765 research outputs found

    Supplementary_Data - The Binding of BF-227-Like Benzoxazoles to Human α-Synuclein and Amyloid β Peptide Fibrils

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    Supplementary_Data for The Binding of BF-227-Like Benzoxazoles to Human α-Synuclein and Amyloid β Peptide Fibrils by Lee Josephson, Nancy Stratman, YuTing Liu, Fang Qian, Steven H. Liang, Neil Vasdev, and Shil Patel in Molecular Imaging</p

    Xian xing jin na mi bang san jiao zhen lie zhong de ci deng li zi ti

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    Tao, Yuting = 綫性金納米棒三角陣列中的磁等離子體 / 陶煜庭.Thesis M.Phil. Chinese University of Hong Kong 2015.Includes bibliographical references.Abstracts also in Chinese.Title from PDF title page (viewed on 14, November, 2016).Tao, Yuting = Xian xing jin na mi bang san jiao zhen lie zhong de ci deng li zi ti / Tao Yuting

    Magnetic wallpaper Dirac fermions and topological magnetic Dirac insulators

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    Topological crystalline insulators (TCIs) can host anomalous surface states which inherits the characteristics of crystalline symmetry that protects the bulk topology. Especially, the diversity of magnetic crystalline symmetries indicates the potential for novel magnetic TCIs with distinct surface characteristics. Here, we propose a topological magnetic Dirac insulator (TMDI), whose two-dimensional surface hosts fourfold-degenerate Dirac fermions protected by either the pc4mmp'_c4mm or p4gmp4'g'm magnetic wallpaper group. The bulk topology of TMDIs is protected by diagonal mirror symmetries, which give chiral dispersion of surface Dirac fermions and mirror-protected hinge modes. We propose candidate materials for TMDIs including Nd4_4Te8_8Cl4_4O20_{20} and DyB4_4 based on first-principles calculations, and construct a general scheme for searching TMDIs using the space group of paramagnetic parent states. Our theoretical discovery of TMDIs will facilitate future research on magnetic TCIs and illustrate a distinct way to achieve anomalous surface states in magnetic crystals.Comment: 10+36 pages, 4+23 figures, published versio

    Deep Bayesian survival analysis of rail useful lifetime

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    Reliable estimation of rail useful lifetime can provide valuable information for predictive maintenance in railway systems. However, in most cases, lifetime data is incomplete because not all pieces of rail experience failure by the end of the study horizon, a problem known as censoring. Ignoring or otherwise mistreating the censored cases might lead to false conclusions. Survival approach is particularly designed to handle censored data for analysing the expected duration of time until one event occurs, which is rail failure in this paper. This paper proposes a deep Bayesian survival approach named BNN-Surv to properly handle censored data for rail useful lifetime modelling. The proposed BNN-Surv model applies the deep neural network in the survival approach to capture the non-linear relationship between covariates and rail useful lifetime. To consider and quantify uncertainty in the model, Monte Carlo dropout, regarded as the approximate Bayesian inference, is incorporated into the deep neural network to provide the confidence interval of the estimated lifetime. The proposed approach is implemented on a four-year dataset including track geometry monitoring data, track characteristics data, various types of defect data, and maintenance and replacement (M&amp;R) data collected from a section of railway tracks in Australia. Through extensive evaluation, including Concordance index (C-index) and root mean square error (RMSE) for evaluating model performance, as well as a proposed CW-index for evaluating uncertainty estimations, the effectiveness of the proposed approach is confirmed. The results show that, compared with other commonly used models, the proposed approach can achieve the best concordance index (C-index) of 0.80, and the estimated rail useful lifetimes are closer to real lifetimes. In addition, the proposed approach can provide the confidence interval of the estimated lifetime, with a correct coverage of 81% of the actual lifetime when the confidence interval is 1.38, which is more useful than point estimates in decision-making and maintenance planning of railroad systems.Railway Engineerin

    Quality failures in Energy-saving renovation projects in Northern China

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    The energy-saving renovation of an existing building is a critical strategy in achieving a longterm energy goal in the Chinese context. However, in China, building energy renovation projects are subjected to quality failures resulting in energy wastage, a decrease in the energy efficiency of the project, an increase in project cost, and thus negatively affecting the overall performance of the renovation projects. In order to avoid them happening in the future, it is essential to find and analyse the causes of quality failures in energy-saving renovation projects. Therefore, using a four-step process, this research aims to deepen the understanding of the causes of quality failures in energy-saving renovation projects of the existing residential buildings. The first and second steps are to identify and analyse the quality failures and their causes. The deeper insights from a quality management perspective are explored in the third step. The fourth step is to investigate how the actors and their interactions affect and cause quality failures during the renovation policy implementation process. This research mainly concludes the causes of quality failures in the building energy renovation projects. It is important to state that most of the quality failures can be avoided at the management level. Some external causes originated at a policy level and outside the project. The findings of this research would be valuable for policy-makers and project coordinators both for predicting and avoiding quality failures and for developing proper action and policy interventions to ensure successful building energy renovations in the future.Housing Quality and Process Innovatio

    Strategic leadership in the face of sociopolitical and sociocultural challenges

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    Firms are living through a period of unprecedented sociopolitical and sociocultural changes. The shifts in external and internal environments increasingly require firms to strategically navigate social challenges not only in their wider societal context, such as cultural conflicts, climate change, and polarization but also within the organizations, including increasing representation diversity within their own boundaries. However, we still lack an integrated understanding of the roles of corporate executives as strategic leaders in navigating such complexity in the environment. In this symposium, we bring together four papers focusing on the different roles of corporate executives (CEOs, CHROs, and TMTs as a whole) in addressing external sociopolitical challenges (e.g., controversial societal issues and activist campaigns) and internal sociocultural complexity (e.g., human resources and national diversity). Do Authentic Activist CEOs Gain Favor from Shareholder Activists? Author: Yuting Yang; Iowa State University CEO Exposure to Diverse Demands from Shareholder Activists and Firm Responses to Subsequent Activism Author: Canquan (Charles) Li; The Hong Kong Polytechnic University Author: Shuping Li; The Hong Kong Polytechnic University Understanding Chief Human Resource Officer Tenures and Activities on Top Management Teams Author: Andrew Millin; Florida International University Author: Donald Joseph Schepker; University of South Carolina The Contrasting Implications of TMT Surface- and Deep-Level National Diversity for Firm Performance Author: Aaron Aujla; London School of Economics and Political Scienc
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