2,268 research outputs found
Lunette a“Paesi”di Augusto Rosa nel Chiostro di Sant’Andrea delle Fratte a Roma
No full textAlla luce delle precedenti ricerche condotte dall'autrice sulla figura del pittore Agusto Rosa, figlio di Salvatore, viene riconosciuta la sua mano in 4 lunette con scene di San Francesco di Paola nel chiostro di Sant'Andrea delle Fratte a Rome, dove compaiono data e sigla
Rezension zu: Ilaria Bignamini/Clare Hornsby, Digging and Dealing in Eighteenth-Century Rome. With additional research by Irma Della Giovampaola and Jonathan Yarker (New Haven and London 2010)
No full textCaratteirizzazione dell'evoluzione comportamentale di un modello animale emiparkinsoniano indotto da 6-OHDA
No full textThe establishment of a correlation between behavior and structure changes is essential to understand disorders diagnosed on the bases of “behavioral” disturbances. Among these
Parkinson’s Disease (PD) has been traditionally considered as a "pure" movement disorder secondary to focal degeneration of dopaminergic (DAergic) neurons in the Substantia Nigra pars compacta (SNc). However, in recent years the clinical phenotype has been revised, showing that PD is a multisystem neurodegenerative disorder with motor and non-motor features showing different time evolutions. Several animal models have been employed in experimental studies concerning the pathogenetic mechanism of PD and therapeutic strategies.
A commonly used animal model of PD is the unilateral injection of 6-hydroxydopamine (6-OHDA) into the SNc of rodents capable of inducing a stable nigrostriatal lesion within 3 weeks. The time-course of the anatomical, metabolic and behavioral changes that occur at the late-phase has been extensively studied. However, despite a large body of evidence has been provided about the 6-OHDA PD model, some crucial questions concerning the early-phase PD lesioned-rat behavior remain unanswered. Indeed, it is very interesting to study the early molecular and functional changes time-course observed in the emergence of the Parkinsonian lesion in the standard 6-OHDA-induced by high-DAergic depletion model and whether they might be predictive of the severity of the lesion. In this PhD thesis we investigated the early-phase time course of behavioral and structural changes in the nigrostriatal pathway during the degeneration of SNc neurons induced by
intranigral injection of 6-OHDA (8 μg/4 μL) in the right hemisphere. In particular, we investigated if early (1 to 7 days post-lesion) motor behavioral deficits can be fully characterized and whether they may be predictive of the severity of the DAergic lesion at later time points (14, 21 days post lesion). To determine the time-course of the emergence of potential spontaneous motor deficits, we modified the Tail Suspension Test, here indicated as Tail Suspension Swing Test (TSST).We compared the TSST results to those obtained with the standard rotation test in the Open Field Test (OFT).We recorded spontaneous and apomorphine-induced behavioral asymmetries using a modified implementation of the TSST and the standard OFT, before and following 6-OHDA injection. The accuracy of the 6-OHDA lesion was evaluated by means of ex vivo whole-brain high-resolution Magnetic Resonance Imaging (MRI). The DAergic lesion was then evaluated by immunohistochemical staining for tyrosine hydroxylase (TH) to detect TH-immunoreactive (TH-ir) neurons and fibers in the SNc and the striatum(ST), respectively. Moreover, we studied the behavioral features of the animals after 21 days of 6-OHDA-induced lesion of the DAergic nigrostriatal system, providing a T-Pattern Analysis (TPA) of the sequential organization of the behavior, in terms of sequences detected and features. Our main experimental result is that TSST is more sensitive to reveal the spontaneous motor asymmetries. On the other hand, the results of the TSST and OFT tests after acute and repetitive apomorphine treatment, well correlated with immunohistochemical striatal DA staining and nigral DAergic neuronal loss seen at the different time-points. The TSST can therefore be useful for the selection of those animals to study early pathophysiological mechanisms, that occur from the first day after the 6-OHDA lesion and new neuroprotective strategies without the confounding apomorphine administration. Moreover, our TPA results at 21 days post-lesion show for the first time that the temporal structure and fine characteristics of behavioral sequencing are altered in the late phase of the PD rodent model obtained with a unilateral SNc injection of 6-OHDA
Data of cost-optimal solutions and retrofit design methods for school renovation in a warm climate
No full textAbstract"Efficient Solutions and Cost-Optimal Analysis for Existing School Buildings" (Paolo Maria Congedo, Delia D’Agostino, Cristina Baglivo, Giuliano Tornese, Ilaria Zacà) [1] is the paper that refers to this article. It reports the data related to the establishment of several variants of energy efficient retrofit measures selected for two existing school buildings located in the Mediterranean area. In compliance with the cost-optimal analysis described in the Energy Performance of Buildings Directive and its guidelines (EU, Directive, EU 244,) [2,3], these data are useful for the integration of renewable energy sources and high performance technical systems for school renovation. The data of cost-efficient high performance solutions are provided in tables that are explained within the following sections.The data focus on the describe school refurbishment sector to which European policies and investments are directed. A methodological approach already used in previous studies about new buildings is followed (Baglivo Cristina, Congedo Paolo Maria, D׳Agostino Delia, Zacà Ilaria, 2015; IlariaZacà, Delia D’Agostino, Paolo Maria Congedo, Cristina Baglivo; Baglivo Cristina, Congedo Paolo Maria, D’Agostino Delia, Zacà Ilaria, 2015; Ilaria Zacà, Delia D’Agostino, Paolo Maria Congedo, Cristina Baglivo, 2015; Paolo Maria Congedo, Cristina Baglivo, IlariaZacà, Delia D’Agostino,2015) [4–8]. The files give the cost-optimal solutions for a kindergarten (REF1) and a nursery (REF2) school located in Sanarica and Squinzano (province of Lecce Southern Italy). The two reference buildings differ for construction period, materials and systems.The eleven tables provided contain data about the localization of the buildings, geometrical features and thermal properties of the envelope, as well as the energy efficiency measures related to walls, windows, heating, cooling, dhw and renewables. Output values of energy consumption, gas emission and costs are given for a financial and a macro-economic analysis.This data article provides 288 and 96 combinations for REF1 and REF2, respectively. The output values are obtained using the software ProCasaClima 2015v.2.0
Studio del fitoplancton della laguna di Grado e Marano per la valutazione dello stato di qualità delle acque di transizione
No full textE’ stata studiata la distribuzione spaziale e temporale dei popolamenti fitoplanctonici in relazione ai principali parametri ambientali nella laguna di Grado e Marano (Friuli Venezia Giulia) nel biennio 2008-2010, applicando procedure e metodi statistici di analisi multivariata per la comprensione della dinamica del fitoplancton e la valutazione dello stato di qualità delle acque di transizione in vista dell’applicazione della Direttiva 2000/60/C
Author Correction: Gluten consumption and inflammation affect the development of celiac disease in at-risk children
No full textThe original version of this Article contained an error in the spelling of the authors Renata Auricchio, Ilaria Calabrese, Martina Galatola, Donatella Cielo, Fortunata Carbone, Marianna Mancuso, Giuseppe Matarese, Riccardo Troncone, Salvatore Auricchio & Luigi Greco which were incorrectly given as Auricchio Renata, Calabrese Ilaria, Galatola Martina, Cielo Donatella, Carbone Fortunata, Mancuso Marianna, Matarese Giuseppe, Troncone Riccardo, Auricchio Salvatore & Greco Luigi. The original article has been corrected
Designing and representing the Anthropocene: a challenge for designers, planners and philosophers
No full textThis contribution relates the outcomes of the international conference "The Ecological Turn", in which the theme of the Anthropocene was discussed at two levels: as an emergency in its actuality and as a threshold, a possibility of going "beyond the Anthropocene". The involvement of architects, philosophers, designers, practitioners and researchers brought multiple lines of thinking and action on permaculture, on new ways of designing the territory, of seeing relationships that were previously hidden, of thinking through the multiple reasons for radical and innovative lifestyles, thinking about the same ontological status of things and the professions of designing
Environmental policies and social impacts. Suggestions from Europeans cities
No full textAre we really sure that green and sustainable are always good for everyone? Ilaria Beretta tries to go beyond the rhetoric of sustainability to understand more deeply the interconnection between economy, society and environment in urban contexts, in the belief that only empirical research and the analysis of data can lead to a correct reading, which is as objective as possible, of the complex reality in which we live. The author, through a comparison between European and U.S. American cities, focuses in particular on policies related to climate change and land use, showing how these, if not properly monitored in their social effects, risk contributing to the tightening of social inequalities, through processes such as ecological and green gentrification. The volume is structured in three parts. In the first section, she illustrates the main European Union’s sustainability and environmental urban policies, focusing on climate change and land use strategies. The second chapter provides a conceptual framework through the environmental justice paradigm, as it applies in Europe and in U.S. Finally, the third chapter offers an empirical analysis of ecological and green gentrification processes, comparing American and European realities, and highlighting how context-specific differences can have profound effects on the manifestation (or not) of these phenomena
Lo scrittoio imaginifico. Volti e risvolti di d'Annunzio narratore
No full textIl volume affronta alcuni aspetti della proteiforme produzione narrativa dannunziana, rivolgendo particolare attenzione allo sperimentalismo della stagione ‘notturna’, interpretata alla luce delle fasi articolate che, già a partire dal Piacere, concorsero alla sua progettazione, nelle scelte contenutistiche come nelle soluzioni stilistiche e retoriche.
Una lettura orientata e selettiva, sia dal punto di vista metodologico che interpretativo, quindi, che si è avvalsa altresì della critica tematica e della comparatistica per dotare della debita sonorità talune voci delle donne che attorniavano lo scrittoio del Vate, nel proposito di farle emergere dal silenzio
"L'albergo" nell'officina poetica di Giovanni Pascoli
No full texta cura di Rosa Giulio, Donato Salvatore e Annamaria Sapienz
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