1,720,969 research outputs found
New peptide useful for inhibiting virus, bacteria and fungi and preventing and/or treating HIV infection and/or for eradication of HIV virus from viral reservoirs in individuals suffering from HIV
No full textPCT/IB2012/05042
Delayed progression to AIDS in HTLV-I/HIV-1 coinfected intravenous drug users
No full textDelayed progression to Aids in Htlv-Ii/Hiv-1 coinfected intravenous drug user
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
New peptide having specific amino acid sequence with antiviral and antimycotic activity, useful in the treatment or prevention of HIV infection, and for eradication of HIV virus from viral reservoirs in individuals suffering from HIV
No full textNOVELTY - A peptide having specific amino acid sequence with antiviral and antimycotic activity, is new.
USE - In a medical treatment; in the treatment or prevention of HIV infection; and for eradication of HIV virus from viral reservoirs in individuals suffering from HIV or in therapy for AIDS (claimed).
ADVANTAGE - The peptide exhibits antiviral and antimycotic activity; exhibits very low cytotoxicity, and very high stability; exhibits good antimycotic activity, tested in particular on fungi particularly aggressive and commonly active in immunocompromized patients such as patient suffering from AIDS; and exhibits exceptional set of features which make them suitable for medical use in the therapy against HIV infection.
DETAILED DESCRIPTION - A peptide having amino acid sequence containing 20 amino acids (SEQ ID NO: 1), as given in the specification with antiviral and antimycotic activity, is new. INDEPENDENT CLAIMS are included for the following:
(1) new nucleotide sequence coding for the peptide of (SEQ ID NO: 1);
(2) a pharmaceutical composition comprising an antiviral peptide of (SEQ ID NO: 1) as active principle and carrier; and
(3) a pharmaceutical kit for concomitant or sequential administration comprising at least one aliquot of the antiviral peptide of (SEQ ID NO: 1) as active principle in a carrier and at least one aliquot of at least one of the active principles selected from: peptide having amino acid sequence containing 28 amino acids (SEQ ID NO: 2), 15 amino acids (SEQ ID NO: 3), as given in the specification, nucleoside inhibitors; non-nucleoside inhibitors; reverse transcriptase inhibitors; integrase inhibitors; viral protease inhibitors; antimycotics; antibacterials; and virus-host cell fusion process inhibitors
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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