187,177 research outputs found
Are You Being Rejected or Excluded? Insights from Neuroimaging Studies Using Different Rejection Paradigms
No full textRejection sensitivity is the heightened tendency to perceive or anxiously expect disengagement from others during social interaction. There has been a recent wave of neuroimaging studies of rejection. The aim of the current review was to determine key brain regions involved in social rejection by selectively reviewing neuroimaging studies that employed one of three paradigms of social rejection, namely social exclusion during a ball-tossing game, evaluating feedback about preference from peers and viewing scenes depicting rejection during social interaction. A cross the different paradigms of social rejection, there was concordance in regions for experiencing rejection, namely dorsal anterior cingulate cortex (ACC), subgenual ACC and ventral ACC. Functional dissociation between the regions for experiencing rejection and those for emotion regulation, namely medial prefrontal cortex, ventrolateral prefrontal cortex (VLPFC) and ventral striatum, was evident in the positive association between social distress and regions for experiencing rejection and the inverse association between social distress and the emotion regulation regions. The paradigms of social exclusion and scenes depicting rejection in social interaction were more adept at evoking rejection-specific neural responses. These responses were varyingly influenced by the amount of social distress during the task, social support received, self-esteem and social competence. Presenting rejection cues as scenes of people in social interaction showed high rejection sensitive or schizotypal individuals to under-activate the dorsal ACC and VLPFC, suggesting that such individuals who perceive rejection cues in others down-regulate their response to the perceived rejection by distancing themselves from the scene
Data for: Neural responses to criticism and praise vary with schizotypy and perceived emotional support
No full textWill provide details late
Data for: Perceived criticism and perceived praise predict schizotypy in the non-clinical population: the role of affect and perceived expressed emotion
No full textPlease see the attache file
Symplocos sisparensis B. Karthik, Murug., Anusuba, Premkumar & R. Tharani 2023, sp. nov.
No full text<i>Symplocos sisparensis</i> B. Karthik, Murug., Anusuba, Premkumar & R. Tharani, <i>sp. nov.</i> (Figure 1) <p> <b>Type:—</b> INDIA. Tamil Nadu: The Nilgiris Distr., Way to Nadugani-Mukurthi National Park, 11°15′13.94″ N, 76°29′13.50″ E, ± 2223 m, 29.11.2022, <i>M</i> <i>. Murugesan & B.</i> <i>Karthik 148115</i> (Holotype MH; Isotypes MH).</p> <p> <b>Diagnosis:—</b> Small tree with glabrous branches (vs medium to large tree with villous branches); leaf margins crenulate, each crenulate tooth with a blunt tip, glabrous abaxially with 4–6 pairs of lateral veins (vs leaf margins serrulate, each serrulate tooth with sharp tip, midrib sparsely long-hairy with 7–13 pairs of lateral veins); calyx lobes equal, glabrous and pinkish along margins, hairy in middle of abaxial side (vs calyx lobes unequal, glabrous or sparsely appressed-hairy, greenish along margins); style hairy, curved and constricted at middle (vs style glabrous except at base, style curved without constriction); fruits 7–10 mm long, globose or cylindrical to ellipsoid with blunt apex (vs fruits 1.2–1.4 cm long, broadly cylindrical to ellipsoid or oblongoid, truncate at ends) (Figure 3).</p> Description <p>Large shrub to small tree, up to 4 m high. Bark grey, young branchlets light greenish yellow, glabrous, covered with pulvinate leaf scars, twigs have discontinuous growth. Leaves simple, alternate-spiral, exstipulate; lamina 5–9 × 2–3.5 cm, elliptic, shortly attenuate towards base, crenulate along margin, acute-acuminate at apex, mid vein prominent abaxially, impressed adaxially, secondary veins abaxially prominent, lateral veins 4–6-pair, convergent towards apex with intramarginal venation, terminal vegetative juvenile leaves abaxially pubescent also covered by bract-like scales, densely pubescent abaxially. Petioles 1–1.5 cm long, brown, canaliculate near the base on adaxial side, glabrous. Inflorescence in axillary spikes on young and rarely on mature branches; sometimes flowers subsessile. Peduncles 1–5 cm long, pubescent at flowering, glabrescent during fruiting. Bracts 3.5–4.5 × 2.5–3 mm, ovate to cymbiform. Bracteoles ovate-lanceolate, 1–2 × 1–1.5 mm, caducous, brown, acute at apex, truncate at base, ciliate along margin, concave, appressed sericeous adaxially, glabrous abaxially. Flowers 3–9 in cluster on a spike, 6–7.5 × 7–8 mm. Calyx tube green, ca. 2 mm long, glabrous, 5-lobed; lobes deltoid, 1–1.5 × 1–1.5 mm, glabrous and green to pinkish at margins, sparsely hairy from middle to apex abaxially. Corolla white, 3–4.5 × 3–3.5 mm, deeply 5-lobed; lobes connate at base, elliptic, obtuse or subobtuse at apex, 5-veined. Stamens 55–70 in 4 or 5 irregular series, uppermost series extending beyond corolla, 1–6 mm long; filaments equally wide from base to apex; anthers ca. 1 mm long. Style 2–3 mm long, shorter than corolla, constricted at middle; stigma capitate. Disk 5-glandular, stellate-hairy. Fruits 7–10 × 4–6 mm, globose or cylindrical to ellipsoid with blunt apex, not grooved.</p> <p> <b>Flowering & Fruiting:</b> October–December.</p> <p> <b>Etymology:</b> The new species named after the type locality, Sispara Ghats of Mukurthi National Park, The Nilgiris, Tamil Nadu.</p> <p> <b>Habitat & Ecology:</b> <i>Daphniphyllum neilgherrense</i> (Wight) Rosenthal (1919: 7), <i>Eurya nitida</i> Korthals (1841: 115), <i>Hedyotis sisaparensis</i> Gage (1906: 244), <i>Berberis nilghiriensis</i> Ahrendt (1945: 1), <i>Rhodomyrtus tomentosa</i> (Aiton) Hasskarl (1842: 35), <i>Rubus ellipticus</i> Smith (1815: 16) and <i>Myrsine wightiana</i> Wallich ex de Candolle (1834: 106).</p> <p> <b>Distribution:</b> Mukurthi National Park, The Nilgiris District, Tamil Nadu, India (Figure 2).</p> <p> <b>Conservation status:</b> During the present study, the authors have observed seven individuals of this new species, on the way to Nadugani-Mukurthi National Park covering about 2 km 2 geographical areas. Therefore, it is provisionally assessed here as Critically Endangered [CR, D], according to IUCN Red List Categories and Criteria (IUCN 2022).</p>Published as part of <i>Karthik, B., Murugesan, M., Anusuba, V., Premkumar, M. & Tharani, R., 2023, Symplocos sisparensis (Symplocaceae), a new species from the Nilgiri Biosphere Reserve, India, pp. 83-90 in Phytotaxa 589 (1)</i> on pages 84-89, DOI: 10.11646/phytotaxa.589.1.8, <a href="http://zenodo.org/record/7755073">http://zenodo.org/record/7755073</a>
Amantadine inhibits the function of an ion channel encoded by GB virus-B but fails to inhibit virus replication
No full textX. Dong, A. Premkumar, G. Haqshenas, P.W. Gage and E.J. Gowan
Design and development of non-isolated modified SEPIC DC-DC converter topology for high-step-up applications: Investigation and hardware implementation
No full textA new non-isolated modified SEPIC front-end dc-dc converter for the low power system is proposed in this paper, and this converter is the next level of the traditional SEPIC converter with additional devices, such as two diodes and splitting of the output capacitor into two equal parts. The circuit topology proposed in this paper is formulated by combining the boost structure with the traditional SEPIC converter. Therefore, the proposed converter has the benefit of the SEPIC converter, such as continuous input current. The proposed circuit structure also improves the features, such as high voltage gain and high conversion efficiency. The converter comprises one MOSFET switch, one coupled inductor, three diodes, and two capacitors, including the output capacitor. The converter effectively recovers the leakage energy of the coupled inductor through the passive clamp circuit. The operation of the proposed converter is explained in continuous conduction mode (CCM) and discontinuous conduction mode (DCM). The required voltage gain of the converter can be acquired by adjusting the coupled inductor turn’s ratio along with the additional devices at less duty cycle of the switch. The simulation of the proposed converter under CCM is carried out, and an experimental prototype of 100 W, 25 V/200 V is made, and the experimental outcomes are presented to validate the theoretical discussions of the proposed converter. The operating performance of the proposed converter is compared with the converters discussed in the literature. The proposed converter can be extended by connecting voltage multiplier (VM) cell circuits to get the ultra-high voltage gain
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Interfacial catalysis of aldol reactions by prolinamide surfactants in reverse micelles
No full textL-Proline and their derivatives are among the most important class of organic catalysts. Three prolinamide surfactants were designed and synthesized. Although the surfactants carried identical catalytic groups, their headgroups contained different functionalities that affected their ability to self-assemble under reverse micelle conditions and hydrogen-bond with the reactants. The surfactant with a zwitterionic headgroup capable of strong aggregation was found to have the highest activity. The self-association of the surfactants played critical roles in the enhanced activity. The location of the catalytic groups at the surfactant/polar solvent interface also endowed unusual selectivity in the catalyzed aldol reactions.This is a manuscript of an article published as Arivalagan, Premkumar Rathinam, and Yan Zhao. "Interfacial catalysis of aldol reactions by prolinamide surfactants in reverse micelles." Organic & Biomolecular Chemistry 13, no. 3 (2015): 770-775. DOI: 10.1039/C4OB02074J. Posted with permission.</p
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Cytotoxic compounds from the marine actinobacterium Streptomyces corchorusii AUBN(1)/7
No full textWe isolated a bioactive streptomycete from marine sediment samples collected at Bay of Bengal, India, during our systematic study of marine actinobacteria. The taxonomic studies indicated that the isolate is related to Strepomyces corchorusii. However, it differed in certain aspects, and, hence, was designated as S. corchorusii AUBN(1)/7. A solvent extraction followed by a chromatographic purification helped obtain from the isolate two cytotoxic compounds, which were identified as resistomycin, a quinone-related antibiotic, and tetracenomycin D, an anthraquinone antibiotic, on the basis of spectral data of pure compounds. They demonstrated in vitro a potent cytotoxic activity against cell lines HMO2 (gastric adenocarcinoma) and HePG2 (hepatic carcinoma) and also exhibited weak antibacterial activities against Gram-positive and Gram-negative bacteria
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