6,386 research outputs found
NMR based serum metabolomics analysis revealed similar serum metabolic alterations in Ischemic and Hemorrhagic Stroke patients
No full textBackground and Objective: Brain stroke (caused by interrupted blood supply to the brain) is one of the most common causes of disability and is the second highest cause of death in the world. Early diagnosis and treatment raises the chance of surviving a stroke, and can result in little or no disability. Treatment is based on the type of stroke and its primary cause; for ischaemic stroke (IS), medication or surgery or both can be recommended, whereas, for haemorrhagic stroke (HS, also known as intracerebral hemorrhage), surgery is recommended. However, there are scarcity of clinical markers which can differentiate IS from HS and further can provide information about severity of cerebral ischemia, endothelial injury, blood–brain barrier disruption, atherosclerosis, thrombus formation, inflammation, and oxidative stress. Metabolomics is a promising approach for identification of metabolic biomarkers and alterations associated with the diseased biology The present study is an effort to identify the diagnostic panel of serum metabolic profiles to differentiate between IS and HS patients and further could help predicting the severity of the cerebral ischemia. Methods: Blood serum samples were collected from suspected brain stroke patients at hospital admission within 6 hours after onset. The serum samples of patients clinically confirmed for IS and HS were only analysed using 800 MHz NMR spectroscopy. For comparative evaluation, the serum samples from 60 age and sex matched normal control (NC) subjects were also obtained for NMR analysis. The partial least square-discriminant analysis (PLS-DA) was performed to confirm the serum metabolic disparity between the study groups and metabolic features of discriminatory relevance were identified making composite use of mean decrease accuracy (MDA) score values estimated for metabolic features employing machine learning random forest (RF) classification analysis. The diagnostic potential of discriminatory metabolites were finally evaluated using receiver operating characteristic (ROC) curve analysis. Results: The serum metabolic profiles of total 107 brain stroke patients (48 IS and 60 HS) were measured and compared with those of 60 age and sex matched normal control (NC) subjects. Compared to NC, the serum levels of various amino acids (histidine, glutamine, threonine, alanine, glycine, dimethylglycine, pyruvate, etc.) were found to be decreased in both HS and IS patients, whereas those of creatine, mannitol, mannose, malonate and organic acids (such as acetate, 3-hydroxybutyrate and 3-hydroxy-isobutyrate) were found to be increased in the sera of brain stroke patients. However, the area under ROC (AUROC) curve values for majority of metabolic features found to be less than 0.8 for the discrimination between IS and HS suggesting that circulatory metabolic features lack sufficient sensitivity and specificity. Conclusions: The study provided primary evidence that various circulatory metabolites (including histidine, glutamine, and alanine) exhibited strong diagnostic potential for distinguishing brain stroke condition from NC subject, however, poor diagnostic accuracy in distinguishing IS from HS. Nevertheless, these metabolic changes can be used to assess the severity of brain stroke condition and monitoring patient response to treatment in emergency settings.The identified NMR based serum metabolic changes can be used to assess the disease severity and monitoring patient response to treatment in emergency settings
Bibliographics for the 983 eprints in the live archives of E-LIS : trends and status report up to 7th July 2004, based on author-self-archiving metadata
No full textThe priority for ideas and philosophy related to "Network Theory" have been traced back and documented by Braun(2004),and credit goes to Karinthy(1929).The IT has empowered to realise it, as the most practical phenomena and it is no more a humour. The OAI (Open Archives Initiatives)and ACIS (Academic Contributor Information System)are progressive in the direction ,which may lead to realise the "Collective Genius" at global level. Focus of present study is on Author-Self-Archiving (A-S-A)Metadata of the 983 Eprints in the Live Archives of the E-LIS (EPrints of Library and Information Science),which were approved till 7th July 2004.The A-S-A Metadata was used for librametric analysis. Self-explanatory bibliographics are illustrated.The highlights include: Conference papers (34%); highest approval, June 2004 (28%); published archives (76%);not refereed (52%); not in public domain (60%); highest self-archiving-author (De Robbio, Antonella).The Nos. of EPrints having single JITA domain specifications were: Theoretical and general aspects of libraries and information(27); Information use and sociology of information(80);Users,literacy and reading(13);Libraries as physical collections(30);Publishing and legal issues(57);Management(13);Industry, profession and education(36);Information sources, supports, channels(113) ; Information treatment for information services, Information functions and techniques (101); Technical services libraries, archives and museums(25); Housing technologies(1); Information technology and library technology(92); and Inter-domainery (395) i.e. having specifications of two or more than two JITA classes
A Unified Shell model for Buoyancy-Driven Turbulence
No full textWe construct a unified shell model for stably stratified and convective turbulence. Shell model simulation of stably stratified flow in turbulent regime exhibit Bolgiano-Obukhbov (BO) scaling in which the kinetic energy spectrum varies as . However, simulation of convective turbulence shows Kolmogorov's spectrum. These results are consistent with the direct numerical simulations of Kumar {\em et al.} [Phys. Rev. E {\bf 90}, 023016 (2014)]. We also observe a dual scaling ( and ) for a limited range of parameters in stably stratified flow
Residue Management and Nutrient Stoichiometry Control Greenhouse Gas and Global Warming Potential Responses in Alfisols
No full textAlthough crop residue returns are extensively practiced in agriculture, large uncertainties remain about greenhouse gas (GHG) emissions and global warming potential (GWP) responses to residue return (RR) rates under different residue placements and nutrient supplements. We conducted a laboratory mesocosm experiment in Alfisol in central India to investigate the responses of soil GHG emissions (CO2, N2O, and CH4) and the global warming potential to four wheat RR rates (R0: no residue; R5: 5 Mg/ha; R10: 10 Mg/ha; R15: 15 Mg/ha) and two placements (surface [Rsur] and incorporated [Rinc]) under three nutrient supplement levels (NSLs) (NS0: no nutrients, NS1: nutrients (N and P) added to balance the stoichiometry of C:N:P to achieve 30% humification in RR at 5 t/ha, NS2: 3 × NS1). The results demonstrated a significant (p R5 (3.8) > R15 (2.6) > R0 (1.6). Our results demonstrated a significant linear response of total GWP to RR rates R15 > R10 > R5 > R0, ranging from 201.4 to 1563.6 mg CO2 eq kg−1 soil. In conclusion, quadratic/linear responses of GHGs to RR rates underscore the need to optimize RR rates with nutrient supplements and residue placement to reduce GHG emissions and GWP while ensuring optimal soil health and crop productivity.This article is published as Singh, Dharmendra, Sangeeta Lenka, Narendra Kumar Lenka, Dinesh Kumar Yadav, Shashi S. Yadav, Rameshwar S. Kanwar, Abhijit Sarkar, and Jitendra Kushwaha. "Residue Management and Nutrient Stoichiometry Control Greenhouse Gas and Global Warming Potential Responses in Alfisols." Sustainability 16, no. 10 (2024): 3997. doi: https://doi.org/10.3390/su16103997
Story of the Story-Teller: A Conversation with Ramendra Kumar
No full textRamendra Kumar (Ramen) is an award-winning writer, storyteller and inspirational speaker with 42 books to his name. Ramen’s writings have been published by many of the leading publishers in the county and translated into 30 languages. They have found a place in several textbooks and anthologies. He has written across all genres ranging from picture books to adult fiction, satire, poetry, travelogues, biographies and on issues related to parenting and relationships. He has been invited to literary festivals held in Denmark, Greece, Sharjah, Sri Lanka as well Indian events including the prestigious Jaipur Litfest to conduct storytelling sessions and creative writing workshops. He has also been empanelled by Pearson India Education Services as well as several schools to conduct workshops. He was nominated as a Jury Member for the Best Children’s Author Category of The Times of India’s ‘Women AutHer’ Awards 2020. Many of his stories have been showcased by popular audio streaming, apps both within and outside the country, such as Spotify, Gaatha, Talking Stories Radio – London et al.
An Engineer & an MBA, Ramen was serving as the General Manager (Corporate Communications), SAIL, Rourkela Steel Plant, when he took Voluntary Retirement to pursue his passion, in August 2020. To know more about the writer, you can visit his website www.ramendra.in & his page on Wikipedia. Dr. Sagar Kumar Sharma interviews the author and unfolds the pages of his life.
 
Optimizing residue return with soil moisture and nutrient stoichiometry reduced greenhouse gas fluxes in Alfisols
No full textOptimum soil moisture and high crop residue return (RR) can increase the active pool of soil organic carbon and nitrogen, thus modulating the magnitude of greenhouse gas (GHG) fluxes. To determine the effect of soil moisture on the threshold level of RR for the wheat production system, we analyzed the relationship between GHG fluxes and RR at four levels, namely 0, 5, 10, and 15 Mg ha−1 (R0, R5, R10, and R15) under two soil moisture content (80% FC and 100% FC) and three levels of nutrient management (NS0: no nutrient; NS1, NS2= 3x NS1). Nutrient input (N and P) in NS1 balanced the residue C/nutrient stoichiometry to achieve 30% stabilization of the residue C input in RR (R5). All RR treatments (cf. R0) were found to significantly reduce N2O emission in moderate soil moisture content (80% FC) by 22–56% across nutrient management due to enhanced soil C mineralization, microbial biomass carbon, and N immobilization. However, averaged across nutrient management, a linear increase in N2O emission was observed with increasing RR under 100% FC soil moisture. A significant decrease in CH4 emission by ca. 46% in most RR treatments was observed in 100% FC compared with the R0. The N2O emission was negatively correlated (p= 0.8) to management variables (RR rate, nitrogen (N) input rate, soil moisture, and nutrient stoichiometry of C: N) and post-incubation soil properties (SMBC and NO3-N) in Alfisols. This study demonstrated that the mechanisms responsible for RR effects on soil N2O, CH4 fluxes, and carbon mineralization depend on soil moisture and nutrient management, shifting the nutrient stoichiometry of residue C: N: P.This article is published as Singh, Dharmendra, Sangeeta Lenka, Narendra Kumar Lenka, Dinesh Kumar Yadav, Shashi S. Yadav, Rameshwar S. Kanwar, Abhijit Sarkar, and Madhumonti Saha. "Optimizing residue return with soil moisture and nutrient stoichiometry reduced greenhouse gas fluxes in Alfisols." Frontiers in Sustainable Food Systems 8 (2024): 1490523. https://doi.org/10.3389/fsufs.2024.1490523
NOTICE!!! This person (known as Ashwin Kumar) plagiarized the text titled: "Using phenomenological research methods in qualitative health research"
No full textEDITORIAL NOTICE:
1. This publication has been removed due to detected plagiarism by the editorial.
2. If you have cited, you MUST UPDATE your reference with the following original article:
Wojnar, Danuta, and Kristen Swanson. “Phenomenology An Exploration”. Journal of holistic nursing : official journal of the American Holistic Nurses’ Association 25 (01 October 2007): 172-80; discussion 181. https://doi.org/10.1177/0898010106295172.
_________________________________________
3. Submitter's Profile Record (the thief, the plagiariser):
Name: Ashwin KumarURL: http://www.freewebs.com/ak2146Affiliation: University of Western Sydney, Australia.Country: AustraliaBio Statement:Dr. Ashwin Kumar,PO Box 571,Toongabbie,Sydney,Australia, NSW, 2146.Homepage: http://www.freewebs.com/ak2146Email: [email protected]
[email protected]: 0432-622-147Skype Internet Phone ID: ak2146
Dr. Ashwin Kumar (BA, MA (Distinction), PhD) is an academic researcher whose research interests and areas of expertise include: Complementary and alternative medicine (CAM), ageing and social gerontology, sociology, social anthropology, sociology of care, public health, health promotion, Indigenous health, migrant and refugee health, disability and chronic illness. Ashwin is the author of 8 books and numerous academic journal articles in the field of public health, health sociology and anthropology of health and illness. His books: The Lived Experience of Caring; The Lived Experience of Ageing; The Lived Experience of Using Complementary and Alternative Medicine; Doing Sociology; The Basics of Sociology; Plain English Writing; Research and Writing Skills and Writing Effective Essays are available at:
http://www.amazon.com/s/ref=ntt_athr_dp_sr_1?_encoding=UTF8&sort=relevancerank&search-alias=books&field-author=PhD.%20Ashwin%20Kumar
My homepage: http://www.freewebs.com/ak2146
________________________________________
Multivariate Quantitative Representativeness and Constituency Analysis of Ecological Observation Networks
No full textCite this code as: Kumar, J. (2023). Multivariate Quantitative Representativeness and Constituency Analysis of Ecological Observation Networks (Version 1.0) [Computer software]. https://doi.org/10.5281/zenodo.8048530
Multivariate Quantitative Representativeness and Constituency Analysis of Ecological Observation Networks
Author: Jitendra (Jitu) Kumar ([email protected]), Oak Ridge National Laboratory
Regional and global ecological research networks, representing coordinated and standardized as well as adhoc networks of observation sites, provide valuable observations necessary for ecological modeling and synthesis studies. Studies conducted across observational networks strive to scale up their results to larger areas, trying to reach conclusions that are valid throughout regional, continental, and even global scales. Network representativeness and constituency can show how well conditions at those locations represent conditions elsewhere within a larger area containing the network and can be used to help scale-up results over larger regions.
Representativeness: Euclidean distance between two sites plotted in multivariate environmental space can be used as an inverse measure of multivariate similarity to quantify representativeness. Close sites in environmental space have a similar combination of environmental factors, and therefore are highly representative of each other.
Constituency: For any site in the network, its Constituency represent all locations that are best represented by the multivariate environmental drivers at that site.
Code Compilation:
make
Edit the ```makefile``` as needed for your platform.
CC=gcc
CFLAGS= -O3
hpea: network_representativeness.o\
utility.o
(CFLAGS) *.o -lm -o network_representativeness
.o:
(CFLAGS) -c $<
clean:
\rm *.o network_representativeness
Running the representativeness analysis:
Usage: network_representativeness -infile input data file [ASCII]
-coordsfile coordinate file name
-clustfile coordinate file name [OPTIONAL -- must be used with -siteclustfile]
-sitefile site data file name
-siteclustfile site data file name [OPTIONAL -- must be used with -clustfile]
-nsites No. of sites
-minmaxfile minmax file name
-outfile output file name
-nrows No. of rows in input data
-ncols No. of variables
-details [OPTIONAL -- turn on output representativeness for each site, default is to write network representativeness and constituency only.]
-help program usage help.
Publications using ```network_reprentativeness``` code:
Kumar, J., Coffin, A. W., Baffaut, C., Ponce-Campos, G., Witthaus, L., and Hargrove, W. W. (2023) "Quantitative Representativeness and Constituency of the Long-Term Agroecosystem Research Network, and Analysis of Complementarity with Other Existing Ecological Networks", Environmental Management (in press)
M. M. T. A. Pallandt, J. Kumar, M. Mauritz, E. A. G. Schuur, A.-M. Virkkala, G. Celis, F. M. Hoffman, and M. Göckede. Representativeness assessment of the pan-arctic eddy covariance site network and optimized future enhancements. Biogeosciences, 19(3):559--583, 2022. https://doi.org/10.5194/bg-19-559-2022
J. Kumar, F. M. Hoffman, W. W. Hargrove, and N. Collier. Understanding the representativeness of FLUXNET for upscaling carbon flux from eddy covariance measurements. Earth System Science Data Discussion, 2016:1--25, August 2016. https://doi.org/10.5194/essd-2016-36.If you use this software, please cite it as below.
Kumar, J. (2023). Multivariate Quantitative Representativeness and Constituency Analysis of Ecological Observation Networks (Version 1.0) [Computer software]. https://doi.org/10.5281/zenodo.804853
Dilip Kumar: autor-aktor
No full textDilip Kumar has been praised for his sublime dialog delivery, for his restrained gestures, and for his measured and controlled underplay of emotions in tragic stories as well as in light-hearted comedies. His debut in 1944 with Jwar Bhata (Ebb and Tide) met with less-than-flattering reviews. So did the next three films until his 1948 film, Jugnu (Firefly), which brought him recognition and success. Unlike his contemporaries such as Raj Kapoor and Dev Anand, who propelled their careers by launching their own production companies, Dilip Kumar relied on his talent, his unique approach to characterization, and his immersion in the projects he undertook. In the course of his career that spanned six decades, Kumar made only 62 films. However, his work is a textbook for other actors that followed. Not only did he bring respectability to a profession that had been shunned by the upper classes in India as a profession for “pimps and prostitutes,” but he also elevated film-acting and filmmaking to an academic discipline, making him worthy of the title ‘Professor Emeritus of Acting’. Rooted in the theoretical framework of Howard S. Becker’s work on the “production of culture” and “doing things together,” this paper discusses Kumar’s approach to acting, character development, and the level of his involvement and commitment to each of his projects. The author of this article argues that more than the creative control as a producer or a director, it is the artistic involvement and commitment of the main actors that shape great works of art in cinema. Dilip Kumar demonstrated it repeatedly.Dilip Kumar był chwalony za wysublimowane prowadzenie dialogów, opanowaną gestykulację oraz za wyważone i kontrolowane wyrażanie emocji zarówno w opowieściach tragicznych, jak też w beztroskich komediach. Jego debiut w 1944 w Jwar Bhata (Odpływy i przypływy) spotkał się z niezbyt pochlebnymi recenzjami. Podobnie było z kolejnymi trzema filmami, aż do filmu Jugnu (Świetlik) z 1948 roku, który przyniósł mu uznanie i sukces. W przeciwieństwie do swoich rówieśników, jak Raj Kapoor iDev Anand, którzy napędzali kariery, uruchamiając własne firmy produkcyjne, Dilip Kumar polegał na swoim talencie, unikalnym podejściu do charakteryzacji i zaangażowaniu w projekty, których się podjął. W ciągu swojej sześćdziesięcioletniej kariery Kumar nakręcił tylko 62 filmy. Jednak jego praca jest podręcznikowa dla młodszych aktorów. Nie tylko przyniósł szacunek zawodowi aktora, traktowanemu przez indyjskie klasy wyższe jako zawód „alfonsów i prostytutek”, ale także podniósł aktorstwo filmowe i filmowanie do dyscypliny akademickiej, co uczyniło Kumara godnym tytułu emerytowanego profesora aktorstwa. Artykuł ten, zakorzeniony w ramach teoretycznych pracy Howarda S. Beckera nad „produkcją kultury” i „robieniem rzeczy razem”, omawia podejście Kumara do aktorstwa i rozwoju postaci oraz poziom jego zaangażowania w każdy ze swoich projektów. Autor tego artykułu przekonuje, że to artystyczne zaangażowanie i poświęcenie głównych aktorów kształtują wielkie dzieła sztuki w kinie bardziej niż kontrola twórcza producenta czy reżysera. Dilip Kumar wielokrotnie to zademonstrował
- …
