1,721,002 research outputs found

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Forward precision medicine: Micelles for active targeting driven by peptides

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    Precision medicine is based on innovative administration methods of active principles. Drug delivery on tissue of interest allows improving the therapeutic index and reducing the side effects. Active targeting by means of drug-encapsulated micelles decorated with targeting bioactive moieties represents a new frontier. Between the bioactive moieties, peptides, for their versatility, easy synthesis and immunogenicity, can be selected to direct a drug toward a considerable number of molecular targets overexpressed on both cancer vasculature and cancer cells. Moreover, short peptide sequences can facilitate cellular intake. This review focuses on micelles achieved by self-assembling or mixing peptide-grafted surfactants or peptide-decorated amphiphilic copolymers. Nanovectors loaded with hydrophobic or hydrophilic cytotoxic drugs or with gene silence sequences and externally functionalized with natural or synthetic peptides are described based on their formulation and in vitro and in vivo behaviors

    A Tele-Education Oriented Experiment based on an Integrated Terrestrial/Satellite Network

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    The paper presents the architectural solutions and the experimental results of the integration of two networks, a Campus terrestrial Network and a Geographic satellite Network, which have been designed and deployed by the CNIT (Italian National Consortium for Telecommunications). The two networks were developed in different contexts and use a different approach, but they have the common aim to demonstrate the feasibility of a tele-teaching system using standard and ad-hoc software application. The result of the integration is a nation-wide distributed tele-education network with a large number of clients. It is composed of an ATM/ADSL network within a Campus and of a TCP/IP satellite network, which acts as a backbone for the geographic distribution. On one hand, the ATM portion of the network allows reserving specific network resources for each flow (even if it is not necessary in the experiment performed due to the high capacity available), on the other hand, through a satellite network, whose bandwidth is limited to 2 Mbits/s, a TCP/IP suite is used. TCP/IP protocols offer a best-effort service but, in this case, a guaranteed service should be offered. There are two methods in the literature to reserve resources in a TCP/IP-based network: the Integrated Services and the Differentiated Services. The former has been chosen in this environment, on the base of previous experimental studies and of the test-bed dimension. The experiment of integration has been investigated by using both subjective and objective performance parameters. Network users (students) have been asked to fill in reports to measure the Perceived Quality of Service, in order to get a Mean Opinion Score (MOS) about the level of user perception of the overall tele-teaching service. Measurements of packet loss and jitter have been also performed in order to assess the Quality of Service of the integrated network

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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