9 research outputs found

    Characteristics of Children and Young Adults with Marfan syndrome and aortic root dilatation in a randomized trial comparing atenolol and losartan therapy

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    Characteristics of Children and Young Adults with Marfan syndrome and aortic root dilatation in a randomized trial comparing atenolol and losartan therap

    Classical supravalvar aortic stenosis and peripheral pulmonary stenosis

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    Supravalvar aortic stenosis as well as peripheral pulmonary stenosis are rare forms of congenital heart disease, which occur, however, relatively frequently in association. This article reports and discusses the classical findings of SVAS and PPS upon clinical examination and imaging in a sixyear-old girl that presented with repeated respiratory tract infections and failure to thrive.peer-reviewe

    Cardiovascular malformations: Changes in prevalence and birth status, 1972-1990

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    Through an ongoing hospital-based active malformation surveillance program, we identified cardiovascular malformations (CVMs) in 3.3 per 1,000 liveborn and stillborn infants, and fetuses from pregnancies terminated electively during a 15-year period. We excluded the children of mothers who had planned delivery elsewhere, but were transferred for care of anomalies that had been detected in prenatal screening, Birth status changed markedly during the study with a significant increase in elective terminations of fetuses with a CVM from 0 to 22% (P < 0.01 based on a test for trend). The proportion of liveborn infants with CVMs decreased from 90% to 73% (P < 0.01); the frequency of stillbirths did not change, During the study period, there was a significant increase in the prevalence of CVMs in all births (P < 0.01) and elective terminations (P < 0.01), The increase in liveborn prevalence was not statistically significant (P = 0.08), Stillborn prevalence was unchanged. The number of mothers having prenatal ultrasonography (P < 0.01 for trend) and amniocentesis (P < 0.01 for trend) increased steadily. There were significant increases in the pro-portion of mothers having any ultrasound examination (P < 0.01 for trend), the number of initial ultrasound examinations occurring in the second trimester (P < 0.01 for trend), and the proportion of mothers having amniocentesis (P < 0.01 for trend), There was a significant increasing trend in the proportion of mothers who were 35 years and older (10% in 1972-1974, 26% in 1988-1990, P < 0.01), This hospital-based active surveillance program suggests that more frequent elective terminations had a significant effect on overall birth prevalence of CVMs, This trend would not have been detected by most other surveillance systems which determine prevalence of common birth defects from birth certificates and other forms of administrative reporting, and exclude elective terminations of pregnanc

    A aderência à medicação em pacientes portadores de transtorno mental em uma unidade básica de saúde.

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    Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina. Departamento de Saúde Pública

    Atenolol versus losartan in children and young adults with Marfan's syndrome

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    BACKGROUND : Aortic-root dissection is the leading cause of death in Marfan's syndrome. Studies suggest that with regard to slowing aortic-root enlargement, losartan may be more effective than beta-blockers, the current standard therapy in most centers. METHODS : We conducted a randomized trial comparing losartan with atenolol in children and young adults with Marfan's syndrome. The primary outcome was the rate of aortic-root enlargement, expressed as the change in the maximum aortic-root-diameter z score indexed to body-surface area (hereafter, aortic-root z score) over a 3-year period. Secondary outcomes included the rate of change in the absolute diameter of the aortic root; the rate of change in aortic regurgitation; the time to aortic dissection, aortic-root surgery, or death; somatic growth; and the incidence of adverse events. RESULTS : From January 2007 through February 2011, a total of 21 clinical centers enrolled 608 participants, 6 months to 25 years of age (mean [+/- SD] age, 11.5 +/- 6.5 years in the atenolol group and 11.0 +/- 6.2 years in the losartan group), who had an aorticroot z score greater than 3.0. The baseline-adjusted rate of change (+/- SE) in the aortic-root z score did not differ significantly between the atenolol group and the losartan group (-0.139 +/- 0.013 and -0.107 +/- 0.013 standard-deviation units per year, respectively; P = 0.08). Both slopes were significantly less than zero, indicating a decrease in the degree of aortic-root dilatation relative to body-surface area with either treatment. The 3-year rates of aortic-root surgery, aortic dissection, death, and a composite of these events did not differ significantly between the two treatment groups. CONCLUSIONS : Among children and young adults with Marfan's syndrome who were randomly assigned to losartan or atenolol, we found no significant difference in the rate of aorticroot dilatation between the two treatment groups over a 3-year period

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    iatlij fain Attn •JttttM \ TWENTY-THIRD YEAR. EIGHT PAGES. PALO ALTO, CAL.. WEDNESDAY. MAY ,..,15.EIGHTPAGES.NO.105.SEEELGRILSTOVOINOURWINDOWItIsacombinationgrillsndstovebroils,fries,bollssndtoaststwooperationatthesametime,oneaboveandtheotherbelowtheglowingcolls.Operatesfromsaylampsocket.RegularpricefS,REDUCEDTO, ..,15. EIGHT PAGES. NO. 105. SEE EL GRILSTOVO IN OUR WINDOW It Is a combination grill snd stove—broils, fries, bolls snd toasts—two operation* at the same time, one above and the other below the glowing colls. Operates from say lamp socket. Regular price fS, REDUCED TO 3.35 DURING HOTPOINT WEEK MAY 3-8 No specie! dishes required. T"se ordinary utensils tgrantte ware Included) on top; Ior broiling, etc., an extra deep underdlab is provided As economic*!, convenient rooking device st a remarkably low price. Remember, S3.3~> for one week only. Get yours today. PALO ALTO HARDWARE CO. »SA*4 **« »**sam5APERFECTGEMNewlyCompletedBungalowHardwoodfloorsinlivingroomanddiningroom.Insidefinishthebestweknowhow.wallstinted.Shadesandelectricfixturescomplete.ASMALLPAYMENTDOWNJustenoughtoshowgoodfaiththebalancelikerentandyouareontherightroad.IFTHISISTOOSMALLforyourfamilywehavealargerone,andnobetterbuilthouseanywhereonthesametermsSEEJOHNDUDFIELD01ticPhonePaloAlto21HomePhone".« •am 5* A PERFECT GEM Newly Completed Bungalow Hardwood floors in living room and dining room. Inside finish the best we know how. walls tinted. Shades and electric fixtures complete. A SMALL PAYMENT DOWN—Just enough to show good faith—the balance like rent—and you are on the right road. IF THIS IS TOO SMALL for your family we have a larger one, and no better built house anywhere—on the same terms SEE JOHN DUDFIELD 01 tic- Phone Palo Alto 21 Home Phone ".« 300 for a lot 60x1 50 in Palo Alto Six blocks from Station THE UNIVERSITY REALTY CO. Palo Alto—Han Fraadeeo. Fertilizers In*- ip Mi -. Tree Sprays. I"t. . CoviiU-real lime i ..I'l Powder 1 nl m.i.. *s t.-ln*. Tohecco i .-*.if "40" Arsvc-natr I-end Nitrate of Soda I'..-i.i- 1 ii.nr I-awn l.nlurt Cottonseed Meal llorde-aax Ml store In-1..*.tie I tnu 1-|nn Mn.e-Sulplnir Solution rovtilt-ra-sl Sulphur Atomic Sulphur W. 0. Horabin *-**" Hamilton Avenue. "■IH IN I. P. A. oo. "Do It Now PAINT" PALO ALTO PAINT Co. Contracting Painters and Paper Hangers We carry ready mixed paints or mixed to order. Oils. Varnishes, disss and Wall Paper Silveroid Roofing Phone 460 L |223 University Ave. Felt Soles The new materials for soles. We are showing some specially nice styles in women's pumps and low shoes with the new feature. 3^v*3^C5~ Vacation Duds! OlTIS.i .-I/1THSSI- "SHORT SIIIRTS. K.I Ah IK. KTI'. INIIKSTRITTO THI XKK — SILK A.iKXTS. WIIMKVK SILK (-OATH from Sll. The Regent PHONE 3 HtEK 1-EIalVKlttKS. Home or Hart, thttatber Jt Mars Clothes, "Klirtirst" guaranties-. I Hose evi',-iiiafeil •( >i«r slurs- TAXI? • l-iio.NK 0 15 AMiRt'S taai M-niin: ttp|-*.«(.e Depot. Autos For Hire seven and Five I'saset -louring Can aad Tails 25c BARGAIN One-acre home; sli-room buaga* low, adjoining city limits; forty (nil hearing fruit trees. l'rtre 13,1100; eaay terms. Have a client with from 1,000 to 13,000 to loan on Orat-class mort* Rages. J. J. Morris 100 Initrrsiij Ave., p.],. Alto Take tho Hatter} Boc-tof- Advice t's i-lii'iijH-i to let the doctor keep your storage battery In good health, than to let It die of neglect and have tn buy a new one or pay a big repair bill WllUrd Battery Expect, al ■i"-1-' >t.ir& Phone 978K. 801 High St. Fl RST National Bank The l-odge. established three years sgo by E. II. Mitchell '12. haa been granted a charter hy Phi Kap- |ia Sigma and will henceforth be ranked among the other nineteen fralernlilea on the campus It ts planned to have the Installation take place Immedlately preceding com. mencement. Ram'a Head Society announces the election to membership of M. P, Oelela H. W P. Bacon gr' J. W. Bennett 1... W. B. Curtis 16. B. m. Levy l« aad P. O Solon If.. SUP'TTEMPLETON LIST CHIPPIE IS RE-ELECTED OUT TODAY For Ninth Time Receives Sump, Palo Alto Students Are Among of Approval of Hii Professional ! Contributors to Big Issue of Work Stanford Comic Welt Qualified as Man. as Judge | Miss Margery Baily and James of Teschera. as Disciplinarian ' M. Wallace Authors of and Athletic Adviser Clever Cartoons The board of education reorganised last night by re-electing Walter Hays president and J. A. Tall aecre- tirv j. c. Templeton was re-elect' ed superintendent of srhools for tbe year 191.1-1 a*. This is tbe ninth consecutive elec- Hon of *t,lr. Templeton ns hesd of the Palo Alto schools and will mwet with ihe approval of a large majority of the people of the dlslrlrl. The au- Iterlnteniieucv of i,...,'■ in a college town l» never n sinecure, tt is be- -et with dirtieiilties that mtul be met with the nimoi-t tart and Rood Judgment. Mr. Templeton'a continued • ii.ti-M In this poaltlon Is an Indication ot his blah quail (test ion fur the place. There has been a widespread feeling of dissatisfaction wllh tbe re- aulta achieved by public schools J. C. Templeton throughout the i-oimlri. New demands are being made a-onnlnntl.-- DpOfl the schools. Vocational training. 1 nn,min lul training, thr sciences, the modern languages, me- j-hanical and free-hand drawing, economics, music, kindergarten work, physical culture, all Ihese and other subjects are demanded, nnd si the same lime more Intensive study of eadlnc. writing snd arlthmcllr 1- Inslsted upon by critics of Ihe schools. Mr. Tcmpleton's efforts t«i meet the Incresslng demands of parents have been successful to a degree that Is commented upon by other superintendents In the slate and hy visiting teachers. It may fstrly be aald that a better system of school* cannot be found In California tbar Pslo Alto schools taken ss a whole. Su|ierlntenclcnt Ite-i-ia-lble The board of education hss pur sued tor years Ihe wise i-ollry of electing the teachers who nre recommended hy the sti|ierlnteinlent. Thi* makes him responsible for Ihe careful Investigation Of Ihelr professional qualification*, and eventually responsible for the work done In the -arlous departments. Mr. Temple- ton's recommendations have usually been Justified by the result*. This aystem of giving Ihe appointive power lo the superintendent, the board retaining the veto (tower, has been adopted to advantage In the leading school systems of the eoiin- tr> nnd has worked to the !*est ad- vantage. Nothing I* more deatru - live or Rood order or onthiMinsin for educational progress than a division of authority and a consequent lack or loyalty of the leaching corps to the head of the system. No Reform School Method**. Mr. Templeton Is regarded as an „Jclenl disciplinarian, his polLrr running In the direction of prevenl- The last number of the Chaparral. Stanford's comic patter. Just oft* The ; Times' press, made He n|fp*-aranee [-today at the university and the Palo Alto bookstores It Is a large Issue with a four- color 1 u vet and contains many prose, verse and art contributions. The frontispiece is the picture of a pretty coed In a cap nud gown, entitled "A Ciredtiale hy Request." wllh a trlolel verse It |s from the bruab of Miss llniel Clark '15, who Is also the author of two nth contributions. Miss Margery Bailey of Pslo Alto contribute* s full-page cartoon with one of her Inimitable verses. J. M. Wallace '17, also of Pslo Alto, con tributes severs) cartoons of an unusual nature. "Observations ot a Misogynist" Is the title of a scries of quips at the eipciiae of the fair sex. A critique of the Kngllsh Club play "Sherwood" by .1. C Crome deals with ibe Alfred Noyes' dmnia In » keenly searching manner. The last page of Ihe hook Is devoted tn a picture .of tbe present editor giving over his sledge tn 11. M l-n '16. Ihe new Chappie This Is an annual custom of the mngnrlne ee seeaaeeeeeseessae....... Ing trouble rather than curing tt after It happens. Visits lo Ihe schools rev en I n disposition on ibe part of high school students nnd the younn- er children to devoir themselves to business volunlnrlly without reform- ss'hool methods or repressive measures. \VI*4* \ I hla** la (amtnl The athletic vlrlorles of the blgb school have been marked by parent nnd ti'i.-i-t.i as nn in.li .' nm of 1 u hcilc-Mittie ntlltiide existing between nhideins and teachers. Student lire required lit he iu*nllc|enl In their i-Millies before Ihey can he ni'icplecl ns members of any organization rep resenting Palo Alio High School. Sti|ier|ntendenl Templeton |s one of Ihe founders of the California In lerscholssllc Federation, thai regit tales sports for high schools through' out the slate. Palo Alio lielong* to ihe North Coast section of the C. I P- and of tbls section Mr. Templeton In president. The first state field inaset nt Kn-siio recently lltiii irnleci the orderly workings of Ihe federation nnd proves tluit the ortgl nalor of the federation iierformed a service lo Ihe whole alate. B1 nally high school athletic* will probably require special suiiervlslun by tbe state board of education, the meanwhile Ihe C. I F. Is Ihe nest best way lo hsndle Ihe sllus- tlon. In a proper educational spirit Al Ihe stale learhern association. Superintendent Templeton takes rank wltb the I,est men of Ibe state. (Continued on Page Right.) HEALTH REPORT IS ISSUED Officer H. F. Gray Submits Statement telling Conditions in Palo Alto Special Attention Is Called to Unusually High Grade of Milk in Local Dairies The re (tort of Health Officer Orav for April, submitted to the board of public safety at lu regular monthly meetlag. shows Ihe health conditions In Palo Alto to be excellent. There were thirty-three cases of communicable diseases during the month, of which Iwentv-elnht were whooping cough; Ihe one ense of malaria was contracted In Panama. There were eight births during* the month, four boys snd four girls. Two deaths were recorded, both male .iiged -sit nnd ft? years. During Ihe month seventeen diagnostic tests were made and tlilrtr- slx sample- •*! milk and cream were tested Thirteen nuisance* wee* abated and sis cases are pending. The health officer mad four sanitary. Ave dairy and ten food Inspections, and twenty-eight for communlcabl* diseases; the sanitary - Inspector mitde I.t41 Unitary, eight dairy and two food itr-|.i- tsi.ti- All meal markets and bakeries were recorded, and In every rasa there wan a marked Improvement. The report anyn: "In practically all cases the hreadsluffs and meals are handled In a rredltably cleanly man ner, the principal difficulty confronting the local dealers being the lack of specially constructed sanitary buildings. The milk supply continues up Ua standard In case of one dairy supplying ""Inspected/' milk the acor* w*s ■•-. per cent, and with Improvements now being made . this acort* will he advsnre-d During the month lir. 11. W. Chap- pel gsvn two lectures snd demonstrations tn teachers of the public schools on the ekrly diagnosis of communicable disease* of children. "Thus assisting the teachers Io ree- ognlse cases nt the earliest possible moment, (he teachers can be of the greatest naslstance tn the health des- pnrlment without In any way adding lo Ihe burden of Ihelr work," says Ihe report The police department reported hut one arrest during tbe month, a violation of a city ordinance, tbe arrested person being given a slxty- dsy sentence In the county Jail. J. S. Elliott, practical dry cleaner, 108 Circle, solicits your patronage. See my adjl on page V I'hone 467K. Jt-rt-Jt**—Advl. Miss Harker's School Tales-hnneJJO B-*nHisf anal Das ~*h-*>l for G:fh*~|SSj Atttri.tr l |a mlleff Mi.si , lli.fi.-i'.. Science, An* aad Crafts lnleinvr-1-atr anal Primary f.tttn Mnnlnaorl Opjim.rtit -i--!ifi| lacro bc|ini Jan. A, 1915 MARQUEE THEATER Ileal Ventilation House ol Salety. Sumptuously Furnished Heac Our 10,000 'Fotoplayer* Tuesday and Wednesday WILLIAM FARNUM "Samson" <Nol a Biblical play.) Tbls |n Die IIva*.reel production UuU the critics maid w>* * "*».ii»*»Ii* Ing" good pn tun-—the term tits toumctly. "PATHES WEEKLY" . li*n-*.i'i\ M (Ml CHILDREN' 10 (TVW FIRST SHOW 7:15- SECOND 8*45- t»l It MIHIC AI/tlNK IS WORTH MANY TIM*-* THE PRICE t»P ADMlKriHlN'. In "IF WE MUST DIE" said Spsrtacus. addressing the Roman gladiator, "let us die together." Spartacun should bare reflected that THERE IS NO IF ABOUT DYING Tbe only certain thing In an uncertain life la the ultimate csll for tbe undertaker. The '.rim Reaper t* alwsys on the Job. Your turn may come next. Think it over, and If your conclude " that this I* true, ask UK aboot the excellent i-ollcle* offered by the San Francisco Life Insurance Company WILLIAM S. MILLER. Agent. I'hone IM. P. <». Bos Mo. I'alo Alio Santa Fe Lumber Co. Mayiield. Cal. I'hone J68

    Design of a didactic sequence of Spanish language in the framework of the principles of Universal Design for Learning

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    En la actualidad la educación requiere de constantes innovaciones para responder a la diversidad en el aula, donde todos los niños, las niñas y los jóvenes tengan igualdad de oportunidades de participación. Es por ello, que nace la presente investigación que tiene como objetivo general, el diseño de una secuencia didáctica para el grado cuarto en el marco de los principios del Diseño Universal para el Aprendizaje, que fortalezca el acceso y la participación de todos los estudiantes con o sin discapacidad. El Diseño Universal para el aprendizaje (DUA) es un camino pedagógico que responde a prácticas diversificadas, basadas en los diferentes estilos de aprendizaje, la realidad que viven los estudiantes, el contexto, las necesidades y los intereses. La metodología para esta investigación se enmarca en el diseño de participación acción con un enfoque cualitativo, la muestra fue de once estudiantes y cuatro maestras del grado cuarto de una institución privada en Floridablanca. Las fases de la investigación fueron cuatro. La primera, la fase de planeación, que contempló el diseño de una entrevista semiestructurada dirigida a las maestras y un taller para caracterizar las necesidades e intereses de los estudiantes. La segunda, la fase de acción, permitió la ejecución de la entrevista y el taller. La fase tercera, observación, tuvo en cuenta el análisis y la triangulación de los resultados, los cuales sugieren responder a prácticas diversificadas. La cuarta fase, de reflexión, tuvo como fin el diseño de la secuencia didáctica en el marco del Diseño Universal para el Aprendizaje en el área de lengua castellana y la validación de expertos de la secuencia didáctica, la cual sirve como modelo para planear en el marco del DUA. Por último, una de las conclusiones de la investigación es que el Diseño Universal para el Aprendizaje, brinda múltiples experiencias a través de varias vías de acceso, para que todos los estudiantes desde su propio estilo individual alcancen el máximo potencial del conocimiento.Resumen 9 Introducción 11 Capítulo I: Planteamiento del problema 14 Descripción del Problema de investigación 14 Pregunta de investigación. 17 Objetivos de la investigación 17 Objetivo General 17 Objetivos específicos 17 Supuestos cualitativos 18 Justificación de la investigación 18 Capítulo II. Marco de referencia 22 Antecedentes 22 Antecedentes regionales 22 Antecedentes nacionales 26 Antecedentes Internacionales 29 Marco conceptual 33 Diseño Universal de aprendizaje (DUA) 33 Currículo Flexible 36 La inclusión como proceso 38 Reconocimiento de la diversidad 40 Secuencia didáctica universal 41 Estudiante con discapacidad desde el modelo social 43 Barreras, tipos de barreras y ajustes razonables 45 Proyecto Individual de Ajustes Razonables (PIAR) 47 Marco legal 48 Capítulo III. Metodología 51 Método y tipo de investigación 51 Fases de investigación 52 Población y muestra 54 Aplicación de técnicas e Instrumentos de recolección de datos. 56 Validación de los instrumentos 60 Aspectos éticos 61 Capítulo IV. Resultados y análisis 62 Resultados de la entrevista semiestructurada 62 Resultados del diario de campo realizado en el taller 69 Análisis de los resultados 71 Resultado de la validación de la secuencia didáctica 79 Diseño de secuencia didáctica 80 Capítulo V. Conclusiones y recomendaciones 101 Conclusiones 101 Recomendaciones 104 Referencias 106MaestríaNowadays, education requires constant innovations to respond to diversity in the classroom, where all children and young people have equal opportunities for participation. For this reason, the present research was born with the general objective of designing a didactic sequence for the fourth grade within the framework of the principles of Universal Design for Learning, which strengthens access and participation of all students with or without disabilities. The Universal Design for Learning (UDL) is a pedagogical path that responds to diversified practices, based on the different learning styles, the reality that students live, the context, needs and interests. The methodology for this research is framed in the design of action participation with a qualitative approach, the sample consisted of eleven students and four teachers of the fourth grade of a private institution in Floridablanca. There were four phases of the research. The first, the planning phase, involved the design of a semi-structured interview with the teachers and a workshop to characterize the needs and interests of the students. The second, the action phase, allowed for the execution of the interview and the workshop. The third phase, observation, took into account the analysis and triangulation of the results, which suggested responding to diversified practices. The fourth phase, reflection, was aimed at the design of the didactic sequence in the framework of the Universal Design for Learning in the area of Spanish language and the validation by experts of the didactic sequence, which serves as a model for planning in the framework of the UDL. Finally, one of the conclusions of the research is that the Universal Design for Learning provides multiple experiences through various access routes, so that all students, from their own individual style, reach the maximum potential of knowledge.Modalidad Presencia
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