1,627 research outputs found
Importance of Glutamate Dehydrogenase (GDH) in Clostridium difficile Colonization In Vivo
No full textCitation: Girinathan, B. P., Braun, S., Sirigireddy, A. R., Lopez, J. E., & Govind, R. (2016). Importance of Glutamate Dehydrogenase (GDH) in Clostridium difficile Colonization In Vivo. Plos One, 11(7), 18. doi:10.1371/journal.pone.0160107Clostridium difficile is the principal cause of antibiotic-associated diarrhea. Major metabolic requirements for colonization and expansion of C. difficile after microbiota disturbance have not been fully determined. In this study, we show that glutamate utilization is important for C. difficile to establish itself in the animal gut. When the gluD gene, which codes for glutamate dehydrogenase (GDH), was disrupted, the mutant C. difficile was unable to colonize and cause disease in a hamster model. Further, from the complementation experiment it appears that extracellular GDH may be playing a role in promoting C. difficile colonization and disease progression. Quantification of free amino acids in the hamster gut during C. difficile infection showed that glutamate is among preferred amino acids utilized by C. difficile during its expansion. This study provides evidence of the importance of glutamate metabolism for C. difficile pathogenesis
Comparison of several author indices for gauging academic productivity
No full textBackground
Many author indices exist to gauge academic productivity. Several of these indices are calculated based upon an author's scholarly publication record, but the measurement methodology to calculate each index varies considerably, and the precise function being used, as well as the end result, is often complex and difficult to assess.
Method
Two straightforward methods to weigh author productivity from the publication and citation record were evaluated as possible means for providing a clearer assessment of scholarly activity. The author characteristic index (termed c-index) assigns author rank for each publication based upon author position. The characteristic prime (c') -index normalizes author rank from author position, so that the total weight per publication is unity. The top 10 scholars with keyword 'celiac disease' in the Google Scholar database were then assessed using these metrics. Rankings according to total number of publications, h-index, and c- and c'-indices were compared, then tabulated along with total papers included for assessment, and mean values per paper for author position, number of authors, citations, and year of publication.
Results
The order of the top ten authors with keyword 'celiac disease' varied substantially depending upon whether the h-index, c-index, or c'-index was used as a gauge. The characteristic indices assign credit to authors according to their position in an author list. The affiliated metrics provided a more complete picture of scholarly activity.
Conclusions
Academic achievement by scholars, based upon quantitative publication characteristics, has recently become of interest for evaluating job candidates, for determining work performance, and for bestowing awards and honors. The characteristic indices as described herein are readily calculated and interpreted, and may improve the assessment of scholarly activity
Scientometric Insights into Research Contributions of Govind Ballabh Pant University of Agriculture and Technology
No full textThis study evaluates the research productivity and impact of Govind Ballabh Pant University of Agriculture and Technology using Scopus data (2001–2021). A total of 4,897 publications receiving 53,059 citations were analyzed with scientometric indicators including AGR, RGR, DT, collaboration measures, authorship, citations, and keywords. Results show a gradual growth in research output, with peak productivity during 2017–2021 and Kumar, A. as the most prolific author (165 publications)
'Humanomics' of Ranade
No full textM.G. Ramrde (1842-1901) was among the pioneering thinkers of India who, wanted modification in classical economics and criticized it because of its abstraction, miscalculation of human nature, and no accounting of socio-cultural environment and religious elements. The present paper aims to study this aspect of his contribution to economic theory in general and to Indian school of economics in particular. We refer to it as 'Humanomics' because he gave the prime importance to diverse human society and culture, its values and beliefs in formulation and application of economic theory.Human Economics, Ethico-economics; Indian economic Thought.
sj-docx-15-pie-10.1177_09544089221107295 - Supplemental material for Unsteady thermally radiative Prandtl fluid flow past a magnetized inclined porous stretching device with double-diffusion, viscous dissipation, and Joule heating
No full textSupplemental material, sj-docx-15-pie-10.1177_09544089221107295 for Unsteady thermally radiative Prandtl fluid flow past a magnetized inclined porous stretching device with double-diffusion, viscous dissipation, and Joule heating by Amar B. Patil, Nalini S. Patil, Vishwambhar S. Patil, Pooja P. Humane and Govind R Rajput in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p
sj-docx-18-pie-10.1177_09544089221078153 - Supplemental material for Dynamics of multiple slip boundaries effect on MHD Casson-Williamson double-diffusive nanofluid flow past an inclined magnetic stretching sheet
No full textSupplemental material, sj-docx-18-pie-10.1177_09544089221078153 for Dynamics of multiple slip boundaries effect on MHD Casson-Williamson double-diffusive nanofluid flow past an inclined magnetic stretching sheet by Pooja P. Humane, Vishwambhar S. Patil, Amar B. Patil, MD. Shamshuddin and Govind R. Rajput in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p
sj-docx-11-pie-10.1177_09544089221078153 - Supplemental material for Dynamics of multiple slip boundaries effect on MHD Casson-Williamson double-diffusive nanofluid flow past an inclined magnetic stretching sheet
No full textSupplemental material, sj-docx-11-pie-10.1177_09544089221078153 for Dynamics of multiple slip boundaries effect on MHD Casson-Williamson double-diffusive nanofluid flow past an inclined magnetic stretching sheet by Pooja P. Humane, Vishwambhar S. Patil, Amar B. Patil, MD. Shamshuddin and Govind R. Rajput in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p
sj-docx-3-pie-10.1177_09544089221107295 - Supplemental material for Unsteady thermally radiative Prandtl fluid flow past a magnetized inclined porous stretching device with double-diffusion, viscous dissipation, and Joule heating
No full textSupplemental material, sj-docx-3-pie-10.1177_09544089221107295 for Unsteady thermally radiative Prandtl fluid flow past a magnetized inclined porous stretching device with double-diffusion, viscous dissipation, and Joule heating by Amar B. Patil, Nalini S. Patil, Vishwambhar S. Patil, Pooja P. Humane and Govind R Rajput in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p
sj-docx-2-pie-10.1177_09544089211050715 - Supplemental material for Thermally and chemically reacted MHD Maxwell nanofluid flow past an inclined permeable stretching surface
No full textSupplemental material, sj-docx-2-pie-10.1177_09544089211050715 for Thermally and chemically reacted MHD Maxwell nanofluid flow past an inclined permeable stretching surface by Amar B. Patil, Vishwambhar S. Patil, Pooja P. Humane and
Nalini S. Patil, Govind R. Rajput in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p
sj-docx-15-pie-10.1177_09544089221078153 - Supplemental material for Dynamics of multiple slip boundaries effect on MHD Casson-Williamson double-diffusive nanofluid flow past an inclined magnetic stretching sheet
No full textSupplemental material, sj-docx-15-pie-10.1177_09544089221078153 for Dynamics of multiple slip boundaries effect on MHD Casson-Williamson double-diffusive nanofluid flow past an inclined magnetic stretching sheet by Pooja P. Humane, Vishwambhar S. Patil, Amar B. Patil, MD. Shamshuddin and Govind R. Rajput in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p
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