197,732 research outputs found
ATR restrains DNA synthesis and mitotic catastrophe in response to CDC7 inhibition. Rainey et al
No full textBackground:
CDC7 kinase is required for activation of licensed origins of replication during the process of DNA duplication. CDC7 kinase inhibitors interfere with this process, limiting both DNA synthesis and cell proliferation.
Aim:
Identify genes responsible for limiting cell proliferation in response to inhibition of CDC7 using small molecule ATP-competitive inhibitors.
Strategy:
A CRISPR/Cas9 loss of function screen was performed to identify genes that upon loss allow bypass of a proliferation blockade imposed by the CDC7 inhibitor, XL413.
Data:
Represents source data for main figures and supplemental items in support of the Manuscript 'ATR restrains DNA synthesis and mitotic catastrophe in response to CDC7 inhibition', Rainey et al.
Data collection, interpretation and findings are addressed in the manuscript
Rainey, James M. - An inaugural dissertation on acute metritis
No full textHandwritten inaugural dissertation on acute metritis by James M. Rainey, of Nashville, Tennessee.Inaugural dissertation; no. 62
Homegoing Services For Mrs. Gwendolyn M. Rainey
No full textFuneral program for Mrs. Gwendolyn M. Rainey, born March 23, 1918 and died January 24, 1990. The funeral was held Monday, January 29, 1990 at St. Paul United Methodist Church, officiated by Reverend Robert E. Felder, Pastor. Funeral arrangements were made through Lewis Funeral Home and she was buried in Cemetery No. Three in San Antonio, Texas
ATR restrains DNA synthesis and mitotic catastrophe in response to CDC7 inhibition. Rainey et al
No full textBackground:
CDC7 kinase is required for activation of licensed origins of replication during the process of DNA duplication. CDC7 kinase inhibitors interfere with this process, limiting both DNA synthesis and cell proliferation.
Aim:
Identify genes responsible for limiting cell proliferation in response to inhibition of CDC7 using small molecule ATP-competitive inhibitors.
Strategy:
A CRISPR/Cas9 loss of function screen was performed to identify genes that upon loss allow bypass of a proliferation blockade imposed by the CDC7 inhibitor, XL413.
Data:
Represents source data for main figures and supplemental items in support of the Manuscript 'ATR restrains DNA synthesis and mitotic catastrophe in response to CDC7 inhibition', Rainey et al.
Data collection, interpretation and findings are addressed in the manuscript
M. Kochavi, A. F. Rainey, I. Singer, R. Giveon, A. Demsky Aphek-Antipatris 1974-1977. The Inscriptions
No full textCaquot André. M. Kochavi, A. F. Rainey, I. Singer, R. Giveon, A. Demsky Aphek-Antipatris 1974-1977. The Inscriptions. In: Syria. Tome 57 fascicule 1, 1980. p. 331
Psychobiology of anxiety and anxiety disorders
No full textPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142764/1/Rainey-NessePsychobioAnx-PCNA-1985.pd
Haloplasmatales
No full textHa.lo.plas.ma.ta’les. N.L. n. Haloplasma, type genus of the family; suff. -ales, ending denoting an order; N.L. fem. pl. n. Haloplasmatales, the Haloplasma order. The order Haloplasmatales was circumscribed on the basis of phylogenetic analyses of 16S rRNA gene sequences. The order currently includes only the family Haloplasmataceae and its single genus Haloplasma. It is composed of Gram-negative staining, wall-less, non-spore-forming, pleomorphic cells. Strictly anaerobic. Strictly organotrophic. Denitrifying and fermentative. MK-4 is the major respiratory quinone. Otherwise, the description of the order is the same as for the family Haloplasmataceae. Type genus: Haloplasma Antunes, Rainey, da Costa and Huber 2008a, 2476VP (Effective publication: Antunes, Rainey, Wanner, Taborda, Pätzold, Nobre, da Costa and Huber 2008b, 3586)
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