305,197 research outputs found
Self tanning.
No full textDihydroxyacetone (DHA), binding the amino terminal of epidermal proteins, imparts an orange-brown colour to the skin 3-10 h from the application. The degree of skin darkening is related to the DHA concentration, usually from 2.5 to 6.5%. The action mechanism of DHA involves the formation of so-called melanoids, chromophores generated in the upper layers of the stratum corneum. Besides the browning effect, useful for cosmetic purposes or for masking hypopigmented macules of vitiligo, DHA application protects the skin against long-wave ultraviolet (λ>320 nm) showing an UVA protection factor from 1.7 to 2.2, depending on its concentration. The DHA does not protect against UVB (λ<320 nm). DHA containing sunscreens are useful to prevent polymorphous light eruptions or erythropoietic protoporphyria and to give a tanned look to hair-skinned individuals avoiding harmful sun exposures
La casa attrezzata
No full textIl libro focalizza i diversi possibili tipi di integrazione fra architettura e arredo attraverso l’analisi sistematica di abitazioni esemplari, progettate o realizzate dagli anni venti del Novecento ad oggi. Fra i poli opposti dell’involucro strutturale completamente attrezzato e il contenitore vuoto e indifferente alle necessità di chi abita, la grande varietà delle soluzioni indagate suggerisce il superamento della attuale frattura nella cultura del progetto fra edilizia e arredo, e di stereotipi produttivi fin troppo consolidati
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
A case of chronic actinic dermatitis treated with topical tacrolimus
No full textIntroduction: The treatment of chronic actinic dermatitis (CAD), a sun-induced disorder characterized by a persistent eczematous eruption, involves photoprotective measures, topical corticosteroid therapy and, in more severe cases, systemic immunosuppression. The potential side effects of systemic immunosuppressant drugs prompted us to evaluate the efficacy of topical tacrolimus for treatment of CAD. Patient and treatment: A 58-year-old man with CAD, resistant to previous treatment with topical and systemic corticosteroids, oral cyclosporine and PUVA-photochemotherapy, was treated with tacrolimus ointment 0.1% once a day. Results: Tacrolimus ointment led to significant improvement of pruritus and severe eczematous skin lesions after 20 days of treatment. Conclusions: Tacrolimus shows a beneficial effect on CAD; this could be attributed to the fact that CAD is characterized by a lymphohistiocytic infiltrate producing a chronic eczema and that tacrolimus blocks the activation of lymphocytes and other immune system cells, also inhibiting the release of mediators from cutaneous mast cells and basophils
LONG-LASTING PIGMENTATION MORE THAN ITS INTENSITY IS A RELIABLE INDICATOR OF SKIN SUN RESISTANCE
No full textDispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Controllo motorio E disartria nella malattia di Parkinson: uno studio pilota sulla labializzazione
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