19,821 research outputs found
Uso y abuso de opioides en el tratamiento del dolor crónico
No full textCopa Prieto, Ana; director de proyecto: Galán Vázquez, Amalia2022-2023Grado en FarmaciaFacultad de Ciencias de la Salu
Positive hits from the SGA screening
No full textdataset posted on 2025-04-01, 19:51 authored by Ana Amiama-Roig, Marta Barrientos-Moreno, Esther Cruz-Zambrano, Luz M. López-Ruiz, Román González-Prieto, Gabriel Ríos-Orelogio, Félix Prado
The name of the positive hits, their PCR validation and the effect of the null mutant on RFA1-MN viability are indicatedPeer reviewe
Raw data for figure panels
No full textfigure posted on 2025-04-01, 19:51 authored by Ana Amiama-Roig, Marta Barrientos-Moreno, Esther Cruz-Zambrano, Luz M. López-Ruiz, Román González-Prieto, Gabriel Ríos-Orelogio, Félix Prado
Original blots for the indicated figure panels are shown.Peer reviewe
Saccharomyces cerevisiae genes studied in the SGA screening
No full textdataset posted on 2025-04-01, 19:51 authored by Ana Amiama-Roig, Marta Barrientos-Moreno, Esther Cruz-Zambrano, Luz M. López-Ruiz, Román González-Prieto, Gabriel Ríos-Orelogio, Félix Prado
Genes analyzed in the customized library of null mutants are shown.Peer reviewe
La Formación Profesional Dual en España: evolución, retos y perspectivas de futuro
No full textPrieto Pérez, Ana María; director de proyecto: Rodríguez Simón, Alejandro Ignacio2024-2025Máster Universitario en Profesorado de Educación Secundaria Obligatoria y Bachillerato, Formación Profesional y Enseñanza de IdiomasFacultad de Ciencias de la Educació
Differential stability of 2'F-ANA*RNA and ANA*RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibility
No full text14 pags., 7 figs., 3 tabs.Hybrids of RNA with arabinonucleic acids 2′F-ANA and ANA have very similar structures but strikingly different thermal stabilities. We now present a thorough study combining NMR and other biophysical methods together with state-of-the-art theoretical calculations on a fully modified 10-mer hybrid duplex. Comparison between the solution structure of 2′F-ANA•RNA and ANA•RNA hybrids indicates that the increased binding affinity of 2′F-ANA is related to several subtle differences, most importantly a favorable pseudohydrogen bond (2′F-purine H8) which contrasts with unfavorable 2′-OH-nucleobase steric interactions in the case of ANA. While both 2′F-ANA and ANA strands maintained conformations in the southern/eastern sugar pucker range, the 2′F-ANA strand's structure was more compatible with the A-like structure of a hybrid duplex. No dramatic differences are found in terms of relative hydration for the two hybrids, but the ANA•RNA duplex showed lower uptake of counterions than its 2′F-ANA•RNA counterpart. Finally, while the two hybrid duplexes are of similar rigidities, 2′F-ANA single strands may be more suitably preorganized for duplex formation. Thus the dramatically increased stability of 2′F-ANA•RNA and ANA•RNA duplexes is caused by differencesin at least four areas, of which structure and pseudohydrogen bonding are the most important. © The Author(s) 2010. Published by Oxford University Press.Spanish Ministerio de Ciencia e Innovacion (grants
CTQ2007-68014-C02-02 to CG and BIO2009-10964 to
MO); Fundacion Marcelino Botin (grant to MO);
Canadian Institutes for Health Research (grant to
M.J.D.); Natural Sciences and Engineering Research
Council of Canada (postgraduate scholarship to
J.K.W.). Funding for open access charge: Canadian
Institutes for Health Research
Prevalencia de Campylobacter spp. en población adulta del Hospital Rawson de Córdoba
No full text1 p.Fil: Prieto Carla Soledad. Hospital Rawson. Infectología; ArgentinaFil; López, Ana Claudia. Hospital Rawson. Infectología; ArgentinaFil: Paván, Javier. Hospital Rawson. Infectología; ArgentinaFil: Littvik, Ana. Hospital Rawson. Infectología; ArgentinaThe Campilobacter genus, wich has been identified as a cause of gastrointestinal infections since the 70´s, is considered now as the main cause of bacterial diarrhea in te pediatric population and an important microorganism in risk group.El género Campylobacter, reconocido desde los 70’como productor de infecciones gastrointestinales, ocupa en la actualidad el primer lugar como agente productor de diarreas bacterianas en población pediátrica y un importante microorganismo en grupos de riesgohttp://www.revista2.fcm.unc.edu.ar/jornadas.pdfFil: Prieto Carla Soledad. Hospital Rawson. Infectología; ArgentinaFil; López, Ana Claudia. Hospital Rawson. Infectología; ArgentinaFil: Paván, Javier. Hospital Rawson. Infectología; ArgentinaFil: Littvik, Ana. Hospital Rawson. Infectología; ArgentinaEnfermedades Infecciosa
Cuerpos disidentes en la mira de la Dirección de Inteligencia de la Policía de la Provincia de Buenos Aires (DIPPBA)
No full textFil: Solari Paz, Ana Cecilia. Comisión Provincial por la Memoria.Fil: Prieto Carrasco, Cristián. Comisión Provincial por la Memoria
Additional genetic requirements for RFA1-MN cell viability in the absence and presence of calcium
No full textfigure posted on 2025-04-01, 19:51 authored by Ana Amiama-Roig, Marta Barrientos-Moreno, Esther Cruz-Zambrano, Luz M. López-Ruiz, Román González-Prieto, Gabriel Ríos-Orelogio, Félix Prado
(A–D) Effect of the indicated mutations in the growth of RFA1-MN cells as determined by spotting 10-fold serial dilutions of the same number of mid-log growing cells onto SMM medium without or with the indicated concentrations of CaCl2. The analyses were repeated at least twice with similar results. Mutants scored in the SGA screening are shown in bold.Peer reviewe
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