171,518 research outputs found

    A Poetic Record of the Rajput Rebellion, c. 1680

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    AbstractThrough comparison of three poetic texts describing the career of Rana Raj Singh of Mewar (r. 1652–1680), this paper demonstrates how representations of Aurangzeb could vary dramatically even when they were produced for the same Rajput court. Much of the paper focuses on Rāj-vilās, a vernacular-language work with a lengthy account of conflict between Aurangzeb and the Rajput lords of Marwar and Mewar. Rāj-vilās is also noteworthy for its negative portrayal of the Mughal emperor, whom it castigates as a wicked killer of kin who was duplicitous and vengeful. Sometimes thought to be modern constructions, the criticisms of Aurangzeb found in Rāj-vilās reveal that certain ideas about Indian historical figures have continued to be deployed and repurposed over the centuries. Yet Rajput views during Aurangzeb's lifetime were not uniformly unfavourable, as the Sanskrit texts Rāja-ratnākara and Rāja-praśasti attest. Although these two works resembled Rāj-vilās in covering the reign of Rana Raj Singh and were written at roughly the same time, they cast Aurangzeb in a considerably more positive light. This difference can be attributed to the fluctuating political relationship between the Mughal empire and the Mewar kingdom in the decade between 1677 and 1687, underscoring the need to carefully identify the historical contexts within which representations of Aurangzeb were produced and circulated.</jats:p

    Orthographic influences, vocabulary development and phonological awareness in deaf children who use cochlear implants

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    In the current study, we explore the influence of orthographic knowledge on phonological awareness in children with cochlear implants and compare developmental associations to those found for hearing children matched for word reading level or chronological age. We show an influence of orthographic knowledge on syllable and phoneme awareness in deaf and hearing children, but no orthographic effect on rhyme awareness. Nonorthographic rhyme awareness was a significant predictor of reading outcomes for all groups. However, whereas receptive vocabulary knowledge was the most important predictor of word reading variance in the cochlear implant group, rhyme awareness was the only important predictor of word reading variance in the reading level matched hearing group. Both vocabulary and rhyme awareness were equally important in predicting reading in the chronological age-matched hearing group. The data suggest that both deaf and hearing children are influenced by orthography when making phonological judgments, and that phonological awareness and vocabulary are both important for reading developmen

    Genetic variation at the apolipoprotein B gene and associations with coronary heart disease and its factors.

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    PhDCoronary heart disease (CED) is the major cause of mortality in Western societies. The main risk factors are plasma lipoprotein concentrations, smoking, blood pressure and family history. The effect of family history implies a genetic contribution to the aetiology, support for which has also come from twin, and other heritability studies. The genetic component of CHID may be studied by the candidate gene approach, whereby the genes of products most likely to be involved in the processes leading to CHD, and in its risk factors, are analysed. The plasma concentration of apolipoprotein (apo) B, the major protein component of low density lipoprotein (LDL), is positively correlated with the risk of developing CHD. In this research, the gene for apo B was analysed for restriction enzyme fragment length polymorphisms (RFLPs). A RFLP is caused by a sequence change in the DNA, and results in length variation in the fragments. RFLPs for apo B have been shown to be associated with CHD and the plasma concentrations of cholesterol, triglycerides and apo B in some population studies. However, other studies have failed to confirm these relations. The work described in this thesis was designed to overcome some of the problems which niay have produced these inconsistencies. A random sample of 300 men, aged 49-65 years, residing in South Wales was studied. RFLPs determined in these individuals were used to generate genotypes and haplotypes (arrangements of specific alleles on a single chromosome). Significant associations were found between some genotypes and some haplotypes with altered concentrations of plasma total cholesterol and LDL cholesterol and with risk of CHD and/or with obesity. Presence of Xbal site (X2X2 genotype) was significantly associated with higher concentrations of plasma LDL cholesterol (p=0.0 19). Absence of Mspl site (M 1) was associated with significantly elevated concentrations of plasma total and LDL cholesterol (p < 0.05) by both the techniques of genotype and haplotype analysis. EcoRl RFLP (absence of the site - El) was the minimum haplotype necessary to detect a significant association with decreased plasma cholesterol J Rajput- Williams Ph. D. Thesis Page 3 concentrations (p < 0.05). Genotypes generated from alleles defined by the Mspl-EcoRl RFLPs were associated with significant variation in serum cholesterol concentration (p < 0.03), showing a stratification of concentration with the highest being associated with loss of the Mspl site and the lowest with the presence of the EcoRl site. Both these RFLPs result in charged aminoacid alterations, and lie close to the LDL receptor binding domain of apo B. The minimum haplotype necessary for detection of apo B with CHD was Xbal-Mspl (p < 0.05). The minimum haplotype associated with obesity was the RFLP pair Pvull-Xbal (p < 0.05). Further examination for mutations of the CpG dinucleotide which may influence cholesterol metabolism was undertaken by screening around the putative LDL receptorbinding domain (RBD) of the apo B gene. One variant was detected for aminoacid residue 3500 (Arg,,,,, 4 Gln) mutation, and two variants for aminoacid residue 3611 which also corresponds to the MspI mutation (Arg,,, ,4 Gln)

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Mitomycin C in highly myopic eyes - Author reply

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    Ophthalmology. 2005 Feb;112(2):208-18; discussion 219. Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes. Gambato C, Ghirlando A, Moretto E, Busato F, Midena E. SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy. Abstract PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes. DESIGN: Prospective, double-masked, randomized clinical trial. PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia. METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months). MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH. RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively). CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK. Comment in Ophthalmology. 2006 Feb;113(2):357; author reply 357-8

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Kingship and Polity on the Himalayan Borderland: Rajput Identity during the Early Colonial Encounter

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    This book explores the modern transformation of state and society in the Indian Himalaya. Centred on three Rajput-led kingdoms during the transition to British rule (c. 1790-1840) and their interconnected histories, it demonstrates how border making practices engendered a modern reading of 'tradition' that informs communal identities to date. By revising the history of these mountain kings on the basis of extensive archival, textual, and ethnographic research, it offers an alternative to popular and scholarly discourses that grew with the rise of colonial knowledge. This revision ultimately points to the important contribution of borderland spaces to the fabrication of group identities

    Kingship and Polity on the Himalayan Borderland: Rajput Identity during the Early Colonial Encounter

    No full text
    This book explores the modern transformation of state and society in the Indian Himalaya. Centred on three Rajput-led kingdoms during the transition to British rule (c. 1790-1840) and their interconnected histories, it demonstrates how border making practices engendered a modern reading of 'tradition' that informs communal identities to date. By revising the history of these mountain kings on the basis of extensive archival, textual, and ethnographic research, it offers an alternative to popular and scholarly discourses that grew with the rise of colonial knowledge. This revision ultimately points to the important contribution of borderland spaces to the fabrication of group identities

    Permutations of Rajput identity in the West Himalayas, c. 1790-1840

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    The sustained interaction of local elites and British administrators in the West Himalayas over the decades that surrounded the early colonial encounter (c. 1790-1840) saw the emergence of a distinctly new understanding of communal identity among the leaders of the region. This eventful period saw the mountain ('Pahari') kingdoms transform from fragmented, autonomous polities on the fringes of the Indian subcontinent to subjects of indigenous (Nepali, Sikh) and, ultimately, foreign (British) empires, and dramatically altered the ways Pahari leaders chose to remember and represent themselves. Using a wide array of sources from different locales in the hills (e.g., oral epics, archival records and local histories), this thesis traces the Pahari elite's transition from a nebulous group of lineage-based leaders to a cohesive unitary milieu modelled after contemporary interpretations of Hindu kingship. This nascent ideal of kingship is shown to have fed into concurrent understandings of Rajput society in the West Himalayas and ultimately to have sustained the alliance between indigenous rulers and British administrators.EThOS - Electronic Theses Online ServiceGBUnited Kingdo
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