14 research outputs found
Acculturation Chinese Symbol on Madura Batik Motif
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Home > Vol 12, No 4 (2016) > Karsono
Acculturation Chinese Symbol on Madura Batik Motif
Ong Mia Farao Karsono, Lintu Tulistyantoro
Abstract
This study has two chief purposes. Firstly, to introduce the Madurese Batik from Indonesia which has not yet been widely studied, and secondly, to show the acculturation of the Chinese culture in the motif of Madurese Batik. Research method employed in this study was descriptive qualitative, because our topic involves cultural and humanity sciences. The writers interview batik makers from the towns of Pamekasan, Tanjung Bumi, Sumenep, and Sampang, as research informants. We take two batik makers as representatives of each town. The four towns are selected because those towns are the centers of batik in Madura. To crosscheck the information obtained from the batik makers, also interview two collectors of Madurese batik who have good knowledge of Madurese batik. The data from the interviews and the photographic documentation of Madurese batiks are sorted and then analyzed by relating them to the theories about Madurese culture, acculturation process, and Chinese culture. The discussions and conclusions of the analyses correspond with the hypotheses proposed at the beginning of the study, which states that there are acculturations of the symbols on Madurese Batik motifs, which can be seen in the paintings of phoenix, butterfly, fish, bamboo trees on the batik, and that the acculturation process occurs naturally without conscious knowledge of the Madurese
E-cadherin and Vimentin as Predictors of Resistance to Preoperative Systemic Therapy in Patients with Advanced Breast Cancer
No full textE-cadherin and Vimentin as Predictors of Resistance to Preoperative Systemic Therapy in Patients with Advanced Breast Cancer
No full textLoss of E-cadherin and increased vimentin expression are associated with epithelial-mesenchymal transition andcancer stemness which are responsible for treatment resistance. The study aims to evaluate the role of E-cadherin andvimentin as predictors of resistance to preoperative systemic therapy in patients with advanced breast cancer. This wasa cross-sectional analytical study in patients with stage III-IV breast cancer in Dharmais Cancer Hospital and dr. CiptoMangunkusumo National Hospital from July 2015 to April 2016. Patients had biopsy specimens embedded in paraffinblocks. Expressions of E-cadherin and vimentin proteins were done immunohistochemically. Treatment response wasevaluated histopathologically using Miller-Payne criteria on mastectomy specimens. A total of 65 patients were enrolled.Five patients with invasive lobular carcinoma were excluded. Thirty one had chemotherapy and 29 had hormonaltherapy. After treatment, 46 patients were eligible for mastectomy. E-cadherin and vimentin were positive in 28 (60.9%)and 11 (20.3%) of specimens. Twenty-three (50%) patients showed no response. Treatment resistance were associatedwith type of therapy (OR=4.4; 95% CI=1.27-15.41; p=0.017) and vimentin expression (OR=6.75; 95% CI=1.27-30.02;p=0.016). Hormonal therapy (ORadj=6.26; 95%CI=1.59-24.6; p=0.009) and positive vimentin (ORadj=8.75; 95%CI=1.43-57.4; p=0.019) were independent predictors of treatment resistance. In conclusion, E-cadherin and vimentin can beused as predictors of resistance to preoperative systemic therapy in patients with advanced breast cancer
Jurnal Nasional Terakreditasi SINTA 4 dengan Judul "Kebijakan Telemudik Bentuk Perlindungan Negara Pada Masyarakat Menuju New Normal Ditengah Pendemi Corona"
Get PDFJumlah masyarakat yang meninggal dunia akibat covid-19 juga terus meningkat begitu pula dengan jumlah masyarakat yang terinfeksi virus corona (Covid-19). Sampai dengan bulan Mei 2021 bertepatan menjelang hari raya Idul Fitri 1442 H, yang secara adat kebiasaan masyarakat Jakarta, melakukan mudik untuk bersilahturahmi dengan keluarga di daerah. Pada saat itu, Jakarta masih dalam zona merah karena lonjakan sebaran kasus Covid-19. Negara dalam hal ini Pemerintah harus hadir melindungi masyarakatnya baik yang terinfeksi covid-19 maupun agar tidak terinfeksi Covid-19. Perlindungan tersebut berupa diterbitkannya Regulasi berupa Surat Edaran Satuan Tugas Penanganan Covid-19 nomor 13 tahun 2021 tentang Peniadaan Mudik Hari raya idul fitri tahun 1442 Hijriah dan upaya pengendalian penyebaran covid-19 selama bulan suci Ramadhan 1442 Hijriah untuk mengubah perilaku ignorance masyarakat terhadap pandemic Covid-19. Penelitian ini menggunakan pendekatan kualitatif dengan mengutamakan data sekunder, untuk mengetahui apa latar belakang terbitnya kebijakan telemudik tersebut. Kesimpulan yang ditarik dari penelitian kepustakaan ini bahwa yang melatarbelakangi lahirnya kebijakan telemudik adalah perilaku ignorance masyarakat terhadap pandemic covid itu sendiri Solusi yang tepat untuk melaksanakan mudik pada masa Pandemi Covid-19 adalah dengan telemudik untuk tidak mengurangi esensi bersilahturahmi dan berbagi dan mempersiapkan masyarakat menuju New Normal ditengah Pendemi Corona
Dialogic Elements of Bakhtin in the Novel Siddhartha
Get PDFThis article analyzes the voices of the characters which are intertwining into dialogic forms. The voices did not demonstrate its own power, but rather let other voices have its own characteristic while remaining there
until the end of the story. For example, Siddharthas parents voices remained a Brahmin . Govinda’s voice remained a Samana . Mikhail Bakhtin called such characteristic dialogue as Internally Persuasive Discourse
.
Apparently this novel is loaded full of Bakhtins carnival behavior, because the composition and the plot of the story, or the position of the author as well as the dialogue, a hallmark of Socratic Dialogue or Menippean Satire
.
Unveiling Bakhtin’s carnival stage, a variety of scandals, eccentric behaviors, ethic violations, sharp contrasts appear. The polyphony nature in this novel is in the form of counterpoint models voices intertwined together without negating each other, similar to the Weltemperklavier by Johan Sebastian Bach in the Baroque music era
CREATING THE OPEN SPACE’S SENSE OF PLACE Case Study: Deli’s Sultanate Area
Get PDFCreating the open space that possesses sense of place is a creative process which involves user, designer and open space’s management. The open space should be able to accommodate the daily activities, experiences and possess diversity. The open space should be context with the environment, give a special sense and safe for people.
In this paper, ‘creating sense of place’ means to establish and create a ‘place’ which possesses special sense belonging to the site (example: history, culture, tradition, aesthetic value, social, economy, function, climate and physical). It is also important to analyze the sense of the past, the interest of present day and its relation to the future.
The purpose of this paper is to improve and enhance the image of Deli’s Sultanate area which has three significant objects, such as: Maimun Palace, Al Mashun Grand Mosque, and Sri Deli Park. To generate new open space elements and space order that could be a special ‘place’ for the user, author has carried out the identification, analysis, and re-arrangement study of the open space in the site of case study area.
Keyword: open space, sense of place, public space, place, Deli’s Sultanate area
Creating the Open Space’s Sense of Place Case Study: Deli’s Sultanate Area
Get PDFCreating the open space that possesses sense of place is a creative process which involves user, designer and open space’s management. The open space should be able to accommodate the daily activities, experiences and possess diversity. The open space should be context with the environment, give a special sense and safe for people.
In this paper, ‘creating sense of place’ means to establish and create a ‘place’ which possesses special sense belonging to the site (example: history, culture, tradition, aesthetic value, social, economy, function, climate and physical). It is also important to analyze the sense of the past, the interest of present day and its relation to the future.
The purpose of this paper is to improve and enhance the image of Deli’s Sultanate area which has three significant objects, such as: Maimun Palace, Al Mashun Grand Mosque, and Sri Deli Park. To generate new open space elements and space order that could be a special ‘place’ for the user, author has carried out the identification, analysis, and re-arrangement study of the open space in the site of case study area.
Keyword: open space, sense of place, public space, place, Deli’s Sultanate area
KETIDAKADILAN GENDER PADA TOKOH PEREMPUAN DALAM NOVEL WANITA DI JANTUNG JAKARTA KARYA KORRIE LAYUN RAMPAN
Get PDFABSTRAKPenelitian ini bertujuan untuk mendeskripsikan fakta cerita, serta ketidakadilan gender pada tokoh perempuan bernama Sumarsih dalam novel Wanita di Jantung Jakarta karya Korrie Layun Rampan. Penelitian ini menggunakan metode pustaka kualitatif dengan pendekatan deskriptif, yaitu untuk memperoleh informasi dan gambaran tokoh perempuan dalam novel Wanita di Jantung Jakarta berdasarkan ketidakadilan gender pada tokoh perempuan. Penelitian ini menggunakan pendekatan struktural. Dalam penelitian ini penulis menggunakan teknik baca, teknik catat, dan teknik pustaka. Teknik analisis data yang digunakan dalam penelitian ini adalah analisis data kualitatif meliputi reduksi data, penyajian data, dan penarikan simpulan. Hasil penelitian adalah sebagai berikut. Pertama, fakta cerita dalam novel Wanita di Jantung Jakarta karya Korrie Layun Rampan terdiri atas alur, tokoh dan penokohan dan latar. Alur yang terdapat dalam novel ini adalah alur campuran. Tokoh dan penokohan dalam cerita ini mempunyai peranan sebagai tokoh utama yaitu Sumarsih dan tokoh tambahan yaitu Sumarto, Tantono, Karsono, Suwarto dan Pitak Sastra, dengan penokohan yaitu tokoh protagonis Sumarsih dan Sumarto, dan tokoh antagonis Tantono, Karsono, Suwarto dan Pitak Sastra. Latar dalam cerita ini berada di Jakarta. Kedua, ketidakadilan genderpada tokoh perempuan Sumarsih yaitu Streotipe (Pelabelan Negatif) Sumarsih dianggap peselingkuh dan Sumarsih ingin di jual oleh suaminya sendiri karena Sumarsih cantik, Marjinalisasi (Peminggiran) Sumarsih dianggap kurang wawasan dan pengalaman karena itu gampang untuk ditipu, Subordinasi (Penomorduaan) Sumarsih dipaksa menikah dan harus meninggalkan bangku kuliahnya, Kekerasan (Violence) Sumarsih mengalami kekerasan fisik dan juga non fisik, dan Beban Ganda, Sumarsih pencari nafkah atas hidupnya sendiri setelah bercerai dan diceraikan. ABSTRACTThis research aims to describe story facts, and gender injustice to a female character named Sumarsih in a novel Wanita di Jantung Jakarta by Korrie Layun Rampan. This research using the qualitative library method with a descriptive approach, that is to obtain information and the description of female figures in a novel Wanita di Jantung Jakarta based on gender injustice in a female leaders. This research using structural approach. In this research the author uses reading technique, note technique, and library technique. Data analysis techniques used in this study is the analysis of qualitative data including reduction of data, presentation of data and conclusions. The results of the study are as follows. First. Story facts in novel Wanita di Jantung Jakarta by Korrie Layun Rampan consists of plot, character and characterization and background. The flow found in this novel is a mixed groove. Character and characterization in this novel has a role as the main character namely Sumarsih and additional figures namely Sumarto, Tantono, Karsono, Suwarto, and Pitak Sastra, by characterizing the protagonist Sumarsih and Sumarto, and antagonist character Tantono, Karsono, Suwarto and Pitak Sastra. The background in this story is in Jakarta. Second. gender injustice to Sumarsih female leaders that is Stereotype (negative labeling), Sumarsih considered an cheater and Sumarsih she wanted to sell by her husband because she was beautiful, Marginalization, Sumarsih considered insufficient insight and experience because it was easy to cheat, Subordination (nomination), Sumarsih was forced to get married and have to leave college, Violence, Sumarsih experienced physical and non-physical violence, and Double burden, Sumarsih breadwinner for his own life after divorced
Role of Estrogen Receptor Alpha rs3798577 Polymorphism in Breast Carcinoma Risk Determination
No full textBACKGROUND: Interaction between estrogen and estrogen receptor (ER) takes part in the regulation and differentiation of breast tumorigenesis. Some ERα polymorphisms, including ERα rs3798577, are reported to be associated with the risk and aggressiveness of breast carcinoma since the site was reported to be targeted by microRNA, which can further modulate the ERα expression. Hence, this study was conducted to disclose the possible role of ERα SNP rs3798577 on breast carcinoma patients.
METHODS: Samples were taken from the post-mastectomy breast carcinoma tissues of female patients and screened based on the completeness of medical and histopathological records. DNA isolation was proceeded using real time-polymerase chain reaction (RT-PCR) then analyzed for high resolution melting (HRM). The nucleotide base sequence was then analyzed based on rs3798577 ERα polymorphism. ER immunohistochemistry test was carried out and counted quantitatively based on the staining intensity and the percentage of the stained cells.
RESULTS: Out of 65 samples, there were 33 samples as wild type and 32 samples as variant type. Most variant and wild type had >80% ERα percentage. Most variant type had middle ERα intensity, while wild type had strong ERα intensity. Higher percentage of variant type (52.2%) was found with weak ERα histoscore, meanwhile higher percentage of wild type (52.4%) was found with strong ERα histoscore, but not significant (p=0.725).
CONCLUSION: ERα rs3798577 variant type had a lower ERα intensity and weaker ERα histoscore compared to the wild type, suggesting that ERα rs3798577 polymorphism might play a role in breast carcinoma risk determination
Hubungan Ekspresi MiR-21 dan MiR-200c dengan Respons Terapi Sistemik Neoajuvan Pasien Kanker Payudara Stadium Lanjut
No full textKegagalan terapi pada kanker payudara stadium lanjut dihubungkan dengan ekspresi mikroRNA antara lain miR-21 dan miR-200c. Untuk mengetahui hubungan respons terapi sistemik neoajuvan serta ekspresi miR-21 dan miR-200c pada pasien kanker payudara, dilakukan studi potong lintang di RS Kanker Dharmais dan RSUPN dr. Cipto Mangunkusumo (RSUPNCM) pada bulan Juli 2015 hingga April 2016. Subjek yang memiliki spesimen jaringan segar dan blok parafin serta telah mendapat pengobatan adekuat, dilakukan pengukuran MiR-21 dan miR-200c dengan qRT-PCR. Hasil dinyatakan sebagai perbedaan cycle thresholds (ΔCt) terhadap U6 snRNA. Ekspresi relatif dihitung sebagai perbedaan dua nilai ΔCt (ΔΔCt) dan fold change (2-ΔΔCt). Sebanyak 31 dari 60 subjek mendapat kemoterapi dan 29 mendapat terapi hormonal. Setelah terapi neoajuvan, hanya 46 orang subjek yang dapat menjalani mastektomi. Respons terapi dinilai dengan kriteria Miller Payne dari sediaan operasi. Sebanyak 23 (50%) subjek tidak respons (Miller Payne grade 1). ΔCt miR21 dan ΔCt miR-200c tidak berbeda bermakna pada subjek yang responsif dan tidak responsif, namun subjek yang tidak responsif memperlihatkan peningkatan ekspresi miR-200c (FC=2,375). Berdasarkan jenis terapi neoajuvan ekspresi miR21 maupun miR-200c lebih tinggi pada kelompok tidak respons dengan kemoterapi, sedang pada pemberian hormonal ekspresi miR-21 lebih rendah dan miR-200c cenderung lebih tinggi. Disimpulkan ekspresi miR-21 dan miR-200c tidak dapat digunakan untuk memprediksi respons terapi. Association of Expression of miR-21, miR-200c and response of Neoadjuvan Systemic Therapy in Patients with Breast Cancer Treatment failure in advanced stage breast cancer has been associated with expression of microRNA e.g. miR-21 and miR-200c. To know the association between response neoadjuvant systemic therapy and the expressions of miR-21 and miR-200c in breast cancer patient, a cross-sectional study has been conducted in Dharmais Cancer Hospital and dr. Cipto Mangunkusumo Hospital National (CMHN) from July 2015 to April 2016. Patients had fresh and paraffin-embedded tissues from biopsy specimens and have been treated adequately. MiR-21 and miR-200c were measured using qRT-PCR on fresh tissues. Results were expressed as cycle thresholds difference (ΔCt) against U6 snRNA. Relative expression was calculated as difference of two ΔCt values (ΔΔCt) and fold change (2-ΔΔCt). Treatment response was evaluated histopathologically using Miller-Payne criteria on mastectomy specimens. A total of 60 patients were enrolled, 31 had chemotherapy and 29 had hormonal therapy. After treatment, only 46 patients were eligible for mastectomy. Twenty-three (50%) patients showed no response (Miller-Payne grade 1) after treatment. ΔCt miR-21 and ΔCt miR-200c were not significantly different between responsive and not responsive patients. However, patients with no response showed increased expression of miR-200c (FC=2.375). Based on type of neoadjuvant , in chemotherapy group expression of miR-21 and miR-200c were high(FC=3.67 and 6.16 respectively) but in hormonal group expression miR-21 FC=0.11 and miR-200c FC=1.25). In conclusion, expressions of miR-21 and miR-200c cannot be used to predict treatment response
