5 research outputs found
Obstacle Detection for Start-Inhibit and Low Speed Driving
No full textThe work described in this paper has been developed in the framework of the integrated project APALACI-PReVENT, a research activity funded by the European Commission to contribute to road safety by developing and demonstrating preventive safety technologies and applications. The goal of the system presented in this work is the development of a vision system for detecting potential obstacles in front of a slowly moving or still vehicle. When the vehicle is still, a background subtraction approach is used assuming that the background keeps stationary for a limited amount of time; thus, a reference background is computed and used to detect changes into the scene. A different approach is used when the vehicle is moving. The system, by means of inertial sensors, can detect ego-motion and correct background information accordingly. A temporal stereo match technique, able to detect obstacles in moving situations, completes the system. According to experimental results, the proposed algorithm can be useful in different automotive applications, requiring real-time segmentation without assumptions on background motion
Software Architecture for Process Management Using RFID Technology in the Fashion Supply Chain: Engineering, Development and Experimental Validation
No full textL'impiego della tecnologia di identificazione in radio frequenza (RFID) e del codice elettronico di prodotto (EPC) a supporto della logistica offre numerosi benefici tra cui la tracciabilità e la piena visibilità delle merci nella supply chain, sebbene produca un notevole incremento nella complessità dei dati da gestire.
Al fine di ottenere il controllo completo sul flusso delle informazioni è necessario disporre di una infrastruttura software adeguata che governi al meglio la complessità del sistema RFID e che offra garanzie di stabilità ed affidabilità.
In quest'opera viene ampiamente descritta l'architettura software a sostegno dell'impianto realizzato all'interno del progetto denominato "RFID Fashion Pilot", il primo progetto pilota italiano di sperimentazione con l'obiettivo di valutare i vantaggi nell'adozione della tecnologia RFID e dello standard EPC nella supply chain fashion.
Il progetto è frutto della collaborazione tra il laboratorio RFID Lab e alcune delle aziende di spicco dell'industria Fashion italiana.
I punti di forza dell'architettura sviluppata vertono sull'adozione degli standard di riferimento introdotti da EPCglobal per la realizzazione del cosiddetto EPCglobal Network, una rete di elaborazione che unisce tutti gli attori di una stessa supply chain al fine di ottimizzare i processi logistici a partire dalla condivisione delle informazioni.The use of radio frequency identification technology (RFID) and the electronic product code (EPC) to support Logistics offers many benefits, such as the traceability and the full visibility of goods in the supply chain, although it produces a significant increase in the complexity of data to manage.
In order to gain control over the flow of information it is necessary to have an appropriate software infrastructure able to handle the most of the complexity of the RFID system and to provide guarantees for stability and reliability.
In this work it is widely described the software architecture supporting the project called "Fashion RFID Pilot", the first Italian experimental pilot project with the goal of evaluating the impacts of RFID technology and EPC adoption in the fashion supply chain.
The project is developed in partnership between the RFID Lab and some of the leading companies of the italian fashion industry.
The developed architecture's strengths is based on the adoption of standards introduced by EPCglobal to realize the so-called EPCglobal Network, a network that combines all the actors of the same supply chain to optimize business processes by sharing information.embargoed_2013060
Homeomorphism versus isomorphism for varieties
No full textAbstractIt is well known that a morphism onto a weakly normal algebraic variety that is both birational and a universal homemorphism is an isomorphism of varieties. in this note, the author shows that a birational morphism onto a weakly normal algebraic variety X with a continuous inverse is necessarily an isomorphism of varieties if and only if X had no one-dimensional components. Thus the characterization of the weak normalization of a variety X as the largest variety that is birationally homeomorphic to X is only valid in the absence of one-dimensional components. All varieties are over a fixed algebraically closed field
Temporal and spatial relations between patents and scientific journal articles: the case of nanotechnologies
No full textPatent citations have been widely used in order to study inter-technology and science-technology relations. The present work aims at: i) exploring time relations and distance between technical/innovative activities and scientific knowledge, using journal articles citations in patents as a proxy; ii) exploring the origin of the knowledge cited in patents. The study is performed on a field particularly relevant both on the scientific and technological side, that of nanosciences and nanotechnologies. In parallel a field less on the edge of research (polymers) is studied in order to compare results and shed better light on what is happening in nanotech. Studied items show a common behaviour and a higher rate of citations and a shorter time lag between citing patents and cited articles for nanotechnologies rather than for polymers. Knowledge cited in patents shows in many cases a common origin with that of citing documents. Conclusions on these behaviours are drawn.Patent-research relations, Patent, Journal Article, Nanoscience, Nanotechnologies, Polymers, Technological trajectories, Data mining, Innovation, Knowledge diffusion
Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis
No full text\ua9 2020, The Author(s).The αvβ6 integrin plays a key role in the activation of transforming growth factor-β (TGFβ), a pro-fibrotic mediator that is pivotal to the development of idiopathic pulmonary fibrosis (IPF). We identified a selective small molecule αvβ6 RGD-mimetic, GSK3008348, and profiled it in a range of disease relevant pre-clinical systems. To understand the relationship between target engagement and inhibition of fibrosis, we measured pharmacodynamic and disease-related end points. Here, we report, GSK3008348 binds to αvβ6 with high affinity in human IPF lung and reduces downstream pro-fibrotic TGFβ signaling to normal levels. In human lung epithelial cells, GSK3008348 induces rapid internalization and lysosomal degradation of the αvβ6 integrin. In the murine bleomycin-induced lung fibrosis model, GSK3008348 engages αvβ6, induces prolonged inhibition of TGFβ signaling and reduces lung collagen deposition and serum C3M, a marker of IPF disease progression. These studies highlight the potential of inhaled GSK3008348 as an anti-fibrotic therapy
