3,545 research outputs found
Alexandre Vinet, La vérité n'a point de couture. Réflexions et aphorismes tirés des agendas. Transcription, introduction et notes de Bernard Reymond, éditions l'Age d'homme, Lausanne, 1983
No full textVœltzel René. Alexandre Vinet, La vérité n'a point de couture. Réflexions et aphorismes tirés des agendas. Transcription, introduction et notes de Bernard Reymond, éditions l'Age d'homme, Lausanne, 1983. In: Revue d'histoire et de philosophie religieuses, 64e année n°3, Juillet-septembre 1984. pp. 325-326
TRIM9 is specifically expressed in the embryonic and adult nervous system
No full textThe TRIM family members are defined by the presence of the tripartite motif (RING, B-box and coiled-coil domains or RBCC). They have been implicated in a variety of processes, such as regulation of development and oncogenesis. We report the expression analysis of a member of this family, TRIM9. Its expression is mainly confined to the central nervous system. The developing neocortex, the dorsal thalamus, the midbrain, the basal area of the hindbrain and spinal cord show high level of expression during embryogenesis. In adult brain, TRIM9 is detected in the Purkinje cells of the cerebellum, in the hippocampus, and in the cortex
La filosofía del derecho de Alexandre Kojève
No full textThis article is a presentation of Alexandre Kojève’s philosophy of law, exposed in his Esquisse d’une phénoménologie du droit (1981). Little attention has been paid to this work. So there is a gap that has to be filled with a critical reflection of its strengths. Among them, undoubtedly, we count the fact that Kojève is introducing a conception of international justice that casts a singular light on current debates about cosmopolitanism and globalization. According to this author, citizenship is the key element of the process of global expansion of the juridical sphere. In sum, Kojève’s philosophy is useful to reflect upon the contrast between the juridical and the political, which is the basis for all philosophy of law, in order to achieve world peace and international justice.Este artículo es una presentación de la filosofía del derecho de Alexandre Kojève contenida en su Esquisse d’une phénoménologie du droit (1981). La poca atención que dicha obra ha recibido es un vacío que debiera llenarse con una reflexión crítica de sus puntos fuertes. Entre ellos destaca una concepción de la justicia internacional que proyecta una luz muy singular sobre los actuales debates en torno a la globalización y el cosmopolitismo. A ojos de este autor, la ciudadanía es el elemento clave para aquilatar la expansión global de lo jurídico. En suma, Kojève aparece como un valioso referente en la labor de pensar la contraposición entre lo jurídico y lo político que está en la base de toda filosofía del derecho, con la aspiración al logro de la justicia internacional y la paz mundial en el horizonte
Reconfiguração do consensualismo contratual: as ações tituladas nominativas e os limites à transmissão
No full textPartimos da evolução histórica do consensualismo contratual salientando os
principais carateres que, nos diversos momentos históricos, se foram evidenciando.
Numa segunda etapa exploramos os fundamentos dogmáticos do modelo de
transmissão contratual assumido pelo legislador e a sua viabilidade no sistema
jurídico global, em particular, no direito dos valores mobiliários. Constatamos a
crescente necessidade na prática mercantil e inevitabilidade no sistema jurídico
global da admissibilidade da existência de contratos de compra e venda de natureza
meramente obrigacional. Num terceiro momento desenvolvemos os principais
aspetos do regime jurídico aplicável às ações tituladas nominativas fora do mercado
regulado, em particular, os principais limites à transmissão, enquanto instrumentos/barreiras ao consensualismo contratual.We start from the historical evolution of contractual consensualism emphasizing the
main aspects that, in different historical moments, were showing up. In a second
stage we explore the dogmatic foundations of the transmission model contractual
assumed by the legislator and its viability in the global legal system, in particular, in
securities law. We note the growing need in commercial practice and inevitability in
the global legal system the admissibility of the existence of contracts of sale purely
obligatory. In the third stage we develop the main aspects of the legal regime
applicable to nominative titled actions outside the regulated market, in particular,
the main limits to the transmission, as instruments / barriers to contractual
consensualism
Mlx, a new Max-Like bHLHZip family member: the center stage of a novel transcription factors regulatory pathway?
No full textThe Myc proto-oncogene family members have been identified as the cellular homologs of the transforming oncogene of avian retroviruses. They encode central regulators of mammalian cell proliferation and apoptosis, and they associate with the bHLHZip protein Max to bind specific DNA sequences and regulate the expression of genes important for cell cycle progression. The other family members, Mad1, Mxi1, Mad3, Mad4 and Rox (Mnt) antagonize their activities. The Mads and Rox compete with Myc in heterodimerizing with Max and in binding to the same specific target sequences. These Mads:Max and Rox:Max dimers repress transcription through binding to the mSIN3 corepressor protein and by tethering histone deacetylase-containing complexes to the DNA. In a screen for Rox interactors we isolated Mlx, a bHLHZip protein previously identified in a screen for Mad1 interactors. In the present work we extend the known dimerization partners of Mlx by demonstrating its ability to interact with Rox. Moreover, we show that contrary to previous reports Mlx is able to homodimerize and to bind E-box sequences at low concentration levels. The possible role of Mlx in an emerging regulatory pathway and acting parallel to the Max driven network is discussed
“Era por Alexandre tod’esto demostrado”: ¿pruebas verídicas y pruebas engañosas en el Libro de Alexandre?
No full textEl Libro de Alexandre es un texto de s. XIII, que se escribió en la España medieval. En este escrito, el autor pretende demostrar que, en el Alexandre, algunas de las situaciones que se ponen a prueba son aceptadas, pero eso no significa que el macedonio gane la prueba. El articulo esta dividido en tres apartados. En el primero, el autor da cuenta de la historia textual de la obra y también dedica ciertas líneas al Estado de la cuestión del texto; mientras que, en la segunda parte, nos guía a conceptos etimológicos de los términos prueba, evidencia y demás. En el tercer apartado se centra en algunas pruebas expuestas en el Libro de Alexandre.The Libro de Alexandre is a literary work, written during the medieval Spain. In this paper, the author tries to demonstrate that, carefully reading the L.A, some of the situations that are set as proves are accepted, but it does not mean that Alexander can be a victor. This paper is divided in three sections: firstly, the author tells the textual history of the L.A and, then, tries to update the State of art: on the other hand, in the second part, the author offers meanings about terms as: prueba and evidencia. Finally, the author focuses on certain passages contained in the Libro de Alexandre that can be taken as failed proves
Mixing the Immiscible: Improvisation within Fixed-Media Composition
No full textThis paper will explore ways in which mastered improvisation practice, with the studio as an instrument, is a proposed avenue to bridge the historical dichotomy between what Ted Gioia describe as ‘the aesthetics of perfection’ and ‘the aesthetics of imperfection’. It is proposed as a way to re-embody fixed music, as experimented by the author through the composition of his last fixed-media work. This will be put in the context of a wider trend observed amongst the current emerging generation of composers interested in the aesthesics of the work, by opposition to the previous generations that placed the value of the work in its poietics. The vital and primal importance of practice outcome as practice-based research’s main document will also be advocated for, as these trends are happening in the laboratory of live music
Alexandre de Rhodes (1593?-1660)
No full textBiografia do jesuíta francês Alexandre de Rhodes (1593?-1660), missionário na Cochinchina (Vietname) e no Tonquim. Autor do Dicionário Anamita-Português-Latim (1651), Rhodes foi uma figura central no choque de interesses entre o Padroado Português e as ambições diplomáticas e políticas da França na Indochina e na China.Biography of the French Jesuit Alexandre de Rhodes (1593?-1660), missionary in Cochinchina (Vietnam) and Tonkin. Author of the Anamita-Portuguese-Latin Dictionary (1651), Rhodes was a central figure in the clash of interests between the Portuguese Padroado and France's diplomatic and political ambitions in Indochina and China.info:eu-repo/semantics/publishedVersio
La Clerecía de "Alexandre"
No full textEl artículo reflexiona sobre la educación que recibe Alexandre “El grande” a manos de su profesor Aristóteles, retratado en el “Libro de Alexandre”; a continuación analiza las disciplinas que compusieron dicho programa con el interés de proponer una interpretación de la lista de las siete artes liberales mencionadas. Este artículo ofrece una visión de las diferentes maneras en las que los textos reflejan la “clerecía” del protagonista así como de otros personajes, incluyendo el anónimo autor de los mismos. Cualquiera que se dedique a las mencionadas artes liberales será glorificado y Alexandre se presenta él mismo como modelo ideal de un príncipe en quien la nobleza y al inteligencia van unidas, una defensa clara de la “clerecía” como fuente fundamental de toda excelencia. This article deals with the education imparted on Alexander the Great by Aristotles, as portrayed in the “Libro de Alexandre”, analyzes the disciplines and proposes an interpretation of the list of the seven liberal arts mentioned therein. This article also offers an encompassing view of the different ways in which the text reflects the “clerecía2 of the protagonist as well as that of the other characters, including the anonymous author himself. Anyone who dedicates him or herself to the aforementioned liberal arts is thereby glorified, and Alexander presents himself as the ideal model of a prince in whom nobility and cleverness are joined, in a clear defense of the “clerecía” as the fundamental source of all excellence
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