186,358 research outputs found
Respiratory allergy to nickel. Description of an atipical clinical case
BACKGROUND: Exposure to nickel sulphate, other than contact dermatitis, can potentially cause respiratory symptoms. Although few cases of occupational rhinitis and asthma are reported in literature, a prolonged exposure can determine sensitization and evolution to respiratory symptoms. OBJECTIVES: Clinical evaluation of a case of occupational rhinitis and asthma due to nickel sulphate. METHODS: A female worker, aged 43 years, has been occupationally exposed to nickel for 22 years. After 1 year she experienced asthma, apparently not work related. She treated the respiratory symptoms for many years, but a slow and progressive increase of the disease was observed. During the last five years a straight relationship between work and symptoms was observed. On-off test was positive. The diagnosis of occupational respiratory disease was based on the work-related symptoms and the specific nasal challenge test result. RESULTS: An early response was observed with nasal symptoms (score 4), increase of anterior nasal airflow resistance (33%), severe dyspnea, haematic eosinophilia, and fall in FEV-1 of 18%. CONCLUSIONS: The prolonged exposure to nickel determined impairment of respiratory function. Nasal challenge, more safe and useful than bronchial challenge, can be considered gold standard for the diagnosis of occupational rhinitis and asthma due to occupational allergens
Reazioni avverse a farmaci e lattice in odontostomatologia: percorso clinico anamnestico.
Detection and clustering of light charged particles via system identification techniques
Fault detection and isolation scheme in continuous time nonlinear stochastic dynamical systems
In this paper, the design of a fault detectiou and isolation scheme is
addressed. We work on plants modelled via continuous-time nonlinear uncertain
systems, where the un(;ertainty and the fault f\mction are assumed to be random
processes. A model-based analytical redundancy apt)roach, which checks on-line
the statistical characteristics of a residual through hypotheses tests, is proposed.
Also a simulation example is discussed, with promising results
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