic content analyses for
qualitative data were also done. Among 142 women interviewed, 42(30%) were pregnant and 100
(70%) were breastfeeding. A majority of 136 (95%) had access to mobile phones and used SMS
daily, while 90% were interested in receiving reminder messages. Qualitative findings revealed
more insights on reminders’ content and educational SMS. Most people preferred neutral SMS
which does not contain the word “medication”. Health educational SMS content was preferred to
be on breastfeeding, opportunistic diseases, nutrition and entrepreneurship education. Overall,
SMSs were regarded helpful to remind clients on medication time and the medication dispenser
provided them with privacy and safe storage for their medication. Findings from this study will
help to construct useful content for future digital adherence tools to support the health of pregnant
and breastfeeding women living with HIV
Business Organization and Coordination in Marketing Specialty Hogs: A Comparative Analysis of Two Firms from Iowa
Get PDFWe study business organization and coordination of specialty-market hog production using a comparative analysis of two Iowa pork niche-marketing firms.� We describe and analyze each firm's management of five key organizational challenges: planning and logistics, quality assurance, process verification and management of "credence attributes," business structure, and profit sharing.� Although each firm is engaged in essentially the same activity, there are substantial differences across the two firms in the way production and marketing are coordinated.� These differences are partly explained by the relative size and age of each firm, thus highlighting the importance of organizational evolution in agricultural markets, but are also partly the result of a formal organizational separation between marketing and production activities in one of the firms.specialty hogs
Projekt JAI-MARO Waterkrachtcentrale
No full textHet verslag bestaat uit 3 delen: Deel A: vooronderzoek - probleem definitie en inleiding. Deel B: Ondergrondse centrale -Energieberekeningen. Deel C: Ondergrondse centrale -Globale dirnensionering van enige onderdelen.Hydraulic EngineeringCivil Engineering and Geoscience
Can smartphones and tablets improve the management of childhood illness in Tanzania? A qualitative study from a primary health care worker’s perspective
Get PDFThe impact of the Integrated Management of Childhood Illness (IMCI) strategy has been less than anticipated because of poor uptake. Electronic algorithms have the potential to improve quality of health care in children. However, feasibility studies about the use of electronic protocols on mobile devices over time are limited. This study investigated constraining as well as facilitating factors that influence the uptake of a new electronic Algorithm for Management of Childhood Illness (ALMANACH) among primary health workers in Dar es Salaam, Tanzania.; A qualitative approach was applied using in-depth interviews and focus group discussions with altogether 40 primary health care workers from 6 public primary health facilities in the three municipalities of Dar es Salaam, Tanzania. Health worker's perceptions related to factors facilitating or constraining the uptake of the electronic ALMANACH were identified.; In general, the ALMANACH was assessed positively. The majority of the respondents felt comfortable to use the devices and stated that patient's trust was not affected. Most health workers said that the ALMANACH simplified their work, reduced antibiotic prescription and gave correct classification and treatment for common causes of childhood illnesses. Few HWs reported technical challenges using the devices and complained about having had difficulties in typing. Majority of the respondents stated that the devices increased the consultation duration compared to routine practice. In addition, health system barriers such as lack of staff, lack of medicine and lack of financial motivation were identified as key reasons for the low uptake of the devices.; The ALMANACH built on electronic devices was perceived to be a powerful and useful tool. However, health system challenges influenced the uptake of the devices in the selected health facilities
Implementasi Alokasi Dana Desa dalam Pemberdayaan Masyarakat Di Desa Mudung Darat Kecamatan Maro Sebo Kabupaten Muaro Jambi
Get PDFAccording to the results of observations made by the author in the village of Mudung Darat, Maro Sebo District, Muaro Jambi Regency, the management of village funds, especially the Village Fund Allocation, has not been implemented optimally, especially in the planning and implementation stages of the village fund allocation. This study aims to determine and analyze the Implementation of Village Fund Allocation in Community Empowerment in Mudung Darat Village, Muaro Jambi Regency, to identify and analyze the constraints of Village Fund Allocation Implementation in Community Empowerment in Mudung Darat Village, Muaro Jambi Regency and to identify and analyze the efforts made to overcome the obstacles in implementing Village Fund Allocation in Community Empowerment in Mudung Darat Village, Muaro Regency. This type of research used in this paper is empirical juridical research. The implementation of ADD in carrying out Public Expenditures and community empowerment has not been carried out optimally. The obstacles faced in implementing the allocation are the lack of understanding of the Village Government apparatus regarding the main tasks and functions and the lack of information and socialization to the community. Quality of Human Resources (HR) That Has Not Supported the Management and Implementation of Village Fund Allocation. The culture of mutual cooperation among the people of Mudung Darat Village is starting to fade, and the culture of mutual cooperation is the hallmark of a village
Bioengineered Skin in Psoriasis Modeling: Investigation of Automated Injection Molding of Dermo-Epidermal Models as compared with Benchmark Manual Fabrication.
No full textBioengineered skin was initially developed for clinical application in reconstructive surgery, but nowadays it is also considered as a suitable skin model for research. Research applications range from assessment of cosmetic and pharmaceutical products to the modeling of pathological skin conditions. For example, psoriasis is a complicated skin disease that strongly concerns the scientific community because of its unclear pathogenesis and the current inability to cure it. The Pharmacogenomics Lab of ETH has been working on the development of psoriatic skin models in order to investigate the driving mechanisms of the disease and to later implement high-throughput drug screening to explore treatment possibilities. However, the manual production into transwell inserts results in unstable, self-contracting and inconsistent skin models, pain points that the Pharmacogenomics Lab would like to eliminate. A recent collaboration between the Product Development Group and the Pharmacogenomics Lab has been recently initiated in an attempt to standardize the fabrication of the psoriatic skin models. For this purpose, this Master Thesis focused on the investigation of the potentials and limitations of automated injection molding, a method developed by the Product Development Group, in the generation of consistent and representative dermo-epidermal models for psoriatic skin. After a series of experiments, it was seen that in-mold fabrication achieves homogeneous and consistent dermal hydrogels that maintain their dimensions throughout the whole cultivation period regardless of the collagen concentration employed for the dermal matrix, while automated injection molding allows the utilization of collagen concentrations higher than the unstable 5mg/ml, traditionally used in the manual fabrication method. All collagen concentrations exhibited similar biological performance, but the optimum fibroblasts viability was achieved in case of 5mg/mL, meaning that the whole injection molding process should be faster and even simpler to fully prevail over manual fabrication of skin models and better fit the requirements of skin disease research. Keratinocytes viability and differentiation was similar for all mold designs, all collagen concentrations and both fabrication methods. Development of a first psoriatic model, consisting of psoriatic fibroblasts and healthy keratinocytes, did not show any direct effect of diseased fibroblasts on keratinocytes proliferation and differentiation as the epidermal layer of the psoriatic model was very similar to this one of the healthy model.Evaluation of the automated seeding of keratinocytes for further standardization of the process and elongation of the psoriatic model’s cultivation period for a more thorough study should be the next steps. In the long-term, incorporation of all the psoriasis-related cells and molecules in a simple and fast way, as well as further advancements in the mold design to facilitate a direct high-throughput drug screening should be considered.Biomedical Engineering | Biomaterials and Tissue Biomechanic
Needs and contents of a customized digital tool for retention in care and medication adherence among pregnant and breastfeeding women living with HIV in Kilimanjaro
Get PDFThis research article was published by Bulletin of the National Research Centre Volume 47, 2023Background
Retention in care and adherence to medication among pregnant and breastfeeding women living
with HIV (PBWLH) are crucial for preventing mother‑to‑child transmission (PMTCT) of HIV. Wide coverage of mobile
phones, digital tools, including internet‑enabled medication dispensers and short message service (SMS), have
been recommended as potential interventions to improve adherence to medication by PBWLH. The main objective
of the study was to understand the needs and contents for a customized digital tool for retention in care and medica‑
tion adherence among PBWLH.
Method
A mixed‑methods study was conducted from September 2021 to March 2022 at five health facilities
in the Kilimanjaro region. We interviewed 142 pregnant and breastfeeding women, receiving PMTCT services, using
a semi‑structured questionnaire. Among the interviewed, twenty breastfeeding women were purposively selected
and enrolled to use an internet‑enabled Wisepill medication dispenser for one month. They received different types
of SMS reminders for one month, and feedback on their adherence patterns was received after one month using
an adherence graph from the Wisepill digital tool. Later, exit and in‑depth interviews were conducted to explore
the needs and contents of a future customized digital adherence tool. Descriptive analyses for quantitative data
and thematic content analyses for qualitative data were also done.
Results
Among 142 women interviewed, 42(30%) were pregnant and 100 (70%) were breastfeeding. Most 136 (95%)
had access to mobile phones and used SMS daily, while 90% were interested in receiving reminder messages. Qualita‑
tive findings revealed more insights into reminders’ content and educational SMS. Most people preferred neutral SMS,
which does not contain the word “medication”. Health educational SMS content was preferred to be on breastfeeding,
opportunistic diseases, nutrition and entrepreneurship education. Overall, SMSs were regarded as helpful to remind
clients of medication time and the medication dispenser provided them with privacy and safe storage for their
medication.
Conclusions
This study’s findings will help construct useful content for future digital adherence tools to support
the health of pregnant and breastfeeding women living with HIV
Buffalo Bill's diamond mine; or, The Bedouins of the plains / by the author of "Buffalo Bill."
No full textПостмодернистское направление в новогреческой литературе (на примере двух романов Маро Дука)
No full textВ статье рассматриваются постмодернистские черты двух романов Маро
Дука, проявляющиеся в системе персонажей, композиционной структуре, категории автора, временно – пространственных характеристиках.У статті розглядаються постмодерністські риси двох романів Маро Дука,
особлива увага приділяється системі образів, композиційній структурі, категорії
автора, часовим та просторовим характеристикам.In the article we point out the postmodern features in two novels by modern
Greek writer, Maro Duka, paying peculiar attention to the system of images, the plot
structure, the category of the author, the time and space characteristics
Постмодернистское направление в новогреческой литературе (на примере двух романов Маро Дука)
Get PDFВ статье рассматриваются постмодернистские черты двух романов Маро
Дука, проявляющиеся в системе персонажей, композиционной структуре, категории автора, временно – пространственных характеристиках.У статті розглядаються постмодерністські риси двох романів Маро Дука,
особлива увага приділяється системі образів, композиційній структурі, категорії
автора, часовим та просторовим характеристикам.In the article we point out the postmodern features in two novels by modern
Greek writer, Maro Duka, paying peculiar attention to the system of images, the plot
structure, the category of the author, the time and space characteristics
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