352 research outputs found
Mariia: The Chronicle of a Life
Last year, I proposed to complete a translation of Ukrainian author Ulas Samchuk’s novella Mariia. The process of translating and researching has been both more challenging and more rewarding than I anticipated. I completed the translation of the first section of Mariia, along with a research paper discussing the symbolism of the first section
Influence of functionalized nanoparticles of different size, material, and surface properties on cellular machinery
Title: Influence of functionalized nanoparticles of different sizes, material, and surface properties on cellular machinery Author: Mariia Uzhytchak Department: Department of Optical and Biophysical Systems, Institute of Physics of the Czech Academy of Sciences Supervisor: Mgr. Oleg Lunov, PhD., Department of Optical and Biophysical Systems, Institute of Physics of the Czech Academy of Sciences Abstract: Last few decades nanoparticles (NPs) have emerged as promising tools in the nanomedicine field as theranostic agents. The influence of functionalized nanoparticles with different sizes, material compositions, and surface properties on cellular machinery has attracted significant research interest. Understanding these influences is crucial for the development of safe and effective nanomedicines. This study aims to explore the impact of functionalized nanoparticles on cellular machinery and kinetics. Hereby, the thesis is focused on the importance of gaining knowledge in the field of nanomedicine while considering potential harms associated with nanomaterials application. Keywords: cell culture, cell signaling, cytotoxicity, nanoparticles, drug deliver
Vliv funkcionalizovaných nanočástic různé velikosti, složení a povrchových vlastností na buněčné funkce
Název: Vliv funkcionalizovaných nanočástic různé velikosti, složení a povrchových vlastností na buněčné funkce Autor: Mariia Uzhytchak Oddělení: Oddělení optických a biofyzikálních systémů, Fyzikální ústav Akademie věd České republiky Vedoucí práce: Mgr. Oleg Lunov, PhD., Oddělení optických a biofyzikálních systémů, Fyzikální ústav Akademie věd České republiky Abstrakt: V posledních několika desetiletích se nanočástice (NP) ukázaly jako perspektivní nástroje v oblasti nanomedicíny jako teranostické agenty. Vliv funkčně modifikovaných nanočástic s různými velikostmi, materiálovým složením a povrchovými vlastnostmi na buněčný aparát přitahuje značný výzkumný zájem. Porozumění těmto vlivům je klíčové pro vývoj bezpečných a účinných nanoléčiv. Tato studie si klade za cíl prozkoumat vliv funkčně modifikovaných nanočástic na buněčný aparát a kinetiku. Práce se zaměřuje na získání znalostí v oblasti nanomedicíny s ohledem na potenciální nežádoucí účinky spojené s aplikací nanomateriálů. Klíčová slova: kultivace buněk, buněčné signalizace, cytotoxicita, nanočástice, doručování léčivTitle: Influence of functionalized nanoparticles of different sizes, material, and surface properties on cellular machinery Author: Mariia Uzhytchak Department: Department of Optical and Biophysical Systems, Institute of Physics of the Czech Academy of Sciences Supervisor: Mgr. Oleg Lunov, PhD., Department of Optical and Biophysical Systems, Institute of Physics of the Czech Academy of Sciences Abstract: Last few decades nanoparticles (NPs) have emerged as promising tools in the nanomedicine field as theranostic agents. The influence of functionalized nanoparticles with different sizes, material compositions, and surface properties on cellular machinery has attracted significant research interest. Understanding these influences is crucial for the development of safe and effective nanomedicines. This study aims to explore the impact of functionalized nanoparticles on cellular machinery and kinetics. Hereby, the thesis is focused on the importance of gaining knowledge in the field of nanomedicine while considering potential harms associated with nanomaterials application. Keywords: cell culture, cell signaling, cytotoxicity, nanoparticles, drug deliveryMatematicko-fyzikální fakultaFaculty of Mathematics and Physic
Mikrostruktura a vlastnosti lehké slitiny AZ31 připravené plynulým odléváním mezi válce
Název práce: Mikrostruktura a vlastnosti lehké slitiny AZ31 připravené plynulým odléváním mezi válce Autor: Mariia Zimina Abstrakt: Mikrostruktura hořčíkové slitiny AZ31 připravená metodou plynulého odlévání mezi válce byla studována pomocí světelné a elektronové mikroskopie a mikroskopie atomárních sil a byl testován vliv zvýšené teploty na výslednou mikrostrukturu materiálu. Mechanické vlastnosti byly zkoumány měřením mikrotvrdosti a tahovými zkouškami při relativně nízké rychlosti deformace 10-3 s-1 . Výsledky ukazují, že tažnost studovaného materiálu roste s rostoucí teplotou deformace, avšak v okolí 200 řC se tažnost plynule odlévaného materiálu značně snížila. Tento efekt byl pozorován i u konvenčně odlitého materiálu a je pravděpodobně způsoben změnou deformačního mechanismu indikovaného při této teplotě. Dále byly studovány změny mikrostruktury a mechanických vlastností způsobené intenzivní plastickou deformací. Materiál byl deformován metodou pravoúhlého protlačování rovnostrannými kanály, což vedlo ke značnému zjemnění velikosti zrn a zvýraznění počáteční bazální textury, která je však při následném žíhání téměř zcela potlačena. Poprvé byla také úspěšně použita metoda lisování asymetrickou rýhovanou matricí na stejné slitině. Výsledkem bylo opět zjemnění velikosti zrn, výrazný nárůst mikrotvrdosti...Title: Microstructure and mechanical properties of lightweight structural AZ31 alloy prepared by twin-roll casting method Author: Mariia Zimina Abstract: Microstructure of AZ31 twin-roll cast magnesium alloy was studied using light optical, electron and atomic force microscopy. The effect of annealing temperature on the microstructure was tested. Mechanical properties of a thin magnesium strip were investigated by means of microhardness tests and tensile tests at a relatively low strain rate 10-3 s-1 . Results show that the ductility of the twin roll cast strip increases with increasing deformation temperature, however, a remarkable decrease was observed at about 200 řC. This effect appears also in a conventionally cast ingot of a master alloy and is caused by a change of a deformation mode occurring at this temperature. Moreover, the effect of severe plastic deformation on the microstructure and mechanical properties was studied. Equal channel angular pressing was applied on magnesium strip samples and lead to a significant grain refinement accompanied by an unfavorable strengthening of the initial basal texture, which is effectively suppressed by a subsequent annealing. A constrained groove pressing was for the first time successfully applied on AZ31 twin-roll cast strip leading to an increase of...Katedra fyziky kondenzovaných látekDepartment of Condensed Matter PhysicsFaculty of Mathematics and PhysicsMatematicko-fyzikální fakult
Microstructure and mechanical properties of lightweight structural AZ31 alloy prepared by twin-roll casting method.
Title: Microstructure and mechanical properties of lightweight structural AZ31 alloy prepared by twin-roll casting method Author: Mariia Zimina Abstract: Microstructure of AZ31 twin-roll cast magnesium alloy was studied using light optical, electron and atomic force microscopy. The effect of annealing temperature on the microstructure was tested. Mechanical properties of a thin magnesium strip were investigated by means of microhardness tests and tensile tests at a relatively low strain rate 10-3 s-1 . Results show that the ductility of the twin roll cast strip increases with increasing deformation temperature, however, a remarkable decrease was observed at about 200 řC. This effect appears also in a conventionally cast ingot of a master alloy and is caused by a change of a deformation mode occurring at this temperature. Moreover, the effect of severe plastic deformation on the microstructure and mechanical properties was studied. Equal channel angular pressing was applied on magnesium strip samples and lead to a significant grain refinement accompanied by an unfavorable strengthening of the initial basal texture, which is effectively suppressed by a subsequent annealing. A constrained groove pressing was for the first time successfully applied on AZ31 twin-roll cast strip leading to an increase of..
Quality of care provided to patients with a stoma
1 Abstrakt Autor: Mariia-Luiza Tarasiuk Instituce: Ústav nelékařských studií LF UK v Hradci Králové Název práce: Kvalita poskytované péče u pacientů se stomií Vedoucí práce: Mgr. Dana Vaňková Počet stran: 99 Počet příloh: 2 Rok obhajoby: 2024 Klíčová slova: stomie, kolostomie, ileostomie, urostomie, kvalita ošetřovatelské péče, stomické pomůcky Bakalářská práce se zabývá kvalitou poskytované péče pacientům se stomií. V teoretické části byla uvedena základní fakta týkající se anatomie a fyziologie gastrointestinálního traktu a onemocnění vyžadujících chirurgický zákrok v podobě vytvoření umělého vývodu orgánu. Byly objasněny druhy stomií - kolostomie, ileostomie, urostomie a v souvislosti s nimi byla přiblížena specifika péče o pacienty, kteří prošli tímto zákrokem. Pozornost byla věnována jejich edukaci zaměřené na fyzickou i psychickou přípravu před zákrokem a v průběhu hospitalizace, jež jim byla poskytována ze strany zdravotního personálu, tzn. lékaře a stomické sestry (stomasestry). Informace se týkaly i sebepéče po ukončení hospitalizace s důrazem na správné používání stomických pomůcek. Empirická část obsahuje vyhodnocení kvantitativního výzkumného šetření realizovaného metodikou dotazníkového šetření. Otázky v dotazníku zjišťovaly, jak respondenti hodnotí poskytovanou péči a informovanost v nemocnici...1 Abstract Author: Mariia-Luiza Tarasiuk Institution: Department of Non-medical Studies, Faculty of Medicine, Charles University in Hradec Králové Title: Quality of Care Provided to Patients with a Stoma Supervisor: Mgr. Dana Vaňková Number of pages: 99 Number of appendices: 2 Year of defense: 2024 Keywords: stoma, colostomy, ileostomy, urostomy, quality of nursing care, stoma appliances The thesis deals with the quality of care provided to patients with a stoma. The theoretical part states basic facts regarding the anatomy and physiology of the gastrointestinal tract and diseases requiring surgical intervention in the form of creating an artificial organ outlet. The types of stomas - colostomy, ileostomy, urostomy were explained, and in the connection with those, the specifics of care for patients who have undergone this procedure were discussed. Attention was paid to their education focused on physical and psychological preparation before the procedure and during hospitalization, which was provided by the medical staff, meaning doctors and stoma nurses. The information also concerned self-care after the end of hospitalization, with emphasis on the correct use of stoma appliances. The empirical part contains the evaluation of quantitative research conducted using the survey methodology. The questions in...Department of Non - Medical StudiesÚstav nelékařských studiíLékařská fakulta v Hradci KrálovéFaculty of Medicine in Hradec Králov
Quality of care provided to patients with a stoma
1 Abstract Author: Mariia-Luiza Tarasiuk Institution: Department of Non-medical Studies, Faculty of Medicine, Charles University in Hradec Králové Title: Quality of Care Provided to Patients with a Stoma Supervisor: Mgr. Dana Vaňková Number of pages: 99 Number of appendices: 2 Year of defense: 2024 Keywords: stoma, colostomy, ileostomy, urostomy, quality of nursing care, stoma appliances The thesis deals with the quality of care provided to patients with a stoma. The theoretical part states basic facts regarding the anatomy and physiology of the gastrointestinal tract and diseases requiring surgical intervention in the form of creating an artificial organ outlet. The types of stomas - colostomy, ileostomy, urostomy were explained, and in the connection with those, the specifics of care for patients who have undergone this procedure were discussed. Attention was paid to their education focused on physical and psychological preparation before the procedure and during hospitalization, which was provided by the medical staff, meaning doctors and stoma nurses. The information also concerned self-care after the end of hospitalization, with emphasis on the correct use of stoma appliances. The empirical part contains the evaluation of quantitative research conducted using the survey methodology. The questions in..
President of Crimea. Constitution : Author(s) Autonomous Republic of Xena-Maria
In this essay, two voices are heared, from two women: a certain artist Xena, who talks about her life and its dramas, interwoven with her own experiences from her diaries; and the voice of Maria, who analyzes Xena's life story and her art, diffracted through the prim of the history of 21stC art. Art the outset, "President of Crimea. Constitution", announces its author as Xena-Maria; but it is not yet clear whether the author is one person or two, nor who they are. Is it Maria who writes here, or Xena, or both? Or are they one and the same person? But at the end of the story, which is told rather in a form of certain legends and fairy tales, Maria and Xena turn into one whole, and meaningfully put an ellipsis after the words "to be continued". This reception was specially intended by the artist Maria Kulikovska, author of this essay, in order to protect both herself and the reader from possible persecutions by migration services and goverment officials of various countries, especially Russia. Also, for her it is an opportunity to step aside and analyze her own life and art form a third person, about which, perhaps, a fictional character from her childhood talks - a sensible step for Maria Kulikovska. The step that her creative language conceptually continues is to replicate casts of her own body and establish them in different spaces and contexts. So she fairly confuses the viewer as to where is the truth, and where is fiction; where is herself, and where is her clone - only now, here, she has applied the same trick in her text. This essay tells a very personal story of the life of a human body, a migrant woman in forced relocation, displacements, alienation and persecutions for her views on life and the conduct of society, and for her moral values expressed throught architecture, sculpture, drawings, performances, actions and public statements. Through the prism of geopolitical upheavals, it tells the artist's own story: How her analysis of own body position and boundaries helped her overcome stigma regarding the body of a woman from Eastern Europe, and how art can save and redeem in an unending inner drama.
Author and image categories of the author in journalistic modelling reality (on the material of the pamphlets BY M. Khvylovy)
Памфлети М. Хвильового ефективні журналістські матеріали, функціональне розмежування категорій автор та образ автора на їх основі допомагає
усвідомити особливості публіцистичної комунікації. Сатирик-публіцист аналізує
реальну дійсність, апелює до раціональної сфери читача, допомагає розумово осягнути
негативне; категорія автор представляє конкретно-фактичний план оповіді. Образ памфлетиста скерований до емоційного відчуття реципієнта, діями
в умовно-вигаданому полі оповіді він провокує сміх. Хвильовий-памфлетист це
ерудит, політик, мистецтвознавець, що логічно розмірковує про негативну дійсність, образ автора наділений рисами блазня, який критикує і висміює всіх і все.
Комунікаційний потенціал памфлетів визначається авторським раціональним
осмисленням реальності та емоційним впливом образу памфлетиста.Памфлеты Н. Хвылевого эффективные журналистские материалы, функциональное
разграничение категорий автор и образ автора на их примере помогает
осознать особенности публицистической коммуникации. Сатирик-публицист
анализирует реальную действительность, апеллирует к рациональной сфере читателя,
помогает постигнуть умом отрицательное; категория автор представляет
конкретно-фактический план повествования. Образ памфлетиста устремлен к
эмоциональному ощущению реципиента, действиями в условно-вымышленном поле повествования он провоцирует смех. Хвылевый-памфлетист это эрудит, политик,
искусствовед, который логически рассуждает о негативной действительности,
образ автора наделен чертами шута, он критикует и высмеивает всех и все.
Коммуникативный потенциал памфлетов определяется авторским рациональным
осмыслением реальности и эмоциональным влиянием образа памфлетиста.Pamphlets of M. Hvylyoviy’s is an effective journalistic materials, the functional
distinction between the author and the image of the author on the basis of them helps
to understand the features of journalistic communication. The article aims to trace the
pamphlets of M. Hvylyoviy’s the category of the author and the image of the author and to
determine their functions in the process of journalistic communication; the goal is to show
the opinions of scholars regarding the author and the image of the author; to compare
definition of these concepts in philology and jurnalistilor; to distinguish between the pamphlets
of the characteristics of the author and the author; to explain the functions of the two
categories in journalism.
Category of authorship in the theory of journalism is more common with its definitions
in the literature, timing the author, the image of the author, the image of the narrator, the
researchers use both spheres of creative activity. In the literature highlight the concept
of «the creator of the artwork» as the subject of artistic activity, «the image of the author
» — shows the artist’s own account in his work, «the artist-creator», the interpreter of
life events, the prophet and the mouthpiece of tradition and «the way of the storyteller» —
as a contingent, and not a real author-creator.
Artistic and journalistic works of different nature, which affects the features of the functioning
in them of the author and the image of the author. Artwork drawn to your imaginary
world, is an aesthetic system, autonomous in relation to the real world of the reader, the
artist deliberately departs from verisimilitude, he wants to establish high aesthetic ideals.
Journalistic text represents reality, this documentary system, important for the reader documento
being played. Satirist-publicist analyzes the reality, appeals to the rational sphere of
the reader, helps to understand the mental negative, activates the public; the category of the
author is exactly is the actual narrative terms. The image of a pamphleteer emotional sensations
sent to the recipient, it acts into the quasi-fictional the narrative field, provokes laught.
Hvylyoviy-pamphleteer — is the polymath, politician art critic, pamphleteer embodies the
jester, he mocks, criticizes and makes fun of everyone and everything. Communication potential
of the pamphlets is determined by the author’s rational comprehension of reality and
the negative emotional impact of the image of the pamphleteer
The impact of EU regulations on the Polish legal system in the field of administrative law. The need to create new, special (untypical) entities in Polish administrative law
As an institution, the European Union forces the Member States to adapt to its requirements,
which are the fulfilment of its vision of functioning. The Union does not allow the Member
State to act contrary to its rules. Anyone who wants to belong to the Union should not the
only accent but also implement its provisions in its legal system. This is due to the fact that the
Union wants to be one, a common institution, and not a set of countries that are legally different,
acting in such a way that they are mutually exclusive. Therefore, in specific sectors, the
EU dictates very clear conditions, thus affecting the introduction of specific regulations into a
given legal order, even by creating specific entities. And this is the case in Poland. Therefore,
the main intention of the authors of the article is to show and characterize very clear EU influence
on the creation and operation of new entities in the Polish legal system, in particular in
the Polish administrative law. The main emphasis was put on the creation and functioning of
government agencies in Poland, which EU regulations have a huge impact, among others due
to the transfer of funds for the performance of their individual tasks.The co-author, Kapustina Mariia Alexandrovna, acknowledges Saint-Petersburg State University for
a research grant 26520757
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