182,132 research outputs found

    Formal REA model at operational level

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    Despite a lot of attention gained by the Resource-Event-Agent (REA) framework among researchers in enterprise modeling, it still lacks comprehensive formal description. Most of the formalization approaches to REA use only UML or other graphical representation. This paper aims to define REA ontology at operational level using formal logic tools. The general approach to formal logic description of REA was motivated by LTAP introduced by Ito, Hagihara and Yonezaki. After basic REA concepts are presented, semantics and logical language LREA are defined including axioms for the REA operational level. Future research is shortly described in conclusion.REA framework; formal models; modal logic

    Enterprise modeling:process and REA value chain perspective

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    The paper focuses on enterprise business value chain modeling as an alternative to business process modeling. Well known REA methodology proposed by McCarthy and Geerts is used as the basic modeling framework. The research presented in the paper results in a generic semantic enterprise model using REA ontology. This rather static model is then converted into UML activity, sequence and state diagrams thus achieving dynamic view of the REA model. The dynamic REA view connects the process model and the value chain perspectives. It is shown that by using REA model transition called dynamization not only process models at task level can be achieved but also a consistency check of the REA model can be accomplished. By means of step by step value chain modeling of the enterprise a consistent process model can be reached preserving all advantages of the typical business process modeling methodsProcess model; Value chain model; REA; Production planning

    Rea, G C, WX6366

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    This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/412480Surname: REA. Given Name(s) or Initials: G C. Military Service Number or Last Known Location: WX6366. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 40559.229190 Item: [2016.0049.44742] "Rea, G C, WX6366

    Activation of an Estrogen/ Estrogen Receptor Signaling by BIG3 Through Its Inhibitory Effect on Nuclear Transport of PHB2/REA in Breast Cancer

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    Breast cancer is known to be a hormone-dependent disease, and estrogens through an interaction with estrogen receptor (ER) enhance the proliferative and metastatic activity of breast tumor cells. Here we show a critical role of transactivation of BIG3, brefeldin A-inhibited guanine nucleotide-exchange protein 3, in activation of the estrogen/ER signaling in breast cancer cells. Knocking-down of BIG3 expression with small-interfering RNA (siRNA) drastically suppressed the growth of breast cancer cells. Subsequent co-immunoprecipitation and immunoblotting assays revealed an interaction of BIG3 with prohibitin 2/repressor of estrogen receptor activity (PHB2/REA). When BIG3 was absent, stimulation of estradiol caused the translocation of PHB2/REA to the nucleus, enhanced the interaction of PHB2/REA and ER[alpha], and resulted in suppression of the ER[alpha]; transcriptional activity. On the other hand, when BIG3 was present, BIG3 trapped PHB2/REA in cytoplasm and inhibited its nuclear translocation, and caused enhancement of ER[alpha]; transcriptional activity. Our results imply that BIG3 overexpression is one of the important mechanisms causing the activation of the estrogen/ER[alpha]; signaling pathway in the hormone-related growth of breast cancer cells

    Homotopy types of Spin <sup>c</sup>(n) -gauge groups over S<sup>4</sup>

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    The gauge group of a principal G-bundle P over a space X is the group of G-equivariant homeomorphisms of P that cover the identity on X. We consider the gauge groups of bundles over S4 with Spin c(n) , the complex spin group, as structure group and show how the study of their homotopy types reduces to that of Spin (n) -gauge groups over S4 . We then advance on what is known by providing a partial classification for Spin (7) - and Spin (8) -gauge groups over S4 .</p

    [Receipt for the Transfer of Oswald's Clothing Via REA Express #2]

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    Receipts for the mailing of Lee Harvey Oswald's clothing via REA Express to the National Archives in Washington D. C

    sj-docx-1-rea-10.1177_17470161221131497 – Supplemental material for Overcoming barriers to informed consent in neurological research: Perspectives from a national survey

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    Supplemental material, sj-docx-1-rea-10.1177_17470161221131497 for Overcoming barriers to informed consent in neurological research: Perspectives from a national survey by Lauren R Sankary, Megan E Zelinsky, Paul J Ford, Eric C Blackstone and Robert J Fox in Research Ethics</p

    Selected works in analytic theology

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    Table of Contents: 1. The Hiddenness of God (2018, book published by Oxford University Press) 2. “Polytheism and Christian Belief” (2006, published in Journal of Theological Studies) 3. “The Metaphysics of Original Sin” (2007, published in Persons: Human and Divine, edited by Dean Zimmerman and Peter van Inwagen) 4. “Theology without Idolatry or Violence” (2015, published in Scottish Journal of Theology) 5. “Gender as a Divine Attribute” (2016, published in Religious Studies) 6. “Worship, Protest, and the Deformation of Prayer,” (2020, published in Essays in Analytic Theology, vol. 2, by Michael Rea

    Uma metodologia para análise e comparação do desempenho de empresas através de índices econômico-financeiros

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    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-graduação em Engenharia de Produçã
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