1,721,163 research outputs found

    Information Categorization and Generalization: a study on the role of serotonin transporter knockout in rats

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    Contains fulltext : 230656.pdf (Publisher’s version ) (Open Access)Radboud University, 24 maart 2021Promotores : Homberg, J.R., Roozendaal, B.160 p

    Emotional arousal effects on object recognition memory: role of amygdala-insular cortex interactions

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    Contains fulltext : 206067.pdf (Publisher’s version ) (Open Access)Radboud University, 03 september 2019Promotor : Roozendaal, B. Co-promotor : Nadif Kasri, N

    Emotional modulation of memory. Mechanisms underlying strength and accuracy of memory.

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    Contains fulltext : 144039.pdf (Publisher’s version ) (Open Access)Radboud Universiteit Nijmegen, 05 oktober 2015Promotor : Roozendaal, B. Co-promotores : Aschrafi, S., Atsak, P

    Constructing knowledge: semantic memories in mice

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    Contains fulltext : 203521.pdf (Publisher’s version ) (Open Access)Radboud University, 17 juni 2019Promotor : Roozendaal, B. Co-promotores : Battaglia, F.P., Genzel, L.K.E

    Unravelling the behavioural and molecular hallmarks of Spinocerebellar Ataxia type 17 (SCA17). Studies on a transgenic rat model

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    Contains fulltext : 215969.pdf (Publisher’s version ) (Open Access)Radboud University, 13 februari 2020Promotores : Homberg, J.R., Roozendaal, B. Co-promotor : Harst, J.E. van de

    Toward tailored treatments: Understanding biological stress regulation to personalize therapy for posttraumatic stress disorder

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    Contains fulltext : 325469.pdf (Publisher’s version ) (Open Access)Posttraumatic stress disorder (PTSD) can develop after a traumatic event. Current therapies are not always effective. To improve future treatment outcomes, this dissertation focuses on the biological stress system. It shows that people with high levels of early-life stress (a predictor for PTSD from later trauma) have a different balance in their stress system; this is reflected in stress-related molecules. Furthermore, it expands our understanding of safety learning. In PTSD treatment, safety learning is key: it results in ‘extinction’ of fear. Relapse, however, often occurs from trauma reminders outside the context of therapy. My research provides insight into the brain mechanisms underlying this process. Finally, it presents a study design to test whether a short stress system “boost” might support safety learning in PTSD, and how this effect may depend on individual differences in the stress system. Together, these studies move personalized PTSD care a step closer.Radboud University, 13 november 2025Promotores : Hermans, E.J., Verkes, R.J., Hendriks, G.J., Roozendaal, B.272 p

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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