858 research outputs found
Defect-related degradation of Deep-UV-LEDs
No full textWith this paper we describe an extensive analysis of the electro-optical degradation of deep ultraviolet
Light-Emitting Diodes emitting at 310 nm, submitted to accelerated stress test. The results obtained
within this study indicate that: (i) high current stress can induce a significant decrease in the optical
power emitted by the LEDs; (ii) optical power decrease is more prominent at low measuring current levels,
indicating that degradation is related to an increase in the concentration of defects, with subsequent
decrease in the radiative efficiency of the active layer; (iii) stress can induce a significant increase in the
operating voltage of the LEDs, due to the increase in the resistivity of the ohmic contacts or p-type semiconductor;
and (iv) after stress, LEDs show a significantly increased green parasitic emission. This result
suggest that stress induced an increase in the defectiveness of the active layer. Information on the location
of the degraded region is achieved by the analysis of the Apparent Charge Distribution curves
obtained by capacitance–voltage measurements
URI Disambiguation in the Context of Linked Data
No full textThe Linked Data initiative has given rise to an increasing number of RDF datasets, many of which are freely accessible online. These resources often arise as a result of database exports; however sufficient consideration may not be given to the unseen implications caused when they are used in the wider context of the Semantic Web. This paper investigates two popular resources, DBLP and DBpedia, and discusses whether the issues regarding identity management and co-reference resolution have been suitably addressed. We find that a large percentage of authors in DBLP have been conflated, and that disambiguation pages have been incorrectly linked using owl:sameAs within DBpedia. Systems for dealing with these issues are presented, and directions are given for future research
Novel data according Will Roger`s phenomenon in stomach cancer patients
No full textDubinina V. G., Lukjanchuk О. V., Lurin A. G., Маshukov А. А., Bilenko А. А., Zgura A. N., Raciborsky D. V., Merlich S. V., Shilin I. V. Novel data according Will Roger`s phenomenon in stomach cancer patients. Journal of Education, Health and Sport. 2016;6(6):185-206. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.55178
http://ojs.ukw.edu.pl/index.php/johs/article/view/3570
The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015).
755 Journal of Education, Health and Sport eISSN 2391-8306 7
© The Author (s) 2016;
This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,
provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License
(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.
This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial
use, distribution and reproduction in any medium, provided the work is properly cited.
The authors declare that there is no conflict of interests regarding the publication of this paper.
Received: 05.05.2016. Revised 25.05.2016. Accepted: 25.05.2016.
Novel data according Will Roger`s phenomenon in stomach cancer patients
Dubinina V. G.1, Lukjanchuk О. V.1,2, Lurin A. G.2, Маshukov А. А.1,2, Bilenko А. А.2, Zgura A. N.2, Raciborsky D. V.2, Merlich S. V.2, Shilin I. V.2
Odessa national medical university1
Odessa regional oncologic center2
Acknowledgments: Supported by the Oncological Department of Odessa Regional Pathology Service.
Summary
Mostly Will Roger`s phenomenon means existence of so-called "jumping" or "jumping over the stages" regional metastases in the stomach cancer patients. N1 in the 6th edition means 16 regional lymph nodes involvement, while the N1 seventh edition – only 1-2 of regional lymph nodes involvement. This means that T1N1Mo \ 6th and T1N1Mo \ 7th - not quite the same, and the survival of the two groups will be different. The study, made on the abdominal oncosurgical department of Odessa Regional Oncology Center, included 188 patients operated for gastric cancer in the period 2007-2011. The study included only radically treated patients. Comparison of survival in patients with gastric cancer between 6th revision groups of 7th has been reviewed. The classification mission is to provide differences in the survival rates between the groups.
Regression multivariate Cox analysis showed that 7th UICC classification showed different capability of stratifying survival groups of UICC N classification (P \ 0.01).
Key words: extended lymphatic dissection, TNM classification, Will Roger`s phenomenon, stomach cancer
MACROECONOMIC STABILITY AND ECONOMIC GROWTH IN CENTRAL AND EASTERN EUROPEAN COUNTRIES: EVOLUTION AND NEW CHALLENGES
No full textThe objective of this article is to analyse the processes of macroeconomic stabilisation in Central and Eastern European countries over the past thirty years (1991-2021), from the inception of market reforms to the present day. At the same time, the author aims to identify patterns and trends in the macroeconomic policies of these countries, which were formed under the influence of radical structural changes, economic cycles and the global financial crisis of 2008. Methodology. In order to analyse the data, the correlation between variables was measured. The volatility of macroeconomic indicators was gauged using the standard deviation. Based on panel regressions with fixed effects, models were created to demonstrate the influence of macroeconomic stability on economic growth in 15 countries across Central and Eastern Europe over a 30-year period (1991-2021). Results. The analysis using panel regressions with fixed effects shows a significant impact of macroeconomic stability indicators on economic growth after the 2008 global financial crisis, compared to a very small impact during the 2000-2008 boom. The growth of indicators of the real effective exchange rate and total official reserves have a positive impact on economic growth during the boom, while the impact of these indicators decreases significantly in the post-crisis period, and the impact of the lending rate, the current account balance and the unemployment rate increases. It should be noted that the dominant positive factor influencing economic growth in all periods is the budget balance and the weak influence of the exchange rate. Practical implications. The author identifies certain combinations of macroeconomic indicators to create a successful macroeconomic policy for sustainable economic growth in Central and Eastern Europe. Value / Оriginality. The paper assesses and analyses the relationship between macroeconomic stability and economic growth in Central and Eastern European countries during both recession and boom periods, as well as in the post-crisis downturn after 2008, in order to achieve stable welfare, confidence in the future for the whole society and the success of long-term investment projects
Molecular genetic characteristics of gastric cancers from the surgeon’s point of view
No full textDubinina V. G., Mashukov A. A., Lukyanchuk O. V., Bilenko A. A., Zgura A. N., Raciborsky D. V., Lee S. N. Molecular genetic characteristics of gastric cancers from the surgeon’s point of view. Journal of Education, Health and Sport. 2016;6(11):592-621. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.200394
http://ojs.ukw.edu.pl/index.php/johs/article/view/4063
The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23.12.2015).
755 Journal of Education, Health and Sport eISSN 2391-8306 7
© The Author (s) 2016;
This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,
provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License
(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.
This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial
use, distribution and reproduction in any medium, provided the work is properly cited.
The authors declare that there is no conflict of interests regarding the publication of this paper.
Received: 02.11.2016. Revised 22.11.2016. Accepted: 30.11.2016.
MOLECULAR GENETIC CHARACTERISTICS OF GASTRIC CANCERS FROM THE SURGEON’S POINT OF VIEW
V. G. Dubinina1, A. A. Mashukov2, O. V. Lukyanchuk2, A. A. Bilenko1, A. N. Zgura2,
D. V. Raciborsky2, S. N. Lee2
1Odessa National Medical university
2Odessa Regional Oncology center
Summary
A study on the expression of oncoproteins in stomach` carcinomas, has been turned into a real research basically due to the abundance of results and their comprehensive interpretations. The study carried out on the abdominal onco-surgical department of Odessa Regional Oncology Center, included a study of 188 patients operated on for gastric cancer (GC) between 2007-2011. In all cases was performed the so-called lymphadenectomy for the principal reason of extensive preventive biopsy of visually unchanged lymph nodes. We spend a multivariate analysis of interactions between the expression of oncoproteins p53, VEGFR-3, erbB2, Ki67 and micro involvement of tumor vasculature (ly, v), the local growth (T), the presence of residual tumor tissue (the R), the degree of tumor differentiation (the G) the degree of regional lymph nodes involvement (N) and type of infiltration (Inf α, β, Inf Υ).
Keywords: Stomach cancer, Immunohistochemistry and Oncoproteins
Combined Optical And Electrical Analysis of AlGaN-Based Deep-UV LEDs Reliability
No full textThis paper describes an analysis of the reliability of AlGaN-based
deep-UV Light-Emitting Diodes (LEDs) emitting in the range 280-
340 nm. LEDs have been aged at their nominal operating current,
and during treatment their electrical and optical characteristics have
been continuously monitored.
Measurement results show that (i) constant current stress can
induce degradation of the optical power emitted by the devices; (ii)
degradation is more prominent at low measuring current level, thus
suggesting that efficiency decrease is related to the generation of
non-radiative paths; (iii) degradation does not imply a significant
variation of the operating voltage of the devices, thus indicating that
the characteristics of the ohmic contacts are stable over stress time;
(iv) optical power decrease takes place together with modifications of
the C-V apparent charge profiles, indicating that the generation of
non-radiative paths is related to charge instabilities in the QW region
Evaluation advanced lymph node dissection impact on long-term survival rate of gastric cancer patients
No full textDubinina V. G., Mashukov A. A., Zgura A. N., Bilenko A. A., Merlich S. V., Raziborsky D. V., Shilin I. V. Evaluation advanced lymph node dissection impact on long-term survival rate of gastric cancer patients. Journal of Education, Health and Sport. 2015;5(4):52-71. ISSN 2391-8306. DOI: 10.5281/zenodo.16594
http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%284%29%3A52-71
https://pbn.nauka.gov.pl/works/553136
http://dx.doi.org/10.5281/zenodo.16594
Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011 – 2014 http://journal.rsw.edu.pl/index.php/JHS/issue/archive
Deklaracja.
Specyfika i zawartość merytoryczna czasopisma nie ulega zmianie.
Zgodnie z informacją MNiSW z dnia 2 czerwca 2014 r., że w roku 2014 nie będzie przeprowadzana ocena czasopism naukowych; czasopismo o zmienionym tytule otrzymuje tyle samo punktów co na wykazie czasopism naukowych z dnia 31 grudnia 2014 r.
The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1089. (31.12.2014).
© The Author (s) 2015;
This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland and Radom University in Radom, Poland
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,
provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License
(http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.
This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial
use, distribution and reproduction in any medium, provided the work is properly cited.
The authors declare that there is no conflict of interests regarding the publication of this paper.
Received: 20.01.2014. Revised 27.02.2015. Accepted: 15.03.2015.
Evaluation advanced lymph node dissection impact on long-term survival rate of gastric cancer patients
V. G. Dubinina1, A. A. Mashukov1, A. N. Zgura2, A. A. Bilenko1, S. V.Merlich2, D. V. Raziborsky2, I. V.Shilin2
Odessa National Medical University1, Odessa, Ukraine
Odessa Regional Oncological Dispansery2, Odessa, Ukraine
Abstract
Over a period of 2007-2011 188 stomach cancer (SC) patients have been included in the research in abdominal oncosurgical department of Odessa regional oncological dispensary. It was retrospective, one-center, nonrandomized research. Volume of lymph node dissections differed by quantity of lymph nodes to be removed. All patients were divided into three groups. Patients with D1 or D1+ lymph node dissections have been performed, totally 90 patients are included in group of historical control. The main group includes 33 patients to whom D3 lymph node dissections is executed and, finally, control group – 65 patients dissected up to the D2 volume. In all cases so-called lymph node dissections for principal reasons have been executed. The multifactorial analysis of patients survival is implemented depending on a type of a lymph node dissections, a stage of the cancer, number of involved lymph nodes, involvement of the tumoral microcirculatory net (ly is carried out, v) signs of a perinevral invasion (Nev), availability of residual tumoral tissue (R), degree of a differentiation (G). Regardless of a disease stage, SC at 60% of patients, represented with initially hematologicaly disseminated disease. 40% of SC`s had no signs of intratumoral microcirculatory net involvement even in case of more than 15 regional lymph nodes are involved. In the absence of a SC perinevral invasion appeared to be the most precise predictive marker. The conclusion is made some brand new additional prognostic factors could play a crucial role in more accurate patients selection for expanded lymph node dissections.
Keywords: stomach cancer, extended lymph node dissections
Some novel ways of gastric cancer patients treatment personification
No full textKirkilevsky S. I., Lurín A. G., Dubinina V. G., Lukyanchuk O. V., Mashukov A. A., Bilenko A. A., Zgura A. N., Osadchy D. N., Maksimovskiy V. E. Some novel ways of gastric cancer patients treatment personification. Journal of Education, Health and Sport. 2017;7(5):516-538. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.801825
http://ojs.ukw.edu.pl/index.php/johs/article/view/4499
The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26.01.2017).
1223 Journal of Education, Health and Sport eISSN 2391-8306 7
© The Author (s) 2017;
This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,
provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License
(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.
This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial
use, distribution and reproduction in any medium, provided the work is properly cited.
The authors declare that there is no conflict of interests regarding the publication of this paper.
Received: 05.05.2017. Revised: 23.05.2017. Accepted: 31.05.2017.
UDK 616.33-006.6-089-085.277.3
SOME NOVEL WAYS OF GASTRIC CANCER PATIENTS TREATMENT PERSONIFICATION
S. I. Kirkilevsky1, A. G. Lurín3, V. G. Dubinina2, O. V. Lukyanchuk2,3,
A. A. Mashukov1,2,3, A. A. Bilenko2, A. N. Zgura3, D. N. Osadchy2, V. E. Maksimovskiy2
National Cancer Institute1, Kiev
Odessa National Medical university2, Odessa
Odessa Regional Oncology Center3, Odessa
Abstract
In this paper the authors perform the analysis of molecular and morphological factors influencing the survival of patients with gastric cancer (n = 221). They analyzed the survival rate in this group of patients based on the analysis of molecular markers VEGFR, p53, Her2, Ki-67. Measured role in the survival such factors as the degree of differentiation of primary gastric tumors, the presence of microscopic tumor involvement of perineural and perivascular spaces, the degree of invasion to gastric wall by T1 = 1 and to T4a = 4, T4b = 5, number of regional lymph nodes affected by metastasis, and other factors. As an arbitrator used survival curves calculated by the method of R. J. Cox, time of lifespan, measured in months, as well as a comparison of the areas under the curves of survival.
Keywords: gastric cancer (GC), lymph node dissection, multiorgan resection, immunohistochemistry, genetic classification
Hermeneutics in the Context of Scientist Ignorance
No full textЗ’ясовано залежність герменевтичного процесу від талант у, ерудиції та сумлінності перекладача, від його здатності ефективно діяти в обставинах культурного незнання, про що Микола Кузанський твердив: «Знання є незнання». Осягнення культурного незнання автора й реципієнта невіддільне від хронотопу.It was found hermeneutical process dependent on talent, erudition and integrity of interpreter on its ability to operate effectively in situations of cultural ignorance of Nicholas of Cusa argued that “knowledge is ignorance”. Comprehension of cultural ignorance of the author and recipient inseparable from the time-spac
Hermeneutics in the Context of Scientist Ignorance
No full textЗ’ясовано залежність герменевтичного процесу від талант у, ерудиції та сумлінності перекладача, від його здатності ефективно діяти в обставинах культурного незнання, про що Микола Кузанський твердив: «Знання є незнання». Осягнення культурного незнання автора й реципієнта невіддільне від хронотопу.It was found hermeneutical process dependent on talent, erudition and integrity of interpreter on its ability to operate effectively in situations of cultural ignorance of Nicholas of Cusa argued that “knowledge is ignorance”. Comprehension of cultural ignorance of the author and recipient inseparable from the time-spac
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