1,721,122 research outputs found
Isolated ovarian relapse of pre-b acute lymphoblastic leukemia.
No full textJ Pediatr Adolesc Gynecol. 2009 Aug;22(4):e65-8. Epub 2009 Jun 2.
Isolated ovarian relapse of pre-B acute lymphoblastic leukemia: a case report.
Berretta R, Barone A, Rolla M, Bertolini P, Nardelli GB.
SourceDepartment of Obstetrics and Gynecology, University of Parma, Parma via gramsci 14 -43100, Italy. [email protected]
Abstract
BACKGROUND: Acute lymphoblastic leukemia is a malignant disease of the bone marrow in which early lymphoid precursors proliferate and replace normal marrow hematopoietic cells, resulting in a marked decrease in the production of normal blood cells.
CASE REPORT: We report a case of isolated ovarian relapse 7 years after the primary diagnosis in a patient, who was seemingly in clinical remission following unilateral ovariectomy and second-line chemotherapy.
CONCLUSION: In contrast to testicular relapse, ovarian relapses in acute lymphoblastic leukemia are rarely reported. Surgical removal of the mass followed by chemotherapy is the therapeutic standard
Laparoscopic management of gynaecological cancer in pregnancy.
No full textJ Obstet Gynaecol. 2010 Apr;30(3):319-21.
Laparoscopic management of gynaecological cancer in pregnancy.
Berretta R, Rolla M, Ceccaroni M, Benassi G, Modena AB, Nardelli GB.
SourceDepartment of Obstetrics and Gynecology, University of Parma, Parma, Italy. [email protected]
In pregnant women, the incidence of cervical cancer is estimated at around 1 in 10,000 (Amant et al. 2009), while the rate of adnexal masses varies between 2% and 4% (Amant et al. 2009). Approximately 6% of all operated adnexal masses are malignant and the incidence of ovarian cancer during gestation fluctuates from 1 in 10,000 to 1 in 100,000. The purpose of this study was to report our experience with laparoscopy in pregnant women for the management of gynaecological cancer
Incidence of port-site metastases after laparoscopic pure management of borderline ovarian tumors : a series of 22 patients
No full textEur J Gynaecol Oncol. 2009;30(3):300-2.
Incidence of port-site metastasis after laparoscopic management of borderline ovarian tumors: a series of 22 patients.
Berretta R, Rolla M, Patrelli TS, Gramellini D, Fadda GM, Nardelli GB.
SourceDepartment of Gynecology, Obstetrics and Neonatology, University of Parma, Parma, Italy. [email protected]
Abstract
PURPOSE: The aim of this work was to evaluate the incidence of port-site metastasis in patients undergoing laparoscopy for borderline ovarian carcinoma (BOT).
METHODS: Twenty-two patients who underwent laparoscopy from 2004 to 2008 for BOT were evaluated retrospectively.
RESULTS: In 15 patients an ultraconservative procedure with enucleation of the annexal neoplasia was carried out, while in five (23%) unilateral salpingo-oophorectomy was performed and in two cases (9%) bilateral salpingo-oophorectomy was done.
CONCLUSION: The literature data report few cases of port-site metastasis in BOT patients. Residual cutaneous metastases have been reported to occur within 12 months from the first surgery, generally in association with serous histology. In our analysis, we found 17 out of 22 cases of serous BOT, three mucinous and two endometriod. In no case was cutaneous metastasis revealed after an average of 30 months of follow-up
Pelvic lymphadenectomy in endometrial cancer: our current experience.
No full textEur J Gynaecol Oncol. 2009;30(5):536-8.
Pelvic lymphadenectomy in endometrial cancer: our current experience.
Patrelli TS, Berretta R, Rolla M, Vandi F, Capobianco G, Gramellini D, Bacchi Modena A, Nardelli GB.
SourceDepartment of Gynecology, Obstetrics and Neonatology, University of Parma, Italy. [email protected]
Abstract
OBJECTIVE: Lymph node involvement is the single most important factor in the prognosis of endometrial cancer, because it is predictive of locoregional and distant metastases. The purpose of our study was to determine whether lymphadenectomy is useful in the surgical staging of endometrial cancer and if it may help establish a more accurate prognosis and reduce the need for postoperative therapy in patients without surgical complications.
STUDY DESIGN: We conducted a retrospective study on 55 patients with diagnosis of endometrial cancer.
RESULTS: Surgical staging of patients undergoing pelvic lymphadenectomy (47/55) showed that 59.6% of cases (n = 28) had Stage I cancer (IA in 4, IB in 16, IC in 8), 17.02% (n = 8) Stage II (IIA in 3, IIB in 5), 21.2% (n = 10) Stage III (IIIB in 5, IIIC in 5), and 2.1% (n = 1) Stage IVA. In the remaining eight patients with a very high anesthesiologic risk (ASA 4), surgical staging was incomplete because they underwent only node palpation.
CONCLUSION: In conclusion, as we wait for the sentinel lymph node technique to demonstrate satisfactory results and be standardized also for endometrial cancer, we believe that surgical lymph node dissection plays a crucial role in debulking this type of cancer. When performed by a good surgical oncology team, it does not entail a significantly increased operative risk
Randomised prospective study of abdominal wall closure in patients with gynaecological cancer.
No full textAust N Z J Obstet Gynaecol. 2010 Aug;50(4):391-6.
Randomised prospective study of abdominal wall closure in patients with gynaecological cancer.
Berretta R, Rolla M, Patrelli TS, Piantelli G, Merisio C, Melpignano M, Nardelli GB, Modena AB.
SourceDepartment of Obstetrics and Gynecology, University of Parma, Italy. [email protected]
Abstract
BACKGROUND: Median laparotomy is the most common approach to the abdominopelvic cavity in patients with gynaecological tumours.
AIMS: The primary endpoint of the study was to evaluate the onset of incisional hernia. The secondary endpoint was to evaluate the onset of infection, wound dehiscence, wound infection, and scar pain during the post-operative period.
METHODS: A total of 191 patients were eligible for the study. They were divided into three groups. Group A underwent en bloc closure of the peritoneum and fascia with Premilene suture, Group B en bloc closure of the peritoneum and fascia with Polydioxanone suture, and Group C separate closure of the peritoneum and fascia with single stitches of Ethibond suture. Statistical analysis was performed using the Statistical Software Package for Social Sciences 12.0.
RESULTS: Group A and Group B comprised 63 patients, and Group C included 65 patients. The three groups proved homogeneous on statistical analysis (P > 0.05). The statistical analysis did not reveal significant differences between the different suture types and techniques with respect to the incidence of incisional hernia (P > 0.05).
CONCLUSION: In our study, the incidence of incisional hernia was 8%. Randomised patients were homogeneous for sample size and risk factors. No significant differences were found between suture types or techniques. Currently, there is no suture material or technique that can be considered superior to others. When possible, we believe that the best way to prevent incisional hernia is to preserve the integrity of the abdominal wall using minimally invasive techniques
Vaginal versus abdominal hysterectomy in endometrial cancer: a retrospective study in a selective population
No full textInt J Gynecol Cancer. 2008 Jul-Aug;18(4):797-802. Epub 2007 Oct 18.
Vaginal versus abdominal hysterectomy in endometrial cancer: a retrospective study in a selective population.
Berretta R, Merisio C, Melpignano M, Rolla M, Ceccaroni M, DE Ioris A, Patrelli TS, Nardelli GB.
SourceDepartment of Gynecology, Obstetrics and Neonatology, University of Parma, Parma, Italy. [email protected]
Abstract
The purpose of this study was to analyze the outcome of vaginal and abdominal hysterectomy for the treatment of early-stage endometrial cancer in a selected group of elder patients. This retrospective study analyzed a total of 154 patients: 113 (group I) underwent vaginal surgery and 41 (group II) underwent laparotomy. In both groups, we investigated the following parameters: intra- and postoperative complications, mean operative time, mean hospital stay, disease-free survival (DFS), overall survival (OS), and time of local or retroperitoneal recurrence. Medically compromised patients were significantly more frequent in the vaginal surgery group (P = 0.005), and the operative duration in this group was significantly shorter (P = 0.01). Intra- and postoperative complications, along with local and distant recurrence, did not show a statistically significant difference in the two groups. Total survival in the two populations, 85% at 5 years, did not reach statistically significant difference either in terms of DFS or in terms of OS. Vaginal surgery compared to traditional abdominal approach is feasible also in patients with high surgical risk; it does not require general anesthesia, abolishes abdominal trauma correlated to laparotomy, and allows a quicker reprise of the bladder and rectal function; therefore, it achieves high eradication rates and low intra- and postoperative morbidity rates
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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