1,721,038 research outputs found
A basic introduction to single particles cryo-electron microscopy
Full text linkIn the last years, cryogenic-electron microscopy (cryo-EM) underwent the most impressive improvement compared to other techniques used in structural biology, such as X-ray crystallography and NMR. Electron microscopy was invented nearly one century ago but, up to the beginning of the last decades, the 3D maps produced through this technique were poorly detailed, justifying the term “blobbology” to appeal to cryo-EM. Recently, thanks to a new generation of microscopes and detectors, more efficient algorithms, and easier access to computational power, single particles cryo-EM can routinely produce 3D structures at resolutions comparable to those obtained with X-ray crystallography. However, unlike X-ray crystallography, which needs crystallized proteins, cryo-EM exploits purified samples in solution, allowing the study of proteins and protein complexes that are hard or even impossible to crystallize. For these reasons, single-particle cryo-EM is often the first choice of structural biolo..
Ciclo riproduttivo e biometria in Tapes philippinarum (Adams e Reeve, 1850) dell'Alto Adriatico durante un ciclo annuale.
No full textData–driven classification of landslide types at a national scale by using Artificial Neural Networks
Full text linkClassification of landslide type is an essential step in risk management, although is often missing in large inventories. Here we propose a novel data-driven method that uses easily accessible morphometric and geospatial input parameters to classify landslides type at a national scale in Italy by means of a shallow Artificial Neural Network. We achieved an overall True Positive Rate of 0.76 for a five-class overall classification of over 275,000 landslides as (1) rockfall/toppling, (2) translational/rotational slide, (3) earth flow, (4) debris flow, and (5) complex landslide. In general, the model performance is very good in the entire national territory, with large areas reaching F-score higher than 0.9. The method can be applied to any polygonal inventory, as those produced by automatic mapping procedures from Earth Observation imagery, in order to automatically identify the types of landslides
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dynamic and spatial approaches to assess the impact of geographical indications on rural areas
Full text linkThe paper explores the role of Geographical Indications (GIs) in promoting the economic development of European regions. We consider all NUTS3 regions of Italy, France, and Spain between 1993 and 2014, and 728 GIs.. Our research aims to empirically assess the impacts of GIs on labor productivity and employment, for the agricultural and industrial sectors. We rely on a dynamic panel model and considere the spatial variation of the data. The main results show that GIs generate a positive impact on employment, both in the short and the longrun. Moreover, we find that the impact of GIs is not limited to the province where they are produced, but also triggers sizable spillover effects. Our results have important policy implications for further economic research
Preliminary Design of the European Advanced Reusable Satellite EARS
No full textToday there is an increased demand to recover payloads from Space. Moreover, environmental concerns are pushing towards reusability of Space Assets. The European Advanced Reusable Satellite (EARS) project aims to tackle both issues by designing a low-cost small spacecraft capable of supporting a variety of small experiments for orbital missions potentially longer than one year. The satellite should be able to operate and return to Earth autonomously, taking advantage of an inflatable drag device and heatshield. After recovery, it should be reused with minimal refurbishment. Moreover, it must be compatible with common launch vehicles secondary payload attachments. The spacecraft is based on a current microsatellite platform with the addition of the heatshield, a powerful and controllable liquid propulsion system, and a recovery system based on a guided parafoil with helicopter mid-air retrieval. This paper explains the philosophy and approach behind the EARS concept and describes the preliminary design of the mission, the spacecraft and its main subsystems
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