9 research outputs found
Clinical evaluation of Vrsya effect of Pūga Khanda on sexual health and seminal parameters
No full textBackground: Due to changes in life-style, the human beings are losing their Vr.s.yata- (virility). Bio-medicine hasn′t been able to address this challenge. Hence, we see that many people seek the help of herbal medicines to get relief. In view of the above, it becomes necessary to provide potent formulations to address this ailment.
Objectives: The study was designed to evaluate the efficacy of Pūga Khan.d.a on seminal parameters and sexual health.
Materials and Methods: Pūga Khan.d.a has been mentioned as Vr.s.ya (aphrodisiac) in the 30 th chapter of Bhaiśajyaratnāvali. A simple-randomised, single-blinded, placebo-controlled study comparing this Pūga Khan.d.a preparation with a placebo was conducted in 52 patients attending O.P.D. of Department of Rasa Shastra and Bhaishajya Kalpana of Muniyal Institute of Ayurveda Medical Sciences, Manipal. An elaborative case taking Proforma was specially designed for this purpose incorporating all aspects of the disease in the Ayurvedic parlance. Both groups received either Pūga Khan.d.a or placebo, in empty stomach in the early morning with water, as per the randomisation plan for a period of 45 days. Patients were followed-upto 4 weeks, 43 patients (84%) had completed the trial and no adverse effects were reported. The assessment was done on the basis of changes in seminal parameters and sexual health parameters.
Results: A varying degree of improvement was observed in sexual parameters viz. duration of coitus (P<0.001), frequency of coitus (P<0.01), Sexual desire (P<0.05), penile erection (P<0.01), A significant improvement was seen in duration of coitus (P< 0.001) in the group treated by Pūga Khan.d.a.
Conclusion: The trial drug Pūga Khan.d.a was superior to placebo in reducing the mean sign and symptom score of seminal parameters and sexual health
A Critical Review of Disease Amlapitta (Gastritis)
No full textSurvival of an organism on the earth is always challenged by the nature. Hunger, adverse climatic conditions, protection against wild animals and diseases are important amongst survival. Today due to modern life style and food habits most of the population are suffering from a common disease called as Gastritis. According to recent survey Gastritis is a common medical problem. Up to 10% of people, who come to a hospital emergency department with an abdominal pain, have gastritis. The incidence of gastritis in India is approximately 3 in 869 that is about 12,25,614 people suffering from gastritis out of the total 1,06,50,70,607 population. The seroprevalence studies from Delhi, Hyderabad and Mumbai have shown that by ten years of age more than 50% and by 20 years more than 80% of population is infected with gastritis. In Ayurveda this disease Gastritis is coined as Amlapitta. Here in this present paper Amlapitta disease is reviewed in detail according to Ayurvedic view and Modern view.</jats:p
IMMUNOMODULATORY EFFECT OF BHRINGRAJ SWARAS SHODHIT GANDHAK AND GODUGDHA SHODHIT GANDHAK: A COMPARATIVE INVITRO STUDY
No full textIntroduction: Gandhak is one among the mineral drug explained in Uparasa Varga. It possesses Rasayana property. It attains therapeutic properties with proper Shodhana processes by Godugdha and by Bhringraj Swaras. Assessment of immunomodulatory effect of Bhringraj Swaras Shodhit Gandhak and Godugdha Shodhit Gandhak may provide evidence base for its textual reference and analysis of these Shodhit Gandhak contributes to establish standards for quality control.
Method: Shuddha Gandhak by Godugdha and by Bhringraj Swaras prepared as per Rasaratnasamuchchaya and subjected to Immunomodulatory activity by Neutrophil Function Assay test with four parameters NBT test, phagocytosis, candidacidal assay and Neutrophils locomotion (chemotaxis) test.
Results: In Immuno-modulatory assay different concentrations of Godugdha Shodhit Gandhaka and Bhringraj Swaras Shodhit Gandhaka shown significant increase in phagocytic activity, candidacidal capacity, locomotion and activation of Neutrophils for phagocytosis.
Conclusion: Godugdha Shodhit Gandhaka and Bhringraj Swaras Shodhit Gandhaka shown significant immunomodulatory effect. Statistically there is no significant difference between Godugdha Shodhit Gandhaka and Bhringraj Swaras Shodhit Gandhaka
Comparative study on efficacy of two Ayurvedic formulations by stress induced gastric ulcers and hypothermia
No full textGastric disorders like hyperacidity and ulcers are a common clinical entity. A rational therapy for gastric ulcers still remains elusive and search for safer potential drugs is being carried out. The present comparative experimental study was planned to see the efficacy of two Ayurvedic formulations i.e. Narikela Khanda (Cocus nucifera candy) and Narikela Khanda granules by using swimming stress induced ulcers and hypothermia in albino rats. Wister strain albino rats of either sex were divided into three groups, each group consists of six animals. Here group \u27A\u27 received Narikela Khanda suspension, while group \u27B\u27 received Narikela Khanda granules suspension and group \u27C\u27 received dose of tap water which served as stress control group. Narikela Khanda and Narikela Khanda granules were prepared in house laboratory of the department. Wister strain albino rats of either sex weighing between 150-250g were selected for the study. Effects of both the formulations were assessed on different parameters like change in body weight, effect on rectal temperature and ulcer index. Body weight decrease was seen in both the formulations compared to initial body weight. Both the formulations did not affect the rectal temperature to significant extent in comparison to stress control group. An apparent and statistically highly significant decrease in ulcer index was observed in both the test formulations treated group in comparison to stress control group. The magnitude of anti-ulcer effect was found to be higher in Narikela Khanda granules treated group
Utility of Karya Karana Bhava of Sankhya Darshana in Ayurveda
No full textTo keep with ever changing, ever growing field of research in modern medical sciences the Ayurvedic concepts need to be analyzed and updated in relevance with the developments in the contemporary sciences. The fundamental base of Ayurveda is built on the concepts which are its self developed and adopted by various allied texts and altered. The concepts which are being adopted are not present as it is, but the essence can be felt everywhere in the text. “Karya Karana Bhava” is one such concept given by the Sankhya Darsana and advocated in Ayurveda. In this background, the study on Sankhya Darshana, Tattvas of Sankhya Darshana, and the utility of Karya Karana Bhava in Ayurveda is necessary. Hence, this subject is taken in account to explore it
Stay healthy this monsoon with Ayurvedic lifestyle modifications
No full textRitucharya is the term for the dietary and lifestyle regimens that are based on Earth\u27s seasons. The belief is that illness can be prevented if diet and lifestyle reflect the changes in weather conditions. Ritucharya is the ancient Ayurvedic practice and is comprised of two words, “Ritu” which means season and “Charya” which means regimen or discipline. Ritucharya consists of lifestyle and Ayurvedic diet routine to cope with the bodily and mental impacts caused by seasonal changes as recommended by Ayurveda. Varsha Rutu (Monsoon) brings about vivid changes not only in the nature but also in the body. Our body is more susceptible to health issues during rainy season, because monsoon reduces the digestive fire in our body. Our body constantly gets affected with indigestion problems, viral fever, malaise etc. so we must keep our body resistant against such diseases. Hence this review article discusses the lifestyle modifications needed to preserve then body from diseases originating in Varsha Rutu
Concept of Shodhana procedure with special reference to Guggulu Resin (Commiphora Mukul Linn.)
No full textAyurveda, the science of life is being practiced by Aryans from Vedic period. In the Vedic period Guggulu was a well-known drug in Indigenous System of Medicine. In Atharvaveda it is mentioned to be used both externally and internally. By just consuming the odour of Guggulu, it reduces many diseases. Many properties of Guggulu are described in our classics. Guggulu is the oleoresin of Commiphora Mukul Linn., a plant that is native to India. Its extracts include compounds known for their hypolipidemic properties, the Z- and E- isomers of guggulsterone and its related guggulsterols. Kalpana is the process through which a substance can be transformed in to the form of medicine according to the need. During preparations of various formulations there are various Samskaras which are to be done for potentiating the drug or the formulation. Among all these pharmaceutical processes Shodhana is one of them. In our text, for a single drug many process of Shodhana in different ways have been mentioned. There are different medias explained in literature for Shodhana of Guggulu. According to the media of purification the quality and pharmacological properties of Guggulu will vary. Depending on the change in properties the therapeutic effect may also vary. The present study includes collection of different concepts regarding Shodana of Guggulu as per various classical references
THE SPERMATOGENIC ACTIVITY OF SHUDDHA GANDHAKA AND KAMDEEPAKA RASA - A COMPARATIVE STUDY IN ALBINO RATS
No full textIn last 10 years significant decrease in human fertility has been observed. Male factor contributes to infertility as much as 51.2% according to WHO study of more than 8500 couples. Shuddha Gandhaka and Kamdeepaka Rasa have Vrishya property expected to contribute better in infertility. Gandhaka Shodhana was prepared as per Rasatarangini and Kamdeepaka Rasa as per Bhaishajya Ratnavali, Vajikarana Adhaya, subjected to Spermatogenic activity on albino rats
Method: Kamdeepaka Rasa prepared as per Bhaishajya Ratnavali. Shuddha Gandhaka (9mg), Kamdeepaka Rasa (9mg), milk (0.5ml), male albino rats formed the materials for the study parameter like body weight, biochemical Spermatogenic element, histometric studies and reproductive accessory organ weight were followed.
Results: In analytical study Si, S, Zn, were deducted in Gandhaka, Si, S, Cl, K, Ca, Iron, Mg, Zn, and Cu. Kamdeepaka Rasa has shown significant Spermatogenic activity compare to Gandhaka and milk.
Conclusion: The chemical and phytochemical component and Balya, Brumhna, Rasayana, and Vrishya properties have contributed for Spermatogenic activity thus Kamdeepakarasa may be used in different condition of Male Infertility
Pharmaceutico analytical study of Shodhita Shilajatu
No full textBackground: Shilajatu or Adrija is one of the Maharasa, which is considered as a wonderful medicine in Ayurveda. It is named as it comes out of the stones heated by the sun in summer in the form of thick blackish exudation having many shades. Since it contain stone, mud, wood, sand and various physical and metallic impurities, Shodhana (Purification) of Shilajatu is a mandatory procedure. It has been used as a prime ingredient in many formulations mainly for Prameha, Sotha, Pandu Roga, Kshaya, Swasa, Pliha Vrudhi, Jwara, Agnimandya, Apasmara, etc. Objectives: Shodhana of Ashudha Shilajatu and Physico chemical analysis of Shodhita Shilajatu. Materials & Methods: Bhringaraja Swarasa for Shodhana of Shilajatu. Results:It took 8 days for completion of Shilajatu Shodhana. XRD Analysis report indicates that the sample Shilajatu was Amorphous material. Conclusion: Total yield of Shodhita Shilajatu was 99.6%. The Sample of Shilajatu was found to be Amorphous material in XRD Analysis hence crystal structure was not identified
