1,894 research outputs found
riboFrame: riboFrame
No full text<p>riboFrame: an improved method for microbial taxonomy profiling from non-targeted metagenomics Matteo Ramazzotti, Luisa Berná, Claudio Donati and Duccio Cavalieri</p>
<p>We present riboFrame, a novel procedure for microbial profiling based on the identification and classification of 16S rRNA sequences in non-targeted metagenomics datasets. Reads overlapping the 16S rRNA genes are identified and positioned onto a model 16S gene by HMMER using Hidden Markov Models or bacteria and archaea. A coverage plot can be created to evaluate whether we have a sufficient number of reads to continue to the following step. Next, a phylum-to-genus taxonomic assignment is given to all reads by naïve Bayesian classification using RDPclassifier. In the end, microbial abundance profiles can be created using all the reads available or just a subset from specific locations of the 16S genes (e.g. the popular V1-V3, V3-V5 or V6-V9 regions). We called this "post-hoc topological selection". In practice, we have transformed a non-targeted metagenomic experiments into a multi-targeted 16S microbial survey experiment.</p>
TUTELA DEL LAVORO E LIBERTA' D'IMPRESA NEI PROCESSI DI ESTERNALIZZAZIONE
No full textL’elaborato analizza le conseguenze lavoristiche della successione fra imprenditori, muovendo da una ricognizione delle varie tipologie di esternalizzazione con le relative esigenze e principali criticità.
L’indagine si concentra in primo luogo sul trasferimento d’azienda, esaminando la normativa e la giurisprudenza europee per passare poi alla disciplina di diritto interno, alle procedure sindacali e a uno specifico focus sul trasferimento delle aziende in crisi.
Successivamente l’autore si sofferma sull’appalto, prendendone in particolare considerazione gli indici di genuinità, i criteri di distinzione dalla somministrazione illecita di manodopera e la tutela delle maestranze in caso di avvicendamento fra imprese.
Da ultimo, la ricerca approfondisce le c.d. “clausole sociali”, sia di prima che di seconda generazione, valutandone la compatibilità con il diritto eurounitario e con la costituzione nonché riflettendo sui possibili rimedi in caso di loro violazione.The author analyzes the labour consequences of the succession between entrepreneurs, starting from a recognition of the various types of outsourcing with the related needs and main critical issues.
The survey focuses primarily on the transfer of businesses, examining European legislation and case-law and then moving on to internal legislation, trade union procedures and a specific focus on the transfer of companies in crisis.
The author then dwells on the contract, taking into account in particular the indications of authenticity, the criteria of distinction from the illicit administration of labour and the protection of workers in the event of turnover between companies.
Finally, the research deepens the "social clauses", both first and second generation, assessing their compatibility with European law and with the constitution and reflecting on possible remedies in case of their violation
Internal Migration, Local Development and Structural Change: Evidence from the Italian Golden Age
No full textInternal migration facilitates an efficient allocation of labor within the economy, but are its sending and receiving areas affected differently? We address this question through the lens of Italy during the Golden Age (1950s-1970s), a period of population reshuffling with no parallel in the country’s history. Exploiting detailed spatial data on migratory flows, we characterize the impact of short- and long-distance migration on economic development and structural change in the provinces of origin and destination. To tackle endogeneity of migration flows, we build on recent advances in the shift-share IVs literature: we interact past interwar governmentauthorized migrations with employment growth during the Golden Age to estimate exogenous short-distance migrations; origin-destination railway distances with provinces’ employment growth for long-distance ones. We find that short-distance emigration negatively affected origin provinces’ value added per capita mostly through lower business creation and productivity, while it determined even larger productivity gains in destination provinces. Similarly, shortdistance immigration boosted structural change away from agriculture in favor of the industrial sector, while emigration curbed it in the provinces of origin, by reducing employment, value added and productivity in industry. We do not find comparably strong results for long-distance flows, which are shown to negatively affect origin provinces mostly through the employment rate, while the effects on productivity are limited; receiving provinces are also not as affected. We attribute the difference between short and long-distance effects to selection by type of migrants, where the most productive ones tend to favor nearby destinations
Ultra Low Carbon Vehicles: New Parameters for Automotive Design
No full textAs the influence of vehicle emissions on our environment has become better understood, the UK government has recently placed urgent emphasis on the implementation of low carbon
technologies in the automotive industry through: the UK Low Carbon Industrial Strategy. The overall objective is to offer big incentives to consumers and support for the development of infrastructure and engineering solutions. This scheme however does not consider how the development of functional and experiential user value might drive consumer demand, contributing to the adoption of low carbon vehicles (LCVs) in the mass market.
With the emergence of the North East of England as the UK’s first specialised region for the development of ultra-low carbon vehicles (ULCVs), ONE North East, as a development agency for the region's economic and business development, and Northumbria University Ideas-lab have supported a project to facilitate innovation through the collaboration of technology, research and development (R&D) and business. The High Value Low Carbon (HVLC) project aims to envisage
new user value made possible by the integration of low carbon vehicle platforms with new process and network technologies. The HVLC consortium represents vehicle manufacturers and their suppliers as well as technology based companies and through an ongoing process of design concept generation the project offers a hub for innovation led enterprise.
Whilst new technological developments in areas such as power generation, nano materials, hydrogen fuel cells, printed electronics and networked communications will all impact on future automotive design, the mass adoption of low carbon technologies represents a paradigm shift for the motorist. This paper aims to describe how the mapping of new parameters will lead to new transport scenarios that will create the space for new collaborative research on user experiences supported by innovative technologies and related services
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Matteo Maria Boiardo (1441-1494)
No full textMatteo Maria Boiardo – contemporary of Sir Thomas Malory and forerunner of Shakespeare, Spenser, Milton, Cervantes, Tolkien, and C.S. Lewis – is best known as the author of the Orlando Innamorato [Orlando in Love], a poem in ottava rima organically merging Carolingian epic and Arthurian romance. He was also a lyric and pastoral poet, playwright, and translator of classical texts into the Italian vernacular. Matteo was active in Italy during the years of 1463 throughout 1494, the year of his death
Uno sguardo all'Est. Lavoro e diritti fondamentali in Russia e negli altri Paesi della Comunità di Stati indipendenti
No full textNel contributo l'autore, dopo aver esaminato i diritti fondamentali del lavoro presenti nelle Costituzioni dei Paesi della Comunità di Stati indipendenti, si sofferma sul diritto del lavoro russo. La trattazione, a carattere diacronico, abbraccia i rami principali del diritto del lavoro: il rapporto individuale, le relazioni collettive, il mercato del lavoro. L'autore rileva una sorprendente continuità nelle linee essenziali del diritto del lavoro russo, pur nel susseguirsi di sistemi socioeconomici completamente diversi. Egli conclude che il diritto del lavoro russo appartiene saldamente alla matrice europea della materia.The contribution of the author starts by examining fundamental labour rights recognised by the Constitutions of the Countries of the Community of Independent States. Then the author focuses upon Russian Labour Law, going through the history of the main branches of the discipline: the individual relationship, industrial relations, the labour market. The article finds a surprising continuity in the essential lines of Russian Labour Law, in spite of the completely different socio-economic systems that were experimented in Russia during the twentieth century. The author concludes that Russian Labour Law clearly belongs to the European matrix of the discipline
Corpo, spazio, architettura. Fenomenologia dell’esperienza spaziale Matteo Vegetti, Fabrizia Bandi (eds.), Editrice Morcelliana, Brescia 2024
No full textThe author reviews "Corpo, spazio, architettura: Fenomenologia dell’esperienza spaziale," edited by Matteo Vegetti and Fabrizia Bandi. The book examines the philosophical underpinnings of spatial experience through a phenomenological lens, engaging with both traditional and contemporary notions of how space, body, and architecture interconnect. The author highlights the text\u27s exploration of how architects and designers might integrate phenomenological insights into their work, transforming space from mere physical dimensions into lived, experienced reality. The review appreciates the book’s thematic organization, which starts with foundational theories from Merleau-Ponty and expands through discussions on virtual spaces and the future of architecture in the digital age. Through this anthology, readers gain a comprehensive view of the architectural implications of phenomenological thought, making it a critical resource for anyone involved in the conceptualization and design of space
recluster: an unbiased clustering procedure for beta‐diversity turnover
No full textWhen dissimilarity matrices of faunistic and phylogenetic beta-diversity
turnover indices are projected in dendrograms, a high frequency of ties
and zero values produces trees whose topology and bootstrap support are
affected by the order of areas in the original presence-absence matrix.
We tested the magnitude of this bias and developed R functions to obtain
consensus trees after shuffling of matrix row order and applied this
algorithm to a multiscale bootstrap procedure. Our functions not only
solve the bias of row order but, owing to varying support for different
bootstrap scales, reveal fundamental characteristics about the structure
of species assemblages
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