1,720,957 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
The effect of postbiotics on in vitro model of inflammatory bowel disease
No full textFermentirani čaj kombucha se konzumira tisućama godina i prepisuju mu se mnoga ljekovita
svojstva. Dosad je dokazano kako ima značajan antioksidacijski učinak i potencijalno pozitivno
djelovanje na mnoge bolesti od kojih su neke i upalne bolesti crijeva. S obzirom da za upalne
bolesti crijeva ne postoji terapija koja dovodi do izlječenja, istražuju se novi faktori uključeni u
patologiju bolesti kao što je oksidacijski stres i očuvanje epitelne barijere probavnog sustava.
Ovaj diplomski rad istražuje učinak postbiotika kombuche na ljudskom staničnom modelu kokulture staničnih linija Caco-2 i THP-1. Uspostavila sam model zdrave epitelne membrane i
model epitelne membrane u stanju upale te ih tretirala postbiotikom kombuche u različitim
testnim skupinama koje ispituju preventivni i terapijski učinak kombuche. Mjerenjem
transepitelnog otpora sam pokazala da kombucha jača integritet epitelne membrane crijeva.
Mjerenjem razine reaktivnih vrsta kisika nisam pokazala statistički značajan učinak na povećanje
niti smanjenje oksidacijskog stresa. Međutim, analizom ekspresije gena za enzime oksidacijskog
stresa pokazala sam da ih stanje upale blago pojačava i da tretman samo kombuchom izrazito
povećava ekspresiju katalaze (CAT) i superoksidne dismutaze 1 (SOD1). Rezultati istraživanja
upućuju na potencijalno bolji integritet crijevne barijere i veću spremnost obrane od
oksidacijskog stresa pri konzumaciji fermentiranog čaja kombuche.Fermented kombucha tea has been consumed for thousands of years and is thought to have
healing properties. It has been confirmed to have a significant antioxidative effect and potentially
positive effect on many diseases, among which is Inflammatory bowel disease (IBD). Current
IBD therapies do not offer a complete cure for the disease, so new targets such as oxidative stress
and gut-barrier disruption are being investigated. This master thesis focuses on the effect of
kombucha postbiotics on a human cell co-culture model using Caco-2 and THP-1 cell lines. I
established a healthy co-culture and an inflamed one and I treated them both with the postbiotic
in different test groups which investigate kombucha’s preventative and therapeutic potential. By
measuring the transepithelial electrical resistance (TEER), I showed that the postbiotic has an
influence on improving barrier integrity. Measurements of reactive oxygen species did not show
statistically significant decrease nor increase in oxidative stress. But gene expression analysis of
antioxidant enzymes showed that inflammation causes a slight increase in their expression and
that treatment with kombucha alone, causes a drastic increase in expression of catalase (CAT)
and superoxide dismutase 1 (SOD1). Overall, the findings suggest that consuming fermented
kombucha tea may improve the gut barrier integrity and enhance the body's defense against
oxidative stress
The effect of postbiotics on in vitro model of inflammatory bowel disease
No full textFermentirani čaj kombucha se konzumira tisućama godina i prepisuju mu se mnoga ljekovita
svojstva. Dosad je dokazano kako ima značajan antioksidacijski učinak i potencijalno pozitivno
djelovanje na mnoge bolesti od kojih su neke i upalne bolesti crijeva. S obzirom da za upalne
bolesti crijeva ne postoji terapija koja dovodi do izlječenja, istražuju se novi faktori uključeni u
patologiju bolesti kao što je oksidacijski stres i očuvanje epitelne barijere probavnog sustava.
Ovaj diplomski rad istražuje učinak postbiotika kombuche na ljudskom staničnom modelu kokulture staničnih linija Caco-2 i THP-1. Uspostavila sam model zdrave epitelne membrane i
model epitelne membrane u stanju upale te ih tretirala postbiotikom kombuche u različitim
testnim skupinama koje ispituju preventivni i terapijski učinak kombuche. Mjerenjem
transepitelnog otpora sam pokazala da kombucha jača integritet epitelne membrane crijeva.
Mjerenjem razine reaktivnih vrsta kisika nisam pokazala statistički značajan učinak na povećanje
niti smanjenje oksidacijskog stresa. Međutim, analizom ekspresije gena za enzime oksidacijskog
stresa pokazala sam da ih stanje upale blago pojačava i da tretman samo kombuchom izrazito
povećava ekspresiju katalaze (CAT) i superoksidne dismutaze 1 (SOD1). Rezultati istraživanja
upućuju na potencijalno bolji integritet crijevne barijere i veću spremnost obrane od
oksidacijskog stresa pri konzumaciji fermentiranog čaja kombuche.Fermented kombucha tea has been consumed for thousands of years and is thought to have
healing properties. It has been confirmed to have a significant antioxidative effect and potentially
positive effect on many diseases, among which is Inflammatory bowel disease (IBD). Current
IBD therapies do not offer a complete cure for the disease, so new targets such as oxidative stress
and gut-barrier disruption are being investigated. This master thesis focuses on the effect of
kombucha postbiotics on a human cell co-culture model using Caco-2 and THP-1 cell lines. I
established a healthy co-culture and an inflamed one and I treated them both with the postbiotic
in different test groups which investigate kombucha’s preventative and therapeutic potential. By
measuring the transepithelial electrical resistance (TEER), I showed that the postbiotic has an
influence on improving barrier integrity. Measurements of reactive oxygen species did not show
statistically significant decrease nor increase in oxidative stress. But gene expression analysis of
antioxidant enzymes showed that inflammation causes a slight increase in their expression and
that treatment with kombucha alone, causes a drastic increase in expression of catalase (CAT)
and superoxide dismutase 1 (SOD1). Overall, the findings suggest that consuming fermented
kombucha tea may improve the gut barrier integrity and enhance the body's defense against
oxidative stress
The effect of postbiotics on in vitro model of inflammatory bowel disease
No full textFermentirani čaj kombucha se konzumira tisućama godina i prepisuju mu se mnoga ljekovita
svojstva. Dosad je dokazano kako ima značajan antioksidacijski učinak i potencijalno pozitivno
djelovanje na mnoge bolesti od kojih su neke i upalne bolesti crijeva. S obzirom da za upalne
bolesti crijeva ne postoji terapija koja dovodi do izlječenja, istražuju se novi faktori uključeni u
patologiju bolesti kao što je oksidacijski stres i očuvanje epitelne barijere probavnog sustava.
Ovaj diplomski rad istražuje učinak postbiotika kombuche na ljudskom staničnom modelu kokulture staničnih linija Caco-2 i THP-1. Uspostavila sam model zdrave epitelne membrane i
model epitelne membrane u stanju upale te ih tretirala postbiotikom kombuche u različitim
testnim skupinama koje ispituju preventivni i terapijski učinak kombuche. Mjerenjem
transepitelnog otpora sam pokazala da kombucha jača integritet epitelne membrane crijeva.
Mjerenjem razine reaktivnih vrsta kisika nisam pokazala statistički značajan učinak na povećanje
niti smanjenje oksidacijskog stresa. Međutim, analizom ekspresije gena za enzime oksidacijskog
stresa pokazala sam da ih stanje upale blago pojačava i da tretman samo kombuchom izrazito
povećava ekspresiju katalaze (CAT) i superoksidne dismutaze 1 (SOD1). Rezultati istraživanja
upućuju na potencijalno bolji integritet crijevne barijere i veću spremnost obrane od
oksidacijskog stresa pri konzumaciji fermentiranog čaja kombuche.Fermented kombucha tea has been consumed for thousands of years and is thought to have
healing properties. It has been confirmed to have a significant antioxidative effect and potentially
positive effect on many diseases, among which is Inflammatory bowel disease (IBD). Current
IBD therapies do not offer a complete cure for the disease, so new targets such as oxidative stress
and gut-barrier disruption are being investigated. This master thesis focuses on the effect of
kombucha postbiotics on a human cell co-culture model using Caco-2 and THP-1 cell lines. I
established a healthy co-culture and an inflamed one and I treated them both with the postbiotic
in different test groups which investigate kombucha’s preventative and therapeutic potential. By
measuring the transepithelial electrical resistance (TEER), I showed that the postbiotic has an
influence on improving barrier integrity. Measurements of reactive oxygen species did not show
statistically significant decrease nor increase in oxidative stress. But gene expression analysis of
antioxidant enzymes showed that inflammation causes a slight increase in their expression and
that treatment with kombucha alone, causes a drastic increase in expression of catalase (CAT)
and superoxide dismutase 1 (SOD1). Overall, the findings suggest that consuming fermented
kombucha tea may improve the gut barrier integrity and enhance the body's defense against
oxidative stress
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